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  • 151.
    Sundström, Simon
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Logopedi, Audiologi och Otorhinolaryngologi. Linköpings universitet, Medicinska fakulteten.
    Prosodic and Phonological Ability in Children with Developmental Language Disorder and Children with Hearing Impairment: In the Context of Word and Nonword Repetition2018Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [en]

    Many children with developmental language disorder (DLD) exhibit difficulties with phonology, i.e. the sounds of language. Children with any degree of hearing impairment (HI) are at an increased risk of problems with spoken language, including phonology. The cause of these difficulties is unknown in children with DLD, and is often assumed to result from reduced hearing acuity in children with HI. Variability in terms of language outcomes is large in both groups, and determining if a child’s language ability is within normal limits or not is problematic. A task that has proven useful in differentiating typical from atypical language development is nonword repetition, in which the child listens to a word form without meaning and repeats it back immediately. Performance in nonword repetition tasks is a potential indicator of language ability in both children with DLD and children with HI. However, it has not been established exactly what the task measures.

    In the present thesis, the ability to repeat prosodic and segmental features of real words and nonwords was investigated in Swedish-speaking four- to six-year-old children with DLD and HI, as well as in children with normal hearing and typical language development (TLD) (papers I, II and III). Further, relations of word and nonword repetition ability to language and hearing were explored (papers II and III), along with comparisons of phonological and grammatical production between the groups (paper IV).

    The findings indicated that the prosodic features stress and tonal word accent affect repetition performance in children with DLD, HI, and TLD. In general, the children with DLD and HI achieved lower results than the children with TLD on repetition of segments (consonants and vowels) and prosodic features, but tonal word accent was repeated with relatively high accuracy. Tonal word accent 1 was more accurately repeated than tonal word accent 2 by the DLD and HI children. The children with TLD repeated tonal word accent with few errors, but segments in nonwords with tonal word accent 2 were easier to repeat than segments in nonwords with tonal word accent 1.

    The results further revealed that the ability of children with DLD to repeat stress in real words is related to expressive grammar, but repetition of prosodic features does not reflect general language knowledge. In contrast, repetition of both segmental and prosodic nonword features may be indicative of receptive vocabulary, phonological production during naming of familiar words, and expressive grammar in children with HI. Repetition performance might be related to the degree of HI before cochlear implantation or fitting of hearing aids.

    Children with DLD and children with HI demonstrate similar strengths and weaknesses in phonological and grammatical production, despite the fact that they develop language under different conditions—with and without normal hearing. Tonal word accent use and syntax are relatively unimpaired in DLD and HI children.

    This thesis highlights prosodic and phonological strengths and weaknesses in children who have, or are at risk of, deficits in language and communication abilities. It also supports word and nonword repetition as potential predictors of some aspects of language ability in children with DLD and HI. Further, it emphasizes the importance of taking prosody into account when constructing, or interpreting results from, repetition tasks. Future research aiming to investigate the relationship between prosody in repetition and language, cognition and hearing, should use longitudinal study designs, and include younger children. Studies comparing prosodic and phonological ability in children with DLD and children with HI should employ both quantitative and qualitative analyses.

    Delarbeten
    1. Repetition of words and non-words in typically developing children: The role of prosody
    Öppna denna publikation i ny flik eller fönster >>Repetition of words and non-words in typically developing children: The role of prosody
    2014 (Engelska)Ingår i: First language, ISSN 0142-7237, E-ISSN 1740-2344, Vol. 34, nr 5, s. 428-449Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    In this study, segmental and prosodic aspects of word repetition and non-word repetition in typically developing children aged four to six years were investigated. Focus was on developmental differences, and on how tonal word accent and word length affect segment production accuracy. Prosodically controlled words and non-words were repeated by 44 Swedish-speaking children. Repetition accuracy for both words and non-words increased with age, and was higher for words than non-words. Further, tonal word accents I and II provided different conditions for segment repetition in favor of accent II during both word repetition and non-word repetition for older children, but only during word repetition for younger children. This suggests age-dependent differences regarding how prosody is stored and integrated with segments. The findings have theoretical significance regarding the role of prosody in the perception, processing and production of phonological information. There are also clinical implications concerning the interpretation of repetition tasks and the potential use of prosody in speech and language intervention.

    Ort, förlag, år, upplaga, sidor
    Sage Publications, 2014
    Nyckelord
    Non-word repetition, phonology, prosody, Swedish, tonal word accent, typical language development, word repetition, Nonordsrepetition, fonologi, prosodi, svenska, ordaccent, typisk språkutveckling, ordrepetition
    Nationell ämneskategori
    Klinisk medicin
    Identifikatorer
    urn:nbn:se:liu:diva-111521 (URN)10.1177/0142723714550213 (DOI)000343246200003 ()
    Tillgänglig från: 2014-10-21 Skapad: 2014-10-21 Senast uppdaterad: 2018-05-15Bibliografiskt granskad
  • 152.
    Sundström, Simon
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Logopedi, Audiologi och Otorhinolaryngologi. Linköpings universitet, Medicinska fakulteten.
    Lofkvist, Ulrika
    Univ Oslo, Norway; Karolinska Inst, Sweden.
    Lyxell, Björn
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Handikappvetenskap. Linköpings universitet, Filosofiska fakulteten. Linköpings universitet, Institutet för handikappvetenskap (IHV).
    Samuelsson, Christina
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Logopedi, Audiologi och Otorhinolaryngologi. Linköpings universitet, Medicinska fakulteten.
    Prosodic and segmental aspects of nonword repetition in 4-to 6-year-old children who are deaf and hard of hearing compared to controls with normal hearing2018Ingår i: Clinical Linguistics & Phonetics, ISSN 0269-9206, E-ISSN 1464-5076, Vol. 32, nr 10, s. 950-971Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Children who are deaf or hard of hearing (DHH) are at an increased risk of speech and language deficits. Nonword repetition (NWR) is a potential predictor of problems with phonology, grammar and lexicon in DHH children. The aim of the present study was to examine repetition of prosodic features and segments in nonwords by DHH children compared to children with normal hearing (NH) and to relate NWR performance to measures of language ability and background variables. In this cross-sectional study, 14 Swedish-speaking children with mild-profound sensorineural hearing loss, aged 4-6 years, and 29 age-matched controls with NH and typical language development participated. The DHH children used cochlear implants (CI), hearing aids or a combination of both. The assessment materials included a prosodically controlled NWR task, as well as tests of phonological production, expressive grammar and receptive vocabulary. The DHH children performed below the children with NH on the repetition of tonal word accents, stress patterns, vowels and consonants, with consonants being hardest, and tonal word accents easiest, to repeat. NWR performance was also correlated with language ability, and to hearing level, in the DHH children. Both prosodic and segmental features of nonwords are problematic for Swedish-speaking DHH children compared to children with NH, but performance on tonal word accent repetition is comparably high. NWR may have potential as a clinically useful tool for identification of children who are in need of speech and language intervention.

  • 153.
    Sundström, Simon
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Logopedi, Audiologi och Otorhinolaryngologi. Linköpings universitet, Medicinska fakulteten.
    Lyxell, Björn
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Handikappvetenskap. Linköpings universitet, Filosofiska fakulteten. Linköpings universitet, Institutet för handikappvetenskap (IHV).
    Samuelsson, Christina
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Logopedi, Audiologi och Otorhinolaryngologi. Linköpings universitet, Medicinska fakulteten.
    Prosodic aspects of repetition in Swedish-speaking children with developmental language disorder2019Ingår i: International Journal of Speech-Language Pathology, ISSN 1754-9507, E-ISSN 1754-9515, Vol. 21, nr 6, s. 623-634Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: To examine repetition of stress and tonal word accents in real words and non-words in Swedish-speaking children with developmental language disorder (DLD), and to investigate the relation of prosodic repetition to measures of language ability.

    Method: A cross-sectional study was undertaken with 30 monolingual Swedish-speaking children with DLD, mean age 4;11 (years;months) and 29 age-matched controls, mean age 5;1, who repeated words and non-words with systematically varying prosody. Group differences for the repetition of prosodic features, and correlations between repetition and phonology, grammar, and vocabulary, were explored.

    Result: Children with DLD performed below controls on repetition of prosodic features of words and non-words. Repetition of stress and tonal word accent was not correlated with phonological production or receptive vocabulary, but a significant correlation was found between stress repetition in words and expressive grammar.

    Conclusion: Repetition of stress and tonal word accents is challenging for children with DLD acquiring Swedish as their first language, but may not be a good indicator of general language ability. Prosody should be taken into account when interpreting results from clinically used word repetition (WR) and non-word repetition (NWR) tasks.

  • 154.
    Sundvall, Erik
    Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan.
    Scalability and Semantic Sustainability in Electronic Health Record Systems2013Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [sv]

    Syftet med denna avhandling är ytterst att göra informationssystem som används i hälso- och sjukvård, särskilt patientjournaler, mer användbara och lättarbetade. Om systemen vore lättare att utveckla och underhålla skulle fler resurser kunna läggas på att tillföra nya och mer användarvänliga funktioner.

    Om journalsystem och datorprogram kan ”begripa” vad olika saker i journalen är och betyder så kan de vara till större hjälp, t.ex. genom att visa bättre patientöversikter och bidra med beslutsstöd. En del i att göra journalinnehållet begripligt och hanterbart för datorer är att använda sig av terminologisystem som t.ex. ICD-10 och SNOMED CT. En annan viktig del är datastrukturerna där man stoppar in text, mätvärden, koderna från terminologisystem etc. De flesta journalsystem har någon sorts mallar som datastrukturer. Projektet openEHR har tagit fram ett sätt att dela specifikationer av datastrukturer mellan olika journalsystem så att man lättare kan dela och återanvända dem och den journaldata som matats in i dem. Dessa specifikationer kallas ”arketyper” och arketyp-metoden beskrivs även i standarden ISO 13606.

    Om två olika journalsystem använder samma datastruktur, t.ex. med hjälp av samma arketyper, så kan de utväxla patientdata mellan varandra (de uppnår s.k. semantisk interoperabilitet). Begreppet ”Semantic sustainability” definieras i avhandlingen som ett förhållningssätt som är bredare än semantisk interoperabilitet. Det syftar till att möjliggöra långsiktigt hållbar utveckling av semantik (betydelse) i journalsystem och genom att hantera risker och resurser förståndigt. Förhållningssättet baserar sig på forskning och erfarenheter från systemutveckling och hantering av komplexa system och är avsett att stödja beslutsfattare, och de som utvecklar och underhåller journalsystem, relaterade system och strukturer.

    För att datorsystem ska kunna växa vid ökad användning ,utan att hamna i återvändsgränder avseende prestanda, så bör vissa designprinciper för skalbarhet följas. Avhandlingen presenterar en systemarkitektur baserad på sådana principer och på arketyp-metoden. Denna arkitektur gör det möjligt att bygga system med delsystem från flera olika leverantörer. Skalbarheten i några lagringslösningar redovisas också.

    Slutligen redovisas prototyper av gränssnitt för patientöversikter och journalläsning.

    Delarbeten
    1. Interactive Visualization and Navigation of Complex Terminology Systems, Exemplified by SNOMED CT
    Öppna denna publikation i ny flik eller fönster >>Interactive Visualization and Navigation of Complex Terminology Systems, Exemplified by SNOMED CT
    2006 (Engelska)Ingår i: Ubiquity: Technologies for Better Health in Aging Societies - Proceedings of MIE2006 / [ed] Arie Hasman, Reinhold Haux, Johan van der Lei, Etienne De Clercq, Francis Roger-France, IOS Press , 2006, s. 851-856Konferensbidrag, Publicerat paper (Refereegranskat)
    Abstract [en]

    Free-text queries are natural entries into the exploration of complex terminology systems. The way search results are presented has impact on the users ability to grasp the overall structure of the system. Complex hierarchies like the one used in SNOMED CT, where nodes have multiple parents (IS-A) and several other relationship types, makes visualization challenging. This paper presents a prototype, Term Viz, applying well known methods like "focus+context" and self-organizing layouts from the fields of Information Visualization and Graph Drawing to terminologies like SNOMED CT and ICD-10. The user can simultaneously focus on several nodes in the terminologies and then use interactive animated graph navigation and semantic zooming to further explore the terminology systems without loosing context. The prototype, based on Open Source Java components, demonstrates how a number of Information Visualisation methods can aid the exploration of medical terminologies with millions of elements and can serve as a base for further development.

