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  • 51.
    Persliden, Jan
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Patient and staff doses in interventional X-ray procedures in Sweden2005Ingår i: Radiation Protection Dosimetry, ISSN 0144-8420, E-ISSN 1742-3406, Vol. 114, nr 1-3, s. 150-157Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Interventional procedures in radiology are of concern because of irradiation doses to the patients and also to the staff. A questionnaire sent to all radiology departments in Sweden showed that 11,350 procedures were performed annually 1996-1997. In a follow-up study, data from patient procedures were recorded. Type of procedure, dose-area product (DAP) values, fluoroscopy times, number of radiography series and patient data were recorded. For some procedures, staff doses were measured. Skin doses to the patients were also calculated where possible. Results: A total of 380 interventional procedures were described. The procedures were grouped into cranial, neck and thorax, intestine and abdominal, uro/genital and pelvis and extremities. DAP and fluoroscopy times (mean values) were 200 Gy cm2 for 57 min, 57 Gy cm2 for 16 min, 270 Gy cm2 for 35 min, 212 Gy cm2 for 37 min, 67 Gy cm2 for 21 min, respectively, for the named procedures. Maximum patient skin doses exceeded threshold values for erythema (2 Gy) in cranial, neck/thorax and intestine/abdominal procedures. Effective doses to the patients could be high, 200 mSv. Conclusion: It was found that patient doses could exceed threshold values for skin erythema (2 Gy) and temporary epilation (3 Gy). Hence, the procedures require immediate improvement. © The Author 2005. Published by Oxford University Press. All rights reserved.

  • 52.
    Persliden, Jan
    et al.
    Linköpings universitet, Institutionen för medicin och vård, Radiofysik. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Helmrot, Ebba
    Ryhov Hospital.
    Hjort, Per
    Ryhov Hospital.
    Resjö, Margareta
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Dose and image quality in the comparison of analogue and digital techniques in paediatric urology examinations.2004Ingår i: European Radiology, ISSN 0938-7994, E-ISSN 1432-1084, Vol. 14, nr 4, s. 638-644Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    In paediatric radiology it has been recognised that children have a higher risk of developing cancer from the irradiation than adults (two to three times); therefore, increased attention has been directed towards the dose to the patient. In this study the effect on patient dose and image quality in replacing the exposure in micturating cystourethrography (MCUG) examinations with the stored fluoroscopy image has been investigated. In the intravenous urography (IVU) examination we compared analogue and digital image quality, but the dose measurements were performed on a phantom. Standard clinical X-ray equipment was used. Sixty-eight patients in each of two centres were studied for the MCUG. Doses were measured with a dose-area product (DAP) meter and the image quality was scored. A non-parametric statistical analysis was performed. For the IVU, a phantom was used in the dose measurements but clinical images were scored in the comparison between analogue and digital images. For the MCUG, replacing the exposure with stored fluoroscopy images lowered the DAP value from 0.77 to 0.50 Gy cm2. The image quality did not show any difference between the techniques; however, if reflux was to be graded, exposure was needed. For the IVU, the doses could be lowered by a factor of 3 using digital techniques. The image quality showed no statistical difference between the two techniques. There is a potential for a substantial dose reduction in both MUCG and IVU examinations using digital techniques.

  • 53.
    Persson, Anders
    et al.
    Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiologi. Östergötlands Läns Landsting, Bildmedicinskt centrum, Röntgenkliniken i Linköping.
    Dahlström, Nils
    Department of Radiology, Hudiksvall Hospital, Sweden.
    Smedby, Örjan
    Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Diagnostikcentrum, Röntgenkliniken i Linköping.
    Brismar, T.B.
    Department of Radiology, Karolinska University Hospital, Huddinge, Stockholm, Sweden .
    Volume rendering of three-dimensional drip infusion CT cholangiography in patients with suspected obstructive biliary disease: a retrospective study2005Ingår i: British Journal of Radiology, ISSN 0007-1285, E-ISSN 1748-880X, Vol. 78, nr 936, s. 1078-1085Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The purpose of this study was to evaluate the diagnostic potential of prolonged drip infusion CT cholangiography (DIC-CT) using meglumine iotroxate (Biliscopin®) and 3D volume rendering in patients with suspected obstructive biliary disease. From a material of 142 patients who had undergone a drip infusion CT, all cases with a verified surgical or endoscopic retrograde cholangiography (ERC) diagnosis (n=33) were selected. Age-matched controls were selected from the remaining examinations. Three radiologists reviewed all 66 examinations in retrospect, independently as well as in consensus. The image quality and the estimated diagnostic quality were rated as good or moderate in 91% of the 198 reviews. The consensus sensitivity and specificity for diagnosing biliary stones was 88% and 94%, respectively (with sensitivities ranging from 88% to 94% for individual observers, and specificities from 86% to 96%). Two out of three strictures were observed. No false positive strictures were described. The use of volume rendering technique (VRT) improved diagnostic certainty in 28/198 (14%) of the evaluations. The visualization of ductal stones was improved in 18/48 (38%). No differences in diagnostic quality between single and multislice CT were observed. We conclude that a detailed image of the biliary tree with good sensitivity and specificity can be obtained by means of bilirubin-governed infusion time DIC-CT with volume rendering reconstruction.

