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  • 1.
    Subramaniam, Vimala Devi
    et al.
    CARE, India.
    Prasad, Suhanya Veronica
    CARE, India.
    Banerjee, Antara
    CARE, India.
    Gopinath, Madhumala
    CARE, India.
    Murugesan, Ramachandran
    CARE, India.
    Marotta, Francesco
    Preventit Med Promot Fdn, Peoples R China.
    Sun, Xiao-Feng
    Linköping University, Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Department of Oncology.
    Pathak, Surajit
    CARE, India.
    Health hazards of nanoparticles: understanding the toxicity mechanism of nanosized ZnO in cosmetic products2019In: Drug and chemical toxicology (New York, N.Y. 1978), ISSN 0148-0545, E-ISSN 1525-6014, Vol. 42, no 1, p. 84-93Article, review/survey (Refereed)
    Abstract [en]

    In recent years, nanoparticles are being used extensively in personal healthcare products such as cosmetics, sunscreens, soaps, and shampoos. Particularly, metal oxide nanoparticles are gaining competence as key industrial constituents, progressing toward a remarkable rise in their applications. Zinc oxide and titanium oxide nanoparticles are the most commonly employed metal oxide nanoparticles in sunscreens, ointments, foot care, and over the counter topical products. Dermal exposure to these metal oxides predominantly occurs through explicit use of cosmetic products and airway exposure to nanoparticle dusts is primarily mediated via occupational exposure. There is a compelling need to understand the toxicity effects of nanoparticles which can easily enter the cells and induce oxidative stress. Consequently, these products have become a direct source of pollution in the environment and thereby greatly impact our ecosystem. A complete understanding of the toxicity mechanism of nano-ZnO is intended to resolve whether and to what extent such nanoparticles may pose a threat to the environment and to human beings. In this review article, we have discussed the characteristics of metal oxide nanoparticles and its applications in the cosmetic industry. We have also highlighted about their toxicity effects and their impact on human health.

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