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  • 301.
    Akin, H. Levent
    et al.
    Bogazici University, Turkey.
    Ito, Nobuhiro
    Aichi Institute of Technology, Japan.
    Jacoff, Adam
    National Institute of Standards, USA.
    Kleiner, Alexander
    Linköpings universitet, Institutionen för datavetenskap, Artificiell intelligens och integrerade datorsystem. Linköpings universitet, Tekniska högskolan.
    Pellenz, Johannes
    V&R Vision & Robotics GmbH, Germany.
    Visser, Arnoud
    University of Amsterdam, Holland.
    RoboCup Rescue Robot and Simulation Leagues2013Ingår i: The AI Magazine, ISSN 0738-4602, Vol. 34, nr 1Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The RoboCup Rescue Robot and Simulation competitions have been held since 2000. The experience gained during these competitions has increased the maturity level of the field, which allowed deploying robots after real disasters (e.g. Fukushima Daiichi nuclear disaster). This article provides an overview of these competitions and highlights the state of the art and the lessons learned.

  • 302.
    Akke, Mikael
    et al.
    Department of Biophysical Chemistry, Lund University.
    Lundström, Patrik
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär Bioteknik. Linköpings universitet, Tekniska högskolan.
    Conformational Dynamics by Relaxation Dispersion2012Ingår i: Encyclopedia of Biophysics / [ed] Gordon C. K. Roberts., Elsevier, 2012Kapitel i bok, del av antologi (Övrigt vetenskapligt)
    Abstract [en]

    The Encyclopedia of Biophysics is envisioned both as an easily accessible source of information and as an introductory guide to the scientific literature. It includes entries describing both Techniques and Systems. In the Techniques entries, each of the wide range of methods which fall under the heading of Biophysics are explained in detail, together with the value and the limitations of the information each provides. Techniques covered range from diffraction (X-ray, electron and neutron) through a wide range of spectroscopic methods (X-ray, optical, EPR, NMR) to imaging (from electron microscopy to live cell imaging and MRI), as well as computational and simulation approaches.In the Systems entries, biophysical approaches to specific biological systems or problems – from protein and nucleic acid structure to membranes, ion channels and receptors – are described. These sections, which place emphasis on the integration of the different techniques, therefore provide an inroad into Biophysics from a biological more than from a technique-oriented physical/chemical perspective. Thus the Encyclopedia is intended to provide a resource both for biophysicists interested in methods beyond those used in their immediate sub-discipline and for those readers who are approaching biophysics from either a physical or biological background.

  • 303.
    Akoto, Brenda
    Linköpings universitet, Institutionen för fysik, kemi och biologi. Linköpings universitet, Tekniska högskolan.
    Is spring burning a viable management tool for species-rich grasslands?2012Självständigt arbete på avancerad nivå (masterexamen), 80 poäng / 120 hpStudentuppsats (Examensarbete)
    Abstract [en]

    Semi- natural grasslands are species-rich and also one of the most threatened biotopes in Europe. The area of these grasslands has declined and grassland vegetation is threatened as a result of lack of management and land use change. Appropriate management is therefore required to maintain the conservation values and high species richness of semi- natural grasslands. Traditional management, that is, grazing or annual mowing is expensive, which motivates evaluation of alternative cheaper methods of management. Burning is less costly and therefore I evaluated burning along with the conventional methods. The study addressed the main question: is burning an option to mowing and grazing? I searched the literature for available studies suitable for metaanalysis, but located only detailed reports from a series of eleven Swedish long-term field trials. In addition, I collected data in the only one of these trials still running. To facilitate metaanalysis, l used different indicator systems of classification of grassland plants then calculating the odds for a random record being an indicator after one, eight, fourteen, twenty-eight and thirty-nine spring burns. The results show an increasing proportion of grassland indicators of good management in the mowed and grazed plots compared with the burnt plots, indicating a general negative effect of burning on grassland plants compared with mowing and grazing. Hence, burning is not an appropriate long-term management method if the aim is to maintain vegetation diversity in semi-natural grassland.

  • 304.
    Akram Hassan, Kahin
    et al.
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Medie- och Informationsteknik. Linköpings universitet, Tekniska fakulteten.
    Rönnberg, Niklas
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Medie- och Informationsteknik. Linköpings universitet, Tekniska fakulteten.
    Forsell, Camilla
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Medie- och Informationsteknik. Linköpings universitet, Tekniska fakulteten.
    Johansson, Jimmy
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Medie- och Informationsteknik. Linköpings universitet, Tekniska fakulteten. Linköpings universitet, Centrum för klimatpolitisk forskning, CSPR.
    On the Performance of Stereoscopic Versus Monoscopic 3D Parallel Coordinates2016Konferensbidrag (Refereegranskat)
    Abstract [en]

    This work presents the results from an evaluation of stereoscopic versus monoscopic 3D parallel coordinates. The objective of the evaluation was to investigate if stereopsis increases user performance. The results show that stereoscopy has no effect at all on user performance compared to monoscopy. This result is important when it comes to the potential use of stereopsis within the information visualization community.

  • 305.
    Akram, Usman
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi. Linköpings universitet, Tekniska fakulteten.
    Metson, Genevieve
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi. Linköpings universitet, Tekniska fakulteten. Linköpings universitet, Centrum för klimatpolitisk forskning, CSPR.
    Quttineh, Nils-Hassan
    Linköpings universitet, Matematiska institutionen, Optimeringslära. Linköpings universitet, Tekniska fakulteten.
    Wennergren, Uno
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi. Linköpings universitet, Tekniska fakulteten.
    Closing Pakistan’s yield gaps through nutrient recycling2018Ingår i: Frontiers in Sustainable Food Systems, E-ISSN 2571-581X, s. 1-14, artikel-id 00024Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Achieving food security will require closing yield gaps in many regions, including Pakistan. Although fertilizer subsidies have facilitated increased nitrogen (N) application rates, many staple crop yields have yet to reach their maximum potential. Considering that current animal manure and human excreta (bio-supply) recycling rates are low, there is substantial potential to increase the reuse of nutrients in bio-supply. We quantified 2010 crop N, phosphorus (P), and potassium (K) needs along with bio-supply nutrient availability for Pakistani districts, and compared these values to synthetic fertilizer use and costs. We found that synthetic fertilizer use combined with low bio-supply recycling resulted in a substantial gap between nutrient supply and P and K crop needs, which would cost 3 billion USD to fill with synthetic fertilizers. If all bio-supply was recycled, it could eliminate K synthetic fertilizer needs and decrease N synthetic fertilizer needs to 43% of what was purchased in 2010. Under a full recycling scenario, farmers would still require an additional 0.28 million tons of synthetic P fertilizers, costing 2.77 billion USD. However, it may not be prohibitively expensive to correct P deficiencies. Pakistan already spends this amount of money on fertilizers. If funds used for synthetic N were reallocated to synthetic P purchases in a full bio-supply recycling scenario, crop needs could be met. Most recycling could happen within districts, with only 6% of bio-supply requiring between-district transport when optimized to meet national N crop needs. Increased recycling in Pakistan could be a viable way to decrease yield gaps.

  • 306.
    Akram, Usman
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi. Linköpings universitet, Tekniska fakulteten.
    Quttineh, Nils-Hassan
    Linköpings universitet, Matematiska institutionen, Optimeringslära. Linköpings universitet, Tekniska fakulteten.
    Wennergren, Uno
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi. Linköpings universitet, Tekniska fakulteten.
    Tonderski, Karin
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi. Linköpings universitet, Tekniska fakulteten.
    Metson, Genevieve
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi. Linköpings universitet, Tekniska fakulteten.
    Enhancing nutrient recycling from excreta to meet crop nutrient needs in Sweden - a spatial analysis2019Ingår i: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 9, artikel-id 10264Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Increased recycling of nutrient-rich organic waste to meet crop nutrient needs is an essential component of a more sustainable food system. However, agricultural specialization continues to pose a significant challenge to balancing crop nutrient needs and the nutrient supply from animal manure and human excreta locally. For Sweden, this study found that recycling all excreta (in 2007) could meet up to 75% of crop nitrogen and 81% of phosphorus needs, but that this would exceed crop potassium needs by 51%. Recycling excreta within municipalities could meet 63% of crop P nutrient needs, but large regional differences and imbalances need to be corrected to avoid over or under fertilizing. Over 50% of the total nitrogen and phosphorus in excreta is contained in just 40% of municipalities, and those have a surplus of excreta nutrients compared to crop needs. Reallocation of surpluses (nationally optimized for phosphorus) towards deficit municipalities, would cost 192 million USD (for 24 079 km of truck travel). This is 3.7 times more than the total NPK fertilizer value being transported. These results indicate that Sweden could reduce its dependence on synthetic fertilizers through investments in excreta recycling, but this would likely require valuing also other recycling benefits.

  • 307.
    Akram, Usman
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi.
    Quttineh, Nils-Hassan
    Linköpings universitet, Matematiska institutionen, Optimeringslära.
    Wennergren, Uno
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi.
    Tonderski, Karin
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Biologi.
    Metson, Geneviéve S.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi.
    Optimizing Nutrient Recycling From Excreta in Sweden and Pakistan: Higher Spatial Resolution Makes Transportation More Attractive2019Ingår i: Frontiers in Sustainable Food Systems, ISSN 2571-581X, Vol. 3Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Recycling essential plant nutrients like nitrogen (N), phosphorus (P), and potassium (K) from organic waste such as human and animal excreta will be an essential part of sustainable food systems and a circular economy. However, transportation is often cited as a major barrier to increased recycling as organic waste is heavy and bulky, and distances between areas of abundant waste may be far from areas with a need for fertilizers. We investigated the effect of increased input data spatial resolution to an optimization model on the weight, distance, and spatial patterns of transport. The model was run in Sweden and in Pakistan to examine cost-effectiveness of transporting excess excreta to areas of crop need after local recycling. Increasing the resolution of input data from political boundaries (municipalities and districts) to 0.083 decimal grids increased the amount of N requiring transport by 12% in Pakistan and increased P requiring transport by 14% in Sweden. The average distance decreased by 67% (to 44 km) in Pakistan but increased by 1 km in Sweden. Further increasing the resolution to 5 km grids in Sweden decreased the average transportation distance by 9 km (down to 123 km). In both countries, increasing resolution also decreased the number of long-distance heavy transports, and as such costs did not increase as much as total distance and weight transported. Ultimately, transportation in Pakistan seemed financially beneficial: the cost of transport only represented 13% of the NPK fertilizer value transported, and total recycling could even cover 78% of additional fertilizer purchases required. In Sweden, the cost of transporting excreta did not seem cost effective without valuing other potential benefits of increased recycling: costs were three times higher than the fertilizer value transported in excreta at the 5 km resolution. In summary, increasing input data resolution created a more realistic picture of recycling needs. This also highlighted more favorable cost to fertilizer value ratios which could make it easier to move forward with industry and government partners to facilitate productive recycling. Our analysis shows that in both countries increased recycling can result in better spatial nutrient balances.

