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Differences between hypothetical and experience-based value sets for EQ-5D used in Sweden: Implications for decision makers
Linköping University, Department of Medical and Health Sciences, Division of Health Care Analysis. Linköping University, Faculty of Medicine and Health Sciences.
Linköping University, Department of Medical and Health Sciences, Division of Health Care Analysis. Linköping University, Faculty of Medicine and Health Sciences.
Linköping University, Department of Medical and Health Sciences, Division of Health Care Analysis. Linköping University, Faculty of Medicine and Health Sciences.
Linköping University, Department of Medical and Health Sciences, Division of Health Care Analysis. Linköping University, Faculty of Medicine and Health Sciences.
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2015 (English)In: Scandinavian Journal of Public Health, ISSN 1403-4948, E-ISSN 1651-1905, Vol. 43, no 8, 848-854 p.Article in journal (Refereed) Published
Abstract [en]

Aims: A number of value sets are available today for converting EQ-5D questionnaire responses to quality-adjusted life year-weights used in health economic evaluations. The aim of this study is to analyse the differences between the commonly used hypothetical UK value set and the newly introduced Swedish experience-based value set and to evaluate health economic implications of such differences on policy decisions. Methods: Differences between the two value sets were studied using two methods: a comparison of health states and improvements as well as an empirical comparison. In the comparison of health states and improvements, the valuations of all EQ-5D states and all pure improvements were compared. In the empirical study, a database of 23,925 individuals was used to identify patient groups that could be affected by the implementation of the Swedish experience-based value set. Results: The comparison of health states and possible improvements showed that only three health states were assigned a lower quality-adjusted life year-weight and most improvements were given smaller absolute values if the experience-based value set was used. The empirical comparison showed that severe conditions were assigned higher values when using the experience-based value set. Conclusions: The Swedish experience-based value set seems to render a higher estimated level of health-related quality of life in virtually all health conditions compared to the hypothetical UK value set. In extension, health-related quality of life enhancing interventions are likely to be given higher priority in decision-making situations where hypothetical values are used to construct quality-adjusted life year-weights. In situations where experience-based quality-adjusted life year-weights are used, life-prolonging interventions would be prioritised.

Place, publisher, year, edition, pages
SAGE PUBLICATIONS LTD , 2015. Vol. 43, no 8, 848-854 p.
Keyword [en]
Economic evaluations; quality-adjusted life years; EQ-5D
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-123133DOI: 10.1177/1403494815596910ISI: 000364636600010PubMedID: 26271493OAI: oai:DiVA.org:liu-123133DiVA: diva2:877720
Note

Funding Agencies|County Council of Ostergotland

Available from: 2015-12-07 Created: 2015-12-04 Last updated: 2017-12-01

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Aronsson, MattiasHusberg, MagnusKalkan, AlminaEckard, NathalieAlwin, Jenny

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