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The value of telemonitoring and ICT-guided disease management in heart failure: Results from the IN TOUCH study
University of Groningen, Netherlands.
University of Groningen, Netherlands.
University of Groningen, Netherlands.
University of Groningen, Netherlands.
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2016 (English)In: International Journal of Medical Informatics, ISSN 1386-5056, E-ISSN 1872-8243, Vol. 85, no 1, 53-60 p.Article in journal (Refereed) PublishedText
Abstract [en]

Aim: It is still unclear whether telemonitoring reduces hospitalization and mortality in heart failure (HF) patients and whether adding an Information and Computing Technology-guided-disease-management-system (ICT-guided-DMS) improves clinical and patient reported outcomes or reduces healthcare costs. Methods: A multicenter randomized controlled trial was performed testing the effects of INnovative ICT-guided-DMS combined with Telemonitoring in OUtpatient clinics for Chronic HF patients (IN TOUCH) with in total 179 patients (mean age 69 years; 72% male; 77% in New York Heart Association Classification (NYHA) III-IV; mean left ventricular ejection fraction was 28%). Patients were randomized to ICT-guided-DMS or to ICT-guided-DMS + telemonitoring with a follow-up of nine months. The composite endpoint included mortality, HF-readmission and change in health-related quality of life (HR-QoL). Results: In total 177 patients were eligible for analyses. The mean score of the primary composite endpoint was -0.63 in ICT-guided-DMS vs. -0.73 in ICT-guided-DMS + telemonitoring (mean difference 0.1,95% CI: -0.67 +0.82, p = 0.39). All-cause mortality in ICT-guided-DMS was 12% versus 15% in ICT-guided-DMS + telemonitoring (p = 0.27); HF-readmission 28% vs. 27% p = 0.87; all-cause readmission was 49% vs. 51% (p = 0.78). HR-QoL improved in most patients and was equal in both groups. Incremental costs were 1360 in favor of ICT-guided-DMS. ICT-guided-DMS + telemonitoring had significantly fewer HF-outpatient-clinic visits (p < 0.01). Conclusion: ICT-guided-DMS + telemonitoring for the management of HF patients did not affect the primary and secondary endpoints. However, we did find a reduction in visits to the HF-outpatient clinic in this group suggesting that telemonitoring might be safe to use in reorganizing HF-care with relatively low costs. (C) 2015 The Authors. Published by Elsevier Ireland Ltd. This is an open access article under the CC BY-NC-ND license (

Place, publisher, year, edition, pages
ELSEVIER IRELAND LTD , 2016. Vol. 85, no 1, 53-60 p.
Keyword [en]
Heart failure; Disease management; Telemonitoring; ICT-guided disease management; Computer decision support
National Category
URN: urn:nbn:se:liu:diva-124489DOI: 10.1016/j.ijmedinf.2015.10.001ISI: 000367356900007PubMedID: 26514079OAI: diva2:899678

Funding Agencies|Dutch Ministry of Health, Department of Pharmaceutical Affairs and Medical Technology (GMT)

Available from: 2016-02-02 Created: 2016-02-01 Last updated: 2016-03-03

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Jaarsma, Tiny
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Division of Health, Activity and CareFaculty of Medicine and Health Sciences
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