  • 308.
    Al Haji, Ghazwan
    et al.
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Fowler, Scott
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Andersson Granberg, Tobias
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Kommunikations- och transportsystem. Linköpings universitet, Tekniska fakulteten.
    Smart traffic calming measures for smart cities - a pre-study2018Rapport (Övrigt vetenskapligt)
    Abstract [sv]

    Trafiklugnande åtgärder, såsom vägbulor och förhöjda övergångsställen, används för att minska hastigheten, hindra farliga omkörningar och generellt bidra till en säkrare trafiksituation. Dock kan de också bidra till att insatstiderna för räddningsfordon (t.ex. ambulanser eller räddningstjänstens släckbilar) förlängs. Ett alternativ till de konventionella trafiklugnande åtgärderna, är s.k. smarta trafiklugnade åtgärder. Dessa kan avgöra när ett fordon närmar sig, vars färd inte bör hindras, och anpassa sig så att fri färd för detta fordon tillåts.

    I denna rapport ges en översikt av problemet, och några exempel på smarta trafiklugnade åtgärder diskuteras, med fokus på sådana som hämtar information och styrs med hjälp av trådlös kommunikation. Vidare diskuteras existerande utmaningar och möjliga lösningar för trafiklugnande åtgärder och den kommunikation som krävs för att göra dem smarta.

  • 309.
    Alagia, M.
    et al.
    ISMN-CNR, Sez. Roma1, P.le A. Moro 5, I-00185 Roma, Italy and TASC-CNR, Area Science Park, Basovizza, I-34012 Trieste, Italy.
    Lavollée, M.
    LIXAM-CNRS, F-91898 Orsay-Cedex, France.
    Richter, R.
    Sincrotrone Trieste, Area Science Park, I-34012 Basovizza, Trieste, Italy.
    Ekström, Ulf
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Beräkningsfysik. Linköpings universitet, Tekniska högskolan.
    Carravetta, V.
    Institute of Chemical Physical Processes (CNR), Via Moruzzi 1, I-56124 Pisa, Italy.
    Stranges, D.
    Dipartimento di Chimica and INSTM, Universitá La Sapienza, P.le A. Moro 5, I-00185 Roma, Italy and ISMN-CNR, Sez. Roma1, P.le A. Moro 5, I-00185 Roma, Italy.
    Brunetti, B.
    ISMN-CNR, Sez. Roma1, P.le A. Moro 5, I-00185 Roma, Italy.
    Stranges, S.
    Dipartimento di Chimica and INSTM, Universitá La Sapienza, P.le A. Moro 5, I-00185 Roma, Italy; ISMN-CNR, Sez. Roma1, P.le A. Moro 5, I-00185 Roma, Italy; and TASC-CNR, Area Science Park, Basovizza, I-34012 Trieste, Italy.
    Probing the potential energy surface by highresolution x-ray absorption spectroscopy: The umbrella motion of the coreexcited CH3 free radical2007Ingår i: Physical Review. A, ISSN 1050-2947, Vol. 76, nr 2, s. 124305-Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A detailed study of the umbrellalike vibration in inner-shell spectroscopy is presented. The high-resolution x-ray absorption spectrum for the lowest lying core excitation of the CH3 free radical was recorded. High quality potential energy surfaces (PES) for the initial and final states of the transition were calculated as a function of the symmetrical stretching and the umbrella deformation coordinates. The strong anharmonicity along the umbrella coordinate in the double-well region of the PES of the core excited state has a strong effect on the bending vibrational progressions. The excellent agreement between the experiment and theory allows an accurate spectroscopic characterization of the vibrational structure of the electronic transition, and the estimation of the umbrella inversion time of 149  fs.

  • 310.
    Alagia, Michele
    et al.
    ISMN-CNR, Rom.
    Baldacchini, Chiara
    Università di Roma "La Sapienza" .
    Betti, Maria Grazia
    Università di Roma "La Sapienza" .
    Bussolotti, Fabio
    Università di Modena e Reggio Emilia.
    Carravetta, Vincenzo
    IPCF-CNR, Pisa.
    Ekström, Ulf
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Beräkningsfysik. Linköpings universitet, Tekniska högskolan.
    Mariani, Carlo
    Università di Roma "La Sapienza" .
    Stranges, Stefano
    Università di Roma "La Sapienza" .
    Core-shell photoabsorption and photoelectron spectra of gas-phase pentacene: Experiment and theory2005Ingår i: Journal of chemical physics Online, ISSN 1089-7690, Vol. 122, nr 12, s. 124305-Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The C K-edge photoabsorption and 1s core-level photoemission of pentacene (C22H14) free molecules are experimentally measured, and calculated by self-consistent-field and static-exchange approximation ab initio methods. Six nonequivalent C atoms present in the molecule contribute to the C 1s photoemission spectrum. The complex near-edge structures of the carbon K-edge absorption spectrum present two main groups of discrete transitions between 283 and 288  eV photon energy, due to absorption to * virtual orbitals, and broader structures at higher energy, involving * virtual orbitals. The sharp absorption structures to the * empty orbitals lay well below the thresholds for the C 1s ionizations, caused by strong excitonic and localization effects. We can definitely explain the C K-edge absorption spectrum as due to both final (virtual) and initial (core) orbital effects, mainly involving excitations to the two lowest-unoccupied molecular orbitals of * symmetry, from the six chemically shifted C 1s core orbitals. ©2005 American Institute of Physics

  • 311.
    Alami, Jones
    Linköpings universitet, Institutionen för fysik och mätteknik. Linköpings universitet, Tekniska högskolan.
    Plasma characterisation in high power pulsed magnetron sputtering2003Licentiatavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [en]

    In this thesis, plasma parameters including plasma and floating potentials, electron energy distribution function (EEDF) plasma density and electron temperature are studied in a high power pulsed magnetron (HPPM) discharge at different Argon (Ar) gas pressures and different magnetron powers. It is reported that the EEDF during and shortly after the pulse can be represented by a bi-Maxwellian distribution indicating two energy groups of electrons.

    Furthermore, we report on the variation of the plasma parameters and electron energy distribution function with gas pressure in the pressure range 0.5-20 mtorr. At a high pressure (> 10 mTorr) two density peaks are present, the second of which occurs hundreds of microseconds after the pulse is switched off. It shows that the second peaks occurrence depends on the target material used as well as the chamber pressure and the magnetron power. It is found that the electron density is very high (up to 1019 m-3, during the whole of the measured 2000 µs, indicating the importance of the second density peak in maintaining the high plasma density.

    Measurements on the electron temperature show that this does not exceed 3 eV while the pulse is on, and that it is no more than 0.5 after the pulse is off. A movie is constructed using Langmuir probe measurements data, showing the temporal evolution of the plasma at 20 mTorr argon pressure and 11 J pulse energy. Analysis shows the existence of a magnetic trap underneath the center of the target. Furthermore, the electron flux in the substrate vicinity 10 - 12 cm from the target is found to be homogeneous. Ti thin films are grown along the sidewalls of a hole, 1 cm2 in area and 2 cm in depth, using both de magnetron and HPPM sputtering. Secondary electron microscopy shows that the film grown by de magnetron sputtering shows clear columnar growth, while a dense and flat film was produced using the HPPM sputtering technique.

  • 312.
    Alami, Jones
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    Eklund, Per
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Andersson, Jon M.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    Lattemann, Martina
    Linköpings universitet, Institutionen för fysik, kemi och biologi. Linköpings universitet, Tekniska högskolan.
    Wallin, Erik
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    Böhlmark, Johan
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    Persson, Per
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Helmersson, Ulf
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    Phase tailoring of Ta thin films by highly ionized pulsed magnetron sputtering2007Ingår i: Thin Solid Films, ISSN 0040-6090, E-ISSN 1879-2731, Vol. 515, nr 7-8, s. 3434-3438Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Ta thin films were grown on Si substrates at different inclination angles with respect to the sputter source using high power impulse magnetron sputtering (HIPIMS), an ionized physical vapor deposition technique. The ionization allowed for better control of the energy and directionality of the sputtered species, and consequently for improved properties of the deposited films. Depositions were made on Si substrates with the native oxide intact. The structure of the as deposited films was investigated using X-ray diffraction, while a four-point probe setup was used to measure the resistivity. A substrate bias process-window for growth of bcc-Ta was observed. However, the process-window position changed with changing inclination angles of the substrate. The formation of this low-resistivity bcc-phase could be understood in light of the high ion flux from the HIPIMS discharge.

  • 313.
    Alami, Jones
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    Eklund, Per
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Emmerlich, Jens
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Wilhelmsson, O.
    Department of Materials Chemistry, The Ångström Laboratory, Uppsala University, Uppsala, Sweden.
    Jansson, U.
    Department of Materials Chemistry, The Ångström Laboratory, Uppsala University, Uppsala, Sweden.
    Högberg, Hans
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Hultman, Lars
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Helmersson, Ulf
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    High-power impulse magnetron sputtering of Ti-Si-C thin films from a Ti3SiC2 compound target2006Ingår i: Thin Solid Films, ISSN 0040-6090, E-ISSN 1879-2731, Vol. 515, nr 4, s. 1731-1736Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    We have deposited Ti-Si-C thin films using high-power impulse magnetron sputtering (HIPIMS) from a Ti3SiC2 compound target. The as-deposited films were composite materials with TiC as the main crystalline constituent. X-ray diffraction and photoelectron spectroscopy indicated that they also contained amorphous SiC, and for films deposited on inclined substrates, crystalline Ti5Si3Cx. The film morphology was dense and flat, while films deposited with dc magnetron sputtering under comparable conditions were rough and porous. Due to the high degree of ionization of the sputtered species obtained in HIPIMS, it is possible to control the film composition, in particular the C content, by tuning the substrate inclination angle, the Ar process pressure, and the bias voltage.

