Interaction is critical for data analysis and sensemaking. However, designing interactive physicalizations is challenging as it requires cross-disciplinary knowledge in visualization, fabrication, and electronics. Interactive physicalizations are typically produced in an unstructured manner, resulting in unique solutions for a specific dataset, problem, or interaction that cannot be easily extended or adapted to new scenarios or future physicalizations. To mitigate these challenges, we introduce a computational design pipeline to 3D print network physicalizations with integrated sensing capabilities. Networks are ubiquitous, yet their complex geometry also requires significant engineering considerations to provide intuitive, effective interactions for exploration. Using our pipeline, designers can readily produce network physicalizations supporting selection-the most critical atomic operation for interaction-by touch through capacitive sensing and computational inference. Our computational design pipeline introduces a new design paradigm by concurrently considering the form and interactivity of a physicalization into one cohesive fabrication workflow. We evaluate our approach using (i) computational evaluations, (ii) three usage scenarios focusing on general visualization tasks, and (iii) expert interviews. The design paradigm introduced by our pipeline can lower barriers to physicalization research, creation, and adoption.

In structural biology, validation and verification of new atomic models are crucial and necessary steps which limit the production of reliable molecular models for publications and databases. An atomic model is the result of meticulous modeling and matching and is evaluated using a variety of metrics that provide clues to improve and refine the model so it fits our understanding of molecules and physical constraints. In cryo electron microscopy (cryo-EM) the validation is also part of an iterative modeling process in which there is a need to judge the quality of the model during the creation phase. A shortcoming is that the process and results of the validation are rarely communicated using visual metaphors.

This work presents a visual framework for molecular validation. The framework was developed in close collaboration with domain experts in a participatory design process. Its core is a novel visual representation based on 2D heatmaps that shows all available validation metrics in a linear fashion, presenting a global overview of the atomic model and provide domain experts with interactive analysis tools. Additional information stemming from the underlying data, such as a variety of local quality measures, is used to guide the user's attention toward regions of higher relevance. Linked with the heatmap is a three-dimensional molecular visualization providing the spatial context of the structures and chosen metrics. Additional views of statistical properties of the structure are included in the visual framework. We demonstrate the utility of the framework and its visual guidance with examples from cryo-EM.

Research in ML4VIS investigates how to use machine learning (ML) techniques to generate visualizations, and the field is rapidly growing with high societal impact. However, as with any computational pipeline that employs ML processes, ML4VIS approaches are susceptible to a range of ML-specific adversarial attacks. These attacks can manipulate visualization generations, causing analysts to be tricked and their judgments to be impaired. Due to a lack of synthesis from both visualization and ML perspectives, this security aspect is largely overlooked by the current ML4VIS literature. To bridge this gap, we investigate the potential vulnerabilities of ML-aided visualizations from adversarial attacks using a holistic lens of both visualization and ML perspectives. We first identify the attack surface (i.e., attack entry points) that is unique in ML-aided visualizations. We then exemplify five different adversarial attacks. These examples highlight the range of possible attacks when considering the attack surface and multiple different adversary capabilities. Our results show that adversaries can induce various attacks, such as creating arbitrary and deceptive visualizations, by systematically identifying input attributes that are influential in ML inferences. Based on our observations of the attack surface characteristics and the attack examples, we underline the importance of comprehensive studies of security issues and defense mechanisms as a call of urgency for the ML4VIS community.

Choosing whether to represent data in an abstract or concrete manner through sonification is generally dependent on the applicability of the dataset and personal preference of the designer. For supporting a visualization with a high level of abstraction, a sonification can purposefully act as a complement by giving concrete contextual cues to the data representation with the use of auditory icons. This paper presents a case study of using bird songs as auditory icons to give context to a biology visualization, and explores how additional information of the bird species can be conveyed together with the auditory icons with parameter mapping sonification. The auditory icons are used as a foundation to convey additional information of the dataset, either by creating a parametric auditory icon, or by adding an additional sonification that accompanies the auditory icon. A user evaluation was conducted to validate and compare the different sonification mappings. The results show that there is a subjective difference of how participants perceived the sonifications, where the participants preferred sonifications that had a concrete mapping design. The sonification approaches that are explored in this study have the potential to be applied to more general sonification designs.

An essential task of an air traffic controller is to manage the traffic flow by predicting future trajectories. Complex traffic patterns are difficult to predict and manage and impose cognitive load on the air traffic controllers. In this work we present an interactive visual analytics interface which facilitates detection and resolution of complex traffic patterns for air traffic controllers. The interface supports air traffic controllers in detecting complex clusters of aircraft and further enables them to visualize and simultaneously compare how different re-routing strategies for each individual aircraft yield reduction of complexity in the entire sector for the next hour. The development of the concepts was supported by the domain-specific feedback we received from six fully licensed and operational air traffic controllers in an iterative design process over a period of 14 months.

