Detection of nuclear buds based on ellipse fitting
2010 (English)Conference paper (Refereed)Text
Assays of micronucleus are extensively used in genotoxicity testing and in monitoring of human exposure to genotoxic materials. As nuclear buds could be a new source of micronuclei formed in interphase, the assay of contents of nuclear bud in normal and comparison group is needed. In this paper, we proposed a new automatic nuclear buds detection algorithm based on ellipse fitting. Experimental results show that our algorithm is effective and efficient. We believe that this is the first report on automated nuclear bud detection for DNA damage scoring.
Place, publisher, year, edition, pages
2010. 178-183 p.
Nuclear buds; Bud detection; Ellipse fitting; DNA damage scoring;
IdentifiersURN: urn:nbn:se:liu:diva-127861DOI: 10.1109/DICTA.2010.41ISBN: 978-0-7695-4271-3ISBN: 978-1-4244-8816-2OAI: oai:DiVA.org:liu-127861DiVA: diva2:930664
2010 Digital Image Computing: Techniques and Applications (DICTA).1-3 December 2010,Sydney, NSW