  • 54.
    Ragnehed, Mattias
    et al.
    Linköpings universitet, Institutionen för medicin och vård, Radiologi. Linköpings universitet, Hälsouniversitetet.
    Engström, Maria
    Linköpings universitet, Institutionen för medicin och vård, Centrum för medicinsk bildvetenskap och visualisering. Linköpings universitet, Hälsouniversitetet.
    Knutsson, Hans
    Linköpings universitet, Institutionen för medicinsk teknik. Linköpings universitet, Hälsouniversitetet.
    Lundberg, Peter
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Söderfeldt, Birgitta
    Linköpings universitet, Institutionen för nervsystem och rörelseorgan. Linköpings universitet, Hälsouniversitetet.
    Performance of canonical correlation analysis in language tests by functional MRIManuskript (preprint) (Övrigt vetenskapligt)
    Abstract [en]

    In this paper a new method based on constraitwd canonical correlation analysis (CCA) for the analysis of fMRI data is evaluated. In particular the method benefits from a powerful way of choosing temporal basis functions in additiou to an adaptive spatial filtering scheme. A modified receiver operating characteristic (ROC) method was used to quantify the results and to compare it with traditionally used statistics in an objective way. The evaluation was performed using real fMRI data form a language test. It was shown that the CCA based method offers a significant gain in detection power.

  • 55.
    Ragnehed, Mattias
    et al.
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiologi. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Håkansson, Irene
    Nilsson, Maritha
    Lundberg, Peter
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Söderfeldt, Birgitta
    Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Engström, Maria
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiologi. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Influence of Diazepam on clinically designed fMRI2006Ingår i: American Neuropsyciatric Association annual meeting,2006, 2006Konferensbidrag (Övrigt vetenskapligt)
  • 56.
    Roberg, Karin
    et al.
    Linköpings universitet, Institutionen för nervsystem och rörelseorgan, Oto-Rhino-Laryngologi. Linköpings universitet, Hälsouniversitetet.
    Jonsson, Ann-Charlotte
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Grénman, Reidar
    Department of Otorhinolaryngology, Head and Neck Surgery, Central Hospital and University of Turku and Medical Biochemistry, University of Turku, Finland.
    Norberg-Spaak, Lena
    Linköpings universitet, Institutionen för nervsystem och rörelseorgan, Oto-Rhino-Laryngologi. Linköpings universitet, Hälsouniversitetet.
    Radiotherapy response in oral squamous carcinoma cell lines: Evaluation of apoptotic proteins as prognostic factors2007Ingår i: Head and Neck, ISSN 1043-3074, E-ISSN 1097-0347, Vol. 29, nr 4, s. 325-334Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background. In this study, we investigated the importance of apoptosis for cell death after radiotherapy, and whether the expression of pro- and anti-apoptotic proteins has any correlation to the radiosensitivity.

    Methods. Three oral squamous cell carcinoma cell lines, UT-SCC-2, UT-SCC-9 and UT-SCC-24A, were subjected to radiotherapy. After irradiation, viable and dead cells were counted to determine radiation sensitivity and apoptosis was analyzed by measurement of caspase-3 activity. The expressions of pro- and anti-apoptotic proteins were assessed using western blot analyses.

    Results and Conclusion. After irradiation, apoptotic morphology and caspase-3 activity were only detected in cell lines exhibiting high or moderate radiosensitivity. Western blot analysis indicates that survivin, epidermal growth factor receptor, cyclooxygenase-2, and Bcl-xL are critical components in irradiation resistance of the investigated cell lines. Moreover, our results suggest that apoptotic cell death and the balance between pro- and anti-apoptotic proteins are of importance for the outcome of radiotherapy.

  • 57.
    Rydell, Joakim
    et al.
    Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Borga, Magnus
    Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Lundberg, Peter
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Tekniska högskolan. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Knutsson, Hans
    Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Dimensionality and degrees of freedom in fMRI data analysis - a comparative study2004Ingår i: Biomedical Imaging: Nano to Macro, 2004. IEEE International Symposium on, IEEE , 2004, s. 988-991 vol.1Konferensbidrag (Refereegranskat)
    Abstract [en]

    Two- and three-dimensional isotropic and anisotropic spatial filters for adaptive fMRI data analysis are compared in terms of activation detection sensitivity and specificity. Evaluations using both real and artificial data are presented. It is shown that three-dimensional anisotropic filters provide superior activation detection performance.

