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  • 51.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Mätning och modellering av temperaturförlopp2004In: Sotning och brandskydd,2004, 2004Conference paper (Other academic)
  • 52.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Mätningar av temperatur i medicintekniska utrustningar, några fällor och fel2004In: Svenska Läkaresällskapets Riksstämma,2004, 2004Conference paper (Other academic)
  • 53.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Noggrann energimätning i villan?2004Report (Other academic)
  • 54.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Några riskfaktorer vid användning av lokaleldstäder2004In: Skorstensfejarmästaren,2004, 2004Conference paper (Other academic)
  • 55.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Temperaur i djupet2004Report (Other academic)
  • 56.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Ökensol värmer processledning?2004Report (Other academic)
  • 57.
    Loyd, Dan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Erlandsson, B-E
    Ask, Per
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Physiological Measurements.
    Computer analysis of hyperthermia treatment of the prostate1997In: Advances in Engineering Software, ISSN 0965-9978, E-ISSN 1873-5339, Vol. 28, p. 347-351Article in journal (Refereed)
  • 58.
    Loyd, Dan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Wren, Joakim
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Ekvationer för att beräkna temperaturen i vävnader2004In: Svenska Läkaresällskapets Riksstämma,2004, 2004Conference paper (Other academic)
  • 59. Nelsson, Claes
    et al.
    Forsell, Göran
    Hermansson, Patrik
    Hjelm, Annika
    Hedborg-Karlsson, Eva
    Sjöqvist, Stefan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    A database of materal properties for optical signature modelling2004Report (Other academic)
  • 60. Nelsson, Claes
    et al.
    Lindell, Roland
    Sjöqvist, Stefan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Winzell, Thomas
    Ground Truth2004Report (Other academic)
  • 61. Nilsson, Stefan
    et al.
    Hågård, Arne
    Nelsson, Claes
    Nyberg, Sten
    Persson, Rolf
    Rahm, Jonas
    Sjöqvist, Stefan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Signaturanpassning via internationelle insatser - En förstudie2004Report (Other academic)
  • 62.
    Renner, Johan
    Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics. Linköping University, The Institute of Technology.
    Estimating patient specific wall shear stress in the human aorta: geometrical and post-processing considerations2006Licentiate thesis, comprehensive summary (Other academic)
    Abstract [en]

    This thesis describes a workflow to perform in-vivo wall shear stress (WSS) estimations in the human aorta using computational fluid dynamics (CFD) methods. An abnormal WSS distribution is believed to influence the development of many cardiovascular diseases, e.g. atherosclerosis. The focus in this thesis is on geometrical influence on the WSS results and interpretation methods tor non-stationary results. The work shows that results are sensitive to the choice of segmentation method (the process from medical images to a geometrical model) and a correct geometrical description of the artery is crucial in making WSS estimations. A new parameter for non-stationary WSS results has been proposed; Wall Shear Stress Angular Amplitude (WSSAA), making the analysis of non-stationary results more straight-forward. It has been shown that the workfiow can be used with confidence and that WSS can be estimated in-vivo. using the combination of MRI-based geometry definition and CFD.

    List of papers
    1. Geometrical Considerations in Patient Specific Models of a Human Aorta with Stenosis and Aneurysm
    Open this publication in new window or tab >>Geometrical Considerations in Patient Specific Models of a Human Aorta with Stenosis and Aneurysm
    2004 (English)In: Computational Fluid Dynamics 2004: Proceedings of the Third International Conference on Computational Fluid Dynamics, ICCFD3, Toronto, 12–16 July 2004, 2004, p. 335-340Conference paper, Published paper (Refereed)
    Abstract [en]

    The most important artery in the human body is the aorta that supplies the rest of the body with blood. Lesions in the aorta can cause serious complications, which can even lead to death. How the flow is behaving in lesions, what causes the problems and which lesions are dangerous are highly interesting to determine. Laminar, stationary CFD calculations are performed on two geometrically different models of the human aorta created from the same set of patient MRI (Magnetic Resonance Imaging) data. Differences in the CFD results due to different geometries are evaluated. Overview results e.g. pressure variations throughout the artery are not dependent on an exact description of the geometry. If absolute and local values e.g. wall shear stress are sought more robust geometry creation procedure is needed in order to get more reliable results.

    Keywords
    Geometrical considertions, Human Aorta
    National Category
    Engineering and Technology
    Identifiers
    urn:nbn:se:liu:diva-23244 (URN)10.1007/3-540-31801-1_46 (DOI)2661 (Local ID)978-3-540-31800-2 (ISBN)2661 (Archive number)2661 (OAI)
    Conference
    Third International Conference on Computational Fluid Dynamics, ICCFD3, Toronto, 12–16 July 2004
    Available from: 2009-10-07 Created: 2009-10-07 Last updated: 2016-03-14
    2. Assessment of Geometrical Influence on WSS Estimation in the Human Aorta
    Open this publication in new window or tab >>Assessment of Geometrical Influence on WSS Estimation in the Human Aorta
    2006 (English)In: WSEAS Transactions on Fluid Mechanics, ISSN 1790-5087, Vol. 4, no 1, p. 318-326Article in journal (Refereed) Published
    Abstract [en]

    Computational fluid dynamics simulations were performed on a stenosed human aorta with poststenotic dilatation, in order to estimate wall shear stress (WSS). WSS is important due to its correlation with atherosclerosis. Both steady-state and non-stationary simulations were conducted. Three different models were created from a set of MRI images. Comparison of geometrically different models was accomplished by using geometrical landmarks and a comparison parameter. Geometrical differences had larger influence on WSS magnitude than inflow rotation in steady-state results for the models used. In non-stationary flow the largest differences in WSS are found when the flow velocity near the wall is low e.g. when the inflow is low or in recirculation regions.

    Keywords
    wall shear stress, human aorta, geometry influence, cfd, result, comparison
    National Category
    Engineering and Technology Radiology, Nuclear Medicine and Medical Imaging Medical Image Processing Fluid Mechanics and Acoustics
    Identifiers
    urn:nbn:se:liu:diva-37433 (URN)35727 (Local ID)35727 (Archive number)35727 (OAI)
    Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2016-03-14
    3. Post-Processing Dynamic Behavior of WSS in Aortic Blood Flow
    Open this publication in new window or tab >>Post-Processing Dynamic Behavior of WSS in Aortic Blood Flow
    2006 (English)Report (Other academic)
    Abstract [en]

    Pulsating flow simulations with CFD is performed on a stenosed human aorta with post-stenotic dilatation, for development of wall shear stress (WSS) dynamic parameters. WSS is of interest due to its correlation with atherosclerosis. The dynamic behavior and dynamic capturing parameters of WSS are usable in analyzing non-stationary results from blood flow simulations. The amount of wall back-flow is shown to be an very easy parameter to interpret and it showed an "washout" effect in the post-stenotic dilatation. A new dynamic capturing parameter describing the WSS angular amplitude (WSSAA) is presented. It has both differences and similarities with the widely used oscillating shear index (OSI) parameter. WSSA have a more direct physical interpretation then OSI.

    Place, publisher, year, edition, pages
    Linköping: Linköpings Universitetet, 2006
    Series
    LITH-IKP-R, ISSN 0281-5001 ; 6
    Keywords
    WallShear Stress, Human Aorta, CFD, WSS angular amplitude, Wall back-flow
    National Category
    Engineering and Technology
    Identifiers
    urn:nbn:se:liu:diva-36744 (URN)LITH-IKP-R--06/1417--SE (ISRN)32311 (Local ID)32311 (Archive number)32311 (OAI)
    Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2016-03-14
    4. Feasibility of Patient Specific Aortic Blood Flow CFD Simulation
    Open this publication in new window or tab >>Feasibility of Patient Specific Aortic Blood Flow CFD Simulation
    Show others...
    2006 (English)In: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006: 9th International Conference, Copenhagen, Denmark, October 1-6, 2006. Proceedings, Part I / [ed] Rasmus Larsen, Mads Nielsen and Jon Sporring, Springer Berlin/Heidelberg, 2006, 1, Vol. 4190, p. 257-263Conference paper, Published paper (Refereed)
    Abstract [en]

