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Synthesis and electrochemical characterisation of processable polypyrrole boronic acid derivatives for carbohydrate binding
Linköping University, Department of Physics, Chemistry and Biology, Biosensors and Bioelectronics. Linköping University, Faculty of Science & Engineering.
2015 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Conducting polymers have been widely explored for many different purposes including sensing. In thisthesis the conducive properties of pyrrole and the carbohydrate binding properties of boronic acid iscombined to make a reagent-free detector for carbohydrates. The polymer is manufactured in form ofparticles in the μm scale to create a porous film which has a high surface to volume ratio.The material was characterised and the binding properties were evaluated for galactose and glucose.Proof of binding was found via both electrochemical methods and QCM-D. A correlation between R2 value and concentration of substrate was found which enables measurement of concentration of carbohydratesin unknown samples.

Place, publisher, year, edition, pages
2015. , 57 p.
Keyword [en]
Conducting polymers, polypyrrole, boronic acid, carbohydrates, reagent-free detection.
National Category
Other Biological Topics
URN: urn:nbn:se:liu:diva-121652ISRN: LITH-IFM-A-EX--15/3071—SEOAI: diva2:857991
Subject / course
Chemical Biology
2015-08-19, Röntgen, Fysikhuset, Linköping, 15:00 (English)
Available from: 2015-10-01 Created: 2015-09-30 Last updated: 2015-10-01Bibliographically approved

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Bunnfors, Kalle
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Biosensors and BioelectronicsFaculty of Science & Engineering
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