  • 314.
    Alami, Jones
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    Persson, Per O. Å.
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Music, Denis
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Gudmundsson, J. T.
    University of Iceland, Reykjavik.
    Böhlmark, Johan
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    Helmersson, Ulf
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Plasma och beläggningsfysik. Linköpings universitet, Tekniska högskolan.
    Ion-assisted Physical Vapor Deposition for enhanced film properties on non-flat surfaces2005Ingår i: Journal of Vacuum Science & Technology. A. Vacuum, Surfaces, and Films, ISSN 0734-2101, E-ISSN 1520-8559, Vol. 23, nr 2, s. 278-280Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    We have synthesized Ta thin films on Si substrates placed along a wall of a 2-cm-deep and 1-cm-wide trench, using both a mostly neutral Ta flux by conventional dc magnetron sputtering (dcMS) and a mostly ionized Ta flux by high-power pulsed magnetron sputtering (HPPMS). Structure of the grown films was evaluated by scanning electron microscopy, transmission electron microscopy, and atomic force microscopy. The Ta thin film grown by HPPMS has a smooth surface and a dense crystalline structure with grains oriented perpendicular to the substrate surface, whereas the film grown by dcMS exhibits a rough surface, pores between the grains, and an inclined columnar structure. The improved homogeneity achieved by HPPMS is a direct consequence of the high ion fraction of sputtered species.

  • 315.
    Alansari, Hayder
    Linköpings universitet, Institutionen för datavetenskap.
    Clustered Data Management in Virtual Docker Networks Spanning Geo-Redundant Data Centers: A Performance Evaluation Study of Docker Networking2017Självständigt arbete på avancerad nivå (masterexamen), 20 poäng / 30 hpStudentuppsats (Examensarbete)
    Abstract [en]

    Software containers in general and Docker in particular is becoming more popular both in software development and deployment. Software containers are intended to be a lightweight virtualization that provides the isolation of virtual machines with a performance that is close to native. Docker does not only provide virtual isolation but also virtual networking to connect the isolated containers in the desired way. Many alternatives exist when it comes to the virtual networking provided by Docker such as Host, Macvlan, Bridge, and Overlay networks. Each of these networking solutions has its own advantages and disadvantages.

    One application that can be developed and deployed in software containers is data grid system. The purpose of this thesis is to measure the impact of various Docker networks on the performance of Oracle Coherence data grid system. Therefore, the performance metrics are measured and compared between native deployment and Docker built-in networking solutions. A scaled-down model of a data grid system is used along with benchmarking tools to measure the performance metrics.

    The obtained results show that changing the Docker networking has an impact on performance. In fact, some results suggested that some Docker networks can outperform native deployment. The conclusion of the thesis suggests that if performance is the only consideration, then Docker networks that showed high performance can be used. However, real applications require more aspects than performance such as security, availability, and simplicity. Therefore Docker network should be carefully selected based on the requirements of the application.

  • 316.
    Alarcon, Emilio I.
    et al.
    University of Ottawa, Canada; University of Ottawa, Canada; University of Ottawa, Canada.
    Udekwu, Klas I.
    Karolinska Institute, Sweden.
    Noel, Christopher W.
    University of Ottawa, Canada; .
    Gagnon, Luke B. -P.
    University of Ottawa, Canada.
    Taylor, Patrick K.
    University of Ottawa, Canada.
    Vulesevic, Branka
    University of Ottawa, Canada.
    Simpson, Madeline J.
    University of Ottawa, Canada.
    Gkotzis, Spyridon
    Karolinska Institute, Sweden.
    Islam, Mohammed Mirazul
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för cellbiologi. Linköpings universitet, Medicinska fakulteten. Karolinska Institute, Sweden.
    Lee, Chyan-Jang
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Sensorvetenskap och Molekylfysik. Linköpings universitet, Tekniska högskolan.
    Richter-Dahlfors, Agneta
    Karolinska Institute, Sweden.
    Mah, Thien-Fah
    University of Ottawa, Canada.
    Suuronen, Erik J.
    University of Ottawa, Canada.
    Scaiano, Juan
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för cellbiologi. Linköpings universitet, Medicinska fakulteten. University of Ottawa, Canada.
    Griffith, May
    Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för cellbiologi. Linköpings universitet, Medicinska fakulteten. Karolinska Institute, Sweden.
    Safety and efficacy of composite collagen-silver nanoparticle hydrogels as tissue engineering scaffolds2015Ingår i: Nanoscale, ISSN 2040-3364, E-ISSN 2040-3372, Vol. 7, nr 44, s. 18789-18798Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The increasing number of multidrug resistant bacteria has revitalized interest in seeking alternative sources for controlling bacterial infection. Silver nanoparticles (AgNPs), are amongst the most promising candidates due to their wide microbial spectrum of action. In this work, we report on the safety and efficacy of the incorporation of collagen coated AgNPs into collagen hydrogels for tissue engineering. The resulting hybrid materials at [AgNPs] less than0.4 mu M retained the mechanical properties and biocompatibility for primary human skin fibroblasts and keratinocytes of collagen hydrogels; they also displayed remarkable anti-infective properties against S. aureus, S. epidermidis, E. coli and P. aeruginosa at considerably lower concentrations than silver nitrate. Further, subcutaneous implants of materials containing 0.2 mu M AgNPs in mice showed a reduction in the levels of IL-6 and other inflammation markers (CCL24, sTNFR-2, and TIMP1). Finally, an analysis of silver contents in implanted mice showed that silver accumulation primarily occurred within the tissue surrounding the implant.

  • 317.
    Alazawi, Salah
    et al.
    ISY, DATORSYSTEM, DI.
    Alilovic, Bojan
    ISY, DATORSSYTEM, DI.
    Konstruktion av Ethernet-baserad Qbussförlängare2008Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats
    Abstract [sv]

     

    Syftet med var att konstruera ett bussförlängartkort till Qbussen som gör Ethernet-baserad kommunikation med I/O:t möjlig. Kortet ska kunna anslutas till standard 100 Mbits nätverksutrustning och klara autoförhandling och låsning av hastighet och duplex. Detta minskar på många ställen kabeldragningen väsentligt och det är därför önskvärt att SSAB:s egna I/O ska kunna köras så över Ethernet, antingen över vanliga nätverket eller på dedikerad kabel.

  • 318.
    Albert, Frank W.
    et al.
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, and Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America,.
    Somel, Mehmet
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, CAS–MPG Partner Institute for Computational Biology SIBS, Shanghai, China.
    Carneiro, Miguel
    CIBIO, Centro de Investigac¸a˜o em Biodiversidade e Recursos Gene´ ticos, Vaira˜o, Portugal, and Departamento de Zoologia e Antropologia–Faculdade de Cieˆncias da Universidade do Porto, Porto, Po.
    Aximu-Petri, Ayinuer
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
    Halbwax, Michael
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany and Fernan Vaz Gorilla Project, Port-Gentil, Gabon.
    Thalmann, Olaf
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany and Department of Biology, University of Turku, Turku, Finland.
    Blanco-Aguiar, Jose A.
    CIBIO, Centro de Investigac¸a˜o em Biodiversidade e Recursos Gene´ ticos, Vaira˜o, Portugal, 5 Departamento de Zoologia e Antropologia–Faculdade de Cieˆncias da Universidade do Porto, Porto, Portugal and Instituto de Investigacio´n en Recursos Cinege´ticos, IREC (CSIC, UCLM, JCCM), Ciudad Real, Spain.
    Plyusnina, Irina Z.
    Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
    Trut, Lyudmila
    Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.
    Villafuerte, Rafael
    Instituto de Investigacio´n en Recursos Cinege´ticos, IREC (CSIC, UCLM, JCCM), Ciudad Real, Spain.
    Ferrand, Nuno
    CIBIO, Centro de Investigac¸a˜o em Biodiversidade e Recursos Gene´ ticos, Vaira˜o, Portugal, and Departamento de Zoologia e Antropologia–Faculdade de Cieˆncias da Universidade do Porto, Porto, Portugal.
    Kaiser, Sylvia
    Department of Behavioural Biology, University of Mu¨ nster, Mu¨ nster, Germany.
    Jensen, Per
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Zoologi. Linköpings universitet, Tekniska högskolan.
    Pääbo, Svante
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
    A Comparison of Brain Gene Expression Levels in Domesticated and Wild Animals2012Ingår i: PLOS Genetics, ISSN 1553-7390, Vol. 8, nr 9, s. e1002962-Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Domestication has led to similar changes in morphology and behavior in several animal species, raising the questionwhether similarities between different domestication events also exist at the molecular level. We used mRNA sequencing toanalyze genome-wide gene expression patterns in brain frontal cortex in three pairs of domesticated and wild species (dogsand wolves, pigs and wild boars, and domesticated and wild rabbits). We compared the expression differences with thosebetween domesticated guinea pigs and a distant wild relative (Cavia aperea) as well as between two lines of rats selectedfor tameness or aggression towards humans. There were few gene expression differences between domesticated and wilddogs, pigs, and rabbits (30–75 genes (less than 1%) of expressed genes were differentially expressed), while guinea pigs andC. aperea differed more strongly. Almost no overlap was found between the genes with differential expression in thedifferent domestication events. In addition, joint analyses of all domesticated and wild samples provided only suggestiveevidence for the existence of a small group of genes that changed their expression in a similar fashion in differentdomesticated species. The most extreme of these shared expression changes include up-regulation in domesticates of SOX6and PROM1, two modulators of brain development. There was almost no overlap between gene expression in domesticatedanimals and the tame and aggressive rats. However, two of the genes with the strongest expression differences betweenthe rats (DLL3 and DHDH) were located in a genomic region associated with tameness and aggression, suggesting a role ininfluencing tameness. In summary, the majority of brain gene expression changes in domesticated animals are specific tothe given domestication event, suggesting that the causative variants of behavioral domestication traits may likewise bedifferent.