  • 58.
    Rydell, Joakim
    et al.
    Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Borga, Magnus
    Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Lundberg, Peter
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Knutsson, Hans
    Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV.
    Dimensionality and number of parameters in adaptive filtering of fMRI data2004Ingår i: Proceedings of the Swedish Symposium on Image Analysis (2004), 2004, s. 90-93Konferensbidrag (Övrigt vetenskapligt)
  • 59.
    Rydell, Joakim
    et al.
    Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan.
    Knutsson, Hans
    Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan.
    Pettersson, Johanna
    Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan.
    Johansson, Andreas
    Linköpings universitet, Institutionen för medicinsk teknik. Linköpings universitet, Tekniska högskolan.
    Farnebäck, Gunnar
    Linköpings universitet, Institutionen för medicinsk teknik. Linköpings universitet, Tekniska högskolan.
    Dahlqvist Leinhard, Olof
    Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Lundberg, Peter
    Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiologi. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Bildmedicinskt centrum, Röntgenkliniken i Linköping. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Nyström, Fredrik
    Linköpings universitet, Institutionen för medicin och hälsa, Internmedicin. Linköpings universitet, Hälsouniversitetet.
    Borga, Magnus
    Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Linköpings universitet, Institutionen för medicinsk teknik, Medicinsk informatik. Linköpings universitet, Tekniska högskolan.
    Phase Sensitive Reconstruction for Water/Fat Separation in MR Imaging Using Inverse Gradient2007Ingår i: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007. 10th International Conference, Brisbane, Australia, October 29 - November 2, 2007, Proceedings, Part I / [ed] Nicholas Ayache, Sebastien Ourselin and Anthony Maeder, Springer Berlin/Heidelberg, 2007, s. 210-218Konferensbidrag (Refereegranskat)
    Abstract [en]

    This paper presents a novel method for phase unwrapping for phase sensitive reconstruction in MR imaging. The unwrapped phase is obtained by integrating the phase gradient by solving a Poisson equation. An efficient solver, which has been made publicly available, is used to solve the equation. The proposed method is demonstrated on a fat quantification MRI task that is a part of a prospective study of fat accumulation. The method is compared to a phase unwrapping method based on region growing. Results indicate that the proposed method provides more robust unwrapping. Unlike region growing methods, the proposed method is also straight-forward to implement in 3D.

  • 60.
    Salerud, Göran
    et al.
    Linköpings universitet, Tekniska högskolan. Linköpings universitet, Institutionen för medicinsk teknik, Biomedicinsk instrumentteknik.
    Gunnarsson, S.
    Lund, Eva
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Problem Based Learning (PBL) and cirricula redesign in BioMedical Engineering (BME) in the framework of Concieve Design Implement and Operate (CDIO) initiative2005Ingår i: Biomedical Engineering Educational Summit meeting,2005, 2005Konferensbidrag (Övrigt vetenskapligt)
  • 61.
    Salerud, Göran
    et al.
    Linköpings universitet, Tekniska högskolan. Linköpings universitet, Institutionen för medicinsk teknik, Biomedicinsk instrumentteknik.
    Lund, Eva
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Multiprofessional education in Biomedical Engineering using PBL2000Ingår i: Int Academy Medical and Biological Engineering. Workshop on Biomedical Engineering Education.,2000, 2000Konferensbidrag (Övrigt vetenskapligt)
  • 62.
    Salerud, Göran
    et al.
    Linköpings universitet, Tekniska högskolan. Linköpings universitet, Institutionen för medicinsk teknik, Biomedicinsk instrumentteknik.
    Lund, Eva
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Multiprofessional education in Biomedical Engineering with individual learning documents for students evaluation and assessment2000Ingår i: Biomedical Engineering Educational Summit meeting,,2000, 2000Konferensbidrag (Övrigt vetenskapligt)
    Abstract [en]

      

