Health-related quality of life up to 1 year after radiotherapy in patients with head and neck cancer (HNC)
2016 (English)In: SpringerPlus, E-ISSN 2193-1801, Vol. 5, no 1, 669Article in journal (Refereed) Published
Detailed symptom specific descriptions of health-related quality of life (HRQOL), using validated questionnaires in patients with head and neck cancer (HNC) are sparse. The aim of the present study was to investigate HRQOL in patients with HNC up to 1 year after radiotherapy (RT), using two standardised questionnaires.
The data for the present study was originally collected in a randomised, prospective study. Forty-seven patients from two RT clinics in Sweden were included to investigate the secondary aim: HRQOL. Data was recorded at baseline, completion of RT, and 3, 6, 12 months after completed RT, using the questionnaire EORTC QLQ-C30-version 3 and the disease-specific module EORTC QLQ-H&N35.
Most symptoms and functions deteriorated significantly by the end of RT, improved gradually by 3 and 6 months and reached baseline levels at 12 months after completed RT. However, 1 year after completed RT there were remaining significant problems in senses, dry mouth and sticky saliva.
Radiation therapy affects health-related quality of life in patients with head and neck cancer, both in the short and long term. Caregivers need management strategies for early detection and treatment of specific problems throughout the treatment period to help in the prevention of long-term symptoms.
Place, publisher, year, edition, pages
Springer, 2016. Vol. 5, no 1, 669
Health-related quality of life, Head and neck cancer, EORTC QLQ C30, QLQ-H&N35, Trismus
IdentifiersURN: urn:nbn:se:liu:diva-128865DOI: 10.1186/s40064-016-2295-1ISI: 000377606500002OAI: oai:DiVA.org:liu-128865DiVA: diva2:933853
Funding agencies: Swedish Cancer Society; Medical Research Council of Southeast Sweden; Department of Radiation Oncology at the University Hospital in Linkoping; County Hospital in Jonkoping; Department of Medical and Health Sciences, Division of Nursing Science, Linkoping2016-06-072016-06-022016-07-13Bibliographically approved