liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Strong Maternal Effects on Gene Expression inArabidopsis lyrata Hybrids
Molecular Ecology and Evolution Lab, Department of Biology, Lund University, Lund, Sweden.
Plant Ecology and Evolution, Department of Ecology and Genetics, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden.
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, Faculty of Science & Engineering. Department of Ecology and Genetics, Evolutionary Biology Centre, Uppsala University.
Plant Ecology and Evolution, Department of Ecology and Genetics, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden.
Show others and affiliations
2016 (English)In: Molecular Biology and Evolution, ISSN 0737-4038, Vol. 33, no 4, 984-994 p.Article in journal (Refereed) Published
Abstract [en]

Hybridization between populations or species can have pronounced fitness consequences. Yet little is known about howhybridization affects gene regulation. Three main models have been put forward to explain gene expression patterns inhybrids: additive, dominance, or parental effects. Here, we use high throughput RNA-sequencing to examine the extent towhich hybrid gene expression follows predictions by each of the three models. We performed a reciprocal crossingexperiment between two differentiated populations of the perennial herb Arabidopsis lyrata and sequenced RNA inrosette leaves of 12-week-old plants grown in greenhouse conditions. The two parental populations had highly differentiatedgene expression patterns. In hybrids, a majority of genes showed intermediate expression relative to that of theirparental populations (i.e., additive effects), but expression was frequently more similar to the maternal than to theirpaternal population (i.e., maternal effects). Allele-specific expression analyses showed that in the vast majority of cases,genes with pronounced maternal effect expressed both the maternal and the paternal allele. Maternal effects on hybridgene expression have rarely been documented previously and our study suggests it could be more common thanpreviously assumed. Whether the maternal effect on gene expression persists to later life-stages, and whether thevariation in gene expression is manifested in other aspects of the phenotype, remain to be elucidated. Our findingsare relevant for understanding the consequences of outbreeding and hybridization and open up several questions forfuture studies.

Place, publisher, year, edition, pages
Oxford University Press, 2016. Vol. 33, no 4, 984-994 p.
Keyword [en]
hybridization, gene expression, maternal effect, additive effect, Arabidopsis lyrata, RNA-Seq
National Category
Genetics
Identifiers
URN: urn:nbn:se:liu:diva-125904DOI: 10.1093/molbev/msv342ISI: 000374226700011PubMedID: 26685177OAI: oai:DiVA.org:liu-125904DiVA: diva2:909598
Available from: 2016-03-07 Created: 2016-03-07 Last updated: 2016-05-12

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Hagenblad, Jenny
By organisation
BiologyFaculty of Science & Engineering
Genetics

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 429 hits
ReferencesLink to record
Permanent link

Direct link