liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
On the Thermodynamics of Smooth Muscle Contraction
Linköping University, Department of Management and Engineering, Solid Mechanics. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0002-9891-6783
Department of Mechanical Engineering & Materials Department, University of California Santa Barbara, CA 93106, USA / School of Engineering, University of Aberdeen, Kings College, Aberdeen, AB24 3UE, UK.
Institute of Biomechanics, Graz University of Technology, Stremayrgasse 16-II, 8010 Graz, Austria / Norwegian University of Science and Technology (NTNU), Faculty of Engineering Science and Technology, 7491 Trondheim, Norway.
2016 (English)In: Journal of the mechanics and physics of solids, ISSN 0022-5096, E-ISSN 1873-4782, Vol. 94, p. 490-503Article in journal (Refereed) Published
Abstract [en]

Cell function is based on many dynamically complex networks of interacting biochemical reactions. Enzymes may increase the rate of only those reactions that are thermodynamically consistent. In this paper we specifically treat the contraction of smooth muscle cells from the continuum thermodynamics point of view by considering them as an open system where matter passes through the cell membrane. We systematically set up a well-known four-state kinetic model for the cross-bridge interaction of actin and myosin in smooth muscle, where the transition between each state is driven by forward and reverse reactions. Chemical, mechanical and energy balance laws are provided in local forms, while energy balance is also formulated in the more convenient temperature form. We derive the local (non-negative) production of entropy from which we deduce the reduced entropy inequality and the constitutive equations for the first Piola-Kirchhoff stress tensor, the heat flux, the ion and molecular flux and the entropy. One example for smooth muscle contraction is analyzed in more detail in order to provide orientation within the established general thermodynamic framework. In particular the stress evolution, heat generation, muscle shorting rate and a condition for muscle cooling is derived.

Place, publisher, year, edition, pages
Pergamon Press, 2016. Vol. 94, p. 490-503
Keywords [en]
Continuum thermodynamics; smooth muscle cell; contraction; kinetic model; constitutive equation; entropy inequality; Gibbs free energy
National Category
Applied Mechanics
Identifiers
URN: urn:nbn:se:liu:diva-129701DOI: 10.1016/j.jmps.2016.05.018ISI: 000382342300027OAI: oai:DiVA.org:liu-129701DiVA, id: diva2:942356
Available from: 2016-06-23 Created: 2016-06-23 Last updated: 2018-01-03

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full text

Authority records

Stålhand, Jonas

Search in DiVA

By author/editor
Stålhand, Jonas
By organisation
Solid MechanicsFaculty of Science & Engineering
In the same journal
Journal of the mechanics and physics of solids
Applied Mechanics

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 79 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf