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Detection of nuclear buds based on ellipse fitting
CSIRO Mathematics, Informatics and Statistics, North Ryde, NSW 1670, Australia /UNSW@ADFA, Canberra, ACT 2600, Australia.
CSIRO Mathematics, Informatics and Statistics, North Ryde, NSW 1670, Australia.
School of Engineering and Information Technology, UNSW@ADFA, Canberra, ACT 2600, Australia.ORCID iD: 0000-0002-4255-5130
CSIRO Mathematics, Informatics and Statistics, North Ryde, NSW 1670, Australia.
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2010 (English)Conference paper (Refereed)Text
Abstract [en]

Assays of micronucleus are extensively used in genotoxicity testing and in monitoring of human exposure to genotoxic materials. As nuclear buds could be a new source of micronuclei formed in interphase, the assay of contents of nuclear bud in normal and comparison group is needed. In this paper, we proposed a new automatic nuclear buds detection algorithm based on ellipse fitting. Experimental results show that our algorithm is effective and efficient. We believe that this is the first report on automated nuclear bud detection for DNA damage scoring.

Place, publisher, year, edition, pages
2010. 178-183 p.
Keyword [en]
Nuclear buds; Bud detection; Ellipse fitting; DNA damage scoring;
National Category
Computer Science
Identifiers
URN: urn:nbn:se:liu:diva-127861DOI: 10.1109/DICTA.2010.41ISBN: 978-0-7695-4271-3ISBN: 978-1-4244-8816-2OAI: oai:DiVA.org:liu-127861DiVA: diva2:930664
Conference
2010 Digital Image Computing: Techniques and Applications (DICTA).1-3 December 2010,Sydney, NSW
Available from: 2016-05-25 Created: 2016-05-13 Last updated: 2016-06-10

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Pham, Tuan D
Computer Science

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