  • 63.
    Sandborg, Michael
    et al.
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Abramowicz, JS
    Lewis, V
    Plain Radiography and Fluoroscopy1999Ingår i: Gynecological Imaging, London: Elsevier Health Sciences , 1999, s. 19-30Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 64.
    Sandborg, Michael
    et al.
    Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen. Linköpings universitet, Hälsouniversitetet.
    Carlsson, C. A.
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Alm Carlsson, Gudrun
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Shaping X-ray spectra with filters in X-ray diagnostics1994Ingår i: Medical and Biological Engineering and Computing, ISSN 0140-0118, E-ISSN 1741-0444, Vol. 32, nr 4, s. 384-390Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The influence on image contrast, tube load and patient mean absorbed dose of different ways of shaping diagnostic X-ray spectra by placing filters in the beam is derived for two radiographic models (abdominal screen-film radiography and intra-oral, dental radiography) using a computational model. The filters are compared at either equal tube load (keeping tube potential constant) or equal contrast (adjusting the tube potential with the different filters), but always at equal energy imparted per unit area to the image receptor. Compared at equal tube load and relative to standard aluminium filtration, reductions in the mean absorbed dose in the patient of 15–25% can be achieved using filters of Cu, Ti, W and Au (increasing the tube load by 30–40% compared with standard aluminium filtration). However, contrast is also reduced by 7%. Compared at equal contrast, the dose reductions are smaller, about 10%. Filters of copper are generally recommended, as are filters of aluminium. The use of bandpass filters (K-edge filters) should be restricted to examinations where the need for substantial variation in tube potential from patient to patient is small. The benefit of using thicker filters than those commonly used today (increasing tube load by factors of 1.4–2.0 compared with no added filter) is small as the dose reduction is most rapid for small initial values of added filters, and the increase in tube load increases steadily with increasing filter thickness.

  • 65.
    Sandborg, Michael
    et al.
    Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen. Linköpings universitet, Hälsouniversitetet.
    Christoffersson, Jan-Ove
    n/a.
    Alm Carlsson, Gudrun
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Almen, Torsten
    n/a.
    Dunce, D A
    n/a.
    The physical performance of different x-ray contrast agents: calculations using a Monte Carlo model of the imaging chain1995Ingår i: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 40, nr 7, s. 1209-1224Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A Monte Carlo computational model of the imaging chain has been used to investigate the performance of X-ray contrast agents with atomic number, Z, 53<or=Z<or=90 with respect to physical image quality descriptors (contrast and signal to noise ratio, SNR) and patient mean absorbed dose. Contrast agents of equal molar concentrations were used within a water slab (simulating the patient). The imaging conditions were chosen to represent adult and paediatric examinations. For all tube potentials studied (40-140 kV), the contrast agents with the highest atomic numbers (bismuth and thorium) gave the highest contrast. In analogue screen-film imaging, several other contrast agents could produce a higher image contrast than iodine in a limited range of tube potentials. This advantage could alternatively be effected as a reduced amount of administered contrast agent, or as a reduced mean absorbed dose in the patient. In digital imaging, a lower mean absorbed dose for a constant SNR than that with iodine can be achieved for ranges of tube potentials and contrast agents. Bismuth and thorium yield a lower dose than iodine at all studied tube potentials. Gadolinium and erbium could alternatively be used at a broad range of tube potentials above 90 kV with a dose penalty of only 5-20%.

  • 66.
    Sandborg, Michael
    et al.
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen. Linköpings universitet, Hälsouniversitetet.
    Dance, David
    The Royal Marsden Hospital.
    Alm Carlsson, Gudrun
    Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Persliden, Jan
    Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Monte Carlo study of grid performance in diagnostic radiology: task dependent opti­misation for screen-film imaging1994Ingår i: British Journal of Radiology, ISSN 0007-1285, E-ISSN 1748-880X, Vol. 67, s. 76-85Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    An optimization of anti-scatter grid design using Monte Carlo techniques in diagnostic radiology is presented. The criterion for optimization was to find the combinations of the grid parameters (lead strip width, grid ratio and strip density) and tube potential which result in the lowest mean absorbed dose in the patient at fixed image contrast. The optimization was performed in three irradiation geometries, representing different scattering conditions (paediatric examinations, and two adult lumbar spine examinations) and was restricted to grids using fibre materials in covers and interspaces. Grid designs currently available were studied, as were designs which use thinner strips (< 30 µm) and higher grid ratios (> 18). It was found that grids with widely different strip densities (strips cm–1) and grid ratios can have good performance provided that they are used with appropriate strip width and tube potential. With increasing amounts of scatter, the optimal grid requires thicker strips and higher grid ratios. Increasing the strip density and using thinner strips and higher grid ratios are generally required. Grids with low strip density (25 strips cm–1) were found to be less sensitive to alterations in strip width. Optimal grids for paediatric radiology require thinner strips (10–20 µm) than those in currently available grids. Grids on the market are best suited for examinations of the adult body in anteroposterior (AP) view. In the adult lateral view, representing the largest scattering volume, higher grid ratios (> 18) than those in existing grids would be optimal. Examples of good grid designs are given for each examination.

