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MicroRNAs as circulating biomarkers in acute coronary syndromes: A review
Linköping University, Faculty of Medicine and Health Sciences. Wilhelminen Hospital, Austria.
Linköping University, Faculty of Medicine and Health Sciences. Wilhelminen Hospital, Austria.
Wilhelminen Hospital, Austria.
Medical University of Vienna, Austria; Ludwig Boltzmann Cluster Cardiovasc Research, Austria.
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2016 (English)In: Vascular pharmacology, ISSN 1537-1891, E-ISSN 1879-3649, Vol. 81, 15-21 p.Article, review/survey (Refereed) PublishedText
Abstract [en]

Coronary artery disease (CAD) and its complications remain the most common cause of death worldwide. Cardiac troponins (cTn) are standard biomarkers used today for diagnosis and risk stratification of myocardial infarction (MI). Increasing efforts are made to develop additional, new biomarkers for more effective and safe rule-in and rule-out of MI patients at the emergency department. During the past decade, microRNAs (miRNAs) have emerged as new, potential diagnostic biomarkers in several diseases, including MI. In this review, we aimed to summarize some of the prominent studies in the field, and discuss the potential value of miRNAs in the diagnosis of MI. (C) 2016 Elsevier Inc. All rights reserved.

Place, publisher, year, edition, pages
ELSEVIER SCIENCE INC , 2016. Vol. 81, 15-21 p.
Keyword [en]
MicroRNA; Troponin; Biomarker; Acute coronary syndrome
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:liu:diva-129151DOI: 10.1016/j.vph.2016.04.001ISI: 000376054400002PubMedID: 27084396OAI: oai:DiVA.org:liu-129151DiVA: diva2:936055
Note

Funding Agencies|Association for the Promotion of Research in Arteriosclerosis, Thrombosis and Vascular Biology (ATVB); Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria

Available from: 2016-06-13 Created: 2016-06-13 Last updated: 2016-06-13

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