    Patient specific modelling of the blood flow through the human aorta is performed using computational fluid dynamics (CFD) and magnetic resonance imaging (MRI). Velocity patterns are compared between computer simulations and measurements. The workflow includes several steps: MRI measurement to obtain both geometry and velocity, an automatic levelset segmentation followed by meshing of the geometrical model and CFD setup to perform the simulations follwed by the actual simulations. The computational results agree well with the measured data.

    Place, publisher, year, edition, pages
    Springer Berlin/Heidelberg, 2006 Edition: 1
    Series
    Lecture Notes in Computer Science, ISSN 0302-9743, E-ISSN 1611-3349 ; 4190
    National Category
    Medical Image Processing
    Identifiers
    urn:nbn:se:liu:diva-36902 (URN)10.1007/11866565_32 (DOI)000241556300032 ()32988 (Local ID)3-5404-4707-5 (ISBN)978-3-540-44727-6 (ISBN)978-3-540-44707-8 (ISBN)32988 (Archive number)32988 (OAI)
    Conference
    The 9th MICCAI Conference, Copenhagen, Denmark, 1-6 October 2006
    Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2018-02-20Bibliographically approved
  • 63.
    Renner, Johan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Gårdhagen, Roland
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Heiberg, Einar
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Clinical Physiology.
    Ebbers, Tino
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care.
    Länne, Toste
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Physiology. Östergötlands Läns Landsting, Heart Centre, Department of Thoracic and Vascular Surgery.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Validation of Simulated Velocity of Blood in Patient Specific Aorta2006In: VIII Svenska Kardiovaskulära Vårmöte,2006, Linköping, Sweden: Linköpings universitet , 2006Conference paper (Refereed)
  • 64.
    Sjöqvist, Stefan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Abrahamson, S
    Andersson, P
    Chevalier, T
    Forssell, G
    Grönvall, C
    Larsson, H
    Letalick, D
    Linderhed, A
    Menning, D
    Nyberg, S
    Renhorn, I
    Severin, M
    Steinvall, O
    Tolt, G
    Uppsäll, M
    MOMS Multi Optical Mine Detection System, Initial report2005Report (Other academic)
  • 65.
    Sjöqvist, Stefan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Linderhed, Anna
    Nyberg, Sten
    Uppsäll, Magnus
    Temporal Method for IR Minefield Feature Detection2004In: Progress in biomedical optics and imaging, ISSN 1605-7422, Vol. 5415, p. 175-186Article in journal (Other academic)
    Abstract [en]

      

  • 66.
    Sjöqvist, Stefan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Linderhed, Anna
    Nyberg, Sten
    Uppsäll, Magnus
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Land mine detection by IR temporal analysis; physical numerical modeling2005In: SPIE defence and security symposium,2005, Orlando, Florida, USA: SPIE the international society for optical engineering , 2005Conference paper (Refereed)
  • 67.
    Stenudd, Stefan
    Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics. Linköping University, Department of Mechanical Engineering, Carl Malmsten Centre for Wood Technology and Design. Linköping University, The Institute of Technology.
    On colour changes during kiln drying of hardwood: with special reference to beech and birch2002Licentiate thesis, comprehensive summary (Other academic)
    Abstract [en]

    Kiln drying is a key factor for the utilisation of our hardwood forest resources, providing our industry with high quality raw material. The increased use of transparent surface treatment in the furniture and carpentry industries during the last decades has put an increased focus on wood colour. Fashion trends in furniture and interior design call for blond colours on our Scandinavian woods species. While commonly recognised as a major colour-controlling process in wood utilisation a fundamental understanding of how the drying procedures affect the final colour of the wood is still lacking.

    This thesis is an attempt to increase knowledge of how different process parameters during kiln drying affect the final colour of the common hardwoods beech and birch. The investigation is based on experimental dryings in climate chamber and laboratory kilns using designed factorial experiments.

