liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
The Second Filters Second Coming
Oregon Health and Science University, OR 97201 USA.
Oregon Health and Science University, OR 97201 USA; South University of Science and Technology China, Peoples R China.
Oregon Health and Science University, OR 97201 USA; Fourth Mil Medical University, Peoples R China.
Oregon Health and Science University, OR 97201 USA.
Show others and affiliations
2015 (English)In: MECHANICS OF HEARING: PROTEIN TO PERCEPTION, AMER INST PHYSICS , 2015, Vol. 1703, no 040003Conference paper (Refereed)Text
Abstract [en]

We measured sound-evoked vibrations at the stereociliary side of inner and outer hair cells and their surrounding supporting cells, using optical coherence tomography interferometry in living anesthetized guinea pigs. Our measurements demonstrate a gradient in frequency tuning among different cell types, going from a high best frequency at the inner hair cells to a lower one at the Hensen cells. This causes the locus of maximum inner hair cell activation to be shifted toward the apex of the cochlea as compared to the outer hair cells. These observations show that additional processing and filtering of acoustic signals occurs within the organ of Corti prior to inner hair cell excitation, thus reinstating a transformed second filter as a mechanism contributing to cochlear frequency tuning.

Place, publisher, year, edition, pages
AMER INST PHYSICS , 2015. Vol. 1703, no 040003
Series
, AIP Conference Proceedings, ISSN 0094-243X
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-127076DOI: 10.1063/1.4939337ISI: 000372065400024ISBN: 978-0-7354-1350-4OAI: oai:DiVA.org:liu-127076DiVA: diva2:919330
Conference
12th International Workshop on the Mechanics of Hearing
Available from: 2016-04-13 Created: 2016-04-13 Last updated: 2016-04-13

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Fridberger, Anders
By organisation
Division of Cell BiologyFaculty of Medicine and Health Sciences
Clinical Medicine

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 151 hits
ReferencesLink to record
Permanent link

Direct link