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New Insights into Peptide-Silver Nanoparticle Interaction: Deciphering the Role of Cysteine and Lysine in the Peptide Sequence
Kansas State University, KS 66506 USA; Kansas State University, KS 66506 USA.
University of Ottawa, Canada.
University of Victoria, Canada.
University of Victoria, Canada.
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2016 (English)In: Langmuir, ISSN 0743-7463, E-ISSN 1520-5827, Vol. 32, no 1, 265-273 p.Article in journal (Refereed) PublishedText
Abstract [en]

We studied the interaction of four new pentapeptides with spherical silver nanoparticles. Our findings indicate that the combination of the thiol in Cys and amines in Lys/Arg residues is critical to providing stable protection for the silver surface. Molecular simulation reveals the atomic scale interactions that underlie the observed stabilizing effect of these peptides, while yielding qualitative agreement with experiment for ranking the affinity of the four pentapeptides for the silver surface.

Place, publisher, year, edition, pages
AMER CHEMICAL SOC , 2016. Vol. 32, no 1, 265-273 p.
National Category
Physical Sciences
URN: urn:nbn:se:liu:diva-125155DOI: 10.1021/acs.langmuir.5b03601ISI: 000368321700031PubMedID: 26675437OAI: diva2:903416

Funding Agencies|NSERC Discovery (EIA); University of Ottawa Heart Institute (EIA); Kansas Bioscience Authority funds; Kansas State University Global Food Systems Innovation Program [383GFS]; NSF [CNS-1006860, EPS-1006860, EPS-0919443]; National Science Foundation [ACI-1053575]; NSERC Discovery Grant [RGPIN-121389-2012]; Swedish Research Council [621-2012-4286]; [FONDECYT 3140288]

Available from: 2016-02-15 Created: 2016-02-15 Last updated: 2016-02-15

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Ravichandran, RanjithkumarPhopase, Jaywant
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