  • 319.
    Alberti, Esteban
    et al.
    Department of Neurobiology, International Center of Neurological Restoration, CIREN, Havana, Cuba..
    Los, Marek Jan
    Interfaculty Institute for Biochemistry, University of Tübingen, Germany; BioApplications Enterprises, Winnipeg, MB, Canada.
    Garcia, Rocio
    Department of Neurobiology, International Center of Neurological Restoration, CIREN, Havana, Cuba..
    Fraga, JL
    Department of Neurobiology, International Center of Neurological Restoration, CIREN, Havana, Cuba..
    Serrano, T.
    Department of Neurobiology, International Center of Neurological Restoration, CIREN, Havana, Cuba..
    Hernandez, E.
    Department of Neurobiology, International Center of Neurological Restoration, CIREN, Havana, Cuba..
    Klonisch, Thomas
    Department of Human Anatomy and Cell Sciences, and Manitoba Institute of Child Health, Winnipeg, Canada.
    Macías, R.
    Department of Neurobiology, International Center of Neurological Restoration, CIREN, Havana, Cuba..
    Martinez, L.
    Department of Neurobiology, International Center of Neurological Restoration, CIREN, Havana, Cuba..
    Castillo, L.
    Department of Neurobiology, International Center of Neurological Restoration, CIREN, Havana, Cuba..
    de la Cuétara, K.
    Department of Neurobiology, International Center of Neurological Restoration, CIREN, Havana, Cuba.
    Prolonged Survival and expression of neural markers by bone marrow-derived stem cells transplanted into brain lesions2009Ingår i: Medical Science Monitor, ISSN 1234-1010, E-ISSN 1643-3750, Vol. 15, nr 2, s. BR47-BR54Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Bone marrow-derived stem cell transplantation is a potentially viable therapeutic option for the treatment of neurodegenerative disease. MATERIAL/METHODS: We have isolated bone marrow stem cells by standard method. We then evaluated the survival of rats' bone marrow mononuclear cells implanted in rats' brain. The cells were extracted from rats' femurs, and marked for monitoring purposes by adenoviral transduction with Green Fluorescent Protein (GFP). Labeled cells were implanted within the area of rats' striatum lesions that were induced a month earlier employing quinolinic acid-based method. The implants were phenotyped by monitoring CD34; CD38; CD45 and CD90 expression. Bone marrow stromal cells were extracted from rats' femurs and cultivated until monolayer bone marrow stromal cells were obtained. The ability of bone marrow stromal cells to express NGF and GDNF was evaluated by RT-PCR. RESULTS: Implanted cells survived for at least one month after transplantation and dispersed from the area of injection towards corpus callosum and brain cortex. Interestingly, passaged rat bone marrow stromal cells expressed NGF and GDNF mRNA. CONCLUSIONS: The bone marrow cells could be successfully transplanted to the brain either for the purpose of trans-differentiation, or for the expression of desired growth factors.

  • 320.
    Alberti, Marco
    et al.
    Dept. of Computer Science, Nova Universidade de Lisboa, Lisbon.
    Dell'Acqua, Pierangelo
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Medie- och Informationsteknik. Linköpings universitet, Tekniska högskolan.
    Pereira, Luis M
    Dept. of Computer Science, Nova Universidade de Lisboa, Lisbon.
    Observation Strategies for Event Detection with Incidence on Runtime Verification: Theory, Algorithms, Experimentation2011Ingår i: Annals of Mathematics and Artificial Intelligence, ISSN 1012-2443, E-ISSN 1573-7470, Vol. 62, nr 3-4, s. 161-186Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Many applications (such as system and user monitoring, runtime verification, diagnosis, observation-based decision making, intention recognition) all require to detect the occurrence of an event in a system, which entails the ability to observe the system. Observation can be costly, so it makes sense to try and reduce the number of observations, without losing full certainty about the event’s actual occurrence. In this paper, we propose a formalization of this problem. We formally show that, whenever the event to be detected follows a discrete spatial or temporal pattern, then it is possible to reduce the number of observations. We discuss exact and approximate algorithms to solve the problem, and provide an experimental evaluation of them. We apply the resulting algorithms to verification of linear temporal logics formulæ. Finally, we discuss possible generalizations and extensions, and, in particular, how event detection can benefit from logic programming techniques.

  • 321.
    Albertsson, Marcus
    et al.
    Linköpings universitet, Institutionen för datavetenskap.
    Öberg Bustad, Adrian
    Linköpings universitet, Institutionen för datavetenskap.
    Sundmark, Mattias
    Linköpings universitet, Institutionen för datavetenskap.
    Gerde, Elof
    Linköpings universitet, Institutionen för datavetenskap.
    Boberg, Jessika
    Linköpings universitet, Institutionen för datavetenskap.
    Abdulla, Ariyan
    Linköpings universitet, Institutionen för datavetenskap.
    Danielsson, Oscar
    Linköpings universitet, Institutionen för datavetenskap.
    Johnsson Bittmann, Felicia
    Linköpings universitet, Institutionen för datavetenskap.
    Moberg, Anton
    Linköpings universitet, Institutionen för datavetenskap.
    Hur en webbapplikation kan utvecklas för att leverera säkerhet, handlingsbarhet och navigerbarhet: PimpaOvven – Utveckling av en e-butik för märken och accessoarer till studentoveraller2017Självständigt arbete på grundnivå (kandidatexamen), 12 poäng / 18 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Bland studenter på många av Sveriges Universitet är studentoverallen en vedertagen ägodel. Studenter gillar att utsmycka sina overaller med olika tygmärken och andra accessoarer, men tillgängligheten av dessa är i dagsläget begränsad.  Denna rapport presenterar utvecklingsprocessen samt resultatet av webbapplikationen ”PimpaOvven” – en e-shop med syfte att öka tillgängligheten av tygmärken och overallstillbehör. Utvecklingen har skett iterativt och fokuserats till att bygga en säker webbapplikation som genererar en användbar miljö i avseende till handlingsbarhet, navigerbarhet, säkerhet och inger ett säkert intryck. De metoder som använts och genererat den resulterande webbapplikationen utgör tillsammans med den teoretiska referensramen grunden för rapportens diskussion. Under projektets gång genomfördes även användbarhets- samt säkerhetstester, och utifrån dessa tillsammans med diskussionen drogs slutsatsen att en säker och användbar webbapplikation utvecklats.

  • 322.
    Albertsson, Sarah
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Tekniska fakulteten. SICS East Swedish ICT AB, Linköping, Sweden.
    Rennes, Evelina
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Tekniska fakulteten. SICS East Swedish ICT AB, Linköping, Sweden.
    Jönsson, Arne
    Linköpings universitet, Institutionen för datavetenskap, Interaktiva och kognitiva system. Linköpings universitet, Filosofiska fakulteten. SICS East Swedish ICT AB, Linköping, Sweden.
    Similarity-Based Alignment of Monolingual Corpora for Text Simplification2016Ingår i: CL4LC 2016 - Computational Linguistics for Linguistic Complexity: Proceedings of the Workshop, The COLING 2016 Organizing Committee , 2016, s. 154-163Konferensbidrag (Refereegranskat)
    Abstract [en]

    Comparable or parallel corpora are beneficial for many NLP tasks.  The automatic collection of corpora enables large-scale resources, even for less-resourced languages, which in turn can be useful for deducing rules and patterns for text rewriting algorithms, a subtask of automatic text simplification. We present two methods for the alignment of Swedish easy-to-read text segments to text segments from a reference corpus.  The first method (M1) was originally developed for the task of text reuse detection, measuring sentence similarity by a modified version of a TF-IDF vector space model. A second method (M2), also accounting for part-of-speech tags, was devel- oped, and the methods were compared.  For evaluation, a crowdsourcing platform was built for human judgement data collection, and preliminary results showed that cosine similarity relates better to human ranks than the Dice coefficient. We also saw a tendency that including syntactic context to the TF-IDF vector space model is beneficial for this kind of paraphrase alignment task.

  • 323.
    Albin, Gräns
    Linköpings universitet, Institutionen för fysik, kemi och biologi.
    Feto-Maternal: Communication in Broiler Chickens (Gallus gallus domesticus)2006Självständigt arbete på avancerad nivå (masterexamen), 20 poäng / 30 hpStudentuppsats (Examensarbete)
    Abstract [en]

    Bird incubation is a natural phenomenon that balances the needs of the parents for nourishment with the needs of the fetus for heat provision and protection. In this context, any means of communication between the fetus and the parents would have an adaptive value. The aim of the study was to investigate whether putative means of fetomaternal communication would correlate to physiological changes caused by environmental alterations. Oxygen consumption was used to measure fetal well being and six independent variables associated with fetal vocalizations and fetal movements were used to evaluate their potential for communicating the fetus statu quo. Broiler fetuses (Gallus gallus domesticus) of three developmental stages (day 18, internally pipped and externally pipped) were challenged by a stepwise reduction in ambient temperature down to 30ºC. A linear drop in oxygen consumption in response to lowered temperatures was found in all three developmental stages indicating that the fetus was affected by the temperature changes. No differences correlating with temperature variations were found in any of the variables associated with fetal vocalization. Fetal vocalizations are consequently not used to communicate the thermal status of the fetus. Movement occurrence, movement intensity and ventilation frequency, however, followed a “maximum peak” trend, with a highest response at the third temperature interval (35.0-35.5ºC). Considering that the lower limit of optimal development is between 35-36ºC, the results suggest that fetal movements can be of potential use to the incubating parent to assess the well-being of the fetus.

  • 324.
    Albin, Odervall
    et al.
    Linköpings universitet, Institutionen för datavetenskap.
    Philip, Montalvo
    Linköpings universitet, Institutionen för datavetenskap.
    Design and Evaluation of a Reliable Group Communication Protocol2016Självständigt arbete på grundnivå (kandidatexamen), 10,5 poäng / 16 hpStudentuppsats (Examensarbete)
    Abstract [en]

    In distributed systems it is often useful to ensure that messages sent between processes in a group are received by all group members. This thesis presents Reliable Non-Ordered Multicast Protocol (RNOMP). We argue that it achieves reliable multicast between processes in groups that processes can leave and join arbitrarily. The protocol has been implemented on top of a group membership simulation which allows evaluation of the performance of the protocol while varying packet loss and the frequency at which processes leaves and joins groups. After analyzing how the protocol handles certain situations we conclude that our protocol achieves reliability and performs well within certain parameter values.

