liu.seSearch for publications in DiVA
Change search
Refine search result
1 - 7 of 7
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rows per page
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sort
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
Select
The maximal number of hits you can export is 250. When you want to export more records please use the Create feeds function.
  • 1. Alimov, A
    et al.
    Sundelin, B
    Bergerheim, Ulf
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Division of surgery. Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Urology in Östergötland.
    Pavlenko, M
    Pisa, P
    Zetterberg, A
    Larsson, C
    Lagercrantz, S
    Molecular cytogenetic characterization shows higher genetic homogeneity in conventional renal cell carcinoma compared to other kidney cancers2004In: International Journal of Oncology, ISSN 1019-6439, Vol. 25, p. 955-960Article in journal (Refereed)
  • 2. Alimov, Andrei
    et al.
    Sundelin, Birgitta
    Wang, Naining
    Larsson, Catharina
    Bergerheim, Ulf
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Division of surgery. Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Urology in Östergötland.
    Loss of 14q31-q32.2 in renal cell carcinoma is associated with high malignancy grade and poor survival2004In: International Journal of Oncology, ISSN 1019-6439, Vol. 25, p. 179-185Article in journal (Refereed)
  • 3. Lapointe, Jacques
    et al.
    Li, Chunde
    Higgins, John P
    van de Rijn, Matt
    Bair, Eric
    Montgomery, Kelli
    Ferrari, Michelle
    Egevad, Lars
    Rayford, Walter
    Bergerheim, Ulf
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Division of surgery. Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Urology in Östergötland.
    Ekman, Peter
    DeMarzo, Angelo M
    Tibshirani, Robert
    Botstein, David
    Brown, Patrick O
    Brooks, James D
    Pollack, Jonathan R
    Gene expression profiling identifies clinically relevant subtypes of prostate cancer2004In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 101, no 3, p. 811-816Article in journal (Refereed)
    Abstract [en]

    Prostate cancer, a leading cause of cancer death, displays a broad range of clinical behavior from relatively indolent to aggressive metastatic disease. To explore potential molecular variation underlying this clinical heterogeneity, we profiled gene expression in 62 primary prostate tumors, as well as 41 normal prostate specimens and nine lymph node metastases, using cDNA microarrays containing ≈26,000 genes. Unsupervised hierarchical clustering readily distinguished tumors from normal samples, and further identified three subclasses of prostate tumors based on distinct patterns of gene expression. High-grade and advanced stage tumors, as well as tumors associated with recurrence, were disproportionately represented among two of the three subtypes, one of which also included most lymph node metastases. To further characterize the clinical relevance of tumor subtypes, we evaluated as surrogate markers two genes differentially expressed among tumor subgroups by using immunohistochemistry on tissue microarrays representing an independent set of 225 prostate tumors. Positive staining for MUC1, a gene highly expressed in the subgroups with "aggressive" clinicopathological features, was associated with an elevated risk of recurrence (P = 0.003), whereas strong staining for AZGP1, a gene highly expressed in the other subgroup, was associated with a decreased risk of recurrence (P = 0.0008). In multivariate analysis, MUC1 and AZGP1 staining were strong predictors of tumor recurrence independent of tumor grade, stage, and preoperative prostate-specific antigen levels. Our results suggest that prostate tumors can be usefully classified according to their gene expression patterns, and these tumor subtypes may provide a basis for improved prognostication and treatment stratification.

  • 4. Li, C
    et al.
    Grönberg, H
    Matsuyama, H
    Weber, G
    Nordenskjöld, M
    Naito, K
    Bergh, A
    Bergerheim, Ulf
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Urology. Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Urology in Östergötland.
    Damber, JE
    Larsson, C
    Ekman, P
    Difference between Swedish and Japanese men in the association between AR CAG repeats and prostate cancer suggesting a susceptibility-modifying locus overlapping the androgen receptor gene2003In: International Journal of Molecular Medicine, ISSN 1107-3756, E-ISSN 1791-244X, Vol. 11, p. 529-533Article in journal (Refereed)
  • 5. Matsuyama, H
    et al.
    Pan, Y
    Oba, K
    Tsukamoto, M
    Nagao, K
    Yamaguchi, S
    Fukunaga, K
    Matsuda, K
    Yoshihiro, S
    Li, Ch
    Kudren, D
    Bergerheim, Ulf
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Division of surgery. Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Urology in Östergötland.
    Ekman, P
    Naito, K
    Analysis of genomic alterations on urological malignancies by fluorescence in situ hybridization2003In: Bulletin of the Yamaguchi Medical School, ISSN 0513-1812, Vol. 50, p. 11-18Article in journal (Other academic)
  • 6. Matsuyama, H
    et al.
    Pan, Y
    Oba, K
    Yoshihiro, S
    Matsuda, K
    Hägarth, L
    Kudren, D
    Naito, K
    Bergerheim, Ulf
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Urology. Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Urology in Östergötland.
    Ekman, P
    The role of chromosome 8p22 deletion for predicting disease progression and pathological staging in prostate cancer2003In: Aktuelle Urologie, ISSN 0001-7868, E-ISSN 1438-8820, Vol. 34, p. 247-249Article in journal (Refereed)
  • 7. Matsuyama, Hideyasu
    et al.
    Pan, Yi
    Yoshihiro, Satoru
    Kudren, David
    Naito, Katsusuke
    Bergerheim, Ulf
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Biomedicine and Surgery, Urology. Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Urology in Östergötland.
    Ekman, Peter
    Clinical significance of chromosome 8p, 10q, and 16q deletions in prostate cancer2003In: The Prostate, ISSN 0270-4137, E-ISSN 1097-0045, Vol. 54, p. 103-111Article in journal (Refereed)
1 - 7 of 7
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf