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Resistance training for hot flushes in postmenopausal women: Randomized controlled trial protocol
Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Linköping University, Faculty of Medicine and Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center of Paediatrics and Gynaecology and Obstetrics, Department of Gynaecology and Obstetrics in Linköping.
Linköping University, Department of Medical and Health Sciences, Division of Physiotherapy. Linköping University, Faculty of Medicine and Health Sciences.ORCID iD: 0000-0002-1533-6872
Linköping University, Department of Clinical and Experimental Medicine, Division of Clinical Sciences. Region Östergötland, Center of Paediatrics and Gynaecology and Obstetrics, Department of Gynaecology and Obstetrics in Linköping. Linköping University, Faculty of Medicine and Health Sciences.
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2016 (English)In: Maturitas, ISSN 0378-5122, E-ISSN 1873-4111, Vol. 85, 96-103 p.Article in journal (Refereed) PublishedText
Abstract [en]

Objectives: Hot flushes and night sweats affect 75% of all women after menopause and is a common reason for decreased quality of life in mid-aged women. Hormone therapy is effective in ameliorating symptoms but cannot be used by all women due to contraindications and side effects. Engagement in regular exercise is associated with fewer hot flushes in observational studies, but aerobic exercise has not proven effective in randomized controlled trials. It remains to be determined whether resistance training is effective in reducing hot flushes and improves quality of life in symptomatic postmenopausal women. The aim of this study is to investigate the effect of standardized resistance training on hot flushes and other health parameters in postmenopausal women. Study design: This is an open, parallel-group, randomized controlled intervention study conducted in Linkoping, Sweden. Sixty symptomatic and sedentary postmenopausal women with a mean of at least four moderate to severe hot flushes per day or 28 per week will be randomized to an exercise intervention or unchanged physical activity (control group). The intervention consists of 15 weeks of standardized resistance training performed three times a week under supervision of a physiotherapist. Main outcome measures: The primary outcome is hot flush frequency assessed by self-reported hot flush diaries, and the difference in change from baseline to week 15 will be compared between the intervention group and the control group. Conclusion: The intention is that this trial will contribute to the evidence base regarding effective treatment for hot flushes. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

Place, publisher, year, edition, pages
ELSEVIER IRELAND LTD , 2016. Vol. 85, 96-103 p.
Keyword [en]
Menopause; Hot flashes; Resistance training; Vasomotor symptoms; Exercise; Study protocol
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-126250DOI: 10.1016/j.maturitas.2015.12.015ISI: 000370897300016PubMedID: 26857887OAI: oai:DiVA.org:liu-126250DiVA: diva2:913450
Note

Funding Agencies|Swedish Research Council [2014-2781]; Region Ostergotland, Sweden

Available from: 2016-03-21 Created: 2016-03-21 Last updated: 2016-05-04

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Berin, EmiliaHammar, MatsLindblom, HannaLindh Åstrand, LottaSpetz, Anna-Clara
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Division of Clinical SciencesFaculty of Medicine and Health SciencesDepartment of Gynaecology and Obstetrics in LinköpingDivision of Physiotherapy
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