The Second Filters Second Coming
2015 (English)In: MECHANICS OF HEARING: PROTEIN TO PERCEPTION, AMER INST PHYSICS , 2015, Vol. 1703, no 040003Conference paper (Refereed)Text
We measured sound-evoked vibrations at the stereociliary side of inner and outer hair cells and their surrounding supporting cells, using optical coherence tomography interferometry in living anesthetized guinea pigs. Our measurements demonstrate a gradient in frequency tuning among different cell types, going from a high best frequency at the inner hair cells to a lower one at the Hensen cells. This causes the locus of maximum inner hair cell activation to be shifted toward the apex of the cochlea as compared to the outer hair cells. These observations show that additional processing and filtering of acoustic signals occurs within the organ of Corti prior to inner hair cell excitation, thus reinstating a transformed second filter as a mechanism contributing to cochlear frequency tuning.
Place, publisher, year, edition, pages
AMER INST PHYSICS , 2015. Vol. 1703, no 040003
, AIP Conference Proceedings, ISSN 0094-243X
IdentifiersURN: urn:nbn:se:liu:diva-127076DOI: 10.1063/1.4939337ISI: 000372065400024ISBN: 978-0-7354-1350-4OAI: oai:DiVA.org:liu-127076DiVA: diva2:919330
12th International Workshop on the Mechanics of Hearing