    Ort, förlag, år, upplaga, sidor
    IOS Press, 2006
    Serie
    Studies in Health Technology and Informatics, ISSN 0926-9630 ; 124
    Nyckelord
    Terminology, Information Visualization, SNOMED CT, Medical Informatics
    Nationell ämneskategori
    Teknik och teknologier
    Identifikatorer
    urn:nbn:se:liu:diva-38011 (URN)000281143200121 ()17108619 (PubMedID)41106 (Lokalt ID)978-1-58603-647-8 (ISBN)41106 (Arkivnummer)41106 (OAI)
    Konferens
    International Congress of the European Federation for Medical Informatics, 27-30 August 2006, Maastricht, The Netherlands
    Tillgänglig från: 2009-10-10 Skapad: 2009-10-10 Senast uppdaterad: 2013-05-15
    2. Visualizing sets of SNOMED CT concepts to support consistent terminology implementation and reuse of clinical data
    Öppna denna publikation i ny flik eller fönster >>Visualizing sets of SNOMED CT concepts to support consistent terminology implementation and reuse of clinical data
    (Engelska)Manuskript (preprint) (Övrigt vetenskapligt)
    Abstract [en]

    Inconsistent use of concepts is an obstacle when implementing SNOMED CT to improve comparability of information. Terminology implementation should be approached by common strategies for navigating and selecting proper concepts. This study aims to explore ways of illustrating common pathways and ancestors of particular sets of concepts, to support consistent use of SNOMED CT in EHR-system implementation processes. The prototype presented here is an interactive web-based reimplementation of the terminology visualization tool TermViz. The open source prototype contains terminological features that are of relevance when exploring and comparing sets of concepts in SNOMED CT. This includes interactively rearranging graphs, fetching more concept nodes, illustrating least common parents and shared pathways in merged graphs etc. Future work should focus on evaluating the developed prototype in order to assess its applicability in EHR-system-implementation contexts.

    Nyckelord
    Clinical terminology, Implementation, SNOMED CT, Information Visualization
    Nationell ämneskategori
    Systemvetenskap, informationssystem och informatik
    Identifikatorer
    urn:nbn:se:liu:diva-87693 (URN)
    Tillgänglig från: 2013-01-22 Skapad: 2013-01-22 Senast uppdaterad: 2018-01-11
    3. Integration of Tools for Binding Archetypes to SNOMED CT
    Öppna denna publikation i ny flik eller fönster >>Integration of Tools for Binding Archetypes to SNOMED CT
    Visa övriga...
    2008 (Engelska)Ingår i: BMC Medical Informatics and Decision Making, ISSN 1472-6947, E-ISSN 1472-6947, Vol. 8, nr S7Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Background

    The Archetype formalism and the associated Archetype Definition Language have been proposed as an ISO standard for specifying models of components of electronic healthcare records as a means of achieving interoperability between clinical systems. This paper presents an archetype editor with support for manual or semi-automatic creation of bindings between archetypes and terminology systems.

    Methods

    Lexical and semantic methods are applied in order to obtain automatic mapping suggestions. Information visualisation methods are also used to assist the user in exploration and selection of mappings.

    Results

    An integrated tool for archetype authoring, semi-automatic SNOMED CT terminology binding assistance and terminology visualization was created and released as open source.

    Conclusion

    Finding the right terms to bind is a difficult task but the effort to achieve terminology bindings may be reduced with the help of the described approach. The methods and tools presented are general, but here only bindings between SNOMED CT and archetypes based on the openEHR reference model are presented in detail.

    Background

    The Archetype formalism and the associated Archetype Definition Language have been proposed as an ISO standard for specifying models of components of electronic healthcare records as a means of achieving interoperability between clinical systems. This paper presents an archetype editor with support for manual or semi-automatic creation of bindings between archetypes and terminology systems.

    Methods

    Lexical and semantic methods are applied in order to obtain automatic mapping suggestions. Information visualisation methods are also used to assist the user in exploration and selection of mappings.

    Results

    An integrated tool for archetype authoring, semi-automatic SNOMED CT terminology binding assistance and terminology visualization was created and released as open source.

    Conclusion

    Finding the right terms to bind is a difficult task but the effort to achieve terminology bindings may be reduced with the help of the described approach. The methods and tools presented are general, but here only bindings between SNOMED CT and archetypes based on the openEHR reference model are presented in detail.

    Ort, förlag, år, upplaga, sidor
    Springer, 2008
    Nationell ämneskategori
    Medicin och hälsovetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-43812 (URN)10.1186/1472-6947-8-S1-S7 (DOI)000277030600007 ()74857 (Lokalt ID)74857 (Arkivnummer)74857 (OAI)
    Anmärkning

    Original Publication: Erik Sundvall, Rahil Qamar, Mikael Nyström, Mattias Forss, Håkan Petersson, Hans Åhlfeldt and Alan Rector, Integration of Tools for Binding Archetypes to SNOMED CT, 2008, BMC Medical Informatics and Decision Making, (8), S7. http://dx.doi.org/10.1186/1472-6947-8-S1-S7 Licensee: BioMed Central http://www.biomedcentral.com/

    Tillgänglig från: 2009-10-10 Skapad: 2009-10-10 Senast uppdaterad: 2017-12-13
    4. Applying representational state transfer (REST) architecture to archetype-based electronic health record systems
    Öppna denna publikation i ny flik eller fönster >>Applying representational state transfer (REST) architecture to archetype-based electronic health record systems
    Visa övriga...
    2013 (Engelska)Ingår i: BMC Medical Informatics and Decision Making, ISSN 1472-6947, E-ISSN 1472-6947, Vol. 13, nr 57Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Background

    The openEHR project and the closely related ISO 13606 standard have defined structures supporting the content of Electronic Health Records (EHRs). However, there is not yet any finalized openEHR specification of a service interface to aid application developers in creating, accessing, and storing the EHR content.

    The aim of this paper is to explore how the Representational State Transfer (REST) architectural style can be used as a basis for a platform-independent, HTTP-based openEHR service interface. Associated benefits and tradeoffs of such a design are also explored.

    Results

    The main contribution is the formalization of the openEHR storage, retrieval, and version-handling semantics and related services into an implementable HTTP-based service interface. The modular design makes it possible to prototype, test, replicate, distribute, cache, and load-balance the system using ordinary web technology. Other contributions are approaches to query and retrieval of the EHR content that takes caching, logging, and distribution into account. Triggering on EHR change events is also explored.

    A final contribution is an open source openEHR implementation using the above-mentioned approaches to create LiU EEE, an educational EHR environment intended to help newcomers and developers experiment with and learn about the archetype-based EHR approach and enable rapid prototyping.

    Conclusions

    Using REST addressed many architectural concerns in a successful way, but an additional messaging component was needed to address some architectural aspects. Many of our approaches are likely of value to other archetype-based EHR implementations and may contribute to associated service model specifications.

    Ort, förlag, år, upplaga, sidor
    BioMed Central, 2013
    Nationell ämneskategori
    Systemvetenskap, informationssystem och informatik
    Identifikatorer
    urn:nbn:se:liu:diva-87696 (URN)10.1186/1472-6947-13-57 (DOI)000320998000001 ()
    Tillgänglig från: 2013-01-22 Skapad: 2013-01-22 Senast uppdaterad: 2018-01-11
    5. Performance of XML Databases for Epidemiological Queries in Archetype-Based EHRs
    Öppna denna publikation i ny flik eller fönster >>Performance of XML Databases for Epidemiological Queries in Archetype-Based EHRs
    2012 (Engelska)Ingår i: Proceedings Scandinavian Conference on Health Informatics 2012, Linköping: Linköping University Electronic Press, 2012, s. 51-57Konferensbidrag, Publicerat paper (Refereegranskat)
    Abstract [en]

    There are very few published studies regarding the performance of persistence mechanisms for systems that use the openEHR multi level modelling approach. This paper addresses the performance and size of XML databases that store openEHR compliant documents. Database size and response times to epidemiological queries are described. An anonymized relational epidemiology database and associated epidemiological queries were used to generate openEHR XML documents that were stored and queried in four opensource XML databases. The XML databases were considerably slower and required much more space than the relational database. For population-wide epidemiological queries the response times scaled in order of magnitude at the same rate as the number of records (total database size) but were orders of magnitude slower than the original relational database. For individual focused clinical queries where patient ID was specified the response times were acceptable. This study suggests that the tested XML database configurations without further optimizations are not suitable as persistence mechanisms for openEHR-based systems in production if population-wide ad hoc querying is needed.

    Ort, förlag, år, upplaga, sidor
    Linköping: Linköping University Electronic Press, 2012
    Serie
    Linköping Electronic Conference Proceedings, ISSN 1650-3686, E-ISSN 1650-3740 ; 70
    Nyckelord
    Medical Record Systems, Computerized; Database Management Systems, Archetypes, XML Databases, openEHR
    Nationell ämneskategori
    Data- och informationsvetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-84401 (URN)978-91-7519-758-6 (ISBN)
    Konferens
    Scandinavian Conference on Health Informatics 2012, October 2-3, Linköping, Sweden
    Tillgänglig från: 2012-10-05 Skapad: 2012-10-05 Senast uppdaterad: 2018-02-19Bibliografiskt granskad
    6. Approaches to learning openEHR: a qualitative survey, observations, and suggestions
    Öppna denna publikation i ny flik eller fönster >>Approaches to learning openEHR: a qualitative survey, observations, and suggestions
    2016 (Engelska)Ingår i: Proceedings from the 14th Scandinavian Conference on Health Informatics 2016: Gothenburg, Sweden, April 6-7 2016 / [ed] Daniel Karlsson, Andrius Budrionis, Ann Bygholm, Mariann Fossum, Conceicao Granja, Gunnar Hartvigsen, Ole Hejlesen, Maria Hägglund, Monika Alise Johansen, Carl E Moe, Luis Marco-Ruiz, Vivian Vimarlund, Kassaye Y Yigzaw, Linköping: Linköping University Electronic Press, 2016, Vol. 122, s. 29-36Konferensbidrag, Publicerat paper (Refereegranskat)
    Abstract [en]

    Approaches such as ISO 13606 and openEHR aim to address data reusability by defining clinical data structures called archetypes and templates, based on a reference model. A problem with these approaches is that parts of them currently are rather difficult to learn. It can be hard to imagine what an archetype-based clinical system combined with modern terminology systems will look like and what consequences different modeling choices have, without seeing and experimenting with an operational system. This paper reports findings from a survey among openEHR learners and educators combined with observations of related openEHR mailing list discussions. The paper ends with an opinion piece, where we discuss potentially fruitful ways to learn, explore, and extend archetype-based EHR systems using visualization and examples.The findings highlight potential stumble blocks and solutions and should be of interest for both educators and self-learners.

    Ort, förlag, år, upplaga, sidor
    Linköping: Linköping University Electronic Press, 2016
    Serie
    Linköping Electronic Conference Proceedings, ISSN 1650-3686, E-ISSN 1650-3740 ; 122
    Nyckelord
    Electronic Health Records; Software; Learning; Standards
    Nationell ämneskategori
    Systemvetenskap, informationssystem och informatik
    Identifikatorer
    urn:nbn:se:liu:diva-87701 (URN)9789176857762 (ISBN)
    Konferens
    The 14th Scandinavian Conference on Health Informatics 2016, Gothenburg, Sweden, April 6-7 2016
    Tillgänglig från: 2013-01-22 Skapad: 2013-01-22 Senast uppdaterad: 2018-02-05Bibliografiskt granskad
    7. Graphical Overview and Navigation of Electronic Health Records in a prototyping environment using Google Earth and openEHR Archetypes
    Öppna denna publikation i ny flik eller fönster >>Graphical Overview and Navigation of Electronic Health Records in a prototyping environment using Google Earth and openEHR Archetypes
    Visa övriga...
    2007 (Engelska)Ingår i: MEDINFO 2007 - Proceedings of the 12th World Congress on Health (Medical) Informatics – Building Sustainable Health Systems / [ed] Klaus A. Kuhn, James R. Warren, Tze-Yun Leong, IOS Press, 2007, s. 1043-1047Konferensbidrag, Publicerat paper (Refereegranskat)
    Abstract [en]

    This paper describes selected earlier approaches to graphically relating events to each other and to time; some new combinations are also suggested. These are then combined into a unified prototyping environment for visualization and navigation of electronic health records. Google Earth (GE) is used for handling display and interaction of clinical information stored using openEHR data structures and ‘archetypes’. The strength of the approach comes from GE's sophisticated handling of detail levels, from coarse overviews to fine-grained details that has been combined with linear, polar and region-based views of clinical events related to time. The system should be easy to learn since all the visualization styles can use the same navigation.