We present a neural network representation which can be used for visually analyzing the similarities and differences in a large corpus of trained neural networks. The focus is on architecture-invariant comparisons based on network weights, estimating similarities of the statistical footprints encoded by the training setups and stochastic optimization procedures. To make this possible, we propose a novel visual descriptor of neural network weights. The visual descriptor considers local weight statistics in a model-agnostic manner by encoding the distribution of weights over different model depths. We show how such a representation can extract descriptive information, is robust to different parameterizations of a model, and is applicable to different architecture specifications. The descriptor is used to create a model atlas by projecting a model library to a 2D representation, where clusters can be found based on similar weight properties. A cluster analysis strategy makes it possible to understand the weight properties of clusters and how these connect to the different datasets and hyper-parameters used to train the models.

One of the commonly used visualization techniques for multivariate data is the parallel coordinates plot. It provides users with a visual overview of multivariate data and the possibility to interactively explore it. While pattern recognition is a strength of the human visual system, it is also a strength of the auditory system. Inspired by the integration of the visual and auditory perception in everyday life, we introduce an audio-visual analytics design named Parallel Chords combining both visual and auditory displays. Parallel Chords lets users explore multivariate data using both visualization and sonification through the interaction with the axes of a parallel coordinates plot. To illustrate the potential of the design, we present (1) prototypical data patterns where the sonification helps with the identification of correlations, clusters, and outliers, (2) a usage scenario showing the sonification of data from non-adjacent axes, and (3) a controlled experiment on the sensitivity thresholds of participants when distinguishing the strength of correlations. During this controlled experiment, 35 participants used three different display types, the visualization, the sonification, and the combination of these, to identify the strongest out of three correlations. The results show that all three display types enabled the participants to identify the strongest correlation — with visualization resulting in the best sensitivity. The sonification resulted in sensitivities that were independent from the type of displayed correlation, and the combination resulted in increased enjoyability during usage.

Visual representations based on circular shapes are frequently used in visualization applications. One example are circos plots within bioinformatics, which bend graphs into a wheel of information with connective lines running through the center like spokes. The results are aesthetically appealing and impressive visualizations that fit long data sequences into a small quadratic space. However, the authors' experiences are that when asked, a visualization researcher would generally advise against making visualizations with radial layouts. Upon reviewing the literature we found that there is evidence that circular layouts are preferable in some cases, but we found no clear evidence for what layout is preferable for matrices and connective data in particular, which both are common data types in circos plots. In this work, we thus performed a user study to compare circular and linear layouts. The tasks are inspired by genomics data, but our results generalize to many other application areas, involving comparison and connective data. To build the prototype we utilized Gosling, a grammar for visualizing genomics data. We contribute empirical evidence on the suitedness of linear versus circular layouts, adding to the specific and general knowledge concerning perception of circular graphs. In addition, we contribute a case study evaluation of the grammar Gosling as a rapid prototyping language, confirming its utility and providing guidance on suitable areas for future development.

Multivariate networks are commonly found in realworld data-driven applications. Uncovering and understanding the relations of interest in multivariate networks is not a trivial task. This paper presents a visual analytics workflow for studying multivariate networks to extract associations between different structural and semantic characteristics of the networks (e.g., what are the combinations of attributes largely relating to the density of a social network?). The workflow consists of a neuralnetwork- based learning phase to classify the data based on the chosen input and output attributes, a dimensionality reduction and optimization phase to produce a simplified set of results for examination, and finally an interpreting phase conducted by the user through an interactive visualization interface. A key part of our design is a composite variable construction step that remodels nonlinear features obtained by neural networks into linear features that are intuitive to interpret. We demonstrate the capabilities of this workflow with multiple case studies on networks derived from social media usage and also evaluate the workflow with qualitative feedback from experts.

In industrial applications where the physical parameters are highly interconnected, keeping the process flow steady is a major concern for the operators. This is caused by the sensitivity of system to the process dynamics. As a result, a slight adjustment to a control parameter can significantly affect the efficiency of the system and thus impact the financial gain. Paper pulp production is an example of such a process, where operators continuously investigate the potential of changes in the process and predict the consequences of an adjustment before making a decision. Process parameter adjustments prescribed by simulated control models cannot be fully trusted as the external disturbances and the process inherent variabilities cannot be fully incorporated into the simulations. Therefore, to assess the viability of a strategy, operators often compare the situation with the historical records and trends during which the processes in the plant ran steadily. While previous research has mostly focused on developing advanced control models to simulate complex pulp production process, this work aims to support operators analytical reasoning by provision of effective data visualization. The contributions of our design study include a domain problem characterization and a linked-view visual encoding design, which aims to enhance operator's mental models independent of particular users or scenarios. Finally, by reflecting on the advantages of our choice of task abstraction technique, inherited from the ecological interface design framework [5], we reason for the generalizability of our approach to similar industrial applications.