  • 67.
    Sandborg, Michael
    et al.
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen. Linköpings universitet, Hälsouniversitetet.
    Dance, David
    n/a.
    Alm Carlsson, Gudrun
    Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Persliden, Jan
    Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Results from an optimisation of grid design in diagnostic radiology1995Ingår i: Radiation Protection Dosimetry, ISSN 0144-8420, E-ISSN 1742-3406, Vol. 57, nr 1, s. 211-215Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Results of an optimisation of grid design using a Monte Carlo model of the imaging chain are presented. Patient dose is significantly reduced by changing from aluminium to fibre grid covers and interspaces while keeping contrast constant. Numerous commercial grids have been investigated to identify superior designs. For optimal use, grids with high strip density require thinner lead strips and higher ratios than grids with low strip density. In paediatric radiology, grids with very thin strips (10-20 µm), or an air gap can be considered. In an adult lumbar spine examination, the optimal grid ratios are higher (greater than 15) than in commercial grids. This is particularly accentuated for grids with high strip density, fibre interspaces and in the lateral view. For a given imaging task, it is possible to identify grids of different design that have good performance, provided an appropriate strip width and tube potential are selected.

  • 68.
    Sandborg, Michael
    et al.
    Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen. Linköpings universitet, Hälsouniversitetet.
    Dance, David
    n/a.
    Alm Carlsson, Gudrun
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Persliden, Jan
    Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet.
    Tapiovaara, Markku
    n/a.
    A Monte Carlo study of grid performance in diagnostic radiology: task-dependent opti­mization for digital imaging 1994Ingår i: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 39, nr 10, s. 1659-1676Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A Monte Carlo computational model has been used to optimize grid design in digital radiography. The optimization strategy involved finding grid designs that, for a constant signal-to-noise ratio, resulted in the lowest mean absorbed dose in the patient. Different examinations were simulated to explore the dependence of the optimal scatter-rejection technique on the imaging situation. A large range of grid designs was studied, including grids with both aluminium and fibre interspaces and covers, and compared to a 20 cm air gap. The results show that the optimal tube potential in each examination does not depend strongly on the scatter-rejection technique. There is a significant dose reduction associated with the use of fibre-interspaced grids, particularly in paediatric radiography. The optimal grid ratio and strip width increase with increasing scattering volume. With increasing strip density, the optimal strip width decreases, and the optimal grid ratio increases. Optimal grid ratios are higher than those used today, particularly for grids with large strip density. It is, however, possible to identify grids of good performance for a range of strip densities and grid ratios provided the strip width is selected accordingly. The computational method has been validated by comparison with measurements with a caesium iodide image receptor.

  • 69.
    Sandborg, Michael
    et al.
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Fransson, Sven Göran
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård. Östergötlands Läns Landsting, Hjärtcentrum, Kardiologiska kliniken.
    Pettersson, Håkan
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Evaluation of patient-absorbed doses during coronary angiography and intervention by femoral and radial artery access2004Ingår i: European Radiology, ISSN 0938-7994, E-ISSN 1432-1084, Vol. 14, nr 4, s. 653-658Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this study was to compare the radiation dose to patients during coronary angiography (CA) and coronary intervention (percutaneous transluminal coronary angioplasty, PTCA) by the femoral or radial artery access routes. A plane-parallel ionisation chamber, mounted on an under-couch X-ray tube (Siemens Coroskop TOP with an optional dose reduction system), recorded the dose-area product (DAP) to the patient from 40 coronary angiographies and 42 coronary interventions by the femoral route. The corresponding numbers for radial access were 36 and 24, respectively. Using a human-shaped phantom, conversion factors between maximum entrance surface dose and DAP were derived for CA and CA plus PTCA, respectively. The dose to the staff was measured with TL dosimeters for 22 examinations. Fluoroscopy time and DAP were significantly (p=0.003) larger using the radial access route for coronary angiography (7.5 min, 51 Gy cm2) than the corresponding values obtained from femoral access route (4.6 min, 38 Gy cm2. For CA plus PTCA the fluoroscopy time and DAP were larger for radial access (18.4 min, 75 Gy cm2) than for femoral access (12.5 min, 47 Gy cm2, p=0.013). In our experience, radial access did significantly prolong the fluoroscopy time and increase the patient doses.

