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Impaired visual contrast sensitivity in epileptic patients treated with carbamazepine.
Karolinska Inst, Stockholm, Sweden.
Karolinska Inst, Stockholm, Sweden.
Karolinska Inst, Stockholm, Sweden.
1988 (English)In: Archives of Neurology, ISSN 0003-9942, E-ISSN 1538-3687, Vol. 45, no 8, 897-900 p.Article in journal (Refereed) PublishedText
Abstract [en]

Critical flicker fusion frequencies and visual contrast sensitivity were determined in 27 adult epileptic patients receiving carbamazepine monotherapy and in 24 healthy, drug-free control subjects. Flicker fusion thresholds were the same in patients and control subjects, whereas the contrast sensitivity was significantly reduced in the patient group at all spatial frequencies. There was a significant negative correlation between the plasma concentration of carbamazepine and the contrast sensitivity at 11.4 and 22.8 cycles per degree, indicating that the reduced contrast sensitivity was due to the drug therapy.

Place, publisher, year, edition, pages
1988. Vol. 45, no 8, 897-900 p.
National Category
Neurology
Identifiers
URN: urn:nbn:se:liu:diva-126373DOI: 10.1001/archneur.1988.00520320095021OAI: oai:DiVA.org:liu-126373DiVA: diva2:913928
Available from: 2016-03-23 Created: 2016-03-23 Last updated: 2016-04-08

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