  • 325. Albinsson, L.
    et al.
    Ansell, Ricky
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär genetik. Linköpings universitet, Tekniska högskolan.
    Drotz, Weine
    Swedish National Laboratory of Forensic Sciences, Linköping.
    Single DNA analysis approach of crime scene samples2009Ingår i: Book of Abstracts, 2009, s. 142-Konferensbidrag (Refereegranskat)
  • 326.
    Albinsson, L.
    et al.
    Swedish National Laboratory of Forensic Science, Linköping.
    Hedman, J.
    Swedish National Laboratory of Forensic Science, Linköping.
    Ansell, Ricky
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär genetik. Linköpings universitet, Tekniska högskolan.
    Verification of alleles by using peak height thresholds and quality control of STR profiling kits2011Ingår i: Forensic Science International: Genetics, Supplement Series, ISSN 1875-1768, Vol. 3, nr 1, s. e251-e252Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    In the autumn of 2010 SKL performed in-house validation of PowerPlex ESX 16 System (Promega). As the validation showed that very low amounts of DNA (∼10 pg) may provide correct allele callings (peaks above 50 rfu), we investigated the linear range, i.e., the interval of DNA amounts where a profile is well balanced and does not contain drop-outs and/or drop-ins. The linear range as indicated by our results is approximately from 0.5 ng (manufacturer's recommendation) to 2.0 ng of DNA. As minute DNA amounts may be detected using the kit, extra care needs to be taken not to report a contaminant allele as a part of the correct profile. A way to verify the correctness of a single donor profile in routine analysis, without using duplicate analysis, is to use conservative peak height thresholds. We determine STR marker specific peak height thresholds for each new lot of DNA profiling kits, based on the results from three different tests: heterozygote balance, signal intensity and repeatability, and PCR inhibitor tolerance. The tests also serve to verify the quality of the kit lot. Generally, the peak height thresholds vary between 200 and 250 rfu for heterozygote alleles, with doubled values used for homozygotes.

  • 327.
    Albinsson, L.
    et al.
    Swedish National Laboratory of Forensic Science (SKL), Linköping, Sweden.
    Hedman, J.
    Swedish National Laboratory of Forensic Science (SKL), Linköping, Sweden.
    Ansell, Ricky
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär genetik. Linköpings universitet, Tekniska högskolan.
    Verification of alleles by using peak height thresholds and quality control of STR profiling kits2011Ingår i: Book of Abstracts, 2011, s. 134-Konferensbidrag (Refereegranskat)
    Abstract [en]

    In the autumn of 2010 SKL performed in-house validation of PowerPlex ESX 16 System (Promega). As the validationshowed that very low amounts of DNA (< 10 pg) may provide correct allele callings (peaks above 50 rfu),we investigated the linear range, i.e., the interval of DNA amounts where a profile is well balanced and doesnot contain drop-outs and/or drop-ins. The linear range as indicated by our results is approximately from 0.5ng (manufacturer’s recommendation) to 2.0 ng of DNA. Profiles generated by less than 0.5 ng contained intralocus imbalances and/or drop-outs. Above 2.0 ng “bleed through” occurs due to overload of template-DNA.A way to verify the correctness of a profile, without knowing anything about the condition of the template-DNA, is to use peak height thresholds adjusted to each marker and batch of kits used. SKL performs a qualitycontrol and adjust thresholds for each batch of kits. Three main tests are performed; detection limit, inhibitortolerance and signal repeatability. The detection limit is examined to identify at which concentration intralocus imbalances and drop-outs start to increase. The ability to overcome inhibition is checked by analysingvarying amounts of blood extracted with Chelex. Finally a set of replicates of control DNA is amplified (0.5 ngtemplate-DNA) to calculate the mean peak height and standard deviation at each locus. Generally, the peakheight thresholds vary between 200 and 250 rfu for heterozygote peaks. To verify allelic peaks below the setpeak height thresholds, SKL uses consensus analysis.

  • 328.
    Albinsson, L.
    et al.
    Östergötlands Läns Landsting, Närsjukvården i östra Östergötland, Palliativt kompetenscentrum.
    Strang, P.
    Karolinska Institutet, FoUU, Stockholms Sjukhem, Stockholm, Sweden.
    Staff opinions about the leadership and organisation of municipal dementia care2002Ingår i: Health & Social Care in the Community, ISSN 0966-0410, E-ISSN 1365-2524, Vol. 10, nr 5, s. 313-322Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    The present study describes the opinions of experienced staff providing direct care to patients with dementia in municipal units in Sweden. The focus is mainly on leadership and other organisational factors. A purposeful sample of 31 staff members employed in municipal dementia care in both urban and rural areas in mid-Sweden were selected. Data were collected within a qualitative paradigm using semi-structured interviews which were tape-recorded and analysed using a modified phenomenographical approach. The nearly unanimous opinions of the interviewees indicated that there was a great lack of daily leadership in the units. Thus, few units had clearly formulated goals and few had regular care planning for their residents. Poorly developed teamwork was reported in the care of people with dementia especially regarding doctors, whose visits to the unit were too infrequent and too short, and did not include a direct exchange of information with other staff. In addition, little or no staff education and guidance/supervision was provided on a regular basis. In conclusion, without any unreasonable increase in cost, measures such as introducing clear leadership at the care unit level, concentrating on multi-professional teamwork, and providing education and guidance/supervision to the staff would probably result in better care for patients with dementia and their families.

  • 329.
    Albinsson, Linda
    et al.
    Biologienheten SKL.
    Hedman, Johannes
    Biologienheten SKL.
    Ansell, Ricky
    Biologienheten SKL.
    SKL byter DNA-kit2011Ingår i: Kriminalteknik, nr 1, s. 4-5Artikel i tidskrift (Övrig (populärvetenskap, debatt, mm))
  • 330.
    Albinsson, Linda
    et al.
    Swedish National Laboratory of Forensic Science (SKL), Linköping, Sweden.
    Norén, Lina
    Swedish National Laboratory of Forensic Science (SKL), Linköping, Sweden.
    Hedell, Ronny
    Swedish National Laboratory of Forensic Science (SKL), Linköping, Sweden.
    Ansell, Ricky
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Molekylär genetik. Linköpings universitet, Tekniska högskolan.
    Swedish population data and concordance for the kits PowerPlexÒ ESX 16 System, PowerPlexÒ ESI 16 System, AmpFlSTRÒ NGMTM, AmpFlSTRÒ SGM PlusTM and Investigator ESSplex2011Ingår i: Forensic Science International: Genetics, ISSN 1872-4973, E-ISSN 1878-0326, Vol. 5, nr 3, s. e89-e92Artikel i tidskrift (Övrigt vetenskapligt)
    Abstract [en]

    The European Standard Set of loci (ESS) has been extended with five additional short tandem repeat (STR) loci following the recommendations of the European Network of Forensic Science Institutes (ENFSI) and the European DNA Profiling Group (EDNAP) to increase the number of loci routinely used by the European forensic community. Subsequently, a new extended Swedish population database, based on 425 individuals, has been assembled using the new STR multiplex kits commercially available.

    Allele frequencies and statistical parameters of forensic interest for 15 autosomal STR loci (D3S1358, TH01, D21S11, D18S51, D10S1248, D1S1656, D2S1338, D16S539, D22S1045, vWA, D8S1179, FGA, D2S441, D12S391 and D19S433) were obtained from the analysis of the PowerPlex® ESX 16 System kit (Promega Corporation, USA). According to the data no evidence of deviations from Hardy–Weinberg equilibrium was found. The observed heterozygosity varies between 0.755 (TH01) and 0.892 (D1S1656). The power of discrimination was smallest for D22S1045 (0.869) and largest for D1S1656 (0.982) while the power of exclusion was smallest for TH01 (0.518) and largest for D1S1656 (0.778).

    A concordance study was performed on the five amplification systems: PowerPlex® ESX 16 System, PowerPlex® ESI 16 System (Promega Corporation, USA), AmpFlSTR® NGM™, AmpFlSTR® SGM Plus™ (Applied Biosystems, USA) and Investigator ESSplex (Qiagen, Germany) to reveal null alleles and other divergences between the kits. For the 425 DNA profiles included, AmpFlSTR® NGM™ revealed two null alleles, AmpFlSTR® SGM Plus™ revealed one, and Investigator ESSplex revealed a micro-variant, while the rest of the alleles showed full concordance between the kits tested.

  • 331.
    Albinsson, Per-Anders
    et al.
    Swedish Defence Research Agency.
    Dahlbäck, Nils
    Linköpings universitet, Institutionen för datavetenskap, NLPLAB - Laboratoriet för databehandling av naturligt språk. Linköpings universitet, Tekniska högskolan.
    Morin, Magnus
    Linköpings universitet, Institutionen för datavetenskap, ASLAB - Application Systems Laboratory. Linköpings universitet, Tekniska högskolan.
    Coupling Models of Complexity and Models of Cognition in a Systems Design Process2003Ingår i: Proceedings of the Conference People in Control 2003 (PIC2003), November 4-6, 2003, Amsterdam, The Netherlands. 2003, 2003Konferensbidrag (Refereegranskat)
  • 332.
    Albinsson, Pär-Anders
    et al.
    FOI.
    Dahlbäck, Nils
    Linköpings universitet, Tekniska högskolan. Linköpings universitet, Institutionen för datavetenskap, NLPLAB - Laboratoriet för databehandling av naturligt språk.
    Morin, Magnus
    Visuell Systemteknik.
    Coupling Models of Complexity and Models of Cognition in a Systems Design Process2004Konferensbidrag (Refereegranskat)
  • 333.
    Albonico, Andrea
    et al.
    Human Vision and Eye Movement Laboratory, Departments of Medicine (Neurology), Ophthalmology and Visual Sciences, Psychology, University of British Columbia, Vancouver, Canada.
    Furubacke, Amanda
    Linköpings universitet, Medicinska fakulteten. Human Vision and Eye Movement Laboratory, Departments of Medicine (Neurology), Ophthalmology and Visual Sciences, Psychology, University of British Columbia, Vancouver, Canada.
    Barton, Jason J. S.
    Human Vision and Eye Movement Laboratory, Departments of Medicine (Neurology), Ophthalmology and Visual Sciences, Psychology, University of British Columbia, Vancouver, Canada.
    Oruc, Ipek
    Department of Ophthalmology and Visual Sciences, University of British Columbia, Canada; Program in Neuroscience, University of British Columbia, Canada.
    Perceptual efficiency and the inversion effect for faces, words and houses2018Ingår i: Vision Research, ISSN 0042-6989, E-ISSN 1878-5646, Vol. 153, s. 91-97Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Face and visual word recognition are two key forms of expert visual processing. In the domain of object recognition, it has been suggested that expert processing is characterized by the use of different mechanisms from the ones involved in general object recognition. It has been suggested that one traditional marker of expert processing is the inversion effect. To investigate whether face and word recognition differ from general object recognition, we compared the effect of inversion on the perceptual efficiency of face and visual word recognition as well as on the recognition of a third, non-expert object category, houses. From the comparison of identification contrast thresholds to an ideal observer, we derived the efficiency and equivalent input noise of stimulus processing in both upright and inverted orientations. While efficiency reflects the efficacy in sampling the available information, equivalent input noise is associated with the degradation of the stimulus signal within the visual system. We hypothesized that large inversion effects for efficiency and/or equivalent input noise should characterize expert high-level processes, and asked whether this would be true for both faces and words, but not houses. However, we found that while face recognition efficiency was profoundly reduced by inversion, the efficiency of word and house recognition was minimally influenced by the orientation manipulation. Inversion did not affect equivalent input noise. These results suggest that even though faces and words are both considered expert processes, only the efficiency of the mechanism involved in face recognition is sensitive to orientation.

  • 334.
    Albouy, Camille
    et al.
    IFREMER, France.
    Archambault, Philippe
    Univ Laval, Canada.
    Appeltans, Ward
    UNESCO, Belgium.
    Araujo, Miguel B.
    CSIC, Spain; Univ Evora, Portugal; Univ Copenhagen, Denmark.
    Beauchesne, David
    Univ Quebec Rimouski, Canada.
    Cazelles, Kevin
    Univ Guelph, Canada.
    Cirtwill, Alyssa
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Teoretisk Biologi. Linköpings universitet, Tekniska fakulteten. Univ Canterbury, New Zealand.
    Fortin, Marie-Josee
    Univ Toronto, Canada.
    Galiana, Nuria
    CNRS, France.
    Leroux, Shawn J.
    Mem Univ, Canada.
    Pellissier, Loik
    Swiss Fed Inst Technol, Switzerland; Swiss Fed Res Inst WSL, Switzerland.
    Poisot, Timothee
    Univ Montreal, Canada; McGill Univ, Canada.
    Stouffer, Daniel B.
    Univ Canterbury, New Zealand.
    Wood, Spencer A.
    Univ Washington, WA 98195 USA.
    Gravel, Dominique
    Univ Montreal, Canada; Univ Sherbrooke, Canada.
    The marine fish food web is globally connected2019Ingår i: Nature Ecology & Evolution, E-ISSN 2397-334X, Vol. 3, nr 8, s. 1153-+Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The productivity of marine ecosystems and the services they provide to humans are largely dependent on complex interactions between prey and predators. These are embedded in a diverse network of trophic interactions, resulting in a cascade of events following perturbations such as species extinction. The sheer scale of oceans, however, precludes the characterization of marine feeding networks through de novo sampling. This effort ought instead to rely on a combination of extensive data and inference. Here we investigate how the distribution of trophic interactions at the global scale shapes the marine fish food web structure. We hypothesize that the heterogeneous distribution of species ranges in biogeographic regions should concentrate interactions in the warmest areas and within species groups. We find that the inferred global metaweb of marine fish-that is, all possible potential feeding links between co-occurring species-is highly connected geographically with a low degree of spatial modularity. Metrics of network structure correlate with sea surface temperature and tend to peak towards the tropics. In contrast to open-water communities, coastal food webs have greater interaction redundancy, which may confer robustness to species extinction. Our results suggest that marine ecosystems are connected yet display some resistance to perturbations because of high robustness at most locations.

  • 335.
    Albrektson, Maja
    Linköpings universitet, Institutionen för datavetenskap.
    Att skapa en användarcentrerad återkopplingsrapport: En designprocess kring data2019Självständigt arbete på grundnivå (kandidatexamen), 12 poäng / 18 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Människor utsätts för mer information än någonsin tidigare. För att underlätta processandet av information är det viktigt att presentera informationen på rätt sätt - anpassat efter användaren. Detta projekt genomfördes i samarbete med Linköpings kommun och det övergripande syftet var att undersöka hur man kan utforma ett gränssnitt för de återkopplingsrapporter som ska nå ut till anställda på företaget. För den första frågeställningen “Vad önskar förvaltningarna för information/data i en återkopplingsrapport?” valdes en kvalitativ ansats och en tematisk analys utfördes utifrån data från nio intervjudeltagare som arbetade på kommunen. Analysen visade att den data förvaltningarna var mest intresserad av handlade om volym, kategorier, vidarekopplingar, service och jämförelser med andra förvaltningar. Resultaten av den tematiska analysen lade även grunden för att besvara resterande två frågeställningar - “Hur bör denna information visualiseras för att den lättast ska kunna förstås och användas?” samt “Hur skulle ett gränssnitt för återkopplingsrapporten till förvaltningarna kunna se ut?”. För att besvara dessa frågeställningar presenterades tidigare forskning om hur rapporter utformas idag och teori kring existerande gestaltlagar samtidigt som det producerades en persona, kontextscenarier, en kravspecifikation samt skisser och en temporär prototyp av dashboard-karaktär.

  • 336.
    Al-Chalabi, Mona
    Linköpings universitet, Matematiska institutionen, Matematik och tillämpad matematik. Linköpings universitet, Tekniska fakulteten.
    Gymnasieelevers matematiska svårigheter att lösa linjära ekvationer och linjära ekvationssystem: En litteraturöversikt2018Självständigt arbete på grundnivå (yrkesexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Många gymnasieelever har svårt att förstå algebra, specifikt linjära ekvationer och linjära ekvationssystem, vilket hindrar deras vidare lärande i både matematik och andra ämnen.  Lärare måste därför ha en klar uppfattning om vilka dessa svårigheter är för att kunna hjälpa sina elever till förståelse och lärande av detta område i algebra. I studien undersöks forskningslitteraturens resultat om vilka dessa svårigheter är. Påvisade svårigheter som har illustrerats med exempel på elevlösningar är: brister i elevers algebraiska förkunskaper, procedurkunskaper och konceptuella kunskaper (särskilt om likhetstecken, konstanter och variabler), brister i elevers kunskaper om algebraisk syntax, samt brister i elevers hantering av de operationer som används för lösning av ekvationer och ekvationssystem, t ex hur man hanterar negativa koefficienter och konstanter och använder substitutionsmetoden.

  • 337.
    Aldred, Nick
    et al.
    1School of Marine Science and Technology, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK..
    Ekblad, Tobias
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Sensorvetenskap och Molekylfysik. Linköpings universitet, Tekniska högskolan.
    Andersson, Olof
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Sensorvetenskap och Molekylfysik. Linköpings universitet, Tekniska högskolan.
    Liedberg, Bo
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Sensorvetenskap och Molekylfysik. Linköpings universitet, Tekniska högskolan.
    Clare, Anthony C.
    1School of Marine Science and Technology, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK..
    In situ study of surface exploration by barnacle cyprids (Semibalanus balanoides) using imaging surface plasmon resonanceManuskript (preprint) (Övrigt vetenskapligt)
    Abstract [en]

    Imaging surface plasmon resonance (iSPR) was employed to investigate the interfacial adhesion phenomena that occur during the exploration of immersed surfaces by barnacle cyprids (Semibalanus balanoides). It was hypothesised that since the footprint material used by cyprids for temporary adhesion has previously been related to a large cuticular glycoprotein (SIPC), the passive deposition of cyprid footprints and the binding of SIPC to surfaces might correlate. Increased surface exploration (and footprint deposition) has also been related to increased likelihood of settlement in barnacle cyprids. If a correlation between footprint deposition and SIPC binding were to exist, therefore, there would be potential for the development of a high‐throughput assay to determine the efficacy of putative antifouling chemistries against cyprids prior to, or instead of, lengthy bio‐assays. Footprints were deposited in large numbers on carboxyl‐terminated self‐assembled monolayers (SAMs) and in very small numbers on ethylene glycol‐containing SAMs and hydrogel coatings. SIPC binding also followed the same trend. An exception to the correlation was an amineterminated SAM that accumulated few cyprid footprints, but bound SIPC strongly. It is concluded that there is great potential for the iSPR technique to be used in the evaluation of putatively non‐fouling surfaces as well as improving our understanding of the nature of the cyprid footprint material and its interactions with surfaces of different chemistry. However, the use of SIPC binding as a predictor of footprint accumulation/likelihood of settlement of cyprids to surfaces would be premature at this stage without first understanding the exceptions highlighted in this study.

  • 338.
    Aldén, Fanny
    et al.
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Medie- och Informationsteknik. Linköpings universitet, Tekniska fakulteten.
    Juopperi, Emil
    Linköpings universitet, Institutionen för teknik och naturvetenskap, Medie- och Informationsteknik. Linköpings universitet, Tekniska fakulteten.
    UX-verktyg för prototyputveckling med AI-baserat automationsstöd för omvandling av skisser till gränssnittskomponenter2018Självständigt arbete på avancerad nivå (masterexamen), 20 poäng / 30 hpStudentuppsats (Examensarbete)
    Abstract [en]

    Att skapa prototyper för att testa idéer är vanligt, oavsett vad det är som ska testas. Prototyper kan förekomma i oändligt olika former och vara mer eller mindre verklighetstrogna. Hur verklighetstrogen en prototyp är beror på vad som ska testas och hur mycket tid som läggs på prototypskapandet. I teknikbranschen är prototyperna vanligen digitala och skapas med prototypprogram. Eftersom tid är pengar så försöker företag effektivisera prototyprocessen genom att utforska nya tekniker, som exempelvis artificiell intelligens. Syftet med examensarbetet som beskrivs i den här rapporten är att undersöka hur ett prototypverktyg med automation bör utformas samt vilka eventuella användningsområde verktyget har. Under examensarbetet genomfördes intervjuer med anställda på konsultföretaget Exsitec. Syftet med intervjuerna var att ta reda på hur Exsitec arbetar med prototyper i uppstarten av sina projekt. Med hjälp av informationen identifierades svårigheter i arbetsprocessen. Utifrån den informationen utvecklades prototypverktyget ProtoDraw. Verktyget är utrustat med artificiell intelligens, som känner igen skisser och ger utifrån dem rekommendationer på webbkomponenter. Prototypverktyget utvecklades, tränades och testades som en del av fallstudien. Målet med fallstudien var att testa användares förtroende för verktyget samt hur förtroendet berodde på verktygets automationsnivå. Prototypverktyget utrustades med tre automationsnivåer interaktionsmodell A, interaktionsmodell B och interaktionsmodell C. Interaktionsmodell A gav alla förslag till användaren och rekommenderade de mest lika komponenterna genom att rama in dem. I interaktionsmodell B fick användaren endast de tre bästa resultaten. I interaktionsmodell C fick användaren endast ett förslag från automationen. Totalt genomfördes 15 användartester, fem stycken på varje nivå. Resultatet från användartesterna visade att interaktionsmodell B hade högst och stadigast förtroende. Interaktionsmodell B var även nivån som användarna ansåg var mest användbar. Trots detta var A nivån som användarna utförde uppgifterna i användartesterna på kortast tid. C hade den långsammaste tiden och det berodde på att den höga automationsnivån bidrog till att gränssnittet blev känsligt för fel.

  • 339.
    Aleckovic, Ehlimana
    et al.
    Linköpings universitet, Institutionen för fysik, kemi och biologi.
    Andersson, Linnea
    Linköpings universitet, Institutionen för fysik, kemi och biologi.
    Chamoun, Sherley
    Linköpings universitet, Institutionen för fysik, kemi och biologi.
    Einarsson, Ellen
    Linköpings universitet, Institutionen för fysik, kemi och biologi.
    Ekstedt, Ebba
    Linköpings universitet, Institutionen för fysik, kemi och biologi.
    Eriksen, Emma
    Linköpings universitet, Institutionen för fysik, kemi och biologi.
    Madan-Andersson, Maria
    Linköpings universitet, Institutionen för fysik, kemi och biologi.
    Method Development for Determining the Stability of Heat Stable Proteins Combined with Biophysical Characterization of Human Calmodulin and the Disease Associated Variant D130G2016Självständigt arbete på grundnivå (kandidatexamen), 10,5 poäng / 16 hpStudentuppsats (Examensarbete)
    Abstract [en]

    Calmodulin is a highly conserved calcium ion binding protein expressed in all eukaryotic species. The 149 amino acid residues in the primary structure are organized in seven α helices with the highly flexible central α helix connecting the two non-cooperative domains of calmodulin. Each domain contains two EF-hand motifs to which calcium ions bind in a cooperative manner, hence the binding of four calcium ions saturate one calmodulin molecule. In the cardiovascular area calmodulin is involved in the activation of cardiac muscle contraction, and mutations that arise in the genetic sequence of the protein often have severe consequences. One such consequential mutation that can arise brings about the replacement of the highly conserved aspartic acid with glycine at position 130 in the amino acid sequence. In this research, the thermal and chemical stability within the C domain of the D130G variant of human calmodulin was investigated using a new method only requiring circular dichroism spectroscopic measurements. Affinity studies within the C domain of the D130G variant of human calmodulin were performed using fluorescence spectroscopy, and the ligands chosen for this purpose were trifluoperazine and p- HTMI. All analytical experiments were performed with the C domain of wild type human calmodulin as a reference. From the new method, it was concluded that the C domain of the D130G variant of human calmodulin has a slightly decreased stability in terms of Tm and Cm values compared to the C domain of wild type human calmodulin. The affinity analyses indicated that neither trifluoperazine nor p-HTMI discriminates between the C domain of the D130G variant of human calmodulin and the C domain of wild type human calmodulin in terms of dissociation constants. The pivotal outcome from this research is that the new method is applicable for determination of the stability parameters Tm and Cm of heat stable proteins. 

  • 340. Aleksiejunas, R.
    et al.
    Jarasiunas, K.
    Kakanakova-Georgieva, Anelia
    Linköpings universitet, Tekniska högskolan. Linköpings universitet, Institutionen för fysik, kemi och biologi, Halvledarmaterial.
    Janzén, Erik
    Linköpings universitet, Tekniska högskolan. Linköpings universitet, Institutionen för fysik, kemi och biologi, Halvledarmaterial.
    Characterization of GaN/SiC epilayers by picosecond four-wave mixing technique2004Ingår i: Physica Scripta, Vol. T114, 2004, Vol. T114, s. 231-232Konferensbidrag (Refereegranskat)
  • 341.
    Alemon, B.
    et al.
    University of Guadalajara, Mexico .
    Flores, M.
    University of Guadalajara, Mexico .
    Canto, C.
    Instituto de Física, UNAM, Coyoacán, Mexico.
    Andrade, E.
    Instituto de Física, UNAM, Coyoacán, Mexico.
    de Lucio, O.G.
    Instituto de Física, UNAM, Coyoacán, Mexico.
    Rocha, M.F.
    ESIME-Z, Instituto Politécnico Nacional, Mexico.
    Broitman, Esteban
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Ion beam analysis, corrosion resistance and nanomechanical properties of TiAlCN/CNx multilayer grown by reactive magnetron sputtering2014Ingår i: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, ISSN 0168-583X, E-ISSN 1872-9584, Vol. 331, s. 134-139Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A novel TiAlCN/CNx, multilayer coating, consisting of nine TiAlCN/CNx periods with a top layer 0.5 mu m of CNx, was designed to enhance the corrosion resistance of CoCrMo biomedical alloy. The multilayers were deposited by dc and RF reactive magnetron sputtering from Ti0.5Al0.5 and C targets respectively in a N-2/Ar plasma. The corrosion resistance and mechanical properties of the multilayer coatings were analyzed and compared to CoCrMo bulk alloy. Ion beam analysis (IBA) and X-ray diffraction tests were used to measure the element composition profiles and crystalline structure of the films. Corrosion resistance was evaluated by means of potentiodynamic polarization measurements using simulated body fluid (SBF) at typical body temperature and the nanomechanical properties of the multilayer evaluated by nanoindentation tests were analyzed and compared to CoCrMo bulk alloy. It was found that the multilayer hardness and the elastic recovery are higher than the substrate of CoCrMo. Furthermore the coated substrate shows a better general corrosion resistance than that of the CoCrMo alloy alone with no observation of pitting corrosion.

  • 342.
    Alemon, B.
    et al.
    University of Guadalajara, Mexico; Tecnol Monterrey, Mexico.
    Flores, M.
    University of Guadalajara, Mexico.
    Ramirez, W.
    University of Guadalajara, Mexico.
    Huegel, J. C.
    Tecnol Monterrey, Mexico.
    Broitman, Esteban
    Linköpings universitet, Institutionen för fysik, kemi och biologi, Tunnfilmsfysik. Linköpings universitet, Tekniska högskolan.
    Tribocorrosion behavior and ions release of CoCrMo alloy coated with a TiAlVCN/CNx multilayer in simulated body fluid plus bovine serum albumin2015Ingår i: Tribology International, ISSN 0301-679X, E-ISSN 1879-2464, Vol. 81, s. 159-168Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    While the CoCrMo biomaterial is currently employed in artificial joints, there are medical concerns regarding its metal ion release and material loss caused by tribocorrosion. In this work, a TiAlVCN/CNx multilayer coating has been employed to improve the tribocorrosion-resistance of the CoCrMo substrate. During the tribocorrosion test, with the sample immersed in a simulated body fluid containing bovine serum albumin, open-circuit potential measurements showed more noble potential as well as a reduction of both the friction coefficient and wear-rate during the sliding phase. Inductive coupled plasma results demonstrate that the multilayer coating effectively blocked the emigration of metallic ions.

  • 343.
    Alenljung, Beatrice
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska högskolan.
    Decision-making in the requirements engineering process: a human-centered approach2005Licentiatavhandling, monografi (Övrigt vetenskapligt)
    Abstract [en]

    Complex decision-making is a prominent aspect of requirements engineering and the need for improved decision support for requirements engineers has been identified by a number of authors. A first step toward better decision support in requirements engineering is to understand decision-makers- complex decision situations. To gain a holistic perspective of the decision situation from a decision-makers perspective, a decision situation framework has been created. The framework evolved through a literature analysis of decision support systems and decision-making theories. The decision situation of requirements engineers has been studied at Ericsson Microwave Systems and is described in this thesis. Aspects of decision situations are decision matters, decision-making activities, and decision processes. Another aspect of decision situations is the factors that affect the decision-maker. A number of interrelated factors have been identified. Each factor consists of problems and these are related to decision-making theories. The consequences of this for requirements engineering decision support, represented as a list that consists of desirable high-level characteristics, are also discussed.

  • 344.
    Alenljung, Beatrice
    Linköpings universitet, Institutionen för datavetenskap. Linköpings universitet, Tekniska högskolan.
    Envisioning a Future Decision Support System for Requirements Engineering: A Holistic and Human-centred Perspective2008Doktorsavhandling, monografi (Övrigt vetenskapligt)
    Abstract [en]

    Complex decision-making is a prominent aspect of requirements engineering (RE) and the need for improved decision support for RE decision-makers has been identified by a number of authors in the research literature. The fundamental viewpoint that permeates this thesis is that RE decision-making can be substantially improved by RE decision support systems (REDSS) based on the actual needs of RE decision-makers as well as the actual generic human decision-making activities that take place in the RE decision processes. Thus, a first step toward better decision support in requirements engineering is to understand complex decision situations of decision-makers. In order to gain a holistic view of the decision situation from a decision-maker’s perspective, a decision situation framework has been created. The framework evolved through an analysis of decision support systems literature and decision-making theories. The decision situation of RE decision-makers has been studied at a systems engineering company and is depicted in this thesis. These situations are described in terms of, for example, RE decision matters, RE decision-making activities, and RE decision processes. Factors that affect RE decision-makers are also identified. Each factor consists of problems and difficulties. Based on the empirical findings, a number of desirable characteristics of a visionary REDSS are suggested. Examples of characteristics are to reduce the cognitive load, to support creativity and idea generation, and to support decision communication. One or more guiding principles are proposed for each characteristic and available techniques are described. The purpose of the principles and techniques is to direct further efforts concerning how to find a solution that can fulfil the characteristic. Our contributions are intended to serve as a road map that can direct the efforts of researchers addressing RE decision-making and RE decision support problems. Our intention is to widen the scope and provide new lines of thought about how decision-making in RE can be supported and improved.