    During the capillary drying phase, time is more important than temperature level for the final colour. Speedy drying even at moderately increased temperature levels results in brighter more yellowish colours. Diffusive drying from approximately the fibre saturation point to 20 % moisture content seems to be the most important colouring phase in conventional drying. Temperature and the time a local section of wood spends in the moisture content region are decisive for the final colour. To create blond wood the temperature should be kept low and the drying fast, which calls for low relative humidity levels and high air speeds.

    The common problem of grey-stain in non-steamed natural beech is caused by to slow air- or kiln drying using high relative humidity levels in the initial stages of the drying process. The problem may be avoided by increasing the speed of drying. Log storage at a low temperature during wintertime on the other hand seems to have little effect on the final colour of natural beech only affecting the hue. Winter storage of logs is thereby not a high priority issue regarding final colour of beech wood.

  • 68. Storck, K
    et al.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Ask, Per
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Physiological Measurements.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Heat transfer simulation in the evaluation of the nasal thermistor technique1996In: IEEE Transactions on Biomedical Engineering, ISSN 0018-9294, E-ISSN 1558-2531, Vol. 43, p. 1187-1191Article in journal (Refereed)
  • 69. Sun, Y
    et al.
    Ask, Per
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Physiological Measurements.
    Janerot-Sjöberg, Birgitta
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Clinical Physiology. Östergötlands Läns Landsting, Heart Centre, Department of Clinical Physiology.
    Eidenvall, Lars
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Physiological Measurements.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Wranne, Bengt
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Clinical Physiology. Östergötlands Läns Landsting, Heart Centre, Department of Clinical Physiology.
    Estimation of pulsatile flow by surface integration of velocity vectors in Doppler ultrasound images from two arthogonal planes1995In: Journal of the American Society of Echocardiography, ISSN 0894-7317, E-ISSN 1097-6795, Vol. 8, p. 904-914Article in journal (Refereed)
  • 70. Sun, Y
    et al.
    Janerot-Sjöberg, Birgitta
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Clinical Physiology. Östergötlands Läns Landsting, Heart Centre, Department of Clinical Physiology.
    Ask, Per
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Physiological Measurements.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Wranne, Bengt
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Clinical Physiology. Östergötlands Läns Landsting, Heart Centre, Department of Clinical Physiology.
    Mathematical model that characterizes transmitral and pulmonary venous flow velocity patterns1995In: American journal of physiology, ISSN 0002-9513, Vol. 268, p. 476-489Article in journal (Refereed)
  • 71. Svensson, J.
    et al.
    Gårdhagen, Roland
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, M.
    Assessment of Geometrical Influence on WSS Estimation in the Human Aorta2006In: WSEAS Transactions on Fluid Mechanics, 2006, Vol. 1Conference paper (Refereed)
    Abstract [en]

    Computational fluid dynamics simulations were performed on a stenosed human aorta with poststenotic dilatation, in order to estimate wall shear stress (WSS). WSS is important due to its correlation with atherosclerosis. Both steady-state and non-stationary simulations were conducted. Three different models were created from a set of MRI images. Comparison of geometrically different models was accomplished by using geometrical landmarks and a comparison parameter. Geometrical differences had larger influence on WSS magnitude than inflow rotation in steady-state results for the models used. In non-stationary flow the largest differences in WSS are found when the flow velocity near the wall is low e.g. when the inflow is low or in recirculation regions.