  • 70.
    Sandborg, Michael
    et al.
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Langer, JE
    Computed tomography: physical principles and imaging techniques1999Ingår i: Gynecological Imaging, London: Elsevier Health Sciences , 1999, s. 31-46Kapitel i bok, del av antologi (Övrigt vetenskapligt)
  • 71.
    Sandborg, Michael
    et al.
    Linköpings universitet, Institutionen för medicin och hälsa, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Rossitti, Sandro
    Linköpings universitet, Institutionen för klinisk och experimentell medicin. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Sinnescentrum, Neurokirurgiska kliniken US.
    Pettersson, Håkan
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Local skin and eye lens equivalent odses in interventional neuroradiology2010Ingår i: European Radiology, ISSN 0938-7994, E-ISSN 1432-1084, Vol. 20, nr 3, s. 725-733Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose  To assess patient skin and eye lens doses in interventional neuroradiology and to assess both stochastic and deterministic radiation risks. Methods  Kerma–area product (P KA) was recorded and skin doses measured using thermoluminescence dosimeters. Estimated dose at interventional reference point (IRP) was compared with measured absorbed doses. Results  The average and maximum fluoroscopy times were 32 and 189 min for coiling and 40 and 144 min for embolisation. The average and maximum P KA for coiling were 121 and 436 Gy cm2, respectively, and 189 and 677 Gy cm2 for embolisation. The average and maximum values of the measured maximum absorbed skin doses were 0.72 and 3.0 Sv, respectively, for coiling and 0.79 and 2.1 Sv for embolisation. Two out of the 52 patients received skin doses in excess of 2 Sv. The average and maximum doses to the eye lens (left eye) were 51 and 515 mSv (coiling) and 71 and 289 mSv (embolisation). Conclusion  The ratio between the measured dose and the dose at the IRP was 0.44 ± 0.18 mSv/mGy indicating that the dose displayed by the x-ray unit overestimates the maximum skin dose but is still a valuable indication of the dose. The risk of inducing skin erythema and lens cataract during our hospital procedures is therefore small.

  • 72. Sastry, M
    et al.
    Gustafsson, Håkan
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik.
    Lund, Anders
    Linköpings universitet, Institutionen för fysik, kemi och biologi.
    Lund, Eva
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    51V(n,β)52Cr reaction for neutron dosimetry: Development and assessment of a spectrophotometric method for determination of Cr in vanadium at sub ppm level2004Ingår i: Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy, ISSN 1386-1425, E-ISSN 1873-3557, Vol. 60, nr 10, s. 2363-2367Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    With a view to monitoring the changes in coloration caused by the nuclear reaction 51V(n,β)52Cr in solution of vanadyl sulphate and using it for neutron dosimetry, electronic absorption spectra of vanadyl sulphate solutions were investigated at different concentrations of chromate impurity in micromolar range. It was observed that the presence of chromate enhances the absorptivity over a wide wavelength range serving essentially as a colouring agent for vanadium matrix, presumably due to charge transfer process. The absorbance at 380nm varied linearly over a wide concentration range. The limit of detection of chromate obtained is shown to be adequate for detecting neutron-induced chemical transmutation of vanadium to chromium under standard reactor conditions, when used with long path length cells. It was observed that the absorbance does not change on electron irradiation, suggesting that radiolytic effects due to beta decay, if any, do not interfere in the measurement of neutron-induced changes. In addition to its potential for neutron dosimetry, this is the first report of a simple and direct method of estimation of Cr in vanadium matrix at sub ppm level.

  • 73. Sparring Björkstén, Karin
    et al.
    Ekberg, Stefan
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Säfström, Pia
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiologi. Östergötlands Läns Landsting, Bildmedicinskt centrum, Avdelningen för radiologi US.
    Dige, N
    Granerus, Göran
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Klinisk fysiologi. Östergötlands Läns Landsting, Hjärtcentrum, Fysiologiska kliniken.
    A computerized human reference brain for rCBF/SPET technetium-99m exametazime (HMPAO) investigation of elderly2004Ingår i: Clinical Physiology and Functional Imaging, ISSN 1475-0961, E-ISSN 1475-097X, Vol. 24, nr 4, s. 196-204Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Using the bull's eye approach, a reference brain from the single photon emission tomography (SPET) images of 10 subjects aged 62-81 years with excellent mental and physical health was constructed. SPET images were acquired twice, 1 week apart, using a single detector rotating gamma camera collecting 64 planar images over a 360° orbit. The centre of each transaxial slice was first defined with an automatic edge detecting algorithm applied to an anterior-posterior and a side profile of the brain. Each slice was divided into 40 sectors. Maximum counts/pixel in each sector was picked. The 40 maximum count values from one transaxial slice were allowed to form a horizontal row in a new parametric image on the x-axis and slice number from the vertex to the basal parts of the brain on the y-axis. This new image was scaled to a 64 × 16 pixel matrix by interpolation, which meant a normalization of all studies to the same size. The parametric image in each subject was scaled with regard to intensity by a factor calculated by a normalization procedure using the least squares analysis. Mean and SD for each pixel were calculated, thereby constructing a 'mean parametric image', and a 'SD parametric image'. These two images are meant to be used as the reference brain for evaluation of patient studies. This method can be used for objective measurements of diffuse brain changes and for pattern recognition in larger groups of patients. Statistical multifactorial analysis of parameters used for acquisition and data processing is possible. © 2004 Blackwell Publishing Ltd.