An exoplanet is a planet outside of our solar system. Researchers study known exoplanets and gather data about them through observations and derived data. Ongoing efforts involve finding planets with an environment that supports life, which likely exists in what is known as the habitable zone around a star. Through a participatory design process, we developed a tool that enables the exploration of exoplanet attribute data and provides contextual visual information in a 3D spatial view that seamlessly presents

Dimensionality reduction (DR) plays a vital role in the visual analysis of high-dimensional data. One main aim of DR is to reveal hidden patterns that lie on intrinsic low-dimensional manifolds. However, DR often overlooks important patterns when the manifolds are distorted or masked by certain influential data attributes. This paper presents a feature learning framework, FEALM, designed to generate a set of optimized data projections for nonlinear DR in order to capture important patterns in the hidden manifolds. These projections produce maximally different nearest-neighbor graphs so that resultant DR outcomes are significantly different. To achieve such a capability, we design an optimization algorithm as well as introduce a new graph dissimilarity measure, named neighbor-shape dissimilarity. Additionally, we develop interactive visualizations to assist comparison of obtained DR results and interpretation of each DR result. We demonstrate FEALMs effectiveness through experiments and case studies using synthetic and real-world datasets.

We present Moliverse, an integration of the molecular visualization framework VIAMD into the astronomical visualization software OpenSpace, allowing us to bridge the two extreme ends of the scale spectrum to show, for example, the gas composition in a planets atmosphere or molecular structures in comet trails and can empower the creation of educational exhibitions. For that purpose we do not use a linear scale traversal but break the scale continuity and show molecular simulations as focus in the context of celestial bodies. We demonstrate the application of our concept in two storytelling scenarios and envision the application both for science presentations to lay audiences and for dedicated exploration, potentially also in a molecule-only environment.

Along with the increase of digitalization and automation, a new kind of working environment is emerging in the field of air traffic control. Instead of situating the control tower at the airport, it is now possible to remotely control the airport at any given location, i.e. in a remote tower center (RTC). However, by controlling the airport remotely, the situational awareness and sense of presence might be compromised. By using directional sound, a higher situational awareness could potentially be achieved while also offloading the visual perception which is heavily used in air traffic control. Suitable use cases for sonification in air traffic control were found through workshops with air traffic controllers. A sonification design named SonAir was developed based on the outcome of the workshops, and was integrated with an RTC simulator for evaluating to what degree SonAir could support air traffic controllers in their work. The results suggest that certain aspects of SonAir could be useful for air traffic controllers. A continuous sonification where the spatial positioning of aircraft were conveyed was experienced to be partially useful, but the intrusiveness of SonAir should be further considered to fit the air traffic controllers’ needs. An earcon that conveyed when an aircraft enters the airspace and from which direction was considered useful to support situational awareness.

In this perspective article we discuss a certain type of research on visualization for bioinformatics data, namely, methods targeting clinical use. We argue that in this subarea additional complex challenges come into play, particularly so in genomics. We here describe four such challenge areas, elicited from a domain characterization effort in clinical genomics. We also list opportunities for visualization research to address clinical challenges in genomics that were uncovered in the case study. The findings are shown to have parallels with experiences from the diagnostic imaging domain.

The typical workflow in molecular dynamics (MD) analysis requires several separate tools, often resulting in a lack of synergy and interaction between the individual analysis steps. This article presents VIAMD, an application designed to address this issue by integrating a 3D visualization of molecular trajectories with flexible analysis components. VIAMD uses an interactive scripting interface, allowing for property definition and evaluation. The application provides context-aware suggestions and expression feedback through information and visualizations. The user-defined properties can be explored and analyzed through the various components. This enables correlation with spatial conformations, statistical analysis of distributions, and powerful aggregation of multidimensional properties such as spatial distribution functions. VIAMD has the potential to advance research in many scientific disciplines and is a promising solution for improving the workflow of MD visualization and analysis.

Operators in air traffic control facing time- and safety-critical situations call for efficient, reliable and robust real-time processing and interpretation of complex data. Automation support tools aid controllers in these processes to prevent separation losses between aircraft. Issues of current support tools include limited what-if and what-else probe functionalities in relation to vertical solutions. This work presents the design and evaluation of two visual analytics interfaces that promote contextual awareness and support what-if and what-else probes in the spatio-temporal domain aiming to improve information integration and support controllers in prioritising conflict resolution. Both interfaces visualize vertical solution spaces against a time-altitude graph. The main contributions of this paper are: (a) the presentation of two interfaces for supporting conflict solving; (b) the novel representation of how vertical information and aircraft rate of climb and descent affect conflicts and (c) an evaluation and comparison of the interfaces with a traditional air traffic control support system. The evaluation study was performed with domain experts to compare the effects of visualization concepts on operator engagement in processing solutions suggested by the tools. Results show that the visualizations support operators ability to understand and resolve conflicts. Based on the results, general design guidelines for time-critical domains are proposed.