  • 72.
    Svensson, Johan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Gårdhagen, Roland
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Comparison of flow parameters between different geometries of a human aorta with coarctation and aneurysm2005In: 2005 Summer Bioengineering Conference,2005, Vail, USA: Summer Bioengineering Conference Committee , 2005Conference paper (Refereed)
  • 73.
    Svensson, Johan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Gårdhagen, Roland
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Geometrical Influence on CFD Analysis of Human Aorta2004Report (Other academic)
  • 74.
    Svensson, Johan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Gårdhagen, Roland
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Patient Specific Human Aorta Geometry Influence on CFD Simulation Parameters2004In: 17th Nordic Seminar on Computational Mechanics NSCM17,2004, 2004Conference paper (Refereed)
  • 75.
    Svensson, Johan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Gårdhagen, Roland
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Wall Back Flow Variations During Pulsative Flow in a Human Aorta2005In: Svenska Mekanikdagar 2005,2005, 2005, p. 61-62Conference paper (Refereed)
  • 76.
    Svensson, Johan
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Gårdhagen, Roland
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Wall back flow in human aorta: influence of geometry2005In: NBC05 Umeå,2005, Umeå: Int'l federation for medical anc Biological Engineering IFMBE , 2005, p. 85-Conference paper (Refereed)
  • 77.
    Svensson (Renner), Johan
    et al.
    Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics. Linköping University, The Institute of Technology. Linköping University, Center for Medical Image Science and Visualization (CMIV).
    Gårdhagen, Roland
    Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics. Linköping University, The Institute of Technology. Linköping University, Center for Medical Image Science and Visualization (CMIV).
    Heiberg, Einar
    Department of Clinical Physiology, Lund University, Sweden.
    Ebbers, Tino
    Linköping University, Department of Medicine and Care. Linköping University, Faculty of Health Sciences. Linköping University, Center for Medical Image Science and Visualization (CMIV).
    Loyd, Dan
    Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics. Linköping University, The Institute of Technology.
    Länne, Toste
    Linköping University, Department of Medicine and Care, Physiology. Linköping University, Faculty of Health Sciences. Linköping University, Center for Medical Image Science and Visualization (CMIV). Östergötlands Läns Landsting, Heart Centre, Department of Thoracic and Vascular Surgery.
    Karlsson, Matts
    Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation. Linköping University, The Institute of Technology. Linköping University, Center for Medical Image Science and Visualization (CMIV).
    Feasibility of Patient Specific Aortic Blood Flow CFD Simulation2006In: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006: 9th International Conference, Copenhagen, Denmark, October 1-6, 2006. Proceedings, Part I / [ed] Rasmus Larsen, Mads Nielsen and Jon Sporring, Springer Berlin/Heidelberg, 2006, 1, Vol. 4190, p. 257-263Conference paper (Refereed)
    Abstract [en]

    Patient specific modelling of the blood flow through the human aorta is performed using computational fluid dynamics (CFD) and magnetic resonance imaging (MRI). Velocity patterns are compared between computer simulations and measurements. The workflow includes several steps: MRI measurement to obtain both geometry and velocity, an automatic levelset segmentation followed by meshing of the geometrical model and CFD setup to perform the simulations follwed by the actual simulations. The computational results agree well with the measured data.

  • 78.
    Wren, Joakim
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Evaluation of three temperature measurement methods used during microwave thermotherapy of prostatic enlargement2004In: International Journal of Hyperthermia, ISSN 0265-6736, E-ISSN 1464-5157, Vol. 20, no 3, p. 300-316Article in journal (Refereed)
    Abstract [en]

    Three temperature measurement methods used during microwave thermotherapy of prostatic enlargement are analysed and evaluated using a phantom model. A commercial transurethral microwave thermotherapy (TUMT) system that uses a radiometric thermometer for temperature control was used to heat the phantom. The transient temperature distribution was obtained by using both fibreoptic (which is considered as gold standard) and thermocouple measurements. Both methods are subject to potential measurement errors caused by electro-magnetic and/or thermal interference. The error sources are analysed and the measurement methods evaluated. The radiometric temperature and especially its relation to the transient temperature distribution was evaluated based on the fibreoptic and thermocouple measurements. These measurements in principle gave equivalent temperature distributions, and thermal interference was concluded to be the largest source of measurement error. The radiometric measurement method gave qualitative rather than quantitative readings of the temperature, and an underestimation of more than 10°C was obtained for some parts of the heated area. The area that gives most of the radiometric signal was relatively close to the catheter in contrast to previously published results.