  • 74. Tapiovaara, M
    et al.
    Sandborg, Michael
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    How should low-contrast detail detectability be measured in fluoroscopy?2004Ingår i: Medical physics (Lancaster), ISSN 0094-2405, Vol. 31, nr 9, s. 2564-2576Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The relationship and precision of four methods for measuring the low-contrast detail detectability in fluoroscopic imaging were studied. These included the physical measurement of the accumulation rate of the square of the signal-to-noise ratio (SNRrate2), two-alternative forced-choice (2-AFC) experiments, sixteen-alternative forced-choice (16-AFC) experiments and subjective determination of the threshold contrast. The precision and sensitivity of the threshold contrast measurement were seen to be modest in the constancy testing of fluoroscopic equipment: only large changes in system performance could be reliably detected by that method. The measurement of the SNRrate2 is suggested instead. The relationship between the results of the various methods were studied, and it was found that human performance can be related to SNRrate2 by introducing the concept of the effective image information integration time (teff). When measured for an unlimited observation time, it depicts the saturation of human performance in detecting a static low-contrast detail in dynamic image noise. Here, teff was found to be about 0.6 s in 2-AFC tests and 0.3 s in 16-AFC tests. © 2004 American Association of Physicists in Medicine.

  • 75.
    Tapiovaara, Markku
    et al.
    n/a.
    Servomaa, Antti
    n/a.
    Sandborg, Michael
    Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Linköpings universitet, Centrum för medicinsk bildvetenskap och visualisering, CMIV. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen. Linköpings universitet, Hälsouniversitetet.
    Dance, David
    n/a.
    Optimizing the imaging conditions in paediatric fluoroscopy2000Ingår i: Radiation Protection Dosimetry, ISSN 0144-8420, E-ISSN 1742-3406, Vol. 90, nr 1-2, s. 211-216Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Patient dose and image quality were studied in paediatric fluoroscopy. The study consisted of two parts: theoretical calculation of optimal imaging conditions by the Monte Carlo method and clinical measurements of dose rate and SNR2rate at six hospitals. For many imaging tasks the most efficient imaging technique in fluoroscopy is obtained by using high filtration, relatively low X ray tube potential and a fibre-interspaced and -covered grid for all but the smallest patients and X ray field sizes. The clinical measurements supported our theoretical results and revealed a notable variation in image quality and dose rate among the hospitals studied. Notable patient dose rate reduction seems possible in paediatric fluoroscopy by adjusting the equipment to work with more efficient imaging factors and a low image receptor input dose rate.

  • 76. Tingberg, A
    et al.
    Båth, M
    Håkansson, M
    Medin, J
    Besjakov, J
    Sandborg, Michael
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Alm-Carlsson, Gudrun
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Mattsson, S
    Månsson, LG
    Evaluation of image quality of lumbar spine images: A comparison between FFE and VGA2005Ingår i: Radiation Protection Dosimetry, ISSN 0144-8420, E-ISSN 1742-3406, Vol. 114, nr 1-3, s. 53-61Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: The aim of the present study is to compare two different methods for evaluation of the quality of clinical X-ray images. Methods: Based on fifteen lumbar spine radiographs, two new sets of images were created. A hybrid image set was created by adding two distributions of artificial lesions to each original image. The image quality parameters spatial resolution and noise were manipulated and a total of 210 hybrid images were created. A set of 105 disease-free images was created by applying the same combinations of spatial resolution and noise to the original images. The hybrid images were evaluated with the free-response forced error experiment (FFE) and the normal images with visual grading analysis (VGA) by nine experienced radiologists. Results: In the VGA study, images with low noise were preferred over images with higher noise levels. The alteration of the MTF had a limited influence on the VGA score. For the FFE study, the visibility of the lesions was independent of the sharpness and the noise level. No correlation was found between the two image quality measures. Conclusions: FFE is a precise method for evaluation of image quality, but the results are only valid for the type of lesion used in the study, whereas VGA is a more general method for clinical image quality assessment. The results of the FFE study indicate that there might be a potential to lower the dose levels in lumbar spine radiography without losing important diagnostic information. © The Author 2005. Published by Oxford University Press. All rights reserved.