    The structured and multifaceted approach to handling time that is possible with archetyped openEHR data lends itself well to visualizing and integration with openEHR components is provided in the environment.

    Ort, förlag, år, upplaga, sidor
    IOS Press, 2007
    Serie
    Studies in Health Technology and Informatics, ISSN 0926-9630 ; 129
    Nationell ämneskategori
    Medicin och hälsovetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-38012 (URN)17911874 (PubMedID)41107 (Lokalt ID)978-1-58603-774-1 (ISBN)41107 (Arkivnummer)41107 (OAI)
    Konferens
    12th World Congress on Health (Medical) Informatics – Building Sustainable Health Systems (MEDINFO 2007), 20-24 August 2007, Brisbane, Australia
    Forskningsfinansiär
    EU, FP7, Sjunde ramprogrammet
    Tillgänglig från: 2012-09-27 Skapad: 2009-10-10 Senast uppdaterad: 2015-09-22Bibliografiskt granskad
  • 155.
    Tammimies, Kristiina
    et al.
    Karolinska Inst, Sweden.
    Li, Danyang
    Karolinska Inst, Sweden.
    Rabkina, Ielyzaveta
    Karolinska Inst, Sweden.
    Stamouli, Sofia
    Karolinska Inst, Sweden.
    Becker, Martin
    Karolinska Inst, Sweden.
    Nicolaou, Veronika
    Karolinska Inst, Sweden.
    Berggren, Steve
    Karolinska Inst, Sweden; Stockholm Hlth Serv, Sweden.
    Coco, Christina
    Karolinska Inst, Sweden; Stockholm Hlth Serv, Sweden.
    Falkmer, Torbjörn
    Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för samhällsmedicin. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Sinnescentrum, Smärt och rehabiliteringscentrum. Curtin Univ, Australia.
    Jonsson, Ulf
    Karolinska Inst, Sweden; Stockholm Hlth Serv, Sweden; Uppsala Univ, Sweden.
    Choque-Olsson, Nora
    Karolinska Inst, Sweden.
    Bolte, Sven
    Karolinska Inst, Sweden; Stockholm Hlth Serv, Sweden; Curtin Univ, Australia.
    Association between Copy Number Variation and Response to Social Skills Training in Autism Spectrum Disorder2019Ingår i: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 9, artikel-id 9810Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Challenges in social communication and interaction are core features of autism spectrum disorder (ASD) for which social skills group training (SSGT) is a commonly used intervention. SSGT has shown modest and heterogeneous effects. One of the major genetic risk factors in ASD is rare copy number variation (CNV). However, limited information exists whether CNV profiles could be used to aid intervention decisions. Here, we analyzed the rare genic CNV carrier status for 207 children, of which 105 received SSGT and 102 standard care as part of a randomized clinical trial for SSGT. We found that being a carrier of rare genic CNV did not have an impact on the SSGT outcome measured by the parent-report Social Responsiveness Scale (SRS). However, when stratifying by pathogenicity and size of the CNVs, we identified that carriers of clinically significant and large genic CNVs (amp;gt; 500 kb) showed inferior SRS outcomes at post-intervention (P = 0.047 and P = 0.036, respectively) and follow-up (P = 0.008 and P = 0.072, respectively) when adjusting for standard care effects. Our study provides preliminary evidence that carriers of clinically significant and large genic CNVs might not benefit as much from SSGT as non-carriers. Our results indicate that genetic information might help guide the modifications of interventions in ASD.

  • 156.
    Thammaiah, Spoorthi
    et al.
    Lamar University, TX 77710 USA; Audiol India, India.
    Manchaiah, Vinaya
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Handikappvetenskap. Linköpings universitet, Filosofiska fakulteten. Linköpings universitet, Institutet för handikappvetenskap (IHV). Lamar University, TX 77710 USA; Audiol India, India.
    Easwar, Vijayalakshmi
    Audiol India, India; University of Western Ontario, Canada.
    Krishna, Rajalakshmi
    Audiol India, India; University of Mysore, India.
    McPherson, Bradley
    University of Hong Kong, Peoples R China.
    Psychometric properties of the hearing handicap questionnaire: a Kannada (South-Indian) translation2017Ingår i: International Journal of Audiology, ISSN 1499-2027, E-ISSN 1708-8186, Vol. 56, nr 3, s. 194-201Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: To assess the psychometric properties of the Hearing Handicap Questionnaire (HHQ) in Kannada (a South-Indian language) among adults with hearing loss. Design: The study involved a cross-sectional survey design. Participants provided demographic details and completed the Kannada and English (original) version of the HHQ questionnaire. To evaluate test-retest reliability, approximate to 50% of the participants completed the Kannada version for the second time after 15 days. Study sample: The sample comprised 103 adults with hearing loss recruited from local audiology clinics. Results: Exploratory factor analysis indicated a one-factor structure, which explained 71% of the variance in Kannada-HHQ scores. The internal consistency measured with Cronbachs alpha was 0.96. The test-retest reliability correlations of the Kannada version with the English and with the same Kannada version re-administered after 15 days were 0.96 and 0.91, respectively. Convergent validity of the scale was confirmed by significant correlations with the Participation Scale and the Assessment of Quality of Life scales. Discriminant validity was found to be low as all the Kannada-HHQ questions were highly correlated with each other (ramp;gt;0.60). No floor and ceiling effects were identified. Conclusions: The psychometric properties of the Kannada-HHQ scale are considered to be adequate for clinical or research use.

  • 157.
    Thor, Johan
    et al.
    Högskolan i Jönköping.
    Lundgren, Charlotte
    Linköpings universitet, Institutionen för kultur och kommunikation, Avdelningen för språk och kultur. Linköpings universitet, Institutionen för kultur och kommunikation, Avdelningen för svenska och litteratur. Linköpings universitet, Filosofiska fakulteten.
    Batalden, Paul
    The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth Medical School, Lebanon, New Hampshire, USA.
    Andersson Gäre, Boel
    Landstinget i Jönköpings län.
    Henriks, Göran
    Landstinget i Jönköpings län.
    Sjödahl, Rune
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Kirurgi. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Centrum för kirurgi, ortopedi och cancervård, Kirurgiska kliniken US.
    Gabrielsson Järhult, Felicia
    Högskolan i Jönköping, Institutionen för gerontologi.
    Collaborative improvement of cancer care in southeastern Sweden – striving for better patient and population health, better care, and better professional development2012Ingår i: Sustainably improving health care: creatively linking care outcomes, system performance and professional development / [ed] Batalden, Paul and Foster, Tina, London: Radcliffe Publishing, 2012Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 158.
    Thorslund, Birgitta
    Linköpings universitet, Institutionen för beteendevetenskap och lärande. Linköpings universitet, Filosofiska fakulteten. Linköpings universitet, Institutet för handikappvetenskap (IHV).
    Effects of hearing loss on traffic safety and mobility2014Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [sv]

    Syftet med den här doktorsavhandlingen var att undersöka trafiksäkerhet och mobilitet för individer med hörselnedsättning (HN). Tre studier har genomförts: 1. en enkätstudie för att undersöka skillnader i transportvanor relaterade till HN, 2. en körsimulatorstudie for att titta på kompensatoriska strategier och utvärdera effektiviteten i en taktil signal för att påkalla förarens uppmärksamhet och 3. en fältstudie för att undersöka effekterna i riktig trafik samt utvärdera ett navigationssystem med en taktil signal som stöd för navigering. Effekterna av HN som kom fram i denna avhandling bidrar till kunskapen och förståelsen för hur HN påverkar trafiksäkerhet och mobilitet. De funna skillnaderna pekar konsistent mot ett generelltmera försiktigt beteende. Kompensatoriska - och copingstrategier förknippade med HN beror på körkomplexitet och observeras när komplexiteten ökar. Dessa strategier innebär körning med lägre hastighet, mera heltäckande visuell avsökning och mindre engagemang i distraherande uppgifter. Utvärdering av en taktil signal visade att genom att lägga till en taktil modalitet kan vissa förarstödsystem bli tillgängliga även för förare med HN. Samtidigt kan systemen bli mera effektiva för alla användare eftersom föraren då kan fokusera mera på vägen. Baserat på resultaten i den här avhandlingen kan inte förare med HN betraktas som någon förhöjd risk och det bör därmed inte finnas något behov av att justera hörselkraven när det gäller körkortsinnehav.

    Delarbeten
    1. The Influence of Hearing Loss on Transport Safety and Mobility
    Öppna denna publikation i ny flik eller fönster >>The Influence of Hearing Loss on Transport Safety and Mobility
    2013 (Engelska)Ingår i: European Transport Research Review, ISSN 1867-0717, E-ISSN 1866-8887, Vol. 5, nr 3, s. 117-127Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Purpose

    To examine how road users with different degree of hearing loss experience safety and mobility in transport situations, compared to road users with normal hearing.

    Methods

    A questionnaire study was conducted with participants recruited from the local branch of The Swedish hard of hearing society. A normal hearing control group, matched on age, gender and geographical location, was selected from a commercial database. The response rate was 35 % (n = 194) in the group with Hearing Loss (HL) and 42 % (n = 125) in the group with Normal Hearing (NH). The individuals with hearing loss were grouped into four groups according to the degree of their hearing loss (mild, moderate, severe and profound).

    Results

    Hearing loss affected some specific aspects regarding transport situations, while others remained unaffected. Individuals with hearing loss were not as likely to have a driving license, but for those who have, hearing loss had no effect on mileage per year. Loss of hearing had an effect on criteria for choosing mode of transportation, but in the aggregate, no difference between the groups could be shown in the distribution of how much each mode of transportation was used. With a few exceptions, hearing loss did not affect the ratings of importance of hearing for different transportation modes. Hearing loss affected most questions regarding hearing and driver abilities, while avoidance of specific traffic situations was not associated with hearing loss. Hearing loss had only minor effects on the factors causing inattention when driving, and on the interest in a warning system for driver inattention. The interest in a warning system for driver inattention was high regardless of hearing category.

    Conclusions

    Hearing loss influences the prevalence of driving license and criteria for choosing mode of transportation, however has no effect on the distribution of how much each mode of transportation was used. In general, in this study, respondents with higher degree of hearing loss were less concerned about the effect of hearing loss, indicating that they might be using coping strategies. The interest in warning system for inattention and the attitude towards strengthening of auditory information in traffic situations is high regardless of hearing category. This suggests further research on coping strategies and on design of support systems accessible for drivers with hearing loss.

    Ort, förlag, år, upplaga, sidor
    Springer Berlin/Heidelberg, 2013
    Nyckelord
    Hearing loss, transportation, safety, mobility, support system
    Nationell ämneskategori
    Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
    Identifikatorer
    urn:nbn:se:liu:diva-76697 (URN)10.1007/s12544-012-0087-4 (DOI)000209728100001 ()
    Tillgänglig från: 2012-04-16 Skapad: 2012-04-16 Senast uppdaterad: 2017-06-27Bibliografiskt granskad
    2. Cognitive workload and driving behavior in persons with hearing loss
    Öppna denna publikation i ny flik eller fönster >>Cognitive workload and driving behavior in persons with hearing loss
    2013 (Engelska)Ingår i: Transportation Research Part F: Traffic Psychology and Behaviour, ISSN 1369-8478, E-ISSN 1873-5517, Vol. 21, s. 113-121Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Purpose

    To compare the effect of cognitive workload in individuals with and without hearing loss, respectively, in driving situations with varying degree of complexity.

