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2016 European Guideline on the management of non-gonococcal urethritis
School of Social and Community Medicine, University of Bristol, UK.
Bristol Sexual Health Centre, University Hospitals Bristol NHS Foundation Trust, UK.
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuro and Inflammation Science. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Local Health Care Services in West Östergötland, Research & Development Unit in Local Health Care.ORCID iD: 0000-0001-8336-9767
Department of Dermatology, New Cross Hospital, UK..
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2016 (English)In: International Journal of STD and AIDS (London), ISSN 0956-4624, E-ISSN 1758-1052Article in journal (Refereed) Epub ahead of print
Abstract [en]

We present the updated International Union against Sexually Transmitted Infections guideline for the management of non-gonococcal urethritis in men. This guideline recommends confirmation of urethritis in symptomatic men before starting treatment. It does not recommend testing asymptomatic men for the presence of urethritis. All men with urethritis should be tested for Chlamydia trachomatis and Neisseria gonorrhoeae and ideally M. genitalium using a NAAT as this is highly likely to improve clinical outcomes. If a NAAT is positive for gonorrhoea, a culture should be performed before treatment. In view of the increasing evidence that azithromycin 1 g may result in the development of antimicrobial resistance in Mycoplasma genitalium azithromycin 1 g is no longer recommended as first line therapy, which should be doxycycline 100 mg bd for 7 days. If azithromycin is to be prescribed an extended of 500 mg, then 250 mg daily for 4 days is to be preferred over 1 g stat. In men with persistent NGU, M. genitalium NAAT testing is recommended if not previously undertaken, as is Trichomonas vaginalis NAAT testing in populations where T. vaginalis is detectable in >2% of symptomatic women.

Place, publisher, year, edition, pages
Sage Publications, 2016.
Keyword [en]
Chlamydia (Chlamydia trachomatis); non-gonococcal urethritis
National Category
Dermatology and Venereal Diseases Infectious Medicine
URN: urn:nbn:se:liu:diva-128227DOI: 10.1177/0956462416648585PubMedID: 27147267OAI: diva2:930262
Available from: 2016-05-23 Created: 2016-05-23 Last updated: 2016-06-10Bibliographically approved

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Falk, Lars
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Division of Neuro and Inflammation ScienceFaculty of Medicine and Health SciencesResearch & Development Unit in Local Health Care
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International Journal of STD and AIDS (London)
Dermatology and Venereal DiseasesInfectious Medicine

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