liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Test–retest reliability of rapid whole body and compartmental fat volume quantification on a widebore 3T MR system in normal-weight, overweight, and obese subjects
Department of Radiology, Norfolk & Norwich University Hospital, UK.
Department of Radiology, Norfolk & Norwich University Hospital, UK.
Linköping University, Center for Medical Image Science and Visualization (CMIV). Linköping University, Department of Medical and Health Sciences, Division of Radiological Sciences. (Advanced MR Analytics AB)
Department of Radiology, Norfolk & Norwich University Hospital, UK.
Show others and affiliations
2016 (English)In: Journal of Magnetic Resonance Imaging, ISSN 1053-1807, E-ISSN 1522-2586Article in journal (Refereed) Epub ahead of print
Abstract [en]

Purpose

To measure the test–retest reliability of rapid (<15 min) whole body and visceral fat volume quantification in normal and obese subjects on a widebore 3T MR system and compare it with conventional manual segmentation.

Materials and Methods

Thirty participants (body mass index [BMI] 20.1–48.6 kg/m2) underwent two whole-body magnetic resonance imaging (MRI) examinations on a widebore 3T machine using a 2-point Dixon technique. Phase sensitive reconstruction and intensity inhomogeneity correction produced quantitative datasets of total adipose tissue (TAT), abdominal subcutaneous adipose tissue (ASAT), and visceral adipose tissue (VAT). The quantification was performed automatically using nonrigid atlas-based segmentation and compared with manual segmentation (SliceOmatic).

Results

The mean TAT was 31.74 L with a coefficient of variation (CV) of 0.79% and a coefficient of repeatability (CR) of 0.49 L. The ASAT was 7.92 L with a CV of 2.98% and a CR of 0.46 L. There was no significant difference in the semiautomated and manually segmented VAT (P = 0.73) but there were differences in the reliability of the two techniques. The mean semiautomated VAT was 2.56 L, CV 1.8%, and CR 0.09 L compared to the mean manually segmented VAT of 3.12 L, where the CV was 6.3% and the CR was 0.39 L.

Conclusion

Rapid semiautomated whole body and compartmental fat volume quantification can be derived from a widebore 3T system, for a range of body sizes including obese patients, with “almost perfect” test–retest reliability.

Place, publisher, year, edition, pages
2016.
Keyword [en]
semiautomated quantification; manual segmentation; MRI; adipose; visceral adipose; reliability
National Category
Medical Image Processing Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:liu:diva-128881DOI: 10.1002/jmri.25326PubMedID: 27249363OAI: oai:DiVA.org:liu-128881DiVA: diva2:933407
Available from: 2016-06-04 Created: 2016-06-04 Last updated: 2016-06-22

Open Access in DiVA

The full text will be freely available from 2017-06-01 00:00
Available from 2017-06-01 00:00

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Dahlqvist Leinhard, OlofRomu, ThobiasBorga, Magnus
By organisation
Center for Medical Image Science and Visualization (CMIV)Division of Radiological SciencesMedical InformaticsThe Institute of Technology
In the same journal
Journal of Magnetic Resonance Imaging
Medical Image ProcessingRadiology, Nuclear Medicine and Medical Imaging

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 36 hits
ReferencesLink to record
Permanent link

Direct link