  • 79.
    Wren, Joakim
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Microwave Thermotherapy of Prostatic Enlargement, Analysis of Radiometric Thermometry using a Hybrid Bio-Heat Equation2004In: Computer Methods in Biomechanics and Biomedical Engineering, ISSN 1025-5842, E-ISSN 1476-8259, Vol. 7, no 3Article in journal (Refereed)
  • 80.
    Wren, Joakim
    Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics. Linköping University, The Institute of Technology.
    On modelling and simulation of perfused tissue during thermal treatment: thermal analysis of blood perfusion and lesioning during ablative neurosurgery2000Licentiate thesis, comprehensive summary (Other academic)
    Abstract [en]

    Thermal treatment means therapy for which heat is the therapeutic agent. During treatment, the tissue temperature is increased to an injurious temperature (higher than 43 °C for the most widely used treatments). The aim is to reach necrotic temperature in the treatment area and non-lethal temperature outside the same. However, for several reasons this is not possible.

    The thesis deals with thermal treatment from a thermal point of view. The principle aim of the analysis is to obtain the entire temperature field in the treatment area, preferably before the treatment even takes place (temperature prediction). However, it is a complex task to obtain the entire temperature fields which usually varies substantially with both time and space. Parameters of importance are for instance the power supply needed for a certain treatment, the blood perfusion and the heat flux within the treatment area.

    The thesis comprises two different projects; the first project regards modelling and simulation of heat transfer in blood-perfused tissue. The second project concerns modelling and simulation of lesion growth and associated thermal problems during ablative neurosurgery. Throughout the thesis the focus is on modelling, but also experiments are carried out in order to enhance the thermal analysis in the second project.

    In the first project, an important aim is to increase the understanding about the equations (bio-heat equations, BHE's) used for modelling the effect from blood perfusion. A survey as well as a discussion of the equations used the last few decades is carried out. The core of the project is to the BHE's that are variants of the heat conduction equation, and therefore easily implemented in standard thermal simulation packages. An alternative model is proposed in the thesis as a more accurate and flexible tool compared with the most widely used models, the BHE of Pennes and the keff equation.

    In the second project, the focus is on the lesion growth together with the very important temperature measurement, which is used to monitor and control the lesioning process. A simulation model is developed by using input from the in vitro experiments. The model is considered to accurately describe the lesioning process, and very good agreement between experiments and simulations is obtained.

    Furthermore, simulations are used to analyse and evaluate the intra-electrode temperature measurement. The maximum temperature was always located outside the electrode, and therefore, there is always a difference in both time and level between the measured temperature and maximum temperature in the treatment area. The difference is important to quantify, since the lesioning process is directly dependent on the temperature measurement.

  • 81.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Erlandsson, B-E
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Simulation of thermal treatment of the prostate using a hybrid bio-heat equation2001In: International Symposium on Computer Methods in Biomechanics and Biomedical Engineering,2001, 2001Conference paper (Refereed)
  • 82.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation.
    heat transfer analysis model of microwave thermal therapy of the prostate2000In: World Congress on Medical Physics and Biomedical Engineering,2000, 2000Conference paper (Refereed)
  • 83.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    A hybrid equation for simulation of perfused tissue during thermal treatment2001In: International Journal of Hyperthermia, ISSN 0265-6736, E-ISSN 1464-5157, Vol. 17, no 6, p. 483-498Article in journal (Refereed)
    Abstract [en]

    Bio-heat equations (BHEs) are necessary for predicting tissue temperature during thermal treatment. For some applications, however, existing BHEs describe the convective heat transfer by the blood perfusion in an unsatisfactory way. The two most frequently used equations, the BHE of Pennes and the keff equation, use for instance either a heat sink or an increased thermal conductivity in order to account for the blood perfusion. Both these methods introduce modelling inaccuracies when applied to an ordinary tissue continuum with a variety of vessel sizes. In this study, a hybrid equation that includes both an increased thermal conductivity and a heat sink is proposed. The equation relies on the different thermal characteristics associated with small, intermediate and large sized vessels together with the possibilities of modelling these vessels using an effective thermal conductivity in combination with a heat sink. The relative importance of these two terms is accounted for by a coefficient ▀. For ▀ = 0 and ▀ = 1, the hybrid equation coincides with the BHE of Pennes and the keff equation, respectively. The hybrid equation is used here in order to simulate temperature fields for two tissue models. The temperature field is greatly affected by ▀, and the effect is dependent on, e.g. the boundary conditions and the power supply. Since the BHE of Pennes and the keff equation are included in the hybrid equation, this equation can also be useful for evaluation of the included equations. Both these heat transfer modes are included in the proposed equation, which enables implementation in standard thermal simulation programmes.

