Porous functional nanofilms for designing bioinspired sensor surfaces
2015 (English)In: Proceeding of Advanced Materials World Congress / [ed] Ashutosh Tiwari, Linköping, Sweden: VBRI Press , 2015Conference paper, Abstract (Other academic)
Bio-mimicking of recognition features typical of biological molecules such as aminoacids, peptides, nucleic acid etc. is leading to the design and development of novel functional (artificial) materials for chemical/biochemical sensing applications. The insertion of biological molecules or their active sites into the backbone of synthetic polymers is one of the possible ways to achieve this. Herein, we synthesised a polymerisable derivative of an amino acid (L-histidine) through a set of reactions with 1-(1Hbenzo[d][1,2,3]triazol-1-yl)-2-methylprop-2-en-1-one (MA-Bt), since amino acid residues are the origin for the functional properties and highly selective substrate-binding ability of many extended biological structures. We obtained a functional monomer methacryloylamidohistidine (MAH), which was polymerised with 2-hydroxyethyl methacrylate in presence of polyvinyl alcohol (PVA) on a gold surface. The aim of using PVA was to obtain highly porous polymeric structure. For control purpose, polymers without MAH and PVA were also synthesised. The morphology of the polymeric film on gold surface was characterized with scanning electron microscopy (SEM) and atomic force microscopy (AFM). The obtained polymer showed significant affinity for Cu2+. The electrochemical behaviour of the polymeric films was systematically investigated with differential pulse voltammetry (DPV). The presence of pores was shown to significantly improve the recognition performance of the film.
Place, publisher, year, edition, pages
Linköping, Sweden: VBRI Press , 2015.
Bio - mimicking ; amino aci ds; porous polymeric film
IdentifiersURN: urn:nbn:se:liu:diva-123692DOI: 10.5185/amwc.2015ISBN: 9789188252005OAI: oai:DiVA.org:liu-123692DiVA: diva2:891966
Advanced Materials World Congress, Stockholm, Sweden, 22-16 August 2015