TY  - CPAPER
TI  - Quantifying the optical properties and chromophore concentrations of turbid media using polarization sensitive hyperspectral imaging : optical phantom studies
J2  - Proceedings Volume 8587, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XI; 85870Z (2013) SPIE BiOS, 2013, San Francisco, California, United States
T2  - SPIE BIOS 2-7 February 2013 San Francisco, California, United States
AU  - Vasefi, Fartash
AU  - Saager, Rolf B.
AU  - Durkin, Anthony J.
AU  - MacKinnon, Nicholas
AU  - Gussakovsky, Eugene
AU  - Chave, Robert
AU  - Farkas, Daniel L.
A2  - aniel L. Farkas, Dan V. Nicolau, and Robert C. Leif
Y1  - 2013///
PY  - 2013
DA  - 2013
KW  - Physical Sciences
KW  - Fysik
VL  - 8587
C7  - 85870Z
PB  - SPIE - International Society for Optical Engineering
DB  - DiVA
DO  - 10.1117/12.2005371
AB  - We present a polarization-sensitive hyperspectral imaging system (SkinSpect) that employs a spectrally-programmable light source in the visible and NIR domains. Multiple tissue-mimicking phantoms were fabricated to mimic the optical properties of normal skin as well as pigmented light and dark moles. The phantoms consist of titanium dioxide and a mixture of coffee, red food dye, and naphthol green as the scattering and the three absorptive agents in a polydimethylsiloxane (PDMS) base. Phantoms were produced with both smooth and rough textured surfaces and tested using Spatial Frequency Domain Imaging (SFDI) and Spatially Modulated Quantitative Spectroscopy (SMoQS) for homogeneity as well as determining absorption and scattering variance, respectively. The reflectance spectral images were also recorded using the SkinSpect research prototype; the spectral signatures of the phantoms were calculated using a two-flux single-layer Kubelka-Munk model and non-negative least square fitting routine was applied to extract the relative concentrations of the individual phantom components. 
LA  - eng
AD  - Spectral Molecular Imaging Inc., USA
AD  - Beckman Laser Institute and Medical Clinic, USA
AD  - Beckman Laser Institute and Medical Clinic, USA
AD  - Spectral Molecular Imaging Inc., USA
AD  - Spectral Molecular Imaging Inc., USA
AD  - Spectral Molecular Imaging Inc., USA
AD  - Spectral Molecular Imaging Inc., USA
Y2  - 2018-11-22T19:43:16.739+01:00
N1  - 2018-12-03T11:42:19.634+01:00
UR  - http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-152327
ER  -