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Fuzzy scaling analysis of a mouse mutant with brain morphological changes
School of Information Technology and Electrical Engineering, The University of New South Wales, Canberra, Australia.ORCID iD: 0000-0002-4255-5130
Biomolecular and Physical Sciences, and Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, Queensland, Australia.
Biomolecular and Physical Sciences, and Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, Queensland, Australia.
2009 (English)In: Information Technology in Biomedicine, IEEE Transactions on, ISSN 1089-7771, Vol. 13, no 4, p. 629-635Article in journal (Refereed) Published
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Abstract [en]

Scaling behavior inherently exists in fundamental biological structures, and the measure of such an attribute can only be known at a given scale of observation. Thus, the properties of fractals and power-law scaling have become attractive for research in biology and medicine because of their potential for discovering patterns and characteristics of complex biological morphologies. Despite the successful applications of fractals for the life sciences, the quantitative measure of the scale invariance expressed by fractal dimensions is limited in more complex situations, such as for histopathological analysis of tissue changes in disease. In this paper, we introduce the concept of fuzzy scaling and its analysis of a mouse mutant with postnatal brain morphological changes.

Place, publisher, year, edition, pages
Institute of Electrical and Electronics Engineers (IEEE), 2009. Vol. 13, no 4, p. 629-635
Keywords [en]
Fractals, fuzzy c-means (FCMs), fuzzy sets (FCMs), mouse brains, peroxisomal dysfunction, scaling, Zellweger syndrome
National Category
Bioinformatics and Systems Biology
Identifiers
URN: urn:nbn:se:liu:diva-125031DOI: 10.1109/TITB.2009.2019638ISI: 000267835800027PubMedID: 19369166Scopus ID: 2-s2.0-67749147639OAI: oai:DiVA.org:liu-125031DiVA, id: diva2:902763
Available from: 2016-02-12 Created: 2016-02-12 Last updated: 2017-12-22Bibliographically approved

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Pham, Tuan D

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CiteExportLink to record
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Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
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  • Other style
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  • de-DE
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  • en-US
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  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
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Output format
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