  • 77. Tingberg, A
    et al.
    Båth, M
    Håkansson, M
    Medin, J
    Sandborg, Michael
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Alm-Carlsson, Gudrun
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Mattsson, S
    Gunnar Månsson, L
    Comparison of two methods for evaluation of image quality of lumbar spine radiographs2004Ingår i: SPIE Proc Jfr 2001 Preceedings of SPIE ISSN 1605-7422, ISSN 1017-2653, Vol. 5372Artikel i tidskrift (Refereegranskat)
  • 78. Tingberg, A
    et al.
    Eriksson, F
    Medin, J
    Besjakov, J
    Båth, M
    Håkansson, M
    Sandborg, Michael
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Almen, A
    Alm-Carlsson, Gudrun
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Mattsson, S
    Månsson, LG
    Inter-observer variation in masked and unmasked images for quality evaluation of clinical radiographs2005Ingår i: Radiation Protection Dosimetry, ISSN 0144-8420, E-ISSN 1742-3406, Vol. 114, nr 1-3, s. 62-68Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: To investigate the influence of masking on the inter-observer variation in image quality evaluation of clinical radiographs of chest and lumbar spine. Background: Inter-observer variation is a big problem in image quality evaluation since this variation is often much bigger than the variation in image quality between, for example, two radiographic systems. In this study, we have evaluated the effect of masking on the inter-observer variation. The idea of the masking was to force every observer to view exactly the same part of the image and to avoid the effect of the overall 'first impression' of the image. A discussion with a group of European expert radiologists before the study indicated that masking might be a good way to reduce the inter-observer variation. Methods: Five chest and five lumbar spine radiographs were collected together with detailed information regarding exposure conditions. The radiographs were digitised with a high-performance scanner and five different manipulations were performed, simulating five different exposure conditions. The contrast, noise and spatial resolution were manipulated by this method. The images were printed onto the film and the individual masks were produced for each film, showing only the parts of the images that were necessary for the image quality evaluation. The quality of the images was evaluated on ordinary viewing boxes by a large group of experienced radiologists. The images were examined with and without the masks with a set of image criteria (if fulfilled, 1 point, and not fulfilled, 0 point), and the mean score was calculated for each simulated exposure condition. Results: The results of this study indicate that - contrary to what was supposed - the inter-observer variation increased when the images were masked. In some cases, especially for chest, this increase was statistically significant. Conclusions: Based on the results of this study, image masking in studies of fulfilment of image criteria cannot be recommended. © The Author 2005. Published by Oxford University Press. All rights reserved.

  • 79. Tingberg, A
    et al.
    Herrmann, C
    Lanhede, B
    Almen, A
    Sandborg, Michael
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    McVey, G
    Mattsson, S
    Panzer, W
    Besjakov, J
    Månsson, LG
    Kheddache, S
    Alm-Carlsson, Gudrun
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Dance, DR
    Tylen, U
    Zankl, M
    Influence of the characteristic curve on the clinical image quality of lumbar spine and chest radiographs2004Ingår i: British Journal of Radiology, ISSN 0007-1285, E-ISSN 1748-880X, Vol. 77, nr 915, s. 204-215Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The "European Guidelines on Quality Criteria for Diagnostic Radiographic Images" do not address the choice of the film characteristic (H&D) curve, which is an important parameter for the description of a radiographic screen-film system. The image contrast of clinical lumbar spine and chest radiographs was altered by digital image processing techniques, simulating images with different H&D curves, both steeper and flatter than the original. The manipulated images were printed on film for evaluation. Seven experienced radiologists evaluated the clinical image quality by analysing the fulfilment of the European Image Criteria (ICS) and by visual grading analysis (VGA) of in total 224 lumbar spine and 360 chest images. A parallel study of the effect of the H&D curve has also been made using a theoretical model. The contrast (ΔOD) of relevant anatomical details was calculated, using a Monte Carlo simulation-model of the complete imaging system including a 3D voxel phantom of a patient. Correlations between the calculated contrast and the radiologists' assessment by VGA were sought. The results of the radiologists' assessment show that the quality in selected regions of lumbar spine and chest images can be significantly improved by the use of films with a steeper H&D curve compared with the standard latitude film. Significant (p<0.05) correlations were found between the VGA results and the calculations of the contrast of transverse processes and trabecular details in the lumbar spine vertebrae, and with the contrast of blood vessels in the retrocardiac area of the chest.

  • 80.
    Ullman, Gustaf
    et al.
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik.
    Sandborg, Michael
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    Dance, D
    Hunt, R
    Alm-Carlsson, Gudrun
    Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för medicin och vård, Medicinsk radiofysik. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.
    The influence of patient thickness and imaging system on patient dose and physical image quality in digital chest imaging2005Ingår i: Radiation Protection Dosimetry, ISSN 0144-8420, E-ISSN 1742-3406, Vol. 114, nr 1-3, s. 294-297Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this work was to study the influence of patient thickness, tube voltage and image detector on patient dose, contrast and ideal observer signal-to-noise ratio (SNRI), for pathological details positioned at different regions in the image in posterior-anterior (PA) chest radiology. A Monte Carlo computational model was used to compute measures of physical image quality (contrast, SNRI) and patient effective dose, E. Two metastasis-like details positioned in the central right lung and right lung near the spine, respectively, were studied. The tube voltage was varied between 100 and 150 kV and the patient thickness between 20 and 28 cm. Both, a computed radiography (CR) system and a direct radiography (DR) system, were investigated. The DR system provides both lower doses and better image quality compared with the CR system. The SNRI2/E is ∼2.9 times higher for the DR system compared with the CR system. © The Author 2005. Published by Oxford University Press. All rights reserved.

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