    Methods

    24 participants with moderate hearing loss (HL) and 24 with normal hearing (NH) experienced three different driving conditions: Baseline driving; Critical events with a need to act fast; and a Parked car event with the possibility to adapt the workload to the situation. Additionally, a Secondary task (observation and recalling of 4 visually displayed letters) was present during the drive, with two levels of difficulty in terms of load on the phonological loop. A tactile signal, presented by means of a vibration in the seat, was used to announce the Secondary task and thereby simultaneously evaluated in terms of effectiveness when calling for driver attention. Objective driver behavior measures (M and SD of driving speed, M and SD of lateral position, time to line crossing) were accompanied by subjective ratings during and after the test drive.

    Results

    HL had no effect on driving behavior at Baseline driving, where no events occurred. Both during Secondary task and at the Parked car event HL was associated with decreased mean driving speed compared to baseline driving. The effect of HL on the Secondary task performance, both at Baseline driving and at the lower Difficulty Level at Critical events, was more skipped letters and fewer correctly recalled letters. At Critical events, task difficulty affected participants with HL more. Participants were generally positive to use vibrations in the seat as a means for announcing the Secondary task.

    Conclusions

    Differences in terms of driving behavior and task performance related to HL appear when the driving complexity exceeds Baseline driving either in the driving task, Secondary task or a combination of both. This leads to a more cautious driving behavior with a decreased mean driving speed and less focus on the Secondary task, which could be a way of compensating for the increasing driving complexity. Seat vibration was found to be a feasible way to alert drivers with or without HL.

    Ort, förlag, år, upplaga, sidor
    Elsevier, 2013
    Nyckelord
    Hearing loss; Cognitive workload; Distraction; Support system
    Nationell ämneskategori
    Samhällsvetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-101198 (URN)10.1016/j.trf.2013.09.011 (DOI)000329413500010 ()
    Tillgänglig från: 2013-11-20 Skapad: 2013-11-20 Senast uppdaterad: 2017-12-06Bibliografiskt granskad
    3. Cognitive workload and visual behavior in elderly drivers with hearing loss
    Öppna denna publikation i ny flik eller fönster >>Cognitive workload and visual behavior in elderly drivers with hearing loss
    Visa övriga...
    2014 (Engelska)Ingår i: European Transport Research Review, ISSN 1867-0717, E-ISSN 1866-8887, Vol. 6, nr 4, s. 377-385Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Purpose

    To examine eye tracking data and compare visual behavior in individuals with normal hearing (NH) and with moderate hearing loss (HL) during two types of driving conditions: normal driving and driving while performing a secondary task.

    Methods

    24 participants with HL and 24 with NH were exposed to normal driving and to driving with a secondary task (observation and recall of 4 visually displayed letters). Eye movement behavior was assessed during normal driving by the following performance indicators: number of glances away from the road; mean duration of glances away from the road; maximum duration of glances away from the road; and percentage of time looking at the road. During driving with the secondary task, eye movement data were assessed in terms of number of glances to the secondary task display, mean duration of glances to the secondary task display, and maximum duration of glances to the secondary task display. The secondary task performance was assessed as well, counting the number of correct letters, the number of skipped letters, and the number of correct letters ignoring order.

    Results

    While driving with the secondary task, drivers with HL looked twice as often in the rear-view mirror than during normal driving and twice as often as drivers with NH regardless of condition. During secondary task, the HL group looked away from the road more frequently but for shorter durations than the NH group. Drivers with HL had fewer correct letters and more skipped letters than drivers with NH.

    Conclusions

    Differences in visual behavior between drivers with NH and with HL are bound to the driving condition. Driving with a secondary task, drivers with HL spend as much time looking away from the road as drivers with NH, however with more frequent and shorter glances away. Secondary task performance is lower for the HL group, suggesting this group is less willing to perform this task. The results also indicate that drivers with HL use fewer but more focused glances away than drivers with NH, they also perform a visual scan of the surrounding traffic environment before looking away towards the secondary task display.

    Ort, förlag, år, upplaga, sidor
    Springer Berlin/Heidelberg, 2014
    Nyckelord
    Hearing loss; Driving simulator; Visual behavior; Cognitive workload
    Nationell ämneskategori
    Tvärvetenskapliga studier inom samhällsvetenskap Övrig annan medicin och hälsovetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-111932 (URN)10.1007/s12544-014-0139-z (DOI)000209729200003 ()2-s2.0-84920249351 (Scopus ID)
    Tillgänglig från: 2014-11-10 Skapad: 2014-11-10 Senast uppdaterad: 2018-01-11Bibliografiskt granskad
    4. Hearing loss and a supportive tactile signal in a navigation system: Effects on driving behavior and eye movements
    Öppna denna publikation i ny flik eller fönster >>Hearing loss and a supportive tactile signal in a navigation system: Effects on driving behavior and eye movements
    Visa övriga...
    2013 (Engelska)Ingår i: Journal of Eye Movement Research, E-ISSN 1995-8692, Vol. 6, nr 5, s. 1-9Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    An on-road study was conducted to evaluate a complementary tactile navigation signal on driving behaviour and eye movements for drivers with hearing loss (HL) compared to drivers with normal hearing (NH). 32 participants (16 HL and16 NH) performed two preprogrammed navigation tasks. In one, participants received only visual information, while the other also included a vibration in the seat to guide them in the correct direction. SMI glasses were used for eye tracking,recording the point of gaze within the scene. Analysis was performed on predefined regions. A questionnaire examined participant's experience of the navigation systems. Hearing loss was associated with lower speed, higher satisfaction with the tactile signal and more glances in the rear view mirror. Additionally, tactile support led to less time spent viewing the navigation display.

    Ort, förlag, år, upplaga, sidor
    INT GROUP EYE MOVEMENT RESEARCH, 2013
    Nyckelord
    hearing loss tactile support navigation system eye movements driving behavior
    Nationell ämneskategori
    Medicinska och farmaceutiska grundvetenskaper
    Identifikatorer
    urn:nbn:se:liu:diva-105369 (URN)10.16910/jemr.6.5.1 (DOI)000339925500001 ()
    Tillgänglig från: 2014-03-19 Skapad: 2014-03-19 Senast uppdaterad: 2018-01-11Bibliografiskt granskad
  • 159.
    Thorslund, Birgitta
    et al.
    Linköpings universitet, Institutionen för beteendevetenskap och lärande. Linköpings universitet, Institutet för handikappvetenskap (IHV). Linköpings universitet, Filosofiska fakulteten.
    Ahlström, Christer
    VTI, Swedish National Road and Transport Research Institute, Linköping, Sweden.
    Peters, Björn
    VTI, Swedish National Road and Transport Research Institute, Linköping, Sweden.
    Eriksson, Olle
    VTI, Swedish National Road and Transport Research Institute, Linköping, Sweden .
    Lidestam, Björn
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Psykologi. Linköpings universitet, Filosofiska fakulteten.
    Lyxell, Björn
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Handikappvetenskap. Linköpings universitet, Filosofiska fakulteten. Linköpings universitet, Institutet för handikappvetenskap (IHV). Östergötlands Läns Landsting, Sinnescentrum, Öron- näsa- och halskliniken US.
    Cognitive workload and visual behavior in elderly drivers with hearing loss2014Ingår i: European Transport Research Review, ISSN 1867-0717, E-ISSN 1866-8887, Vol. 6, nr 4, s. 377-385Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose

    To examine eye tracking data and compare visual behavior in individuals with normal hearing (NH) and with moderate hearing loss (HL) during two types of driving conditions: normal driving and driving while performing a secondary task.

    Methods

    24 participants with HL and 24 with NH were exposed to normal driving and to driving with a secondary task (observation and recall of 4 visually displayed letters). Eye movement behavior was assessed during normal driving by the following performance indicators: number of glances away from the road; mean duration of glances away from the road; maximum duration of glances away from the road; and percentage of time looking at the road. During driving with the secondary task, eye movement data were assessed in terms of number of glances to the secondary task display, mean duration of glances to the secondary task display, and maximum duration of glances to the secondary task display. The secondary task performance was assessed as well, counting the number of correct letters, the number of skipped letters, and the number of correct letters ignoring order.

    Results

    While driving with the secondary task, drivers with HL looked twice as often in the rear-view mirror than during normal driving and twice as often as drivers with NH regardless of condition. During secondary task, the HL group looked away from the road more frequently but for shorter durations than the NH group. Drivers with HL had fewer correct letters and more skipped letters than drivers with NH.

    Conclusions

    Differences in visual behavior between drivers with NH and with HL are bound to the driving condition. Driving with a secondary task, drivers with HL spend as much time looking away from the road as drivers with NH, however with more frequent and shorter glances away. Secondary task performance is lower for the HL group, suggesting this group is less willing to perform this task. The results also indicate that drivers with HL use fewer but more focused glances away than drivers with NH, they also perform a visual scan of the surrounding traffic environment before looking away towards the secondary task display.

  • 160.
    Thörne, Karin
    Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för samhällsmedicin. Linköpings universitet, Medicinska fakulteten.
    Läkare, lärande och interaktion i hälso-och sjukvårdspraktiker2018Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [sv]

    Bakgrund: Komplexiteten i hälso- och sjukvården blir kontinuerligt större, liksom möjligheterna till diagnostik och behandling. Samtidigt pressas hälso- och sjukvården av förändringar i demografier och sjukdomspanoraman, olika uttryck för globalisering och tillämpning av nya teknologier. Ett omfattande antal olika professioner förväntas genomföra och utveckla det dagliga arbetet med ännu mer involvering av patienter. Vi behöver mer kunskap om hur lärande sker och hur det underlättas och utvecklas i dagligt hälso- och sjukvårdsarbete för att kunna möta förändringar och utmaningar.

    Syfte: Avhandlingens övergripande syfte är att fördjupa kunskap och förståelse om pedagogiska processer och lärande i hälso- och sjukvårdspraktiker, med särskilt fokus på läkare.

    Metoder: Intervjustudier och fältstudie med interaktiv forskningsansats gav data med både bredd och djup från autentiskt hälso- och sjukvårdsarbete. I pågående hälso- och sjukvårdsarbete studerades läkare, vårdgivare i andra professioner, patienter, redskap som användes och praktikens rumsliga utformning. Data analyserades genom både kulturella och sociomateriella praktikteoretiska linser, vilket möjliggjorde att flera dimensioner av lärande och interaktion i hälso- och sjukvårdspraktiker kunde spåras.

    Fynd: I arbetet med patienter agerade läkare och andra professioner pedagogiskt med eller utan intentioner, i pedagogiska processer som bestod av att avläsa-färdrikta-lärstödja. Den pedagogiska dimensionen av arbetet var inte synliggjord eller diskuterad i relation till patientarbetet. Dynamiskt inbäddat i arbetet lärde och stöttade läkare också yngre läkares och andra vårdgivares lärande. Läkarnas mobilitet i olika vårdsammanhang, såväl som ansvarsfördelning och delande av olika perspektiv, hade betydelse för vilket lärande som uppstod. Genom att betrakta specifika vårdsammanhang som hälso- och sjukvårdspraktiker under utövning, framträdde vid studiet av en rondmodell både samskapande lärande ronder och operativa ronder med begränsat lärande. Det framträdde genom sättet som deltagande personer, rumsliga och materiella förhållande samspelade på, som ömsesidigt utbyte respektive separata individuella arbetsprocesser. Samspelet mellan hälso- och sjukvårdspraktikers arrangemang (praktikarkitekturer) och genomförande snarare begränsade än underlättade underläkares lärandepraktiker. Underläkarnas arbete hade inte kontinuitet, koherens eller progression för att bredden av kunnande i medicinsk praktiskt arbete skulle kunna utvecklas bra.

    Implikationer: Att förstå och synliggöra lärande i hälso- och sjukvårdens dagliga arbete genom att gemensamt prata om pedagogiska dimensioner i det arbete som pågår, kan utveckla lärande och lärstödjande ageranden. Samskapande lärande hälso- och sjukvårdspraktiker där alla deltagande gruppers behov och uppdrag medräknas, har implikationer på underläkares kompetensutveckling, studenters lärande, patienters involvering i sin vård och interprofessionellt och interdisciplinärt samarbete. Det ger också ledare möjlighet att knyta arbete med förbättringar av vårdens kvalitetet och säkerhet till dagligt vårdarbete.