  • 84.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Transient temperature response of the myocardium investigated by the hybrid bioheat model2004In: IASME Transactions, ISSN 1790-031X, Vol. 1, no 3, p. 560-565Article in journal (Refereed)
  • 85.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, Department of Management and Engineering, Applied Thermodynamics and Fluid Mechanics . Linköping University, The Institute of Technology.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Sjödin, Jörgen
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Energy Systems.
    Erlandsson, B-E
    A Heat Transfer Analysis of Microwave Thermal Therapy of the Prostate2000In: Annual International Conference of the IEEE Engineering in Medicine biology Society,2000, 2000Conference paper (Other academic)
  • 86.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Karlsson, Matts
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Modelling and Simulation .
    Investigation of medical thermal treatment using a hybrid bio-heat model2004In: 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society,2004, 2004Conference paper (Refereed)
  • 87.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Persson, Peter
    IKP .
    A method for determination of intra-valve heat transfer in thermostatic mixing valves2006In: International Conference on Heat and Mass Transfer,2006, Miami, Florida, USA: WSEAS/IASME , 2006, p. 46-Conference paper (Refereed)
    Abstract [en]

      

  • 88.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Persson, Peter
    IKP .
    Thermostatic mixing valves - A method for non-disturbing intra-valve heat transfer estimation2006In: Journal of Advanced Nursing, ISSN 0309-2402, E-ISSN 1365-2648, Vol. 1, p. 59-64Article in journal (Refereed)
    Abstract [en]

      

  • 89.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Persson, Peter
    IKP .
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Thermostatic Mixing Valves - Modeling and simulation of the thermostat under real operating conditions2006In: WSEAS Transactions on Circuits and Systems, ISSN 1109-2734, Vol. 1, p. 56-61Article in journal (Refereed)
    Abstract [en]

       

  • 90.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Persson, Peter
    IKP .
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Thermostatic Mixing Valves - Thermostatic temperature distribution during various operating conditions2006In: International Conference on Heat and Mass Transfer,2006, Miami, Florida, Usa: WSEAS/IASME , 2006, p. 42-Conference paper (Refereed)
    Abstract [en]

      

  • 91.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Sjödin, Jan-Gunnar
    Erlandsson, Björn-Erik
    Eliasson, Tomas
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Accuracy of Temperature Measurement During Transurethral Hyperthermia Treatment och the Prostate1999In: Proc of BMES/BMBS99,1999, 1999Conference paper (Other academic)
  • 92.
    Wren, Joakim
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Svensson, Johan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Gårdhagen, Roland
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Engstrand, Ulf
    Learning more with demonstration based education2005In: CUL-dagen 2005,2005, 2005Conference paper (Other academic)
  • 93. Xiong, C
    et al.
    Hök, Bertil
    Strömberg, Tomas
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation.
    Loyd, Dan
    Linköping University, The Institute of Technology. Linköping University, Department of Mechanical Engineering, Applied Thermodynamics and Fluid Mechanics.
    Wranne, Bengt
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Medicine and Care, Clinical Physiology. Östergötlands Läns Landsting, Heart Centre, Department of Clinical Physiology.
    Ask, Per
    Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Physiological Measurements.
    A bioacoustic method for timing of respiration at cardiac investigations1995In: Clinical Physiology, ISSN 0144-5979, E-ISSN 1365-2281, Vol. 15, p. 151-157Article in journal (Refereed)
12 51 - 93 of 93
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