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Unexpected gender bias among organ donors in Sweden during 2009-2013. A nationwide observational study.
Linköping University, Department of Medical and Health Sciences, Division of Cardiovascular Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Heart and Medicine Center, Department of Thoracic and Vascular Surgery.
Central Hospital, Kristianstad, Sweden.
2015 (English)In: Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, E-ISSN 1399-6576, Vol. 59, no Suppl. 121, O13-09Article in journal, Meeting abstract (Other academic) Published
Abstract [en]

Introduction: The  gap  between the  number of  organ  donors   and patients on waiting lists for transplantation is wide  globally. Understanding  reasons   for  variation in  organ  donation  between and  within  countries may  lead  to  increased availability of organs for transplantation.  The  purpose of  the  present analysis   was  to examine age and  gender of organ  donors  in Sweden.

Methods:   All  deaths  in  Swedish   ICUs   during  2009–2013  were examined using  a prospectively determined protocol  comprising 10 primary questions. Protocols  were sent electronically to the  Swed- ish  Intensive   Care  Registry   (SIR) for  validation and   then joined with  the  appropriate ICU admission in the  SIR database. The rela- tionship between organ  donation and gender  was analysed using logistic  regression adjusted for  age  and comorbidities (as  defined in the SAPS3 model)  and  presented as odds  ratios  (OR).

Results:   The female to male ratio (F/M) was 0.72 in ICU admissions and  ICU deaths, while the  organ  donor  F/M was  1.06. Almost  all organ  donors  (98%) were found  in 4 major diagnostic groups which all showed a disproportionate high female donor  rate (Table). Mean age in female organ donors  was 54.9 (SD 16.5) years. and in men 53.5 (18.3) years,  P = 0.48. The crude  female  OR for becoming a donor was 1.47 (95% CI: 1.25–1.74, P < 0.001), and the adjusted OR was 1.55 (95% CI: 1.28–1.88, P < 0.001).

Table 1 Source: https://www.eventure-online.com/parthen-uploads/154/SSAI/img1_264985_Nxx2LShLTc.jpg.

Conclusion: During the critical pathway for organ donation after brain death the F/M ratio unexpectedly rose. Why and when  men became underrepresented in this pathway needs further study.

Place, publisher, year, edition, pages
Wiley-Blackwell, 2015. Vol. 59, no Suppl. 121, O13-09
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-125567DOI: 10.1111/aas.12556OAI: oai:DiVA.org:liu-125567DiVA: diva2:907061
Conference
33rd Congress of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine, Matters of the heart, Reykavik, Iceland, 10-12 June 2015
Available from: 2016-02-26 Created: 2016-02-26 Last updated: 2016-04-11Bibliographically approved

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Walther, Sten
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Division of Cardiovascular MedicineFaculty of Medicine and Health SciencesDepartment of Thoracic and Vascular Surgery
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