    Delarbeten
    1. Pedagogical processes in health care: an exploratory study of pedagogic work with patients and next of kin
    Öppna denna publikation i ny flik eller fönster >>Pedagogical processes in health care: an exploratory study of pedagogic work with patients and next of kin
    2009 (Engelska)Ingår i: Education for Health, ISSN 1357-6283, E-ISSN 1469-5804, Vol. 22, nr 3, s. 1-11Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    BACKGROUND: Care and education have much in common, and work in the healthcare sector is closely associated with learning and teaching. It is felt that many in the healthcare and medical services are not aware of their pedagogic skills and how they can be developed. FRAME OF REFERENCE: Belonging to a community of practice means that you share perspectives, methods and language. OBJECTIVE: The aim is to describe the pedagogical discourse by identifying pedagogical processes and studying the staffs awareness of such processes or situations in which a pedagogical approach would be useful in their work with patients and next of kin. METHOD: A qualitative study based on individual and group interviews. The analysis is directed by grounded theory. RESULTS: The pedagogical processes varied in length and quality. Most were unplanned and were usually embedded in treatment. The pedagogical process is linear (planning, goal setting, teaching and evaluating) in an educational setting but we found that the beginning and end can be unclear and the goals can be vague or non-existent. The pedagogical process is best described using the concepts Read, Guide and Provide learning support. DISCUSSION: The pedagogical discourse in healthcare is almost silent. Data indicate that at the collective level there is very little support for professional development of pedagogical ability. Tacit knowledge may therefore remain silent even though it may be possible to formulate and describe it. CONCLUSIONS: There is a strong need to focus on the pedagogical parts of the work and to encourage and support the development of professional pedagogical knowledge.

    Ort, förlag, år, upplaga, sidor
    Carfax Publishing, 2009
    Nationell ämneskategori
    Pedagogik
    Identifikatorer
    urn:nbn:se:liu:diva-56867 (URN)
    Tillgänglig från: 2010-06-08 Skapad: 2010-06-08 Senast uppdaterad: 2018-04-20
    2. The Dynamics of Physicians’ Learning and Support of Others’ Learning
    Öppna denna publikation i ny flik eller fönster >>The Dynamics of Physicians’ Learning and Support of Others’ Learning
    2014 (Engelska)Ingår i: Professions & Professionalism, ISSN 1893-1049, E-ISSN 1893-1049, Vol. 4, nr 1Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Learning has been defined as a condition for improving the quality of healthcare practice. The focus of this paper is on physicians’ learning and their support of others’ learning in the context of Swedish healthcare. Data were generated through individual and focus group interviews and analyzed from a socio-material practice theory perspective. During their workday, physicians dynamically alternated between their own learning and their support of others’ learning in individual patient processes. Learning and learning support were interconnected with the versatile mobility of physicians across different contexts and their participation in multiple communities of collaboration and through tensions between responsibilities in healthcare. The findings illustrate how learning enactments are framed by the existing “practice architectures.” We argue that productive reflection on dimensions of learning enactments in practice can enhance physicians’ professional learning and improve professional practice.

    Ort, förlag, år, upplaga, sidor
    Högskolan Oslo och Akershus, 2014
    Nyckelord
    professional practice; physicians; learning; workplace learning; practice theory; interprofessional learning
    Nationell ämneskategori
    Medicin och hälsovetenskap Samhällsvetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-105998 (URN)10.7577/pp.605 (DOI)
    Tillgänglig från: 2014-04-16 Skapad: 2014-04-16 Senast uppdaterad: 2018-04-20Bibliografiskt granskad
    3. Co-Producing Interprofessional Round Work: Designing Spaces for Patient Partnership
    Öppna denna publikation i ny flik eller fönster >>Co-Producing Interprofessional Round Work: Designing Spaces for Patient Partnership
    2017 (Engelska)Ingår i: Quality Management in Health Care, ISSN 1063-8628, E-ISSN 1550-5154, Vol. 26, nr 2, s. 70-82Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Within wide-ranging quality improvement agendas, patient involvement in health care is widely accepted as crucial. Ward rounds that include patients active participation are growing as an approach to involve patients, ensure safety, and improve quality. An emerging approach to studying quality improvement is to focus on "clinical microsystems," where patients, professionals, and information systems interact. This provides an opportunity to study ward rounds more deeply. A new model of conducting ward rounds implemented through quality improvement work was studied, using the theory of practice architectures as an analytical tool. Practice architecture focuses on the cultural-discursive, social-political, and material-economic conditions that shape what people do in their work. Practice architecture is a sociomaterial theoretical perspective that has the potential to change how we understand relationships between practice, learning, and change. In this study, we examine howchanges in practices are accomplished. The results show that practice architecture formed co-productive learning rounds, a possible model integrating quality improvement in daily work. This emerged in the interplay between patients through their " double participation" (as people and as information on screens), and groups of professionals in a ward round room. However, social interplay had to be renegotiated in order to accomplish the goals of all ward rounds.

    Ort, förlag, år, upplaga, sidor
    LIPPINCOTT WILLIAMS & WILKINS, 2017
    Nyckelord
    clinical microsystem; co-production; practice architectures; sociomaterial practice theory; quality improvement; ward round; workplace learning
    Nationell ämneskategori
    Tvärvetenskapliga studier inom samhällsvetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-137402 (URN)10.1097/QMH.0000000000000133 (DOI)000399390400003 ()28375953 (PubMedID)
    Tillgänglig från: 2017-05-18 Skapad: 2017-05-18 Senast uppdaterad: 2018-04-20
  • 161.
    Tilinca, Mariana Cornelia
    et al.
    Univ Med and Pharm, Romania.
    Barabas-Hajdu, Eniko Csilla
    Univ Med and Pharm, Romania.
    Ferencz, Gizella Tusa
    Region Östergötland, Närsjukvården i västra Östergötland, Medicinska specialistkliniken.
    Nemes-Nagy, Eniko
    Univ Med and Pharm, Romania.
    Involvement of inflammatory cytokines in obesity and its complications2018Ingår i: Revista Romana de Medicina de Laborator, ISSN 1841-6624, Vol. 26, nr 3, s. 359-371Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    n/a

  • 162.
    Topooco, Naira
    et al.
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Psykologi. Linköpings universitet, Filosofiska fakulteten. Ctr m2Hlth, CA USA.
    Bylehn, Sandra
    Linköpings universitet, Institutionen för beteendevetenskap och lärande. Linköpings universitet, Filosofiska fakulteten.
    Dahlström Nysäter, Ellen
    Linköpings universitet, Institutionen för beteendevetenskap och lärande. Linköpings universitet, Filosofiska fakulteten.
    Holmlund, Jenny
    Linköpings universitet, Institutionen för beteendevetenskap och lärande. Linköpings universitet, Filosofiska fakulteten.
    Lindegaard, Johanna
    Linköpings universitet, Institutionen för beteendevetenskap och lärande. Linköpings universitet, Filosofiska fakulteten.
    Johansson, Sanna
    Linköpings universitet, Institutionen för beteendevetenskap och lärande. Linköpings universitet, Filosofiska fakulteten.
    Åberg, Linnea
    Linköpings universitet, Institutionen för beteendevetenskap och lärande. Linköpings universitet, Filosofiska fakulteten.
    Bergman Nordgren, Lise
    Karolinska Inst, Sweden.
    Zetterqvist, Maria
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Centrum för social och affektiv neurovetenskap. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Närsjukvården i centrala Östergötland, Barn- och ungdomspsykiatriska kliniken.
    Andersson, Gerhard
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Psykologi. Linköpings universitet, Filosofiska fakulteten. Karolinska Inst, Sweden.
    Evaluating the Efficacy of Internet-Delivered Cognitive Behavioral Therapy Blended With Synchronous Chat Sessions to Treat Adolescent Depression: Randomized Controlled Trial2019Ingår i: Journal of Medical Internet Research, ISSN 1438-8871, E-ISSN 1438-8871, Vol. 21, nr 11, artikel-id e13393Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Depression is a common and serious problem among adolescents, but few seek or have access to therapy. Internet-delivered cognitive behavioral therapies (ICBTs), developed to increase treatment access, show promise in reducing depression. The inclusion of coach support in treatment is desired and may be needed. Objective: The aim of this study was to determine the efficacy of an ICBT protocol blended with weekly real-time therapist sessions via chat; blended treatment, for adolescent depression, including major depressive episode (MDE). The protocol has previously been evaluated in a controlled study. Methods: In a two-arm randomized controlled trial, adolescents 15 to 19 years of age were recruited through a community setting at the national level in Sweden (n=70) and allocated to either 8 weeks of treatment or to minimal attention control. Depression was assessed at baseline, at posttreatment, and at 12 months following treatment (in the intervention group). The primary outcome was self-reported depression level as measured with the Beck Depression Inventory II at posttreatment. The intervention was offered without the need for parental consent. Results: Over two weeks, 162 adolescents registered and completed the baseline screening. Eligible participants (n=70) were on average 17.5 years of age (SD 1.15), female (96%, 67/70), suffered from MDE (76%, 53/70), had no previous treatment experience (64%, 45/70), and reported guardian(s) to be aware about their depression state (71%, 50/70). The average intervention completion was 74% (11.8 of 16 modules and sessions). Following the treatment, ICBT participants demonstrated a significant decrease in depression symptoms compared with controls (Pamp;lt;.001), corresponding to a large between-group effect (intention-to-treat analysis: d=0.86, 95% CI 0.37-1.35; of completer analysis: d=0.99, 95% CI 0.48-1.51). A significant between-group effect was observed in the secondary depression outcome (P=.003); clinically significant improvement was found in 46% (16/35) of ICBT participants compared with 11% (4/35) in the control group (P=.001). Conclusions: The results are in line with our previous study, further demonstrating that adolescents with depression can successfully be engaged in and experience significant improvement following ICBT blended with therapist chat sessions. Findings on participants age and baseline depression severity are of interest in relation to used study methods.

  • 163.
    Tynngård, Nahreen
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Transfusionsmedicin. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Laboratoriemedicinskt centrum, Klinisk immunologi och transfusionsmedicin.
    Free oscillation rheometry in the assessment of platelet quality2008Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [en]

    Platelets play an important role in the haemostatic process in order to seal damaged blood vessels. The platelets form a platelet plug at the damaged area and prevent blood loss. Once the damage to the vessel wall has been covered, the platelets retract the coagulum, to allow the blood to flow freely in the vessel. Free oscillation rheometry (FOR) can be used for analysis of coagulation as measured by clotting time and changes in clot elasticity (G'). Clot G' provides information about the fibrin network in the coagulum and the platelets’ ability to retract the coagulum. FOR analysis is performed using the ReoRox® 4 instrument. The blood sample is added to a cylindrical sample cup, which is set into free oscillation. The frequency and damping of the oscillation is recorded over time as the blood coagulates. The change in G' is calculated from the frequency and damping measured. Patients with malignant haematological diseases are often thrombocytopaenic and require platelet transfusions to prevent or stop bleeding. To ensure good haemostatic function in the recipient it is important that the quality of the platelets used for transfusion is well preserved. The aim of this thesis was to determine the quality of platelet concentrates (PCs), during storage, using various in vitro methods, including FOR, and to investigate how various preparation processes affect the quality. We also investigated whether FOR can be used to evaluate the haemostatic status in subjects at risk for thrombosis or bleeding as well as how the haemostatic status was affected by a platelet transfusion.

    We show that FOR can provide information about the coagulation properties in subjects at risk of thrombosis (pregnant women) or bleeding (thrombocytopaenic patients). We also show that the coagulation as measured by FOR is influenced by red blood cells and the fibrinogen concentration. However, the presence of functional platelets accounted for 90% of the G'. Furthermore we present data that FOR can provide information on the haemostatic effect of platelet transfusions and on the function of the transfused platelets.

    PCs produced by two different cell separators showed similar quality during storage for 7 days as assessed by FOR analysis. Leukocytes in the PCs can cause transfusion-associated graft-versus-host disease which can be prevented by gamma irradiation of the PCs. Gamma irradiation did not affect the quality of PCs during 7 days of storage as analysed by FOR. The clotting time was unchanged during the storage period. The capacity of platelets to retract the coagulum was reduced from days 1 to 5 of storage as seen by a prolonged time to reach maximum G' and the reduced mean change in G' per minute. However, if sufficient time is allowed for the platelets to regain their function, the clot will be fully retracted (as seen by a well maintained maximum G'). The FOR parameters were similar for 5- and 7-day old PCs, which, combined with other in vitro tests (e.g. hypotonic shock response, changes in pH, swirling, lactate and glucose), support the prolongation of the platelet storage period to 7 days. Intercept treatment of PCs can be performed to inhibit replication of contaminating bacteria in PCs. Intercept treatment of PCs did not diminish the clot-promoting capacity of the platelets as assessed by FOR clotting time.

