liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Programmable bioelectronics in a stimuli-encoded 3D graphene
Linköping University, Department of Physics, Chemistry and Biology, Biosensors and Bioelectronics. Linköping University, Faculty of Science & Engineering.
Sorbonne Universités, Université de Technologie de Compiègne, CNRS Laboratory for Enzyme and Cell Engineering, France.
Sorbonne Universités, Université de Technologie de Compiègne, CNRS Laboratory for Enzyme and Cell Engineering, France.
Sorbonne Universités, Université de Technologie de Compiègne, CNRS Laboratory for Enzyme and Cell Engineering, France.
Show others and affiliations
(English)Manuscript (preprint) (Other academic)
Keyword [en]
Programmable bioelectronics; stimuli-encoded graphene; switchable electrode; smart logic gates
National Category
Physical Chemistry Biochemistry and Molecular Biology
Identifiers
URN: urn:nbn:se:liu:diva-120989OAI: oai:DiVA.org:liu-120989DiVA: diva2:850394
Available from: 2015-09-01 Created: 2015-09-01 Last updated: 2015-09-01Bibliographically approved
In thesis
1. Interfacing nanomaterials for bioelectronic applications
Open this publication in new window or tab >>Interfacing nanomaterials for bioelectronic applications
2015 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The integration of nanomaterials between biological and electronic world has revolutionized the way of understanding how to generate functional bioelectronic device and open a new horizon for the future of bioelectronics. The use of nanomaterials as a versatile interface in the area of bioelectronics offers many practical solutions and recently outshines as an alternative method to overcome technical challenges to control and regulate the mean of communication between biological and electronics systems. Therefore, the interfacing nanomaterials yields broad platform of functional units for the integration as bioelectronic interfaces and starts to have a great importance to many fields within the life science.

In parallel with the advancements for the successful combination of biological and electronic worlds using nanotechnology in a conventional way, a new branch of switchable bioelectronics based on signal-responsive materials and related interfaces have been emerged. The switchable bioelectronics consists of functional interfaces equipped with molecular cue that able to mimic and adapt their natural environment and change physical and chemical properties on demand. These switchable interfaces are essential to develop a range of technologies to understand function and properties of biological systems such as bio-catalysis, control of ion transfer and molecular recognition used in bioelectronics systems.

This thesis focuses on both the integration of functional nanomaterials to improve electrical interfacing between biological system and electronics and also the generation of a dynamic interface having ability to respond real-life physical and chemical changes. The developing of such a dynamic interface allows one to understand how do living system probe and respond their changing environment and also help control and modulate bio-molecular interactions in a confined space using external physical and chemical stimuli. First, the integration of various nanomaterials is described to understand the effect of different surface modifications and morphologies using different materials on the basis of enzyme-based electrochemical sensing of biological analytes. Then, various switchable interfaces including temperature, light and pH, consist of graphene-enzyme and responsive polymer, are developed to control and regulate enzymebased biomolecular reactions. Finally, physically controlled programmable bio-interface which is described by “AND” and “OR” Boolean logic operations using two different stimuli on one electrode, is introduced. Together, the findings presented in this thesis lay the groundwork for the establishment switchable and programmable bioelectronics. The both approaches are promising candidates to provide key building blocks for future practical systems, as well as model systems for fundamental research.

Place, publisher, year, edition, pages
Linköping: Linköping University Electronic Press, 2015. 76 p.
Series
Linköping Studies in Science and Technology. Dissertations, ISSN 0345-7524 ; 1684
National Category
Biochemistry and Molecular Biology Biochemistry and Molecular Biology
Identifiers
urn:nbn:se:liu:diva-120990 (URN)10.3384/diss.diva-120990 (DOI)978-91-7519-028-0 (print) (ISBN)
Public defence
2015-09-07, Planck, Fysikhuset, Campus Valla, Linköping, 13:15 (English)
Opponent
Supervisors
Available from: 2015-09-01 Created: 2015-09-01 Last updated: 2016-06-07Bibliographically approved

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Parlak, OnurTurner, Anthony P. FTiwari, Ashutosh
By organisation
Biosensors and BioelectronicsFaculty of Science & Engineering
Physical ChemistryBiochemistry and Molecular Biology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 116 hits
ReferencesLink to record
Permanent link

Direct link