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An overview of pregnancy and fertility issues in breast cancer patients
Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Department of Oncology.
2015 (English)In: Annals of Medicine, ISSN 0785-3890, E-ISSN 1365-2060, Vol. 47, no 8, 673-678 p.Article, review/survey (Refereed) PublishedText
Abstract [en]

Breast cancer is one of the most common malignancies of women in the reproductive years. In the Western world there is a trend towards delaying pregnancy to later in life, and in combination with an increased incidence of breast cancer an increased number of women are diagnosed with breast cancer before they have completed their reproductive plans. In addition, breast cancer during pregnancy may affect an increased number of women as the childbearing years are delayed. The survival rate after breast cancer has improved during the last decades, and many young breast cancer survivors will consider a pregnancy subsequent to the completion of adjuvant breast cancer therapy. Traditionally, many women are advised against a pregnancy due to a fear of increased risk of recurrence, especially women with estrogen receptor-positive breast cancer. Due to feasibility issues, evidence from large prospective randomized trials is missing regarding the safety of pregnancy after breast cancer. Today guidelines are based on cohort studies and population-based registry evidence with its limitations. Overall, data suggest that pregnancy after breast cancer therapy is safe, and the current evidence is summarized in this overview.

Place, publisher, year, edition, pages
TAYLOR & FRANCIS LTD , 2015. Vol. 47, no 8, 673-678 p.
Keyword [en]
Breast cancer; estrogen receptor; fertility; mammary cancer; pregnancy
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-123841DOI: 10.3109/07853890.2015.1096953ISI: 000366590600005PubMedID: 26542739OAI: oai:DiVA.org:liu-123841DiVA: diva2:892850
Available from: 2016-01-11 Created: 2016-01-11 Last updated: 2016-03-10

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The full text will be freely available from 2016-11-05 00:00
Available from 2016-11-05 00:00

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Dabrosin, Charlotta
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