    In conclusion, FOR is a promising method for assessing hyper- and hypocoagulability. It can provide information on the haemostatic effect of platelet transfusions and the function of the transfused platelets. FOR was also shown to be useful for analysing PC quality during different preparation and storage conditions.

    Delarbeten
    1. Effects of different blood components on clot retraction analysed by measuring elasticity with a free oscillating rheometer
    Öppna denna publikation i ny flik eller fönster >>Effects of different blood components on clot retraction analysed by measuring elasticity with a free oscillating rheometer
    2006 (Engelska)Ingår i: Platelets, ISSN 0953-7104, Vol. 17, nr 8, s. 545-554Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Free oscillation rheometry (FOR) using the ReoRox® 4 instrument makes it possible, at bedside, to study the coagulation process in blood over time and gives information on clotting time and coagulum elastic properties. In order to find out how various factors influence the FOR analysis we studied the coagulation process and change of elasticity over time in non-anticoagulated and citrated blood samples, plasma samples with various platelet concentrations (0-200 109/l) and blood samples with various haematocrit (0-40%). Blood samples supplemented with fibrinogen were analysed to elucidate the importance of fibrinogen on elasticity. The importance of the GPIIb/IIIa receptor on platelets was investigated by comparing the elasticity development in blood samples in presence and absence of a GPIIb/IIIa receptor inhibitor, abciximab. Anticoagulation with citrate did not have major influence on the viscoelastic properties of the coagulum. Increasing number of platelets and increasing fibrinogen concentration resulted in higher elasticity while increasing haematocrit gave lower elasticity. Blood samples with GPIIb/IIIa receptor inhibitor had very low elasticity indicating the importance of functional GPIIb/IIIa receptors. In conclusion we consider FOR to be a useful method to study the elastic properties of the coagulum. Various factors such as the number of red blood cells and platelets as well as the fibrinogen concentration should be taken into consideration when evaluating the results. The ReoRox® 4 instrument had excellent measuring range and unusually small artefactual effects on clot elasticity induced by the instrument in comparison with published results on other instruments.

    Nyckelord
    Coagulation; clot retraction; elasticity; platelets; rheology
    Nationell ämneskategori
    Medicin och hälsovetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-13164 (URN)10.1080/09537100600759238 (DOI)
    Tillgänglig från: 2008-04-14 Skapad: 2008-04-14 Senast uppdaterad: 2020-01-23
    2. Free oscillation rheometry detects changes in clot properties in pregnancy and thrombocytopaenia
    Öppna denna publikation i ny flik eller fönster >>Free oscillation rheometry detects changes in clot properties in pregnancy and thrombocytopaenia
    Visa övriga...
    2008 (Engelska)Ingår i: Platelets, ISSN 0953-7104, Vol. 19, nr 5, s. 373-378Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Improved methods are needed to identify patients at risk for thrombotic or bleeding events. Free oscillation rheometry (FOR) is a technique that offers information on coagulation, based on contributions of all blood components, by measurement of clotting time and changes in clot elasticity. This is the first study that evaluates FOR parameters in subjects likely to represent hypercoagulability (pregnant women) and hypocoagulability (thrombocytopenic patients). Clotting time and blood clot elasticity were measured by FOR in blood samples obtained from women in different pregnancy trimesters (n = 58), in thrombocytopenic patients before and after a platelet transfusion (n = 20) and in healthy blood donors (n = 60). The clotting time was shorter and the clot elasticity higher in pregnant women compared to the non-pregnant female blood donors. The elasticity was higher in late pregnancy compared to early pregnancy. Compared to the blood donors, the thrombocytopenic patients had lower elasticity, which was increased by a platelet transfusion, but there was no difference in clotting time. The results suggest that FOR can provide new information on the haemostatic status of patients at risk of thrombotic or bleeding events as well as information on the haemostatic effect of a platelet transfusion.

    Nyckelord
    Clot elasticity, clot retraction, coagulation, platelets
    Nationell ämneskategori
    Medicin och hälsovetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-13165 (URN)10.1080/09537100802082264 (DOI)
    Tillgänglig från: 2008-04-14 Skapad: 2008-04-14 Senast uppdaterad: 2020-01-23
    3. The quality of platelet concentrates produced by COBE Spectra and Trima Accel during storage for 7 days as assessed by in vitro methods
    Öppna denna publikation i ny flik eller fönster >>The quality of platelet concentrates produced by COBE Spectra and Trima Accel during storage for 7 days as assessed by in vitro methods
    Visa övriga...
    2008 (Engelska)Ingår i: Transfusion, ISSN 0041-1132, E-ISSN 1537-2995, Vol. 48, nr 4, s. 715-722Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Background: The quality of PLT concentrates (PCs) can be evaluated using various in vitro methods. A new technique, free oscillation rheometry (FOR), can be used to monitor coagulation properties of PCs and gives information on clotting time and coagulum elasticity. This study compared the quality of apheresis PCs produced by COBE Spectra and Trima Accel during storage for 7 days using in vitro tests including FOR.

    Study design and methods: Apheresis PCs were collected with the COBE Spectra (n=10) and Trima Accel (n=10) cell separators. Swirling, blood gases and metabolic parameters were analyzed on day 0. Samples taken on day 1, 5 and 7 were also analyzed for hypotonic shock response (HSR), P-selectin and GPIb expression and evaluation of coagulation by FOR.

    Results: Swirling, HSR and percent GPIb expressing PLTs were well maintained for 7 days whereas glucose decreased and lactate increased significantly during storage for both Spectra and Trima PCs. Percent P-selectin expressing cells increased to the same extent in both types of PCs during storage. pH increased between day 0 and 1 but then decreased. The clotting time remained constant throughout the storage period whereas the development of elasticity was reduced on day 5 and 7 compared to day 1 (p<0.05) for both types of PCs.

    Conclusion: The results indicate that the PLT quality after storage for 7 days is well preserved although activation of PLTs occurs during storage as assessed by in vitro tests. No difference in platelet quality was observed between Spectra and Trima produced PCs.

    Nationell ämneskategori
    Medicin och hälsovetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-12533 (URN)10.1111/j.1537-2995.2007.01610.x (DOI)
    Anmärkning
    The definitive version is available at www.blackwell-synergy.com: Nahreen Tynngård, Tomas L. Lindahl, Marie Trinks, Monika Studer and Gösta Berlin, The quality of platelet concentrates produced by COBE Spectra and Trima Accel during storage for 7 days as assessed by in vitro methods, 2008, Transfusion, (48), 4, 715-722. Copyright: Blackwell Publishing www.blackwell-synergy.comTillgänglig från: 2008-09-08 Skapad: 2008-09-12 Senast uppdaterad: 2017-12-08Bibliografiskt granskad
    4. The effect of gamma irradiation on the quality of apheresis platelets during storage for 7 days
    Öppna denna publikation i ny flik eller fönster >>The effect of gamma irradiation on the quality of apheresis platelets during storage for 7 days
    Visa övriga...
    2008 (Engelska)Ingår i: Transfusion, ISSN 0041-1132, E-ISSN 1537-2995, Transfusion, Vol. 48, nr 8, s. 1669-1675Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Background:This study compares the quality of gamma-irradiated versus nonirradiated platelet (PLT) concentrates (PCs) during storage for 7 days as assessed by various in vitro methods. A new technique, free oscillation rheometry (FOR), which measures clotting time and coagulum elasticity, was also used to evaluate the PLT function.

    Study design and methods: Single-donor PLTs were collected by apheresis technique (n = 20). The PLTs from each donor were divided into two PCs, one gamma-irradiated with 25 Gy and the other used as a nonirradiated control. Blood gases, metabolic variables, and swirling were analyzed from Day 0. Samples taken on Days 1, 5, and 7 were also analyzed for hypotonic shock response (HSR), P-selectin, and glycoprotein (GP)Ib expression by flow cytometry and coagulation by FOR.

    Results: Swirling, HSR, and the percentage of GPIb-expressing cells were well maintained for 7 days of storage. pH was always within accepted range (6.4-7.4). Glucose decreased and lactate increased during the storage period (p < 0.05). P-selectin expression increased during storage (p < 0.05). The FOR clotting time remained constant, whereas the build-up of elasticity was slower after storage (p < 0.05). No difference was found between irradiated and nonirradiated PCs.

    Conclusion: The results indicate a well-preserved quality of gamma-irradiated apheresis PLTs during storage for 7 days as assessed by in vitro methods, with no difference compared to nonirradiated PLTs.

    Nationell ämneskategori
    Medicin och hälsovetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-13167 (URN)10.1111/j.1537-2995.2008.01746.x (DOI)
    Tillgänglig från: 2008-04-14 Skapad: 2008-04-14 Senast uppdaterad: 2017-12-13
    5. Effects of intercept pathogen inactivation on platelet function as analysed by free oscillation rheometry
    Öppna denna publikation i ny flik eller fönster >>Effects of intercept pathogen inactivation on platelet function as analysed by free oscillation rheometry
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    2008 (Engelska)Ingår i: Transfusion and apheresis science, ISSN 1473-0502, E-ISSN 1878-1683, Vol. 38, nr 1, s. 85-88Artikel i tidskrift (Refereegranskat) Published
    Abstract [en]

    Introduction: The Intercept Blood System, using InterSol as additive solution, is used for inactivation of contaminating pathogens in PCs, thus reducing the risk for transfusion transmitted infection and making it possible to prolong the storage period. This study aimed at investigating the ability of Intercept treated platelets to induce clot formation, as measured by coagulation time using free oscillation rheometry (FOR), and to compare with that of platelets in concentrates with the additive solution T-Sol or plasma.

    Methods: Seventy-four single-donor platelet units were diluted in InterSol (n = 27) or T-Sol (n = 47) to a mean plasma concentration of 38%. The Intercept treatment was performed by addition of amotosalen HCl to the InterSol PCs followed by UVA irradiation and treatment with a compound adsorption device (CAD). Forty-six units were collected and stored in 100% plasma for comparison. Clotting time was measured by FOR in fresh PCs (within 26 h after collection) after stimulation by a platelet activator. Soluble P-selectin was analysed as a marker of platelet activation in the Intercept and T-Sol PCs.

    Results: The clotting time was shorter for Intercept treated platelets compared to platelets in T-Sol and plasma (p < 0.05). There was no difference in clotting time between T-Sol and plasma PCs. Soluble P-selectin was higher for Intercept platelets than platelets in T-Sol (p < 0.05).

    Conclusions: The platelets treated with the Intercept procedure had good clot promoting capacity.

    Nyckelord
    Apheresis, Pathogen inactivation, Platelet concentrates, Platelet function
    Nationell ämneskategori
    Medicin och hälsovetenskap
    Identifikatorer
    urn:nbn:se:liu:diva-13168 (URN)10.1016/j.transci.2007.12.012 (DOI)
    Tillgänglig från: 2008-04-14 Skapad: 2008-04-14 Senast uppdaterad: 2017-12-13
  • 164.
    von Mentzer, Cecilia Nakeva
    et al.
    Uppsala Univ, Sweden.
    Sundstrom, Martina
    Uppsala Univ, Sweden.
    Enqvist, Karin
    Uppsala Univ, Sweden.
    Hällgren, Mathias
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Logopedi, Audiologi och Otorhinolaryngologi. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Sinnescentrum, Öron- näsa- och halskliniken US.
    Assessing speech perception in Swedish school-aged children: preliminary data on the Listen-Say test2018Ingår i: Logopedics, Phoniatrics, Vocology, ISSN 1401-5439, E-ISSN 1651-2022, Vol. 43, nr 3, s. 106-119Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    To meet the need for a linguistic speech perception test in Swedish, the Listen-Say test was developed. Minimal word pairs were used as speech material to assess seven phonetic contrasts in two auditory backgrounds. In the present study, childrens speech discrimination skills in quiet and in four-talker (4T) speech background were examined. Associations with lexical-access skills and academic achievement were explored. The study included 27 school children 7-9 years of age. Overall, the children discriminated phonetic contrasts well in both conditions (quiet: Mdn 95%; 4T speech; Mdn 91% correct). A significant effect of 4T speech background was evident in three of the contrasts, connected to place of articulation, voicing and syllable complexity. Reaction times for correctly identified target words were significantly longer in the quiet condition, possibly reflecting a need for further balancing of the test order. Overall speech discrimination accuracy was moderately to highly correlated with lexical-access ability. Children identified as having high concentration ability by their teacher had the highest speech discrimination scores in both conditions followed by children identified as having high reading ability. The first wave of data collection with the Listen-Say test indicates that the test appears to be sensitive to predicted perceptual difficulties of phonetic contrasts particularly in noise. The clinical benefit of using a procedure where speech discrimination, lexical-access ability and academic achievement are taken into account is discussed as well as issues for further test refinement.