  • 345.
    Alesand, Alexander
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system.
    Emulating 3G Network Characteristics on WiFi Networks2015Självständigt arbete på avancerad nivå (masterexamen), 20 poäng / 30 hpStudentuppsats (Examensarbete)
    Abstract [en]

    Mobile applications should work regardless of which type of wireless interface is used, and should be able to conceal unstable connections from the user to improve user experience. Therefore, network testing is important when developing mobile applications, but it is a challenge to reproduce network conditions when using real cellular networks since the test engineer has no control over the quality of the cellular network. Existing software tools can restrict bandwidth and add latency to the connection, but these tools do not accurately emulate cellular networks.

    This thesis proposes a system where it is possible to shape the network traffic for connected devices to mimic the network patterns of a real cellular connection when running on a WiFi connection. The design presented in this thesis is intended for testing mobile applications under diverse 3G connection parameters, such as latency, bandwidth and other characteristics.

    This thesis was conducted at Spotify, a company that provides a music streaming service which is a frequent user of network data traffic. The 3G emulator was evaluated using the Spotify Android application by measuring the correlation between packet traces from a real 3G connection and the 3G emulator. This correlation was compared to the correlation between packet traces from a real 3G connection and the current network emulator at Spotify. The evaluation shows that the proposed 3G emulator outperforms the current network emulator when performing tests on the Spotify application for Android. By using this emulator, we expect the network testing to become more effective as any 3G condition can be tested with repeatable results.

  • 346.
    Alesand, Alexander
    et al.
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Vergara, Ekhiotz Jon
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Nadjm-Tehrani, Simin
    Linköpings universitet, Institutionen för datavetenskap, Programvara och system. Linköpings universitet, Tekniska fakulteten.
    Communication Energy Evaluation for Mobile Applications: Emulating 3G over WiFi2016Ingår i: ProceedingENERGY-SIM '16 Proceedings of the 2nd International Workshop on Energy-Aware Simulation, ACM Digital Library, 2016Konferensbidrag (Refereegranskat)
    Abstract [en]

    Ubiquitous connectivity and massive use of mobile applications are currently hampered by fast battery drain of mobile devices. The communication energy of a mobile device is highly inuenced by the cellular operator conguration and the communication data pattern. Although testing the functionality and eciency of an application under diverse and realistic network settings is desirable, it is currently limited at the application developer test environment. It is generally hard to mimic di erent operator (infrastructure) settings that impact battery drain. In this paper we propose a system that creates a realistic cellular network testing environment for mobile applications on top of a WiFi network. A mobile device connects via WiFi to an emulator which shapes the uplink and downlink WiFi trac using real cellular operator conguration parameters. The system provides higher test repeatability compared to live networks and can be congured to emulate diverse cellular network parameters. These parameters, which determine the energy consumption, can be changed modularly and eciently. The evaluation of the resulting trac of the emulator compared to real cellular packet races from a streaming application shows a high correlation (0.97-0.98). The work has resulted in integration of the emulator within Spotify's test environment.

  • 347.
    Alesand, Elias
    et al.
    Linköpings universitet, Institutionen för datavetenskap.
    Sterneling, Hanna
    Linköpings universitet, Institutionen för datavetenskap.
    A shoulder-surfing resistant graphical password system2017Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [en]

    The focus of this report is to discuss graphical password systems and how they can contribute to handle security problems that threaten authentication processes. One such threat is shoulder-surfing attacks, which are also reviewed in this report. Three already existing systems that are claimed to be shoulder-surfing resilient are described and a new proposed system is presented and evaluated through a user study. Moreover, the system is compared to the mentioned existing systems to further evaluate the usability, memorability and the time it takes to authenticate. The user study shows that test subjects are able to remember their chosen password one week after having registered and signed in once. It is also shown that the average time to sign in to the system after five minutes of practice is within a range of 3.30 to 5.70 seconds. The participants in the experiments gave the system an average score above 68 on the System Usability Scale, which is the score of an average system.

  • 348.
    Alexander, Helen K.
    et al.
    Manitoba Institute of Cell Biology, and Department of Biochemistry and Medical Genetics, Univ. Manitoba, Winnipeg, Canada.
    Booy, Evan P.
    Manitoba Institute of Cell Biology, and Department of Biochemistry and Medical Genetics, Univ. Manitoba, Winnipeg, Canada.
    Xiao, Wenyan
    Cancer Care Manitoba, Manitoba Institute of Cell Biology, University of Manitoba,.
    Ezzati, Peyman
    Cancer Care Manitoba, Manitoba Institute of Cell Biology, University of Manitoba,.
    Baust, Heinrich
    Cancer Care Manitoba, Manitoba Institute of Cell Biology, University of Manitoba,.
    Los, Marek Jan
    Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Canada.
    Selected technologies to control genes and their products for experimental and clinical purposes2007Ingår i: Archivum Immunologiae et Therapiae Experimentalis, ISSN 0004-069X, Vol. 55, nr 3, s. 139-149Artikel, forskningsöversikt (Refereegranskat)
    Abstract [en]

    "On-demand" regulation of gene expression is a powerful tool to elucidate the functions of proteins and biologically-active RNAs. We describe here three different approaches to the regulation of expression or activity of genes or proteins. Promoter-based regulation of gene expression was among the most rapidly developing techniques in the 1980s and 1990s. Here we provide basic information and also some characteristics of the metallothionein-promoter-based system, the tet-off system, Muristerone-A-regulated expression through the ecdysone response element, RheoSwitch (R), coumermycin/novobiocin-regulated gene expression, chemical dimerizer-based promoter activation systems, the "Dual Drug Control" system, "constitutive androstane receptor"-based regulation of gene expression, and RU486/mifepristone-driven regulation of promoter activity. A large part of the review concentrates on the principles and usage of various RNA interference techniques (RNAi: siRNA, shRNA, and miRNA-based methods). Finally, the last part of the review deals with historically the oldest, but still widely used, methods of temperature-dependent regulation of enzymatic activity or protein stability (temperature-sensitive mutants). Due to space limitations we do not describe in detail but just mention the tet-regulated systems and also fusion-protein-based regulation of protein activity, such as estrogen-receptor fusion proteins. The information provided below is aimed to assist researchers in choosing the most appropriate method for the planned development of experimental systems with regulated expression or activity of studied proteins.

  • 349.
    Alexander, Helen K.
    et al.
    Cancer Care Manitoba, Manitoba Institute of Cell Biology, University of Manitoba.
    Booy, Evan P.
    Cancer Care Manitoba, Manitoba Institute of Cell Biology, University of Manitoba; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Canada .
    Xiao, Wenyan
    Cancer Care Manitoba, Manitoba Institute of Cell Biology, University of Manitoba.
    Ezzati, Peyman
    Cancer Care Manitoba, Manitoba Institute of Cell Biology, University of Manitoba.
    Baust, Heinrich
    Department of Radiooncology, University of Erlangen, Erlangen, Germany .
    Los, Marek Jan
    Manitoba Institute of Cell Biology, Cancer Care Manitoba; Manitoba Institute of Child Health; Department of Biochemistry and Medical Genetics; Department of Human Anatomy and Cell Science, University Manitoba, Winnipeg, Canada, .
    Selected technologies to control genes and their products for experimental and clinical purposes2007Ingår i: Archivum Immunologiae et Therapiae Experimentalis, ISSN 0004-069X, E-ISSN 1661-4917, Vol. 55, nr 3, s. 139-149Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    "On-demand" regulation of gene expression is a powerful tool to elucidate the functions of proteins and biologically-active RNAs. We describe here three different approaches to the regulation of expression or activity of genes or proteins. Promoter-based regulation of gene expression was among the most rapidly developing techniques in the 1980s and 1990s. Here we provide basic information and also some characteristics of the metallothionein-promoter-based system, the tet-off system, Muristerone-A-regulated expression through the ecdysone response element, RheoSwitch (R), coumermycin/novobiocin-regulated gene expression, chemical dimerizer-based promoter activation systems, the "Dual Drug Control" system, "constitutive androstane receptor"-based regulation of gene expression, and RU486/mifepristone-driven regulation of promoter activity. A large part of the review concentrates on the principles and usage of various RNA interference techniques (RNAi: siRNA, shRNA, and miRNA-based methods). Finally, the last part of the review deals with historically the oldest, but still widely used, methods of temperature-dependent regulation of enzymatic activity or protein stability (temperature-sensitive mutants). Due to space limitations we do not describe in detail but just mention the tet-regulated systems and also fusion-protein-based regulation of protein activity, such as estrogen-receptor fusion proteins. The information provided below is aimed to assist researchers in choosing the most appropriate method for the planned development of experimental systems with regulated expression or activity of studied proteins.

  • 350.
    Alexandersson, Henrik
    et al.
    Linköpings universitet, Institutionen för datavetenskap.
    Bouganim, Jakob
    Linköpings universitet, Institutionen för datavetenskap.
    Do Ruibin, Kevin
    Linköpings universitet, Institutionen för datavetenskap.
    Gunnarsson, Daniel
    Linköpings universitet, Institutionen för datavetenskap.
    Hyllienmark, Erik
    Linköpings universitet, Institutionen för datavetenskap.
    Karlsson, Anton
    Linköpings universitet, Institutionen för datavetenskap.
    Nathanaelsson, Sara
    Linköpings universitet, Institutionen för datavetenskap.
    Ringqvist, Hugo
    Linköpings universitet, Institutionen för datavetenskap.
    En studie kring utvecklingen av webbapplikationen HappyBox2017Självständigt arbete på grundnivå (kandidatexamen), 12 poäng / 18 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syftet med rapporten var att undersöka hur en e-­butik för matvarupaket kunde utformas och implementeras för att vara användbar avseende navigerbarhet, samtidigt som den inger förtroende hos användaren och uppmuntrar till kundengagemang. Utifrån en förstudie kartlades intresset för produkten. Därefter utvecklades en prototyp och webbapplikationens design utformades. Utvecklingen skedde genom ett iterativt arbetssätt och frågeställningens beståndsdelar testades kontinuerligt i form av användbarhetstester. Rapporten presenterar och diskuterar webbapplikationens design och hur den använts i försök att uppfylla syftet. Även tekniska lösningar avseende utformandet av webbapplikationen diskuteras och motiveras. Slutligen argumenterar rapporten för hur feedback och tydliga knappar gör webbapplikationen förtroendeingivande och navigerbar. Slutsatser kring huruvida webbapplikationen uppmuntrar till kundengagemang har varit svåra att dra och författarna har därför avstått från detta.

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