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The Swedish CArdioPulmonary BioImage Study: objectives and design
University of Gothenburg / Sahlgrenska University Hospital.
Lund University.
Umeå University.
Sahlgrenska University Hospital / University of Gothenburg.
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2015 (English)In: Journal of Internal Medicine, ISSN 0954-6820, E-ISSN 1365-2796, Vol. 278, no 6, 645-659 p.Article in journal (Refereed) Published
Abstract [en]

Cardiopulmonary diseases are major causes of death worldwide, but currently recommended strategies for diagnosis and prevention may be outdated because of recent changes in risk factor patterns. The Swedish CArdioPulmonarybioImage Study (SCAPIS) combines the use of new imaging technologies, advances in large-scale 'omics' and epidemiological analyses to extensively characterize a Swedish cohort of 30 000 men and women aged between 50 and 64 years. The information obtained will be used to improve risk prediction of cardiopulmonary diseases and optimize the ability to study disease mechanisms. A comprehensive pilot study in 1111 individuals, which was completed in 2012, demonstrated the feasibility and financial and ethical consequences of SCAPIS. Recruitment to the national, multicentre study has recently started.

Place, publisher, year, edition, pages
2015. Vol. 278, no 6, 645-659 p.
Keyword [en]
cardiovascular; epidemiology; metabolism; pulmonary; trial design
National Category
Public Health, Global Health, Social Medicine and Epidemiology
URN: urn:nbn:se:liu:diva-125531DOI: 10.1111/joim.12384ISI: 000375425100001PubMedID: 26096600OAI: diva2:906926

Funding agencies:  Swedish Heart and Lung Foundation; Knut and Alice Wallenberg Foundation; Swedish Research Council; VINNOVA (Swedens innovation agency)

Available from: 2016-02-25 Created: 2016-02-25 Last updated: 2016-05-19

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Engvall, JanÖstgren, Carl JohanPersson, Anders
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Faculty of Medicine and Health SciencesCenter for Medical Image Science and Visualization (CMIV)Department of Clinical Physiology in LinköpingDivision of Drug ResearchDivision of Community MedicineFaculty of Health SciencesPrimary Health Care in MotalaDivision of Radiological SciencesDepartment of Radiology in Linköping
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Journal of Internal Medicine
Public Health, Global Health, Social Medicine and Epidemiology

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