  • 165.
    Waldreus, Nana
    et al.
    Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Sweden.
    Jaarsma, Tiny
    Linköpings universitet, Institutionen för samhälls- och välfärdsstudier, Avdelningen för omvårdnad. Linköpings universitet, Medicinska fakulteten. Mary McKillop Institute for Health Research, Catholic University of Australia, Australia.
    van der Wal, Martje
    Linköpings universitet, Medicinska fakulteten. Linköpings universitet, Institutionen för samhälls- och välfärdsstudier, Avdelningen för omvårdnad. Department of Cardiology, University of Groningen, Groningen, The Netherlands.
    Perkiö Kato, Naoko
    Linköpings universitet, Institutionen för samhälls- och välfärdsstudier, Avdelningen för omvårdnad. Linköpings universitet, Medicinska fakulteten. Department of Therapeutic Strategy for Heart Failure, The University of Tokyo Graduate School of Medicine, Japan.
    Development and psychometric evaluation of the Thirst Distress Scale for patients with heart failure2018Ingår i: European Journal of Cardiovascular Nursing, ISSN 1474-5151, E-ISSN 1873-1953, Vol. 17, nr 3, s. 226-234Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background:

    Patients with heart failure can experience thirst distress. However, there is no instrument to measure this in patients with heart failure. The aim of the present study was to develop the Thirst Distress Scale for patients with Heart Failure (TDS-HF) and to evaluate psychometric properties of the scale.

    Methods and results:

    The TDS-HF was developed to measure thirst distress in patients with heart failure. Face and content validity was confirmed using expert panels including patients and healthcare professionals. Data on the TDS-HF was collected from patients with heart failure at outpatient heart failure clinics and hospitals in Sweden, the Netherlands and Japan. Psychometric properties were evaluated using data from 256 heart failure patients (age 72±11 years). Concurrent validity of the scale was assessed using a thirst intensity visual analogue scale. Patients did not have any difficulties answering the questions, and time taken to answer the questions was about five minutes. Factor analysis of the scale showed one factor. After psychometric testing, one item was deleted. For the eight item TDS-HF, a single factor explained 61% of the variance and Cronbach’s alpha was 0.90. The eight item TDS-HF was significantly associated with the thirst intensity score (r=0.55, p<0.001). Regarding test-retest reliability, the intraclass correlation coefficient was 0.88, and the weighted kappa values ranged from 0.29–0.60.

    Conclusion:

    The eight-item TDS-HF is valid and reliable for measuring thirst distress in patients with heart failure.

  • 166.
    Wang, Yang
    et al.
    Vrije Univ Amsterdam, Netherlands; Amsterdam Publ Hlth Res Inst, Netherlands; Oticon AS, Denmark.
    Naylor, Graham
    MRC, Scotland.
    Kramer, Sophia E.
    Vrije Univ Amsterdam, Netherlands; Amsterdam Publ Hlth Res Inst, Netherlands.
    Zekveld, Adriana
    Linköpings universitet, Institutionen för beteendevetenskap och lärande. Linköpings universitet, Institutet för handikappvetenskap (IHV). Linköpings universitet, Filosofiska fakulteten. Vrije Univ Amsterdam, Netherlands; Amsterdam Publ Hlth Res Inst, Netherlands.
    Wendt, Dorothea
    Oticon AS, Denmark; Tech Univ Denmark, Denmark.
    Ohlenforst, Barbara
    Vrije Univ Amsterdam, Netherlands; Amsterdam Publ Hlth Res Inst, Netherlands; Oticon AS, Denmark.
    Lunner, Thomas
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Handikappvetenskap. Linköpings universitet, Filosofiska fakulteten. Linköpings universitet, Institutet för handikappvetenskap (IHV). Oticon AS, Denmark; Tech Univ Denmark, Denmark.
    Relations Between Self-Reported Daily-Life Fatigue, Hearing Status, and Pupil Dilation During a Speech Perception in Noise Task2018Ingår i: Ear and Hearing, ISSN 0196-0202, E-ISSN 1538-4667, Vol. 39, nr 3, s. 573-582Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: People with hearing impairment are likely to experience higher levels of fatigue because of effortful listening in daily communication. This hearing-related fatigue might not only constrain their work performance but also result in withdrawal from major social roles. Therefore, it is important to understand the relationships between fatigue, listening effort, and hearing impairment by examining the evidence from both subjective and objective measurements. The aim of the present study was to investigate these relationships by assessing subjectively measured daily-life fatigue (self-report questionnaires) and objectively measured listening effort (pupillometry) in both normally hearing and hearing-impaired participants. Design: Twenty-seven normally hearing and 19 age-matched participants with hearing impairment were included in this study. Two self-report fatigue questionnaires Need For Recovery and Checklist Individual Strength were given to the participants before the test session to evaluate the subjectively measured daily fatigue. Participants were asked to perform a speech reception threshold test with single-talker masker targeting a 50% correct response criterion. The pupil diameter was recorded during the speech processing, and we used peak pupil dilation (PPD) as the main outcome measure of the pupillometry. Results: No correlation was found between subjectively measured fatigue and hearing acuity, nor was a group difference found between the normally hearing and the hearing-impaired participants on the fatigue scores. A significant negative correlation was found between self-reported fatigue and PPD. A similar correlation was also found between Speech Intelligibility Index required for 50% correct and PPD. Multiple regression analysis showed that factors representing "hearing acuity" and "self-reported fatigue" had equal and independent associations with the PPD during the speech in noise test. Less fatigue and better hearing acuity were associated with a larger pupil dilation. Conclusions: To the best of our knowledge, this is the first study to investigate the relationship between a subjective measure of daily-life fatigue and an objective measure of pupil dilation, as an indicator of listening effort. These findings help to provide an empirical link between pupil responses, as observed in the laboratory, and daily-life fatigue.

  • 167.
    Wedin, Madelene
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för barns och kvinnors hälsa. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Barn- och kvinnocentrum, Kvinnokliniken i Linköping.
    Fredrikson, Mats
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för neuro- och inflammationsvetenskap. Linköpings universitet, Medicinska fakulteten.
    Ahlner, Eva
    Linköpings universitet, Institutionen för klinisk och experimentell medicin. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Centrum för kirurgi, ortopedi och cancervård, Onkologiska kliniken US.
    Falk, Annika
    Norrlands Univ Hosp, Sweden.
    Sandstrom, Asa
    Norrlands Univ Hosp, Sweden.
    Lindahl, Gabriel
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Kirurgi, Ortopedi och Onkologi. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Centrum för kirurgi, ortopedi och cancervård, Onkologiska kliniken US.
    Rosenberg, Per
    Linköpings universitet, Institutionen för klinisk och experimentell medicin. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Centrum för kirurgi, ortopedi och cancervård, Onkologiska kliniken US.
    Kjölhede, Preben
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för barns och kvinnors hälsa. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Barn- och kvinnocentrum, Kvinnokliniken i Linköping.
    Validation of the Lymphoedema Quality of Life Questionnaire (LYMQOL) in Swedish cancer patients2020Ingår i: Acta Oncologica, ISSN 0284-186X, E-ISSN 1651-226XArtikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: The aim of this study was to validate a translated Swedish version of the lymphoedema-specific quality of life questionnaire (LYMQOL) in a cohort of Swedish cancer patients with secondary lymphoedema of the limbs after cancer treatment.

    Material and methods: We recruited 102 patients with lymphoedema of the arms or legs after cancer treatment who were visiting lymphoedema therapists at the departments of oncology at the university hospitals in Linköping and Umeå. The LYMQOL questionnaires were translated forward and backward from English to Swedish. Content and face validity were evaluated. The construct validity was assessed by comparing the LYMQOL with the Short Form Health Survey (SF-36) and the perceived degree of lymphoedema of the limbs, respectively. Reliability was determined through test-retest. The internal consistency was assessed by determining Cronbach’s alpha and by factor analysis.

    Results: The content and face validity assessments showed that LYMQOL was an easy, clear and not too long questionnaire to use for patients with lymphoedema. Construct validity was high in both versions when compared with the SF-36. The association between the degrees of perceived lymphoedema and the LYMQOL was only significant in the domains Function and Body Image in the arm version, whereas all domains in the leg version were significant. The reliability was good for the arm version (intra-class-correlation coefficients 0.53–0.87) and very good for the leg version (intra-class-correlation coefficients 0.78–0.90). The internal consistency was acceptable to excellent, with Cronbach’s alpha values between 0.79–0.93 (arm-version) and 0.87–0.94 (leg-version). The factor analysis confirmed the usefulness of the four domains in the LYMQOL versions.

    Conclusions: This study confirmed the validity of the Swedish version of LYMQOL and demonstrated that LYMQOL may be a simple and useful tool for use in clinical practice and scientific contexts for evaluating QoL in patients with lymphoedema of the limbs.

  • 168.
    Wissel, Joerg
    et al.
    Vivantes Klinikum Spandau, Germany.
    Ganapathy, Vaidyanathan
    Sunovion Pharmaceut Inc, MA USA.
    Ward, Anthony B.
    Haywood Hospital, England.
    Borg, Jorgen
    Danderyd Hospital, Sweden.
    Ertzgaard, Per
    Linköpings universitet, Medicinska fakulteten. Region Östergötland, Sinnescentrum, Rehabiliteringsmedicinska kliniken. Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för samhällsmedicin.
    Herrmann, Christoph
    Asklepios Kliniken Schildautal, Germany.
    Häggstrom, Anders
    Örebro University Hospital, Sweden.
    Sakel, Mohamed
    East Kent University Hospital NHS, England.
    Ma, Julia
    Allergan Plc, CA 92612 USA.
    Dimitrova, Rozalina
    Allergan Plc, CA 92612 USA.
    Fulford-Smith, Antony
    Marlow Int, England.
    Gillard, Patrick
    Allergan Plc, CA 92612 USA.
    OnabotulinumtoxinA Improves Pain in Patients With Post-Stroke Spasticity: Findings From a Randomized, Double-Blind, Placebo-Controlled Trial2016Ingår i: Journal of Pain and Symptom Management, ISSN 0885-3924, E-ISSN 1873-6513, Vol. 52, nr 1, s. 17-26Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Context. Patients with post-stroke spasticity (PSS) commonly experience pain in affected limbs, which may impact quality of life. Objectives. To assess onabotulinumtoxinA for pain in patients with PSS from the BOTOX (R) Economic Spasticity Trial, a multicenter, randomized, double-blind, placebo-controlled trial. Methods. Patients with PSS (N = 273) were randomized to 22- to 34-week double-blind treatment with onabotulinumtoxinA + standard care (SC) or placebo injection + SC and were eligible to receive open-label onabotulinumtoxinA up to 52 weeks. Assessments included change from baseline on the 11-point pain numeric rating scale, proportion of patients with baseline pain amp;gt;= 4 achieving amp;gt;= 30% and amp;gt;= 50% improvement in pain, and pain interference with work at Week 12, end of double-blind treatment, and Week 52. Results. At baseline, most patients (74.3%) experienced pain and 47.4% had pain amp;gt;= 4 (pain subgroup). Mean pain reduction from baseline at Week 12 was significantly greater with onabotulinumtoxinA + SC (-0.77, 95% CI -1.14 to -0.40) than placebo + SC (-0.13, 95% CI -0.51 to 0.24; P amp;lt; 0.05). Higher proportions of patients in the pain subgroup achieved amp;gt;= 30% and amp;gt;= 50% reductions in pain at Week 12 with onabotulinumtoxinA + SC (53.7% and 37.0%, respectively) compared with placebo (28.8% and 18.6%, respectively; P amp;lt; 0.05). Reductions in pain were sustained through Week 52. Compared with placebo + SC, onabotulinumtoxinA consistently reduced pain interference with work. Conclusion. This is the first randomized, placebo-controlled trial demonstrating statistically significant and clinically meaningful reductions in pain and pain interference with work with onabotulinumtoxinA in patients with PSS. (C) 2016 The Authors. Published by Elsevier Inc. on behalf of American Academy of Hospice and Palliative Medicine. This is an open access article under the CC BY-NC-ND license.

  • 169.
    Zamengo, Luca
    et al.
    AULSS 3, Italy.
    Tedeschi, Gianpaola
    AULSS 3, Italy.
    Frison, Giampietro
    AULSS 3, Italy.
    Griffoni, Carlo
    Veneto Eye Bank Fdn, Italy.
    Ponzin, Diego
    Veneto Eye Bank Fdn, Italy.
    Jones, A Wayne
    Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för läkemedelsforskning. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Diagnostikcentrum, Klinisk farmakologi.
    Inter-laboratory proficiency results of blood alcohol determinations at clinical and forensic laboratories in Italy2019Ingår i: Forensic Science International, ISSN 0379-0738, E-ISSN 1872-6283, Vol. 295, s. 213-218Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Inter-laboratory proficiency schemes are widely used to control the performance of clinical and forensic toxicology laboratories. In 2016 the Laboratory of Environmental Hygiene and Forensic Toxicology - Venice (Italy) initiated an inter-laboratory proficiency test of blood-alcohol analysis. The number of participating laboratories gradually increased from 26 to 36. Furthermore, a few clinical laboratories were included if gas chromatographic (GC) methods were used for blood alcohol analysis. Procedure: Whole blood was obtained from the Blood Transfusion Centre of the Venice Hospital and a mixture of sodium fluoride and potassium oxalate was added as a preservative and anticoagulant, respectively. Aliquots of the blood were spiked with certified pure ethanol to obtain target blood-alcohol concentrations (BACs) ranging from 0 to 5.0 g/L. Two blood samples (4 mL each) were included in each shipment to the participating laboratories. The laboratories were asked to provide information about number of replicate BAC determinations they made, the types of ethanol reference standards used, and inherent measurement uncertainty. The aim of the testing was to obtain a mean consensus value for the target BAC and to assess inter-laboratory imprecision. All procedures for registration and submission of results were done on-line. A confidential report and statistical evaluations were returned to the participants one week later. Analytical methods: All participants used head-space GC (HS-GC) for the analysis of ethanol in blood. More than 85% of participants used HS-GC with flame-ionization detection, whereas the others used mass spectrometry (MS) as a detector. More than 40% of the participating laboratories kept the blood samples frozen (-20 degrees C) prior to analysis, whereas the others used refrigeration (+4 degrees C). The preliminary validation tests showed that there were no statistically significant differences between BAC in frozen or refrigerated samples for a period of 20 days. Results and conclusion: The statistical evaluation of results was done using an iterative procedure known as Algorithm A (ISO 13528:2015, C.3.1). This provides robust estimates for mean and standard deviation between laboratories and these were used as consensus values. More than 85% of participants provided satisfactory results (z-score amp;lt;1) and 94% of laboratories were within z-score amp;lt;2, based on five control samples. When a blood sample without any alcohol (blank) was sent for analysis, laboratories reported this as zero, 0.00 g/L, below limit of detection (LOD) or not detected. Some type of consensus should be reached for reporting blank samples. (C) 2018 Elsevier B.V. All rights reserved.

  • 170.
    Zekveld, Adriana
    et al.
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Handikappvetenskap. Linköpings universitet, Filosofiska fakulteten. Linköpings universitet, Institutet för handikappvetenskap (IHV). Vrije Univ Amsterdam, Netherlands.
    Kramer, Sophia E.
    Section Ear & Hearing, Department of Otolaryngology-Head and Neck Surgery and Amsterdam Public Health research institute VU University Medical Center, Amsterdam, The Netherlands.
    Rönnberg, Jerker
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Handikappvetenskap. Linköpings universitet, Filosofiska fakulteten. Linköpings universitet, Institutet för handikappvetenskap (IHV).
    Rudner, Mary
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Handikappvetenskap. Linköpings universitet, Filosofiska fakulteten. Linköpings universitet, Institutet för handikappvetenskap (IHV).
    In a Concurrent Memory and Auditory Perception Task, the Pupil Dilation Response Is More Sensitive to Memory Load Than to Auditory Stimulus Characteristics2019Ingår i: Ear and Hearing, ISSN 0196-0202, E-ISSN 1538-4667, Vol. 40, nr 2, s. 272-286Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objectives: Speech understanding may be cognitively demanding, but it can be enhanced when semantically related text cues precede auditory sentences. The present study aimed to determine whether (a) providing text cues reduces pupil dilation, a measure of cognitive load, during listening to sentences, (b) repeating the sentences aloud affects recall accuracy and pupil dilation during recall of cue words, and (c) semantic relatedness between cues and sentences affects recall accuracy and pupil dilation during recall of cue words.

    Design: Sentence repetition following text cues and recall of the text cues were tested. Twenty-six participants (mean age, 22 years) with normal hearing listened to masked sentences. On each trial, a set of four-word cues was presented visually as text preceding the auditory presentation of a sentence whose meaning was either related or unrelated to the cues. On each trial, participants first read the cue words, then listened to a sentence. Following this they spoke aloud either the cue words or the sentence, according to instruction, and finally on all trials orally recalled the cues. Peak pupil dilation was measured throughout listening and recall on each trial. Additionally, participants completed a test measuring the ability to perceive degraded verbal text information and three working memory tests (a reading span test, a size-comparison span test, and a test of memory updating).

    Results: Cue words that were semantically related to the sentence facilitated sentence repetition but did not reduce pupil dilation. Recall was poorer and there were more intrusion errors when the cue words were related to the sentences. Recall was also poorer when sentences were repeated aloud. Both behavioral effects were associated with greater pupil dilation. Larger reading span capacity and smaller size-comparison span were associated with larger peak pupil dilation during listening. Furthermore, larger reading span and greater memory updating ability were both associated with better cue recall overall.

    Conclusions: Although sentence-related word cues facilitate sentence repetition, our results indicate that they do not reduce cognitive load during listening in noise with a concurrent memory load. As expected, higher working memory capacity was associated with better recall of the cues. Unexpectedly, however, semantic relatedness with the sentence reduced word cue recall accuracy and increased intrusion errors, suggesting an effect of semantic confusion. Further, speaking the sentence aloud also reduced word cue recall accuracy, probably due to articulatory suppression. Importantly, imposing a memory load during listening to sentences resulted in the absence of formerly established strong effects of speech intelligibility on the pupil dilation response. This nullified intelligibility effect demonstrates that the pupil dilation response to a cognitive (memory) task can completely overshadow the effect of perceptual factors on the pupil dilation response. This highlights the importance of taking cognitive task load into account during auditory testing.

  • 171.
    Öberg, Marie
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för neuro- och inflammationsvetenskap. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Sinnescentrum, Öron- näsa- och halskliniken US.
    A multicentre study evaluating the effects of the Swedish ACE programme2017Ingår i: International Journal of Audiology, ISSN 1499-2027, E-ISSN 1708-8186, Vol. 56, nr 11, s. 876-886Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: This study investigated the effects of a modified Swedish version of an interactive group education programme, the Active Communication Education (ACE) programme, in five Swedish regions. This study also explored whether the pre- and post-programme outcomes differed with regard to region, age, gender, hearing loss (HL) or the attendance of significant others (SOs). Design: An intervention study with between- and within-group measurements was applied. Study sample: Seventy-seven individuals with hearing impairments and a mean age of 73.9 years (SD = 9.8) from five different regions in Sweden participated in this study. Results: Statistically significant short- and long-term effects on communication strategy use, activity and participation were observed. The ACE programme was most effective for older individuals, women and participants with more severe HL. Individuals who attended with an SO tended to use better communication strategies. No regional differences were observed. The qualitative results indicated that the programme increased individuals ability to cope and restored their social identities. Conclusions: The ACE programme is effective, is recommended for implementation in clinical settings and is considered an alternative or additional treatment to hearing aid rehabilitation. Additional studies that include younger individuals and a control group are recommended.

  • 172.
    Öberg, Marie
    Region Östergötland, Sinnescentrum, Öron- näsa- och halskliniken US. Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för neuro- och inflammationsvetenskap. Linköpings universitet, Medicinska fakulteten.
    Amulticenter study evaluating the effects of the Swedish ACE programme2017Konferensbidrag (Övrigt vetenskapligt)
  • 173.
    Öberg, Marie
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Region Östergötland, Sinnescentrum, Öron- näsa- och halskliniken US. Linköpings universitet, Medicinska fakulteten.
    Arlinger, Stig
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för neuro- och inflammationsvetenskap. Linköpings universitet, Medicinska fakulteten.
    Nordqvist, Peter
    3. Dept. of Speech, Music and Hearing School of Computer Science and Communication KTH - Royal Institute of.
    Swedish quality register of hearing aid rehabilitation – Results from a large data set2016Ingår i: Swedish quality register of hearing aid rehabilitation – Results from a large data set, 2016Konferensbidrag (Refereegranskat)
    Abstract [en]

    Abstract:

    Purpose

    The aim of the study is to present normative data of hearing aid rehabilitation for a Swedish population with regard to gender, age, return

    clients/first time user and bilateral/unilateral hearing aid use.

    Method

    Questionnaires with 19 items were sent by mail to clients 3-6 months after completed hearing aid rehabilitation. In addition to the seven IOI-HA

    items there were five items concerning satisfaction with reception, information and participation and seven items concerning functionality with the

    hearing aids.

    Results

    Approximately 60 000 hearing aid users returned the questionnaire during the period 2011-2014 (response rate 52.5%). Differences were found

    with regard to hearing aid experiences, gender and unilateral versus bilateral hearing aid fitting. Women compared to men and bilaterally fitted

    compared to unilaterally fitted, reported significantly higher scores for all seven items in IOI-HA. The largest differences in mean score were found

    for the item hearing aid use between experienced and first-time user where experienced users used the aids more. No correlation was found

    between mean IOI-HA score and average hearing threshold level.

    Conclusion

    When evaluating hearing aid rehabilitation differences between groups need to be considered.

  • 174.
    Öberg, Marie
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för neuro- och inflammationsvetenskap. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Sinnescentrum, Öron- näsa- och halskliniken US.
    Elisabet, Sundewall Thorén
    Eriksholm Reserach Centre, Denmark.
    Hagejärd, Lena
    Avdelningen för logopedi, foniatri och audiologi, Lunds universitet, Lund Sverige.
    Teodorescu, Ina
    Avdelningen för logopedi, foniatri och audiologi, Lunds universitet, Lund Sverige.
    Online Individualized Active Communication Education- a Swedish pilot study2015Konferensbidrag (Övrigt vetenskapligt)
  • 175.
    Öberg, Marie
    et al.
    Region Östergötland, Sinnescentrum, Öron- näsa- och halskliniken US. Linköpings universitet, Medicinska fakulteten.
    Ingo, Elisabet
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Handikappvetenskap. Linköpings universitet, Filosofiska fakulteten.
    On-line supportsystem för audionomer och förstagångsbrukare2017Konferensbidrag (Övrigt vetenskapligt)
  • 176.
    Öberg, Marie
    et al.
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för neuro- och inflammationsvetenskap. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Sinnescentrum, Öron- näsa- och halskliniken US.
    Wänström, Gunilla
    Region Östergötland, Sinnescentrum, Öron- näsa- och halskliniken US.
    Andersson, Gerhard
    Linköpings universitet, Institutionen för beteendevetenskap och lärande, Psykologi. Linköpings universitet, Filosofiska fakulteten.
    Lunner, Thomas
    Eriksholm Research Centre, Denmark.
    Behandlingsprocessens betydelse vid hörapparatanpassning2015Konferensbidrag (Övrigt vetenskapligt)
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