Engaging mass audiences with crucial societal issues, such as cli-mate change, can be provided through interactive exhibits designed around the paradigm of exploranation. We present example inter-active installations in the newly founded Wadstr¨oms Exploranation Laboratory that explain various aspects of climate change while allowing public participants to explore the real scientific data. We describe how effects and causes of climate change can be communi-cated by two of the installations that allow for interactive opportuni-ties to explore the underlying data while gaining insight into climate change sources and effects. We close with implications for future work on exploranation as an emerging visualization pedagogy in public spaces.

In molecular analysis, Spatial Distribution Functions (SDF) are fundamental instruments in answering questions related to spatial occurrences and relations of atomic structures over time. Given a molecular trajectory, SDFs can, for example, reveal the occurrence of water in relation to particular structures and hence provide clues of hydrophobic and hydrophilic regions. For the computation of meaningful distribution functions, the definition of molecular reference structures is essential. Therefore we introduce the concept of an internal frame of reference (IFR) for labeled point sets that represent selected molecular structures, and we propose an algorithm for tracking the IFR over time and space using a variant of Kabschs algorithm. This approach lets us generate a consistent space for the aggregation of the SDF for molecular trajectories and molecular ensembles. We demonstrate the usefulness of the technique by applying it to temporal molecular trajectories as well as ensemble datasets. The examples include different docking scenarios with DNA, insulin, and aspirin.

Common reporting styles for statistical results in scientific articles, such as p-values and confidence intervals (CI), have been reported to be prone to dichotomous interpretations, especially with respect to the null hypothesis significance testing framework. For example when the p-value is small enough or the CIs of the mean effects of a studied drug and a placebo are not overlapping, scientists tend to claim significant differences while often disregarding the magnitudes and absolute differences in the effect sizes. This type of reasoning has been shown to be potentially harmful to science. Techniques relying on the visual estimation of the strength of evidence have been recommended to reduce such dichotomous interpretations but their effectiveness has also been challenged. We ran two experiments on researchers with expertise in statistical analysis to compare several alternative representations of confidence intervals and used Bayesian multilevel models to estimate the effects of the representation styles on differences in researchers subjective confidence in the results. We also asked the respondents opinions and preferences in representation styles. Our results suggest that adding visual information to classic CI representation can decrease the tendency towards dichotomous interpretations - measured as the cliff effect: the sudden drop in confidence around p-value 0.05 - compared with classic CI visualization and textual representation of the CI with p-values. All data and analyses are publicly available at https://github.com/helske/statvis.

We present an atmospheric model tailored for the interactive visualization of planetary surfaces. As the exploration of the solar system is progressing with increasingly accurate missions and instruments, the faithful visualization of planetary environments is gaining increasing interest in space research, mission planning, and science communication and education. Atmospheric effects are crucial in data analysis and to provide contextual information for planetary data. Our model correctly accounts for the non-linear path of the light inside the atmosphere (in Earths case), the light absorption effects by molecules and dust particles, such as the ozone layer and the Martian dust, and a wavelength-dependent phase function for Mie scattering. The mode focuses on interactivity, versatility, and customization, and a comprehensive set of interactive controls make it possible to adapt its appearance dynamically. We demonstrate our results using Earth and Mars as examples. However, it can be readily adapted for the exploration of other atmospheres found on, for example, of exoplanets. For Earths atmosphere, we visually compare our results with pictures taken from the International Space Station and against the CIE clear sky model. The Martian atmosphere is reproduced based on available scientific data, feedback from domain experts, and is compared to images taken by the Curiosity rover. The work presented here has been implemented in the OpenSpace system, which enables interactive parameter setting and real-time feedback visualization targeting presentations in a wide range of environments, from immersive dome theaters to virtual reality headsets.

While the usefulness of 3D visualizations has been shown for a range of clinical applications such as treatment planning it still had difficulties in being adopted in widespread clinical practice. This chapter describes how multi-touch surfaces with patient-specific data have contributed to breaking this barrier, paving the way for adoption into clinical practice and, at the same time, also found widespread use in educational settings and in communication of science to the general public. The key element identified for this adoption is the string of steps found in the full imaging chain, which will be described as an introduction to the topic in this chapter. Emphasis in the chapter is, however, visualization aspects, e.g., intuitive interaction with patient-specific data captured with the latest high speed and high-quality imaging modalities. A necessary starting point for this discussion is the foundations of and state-of-the-art in volumetric rendering, which form the basis for the underlying theory part of the chapter. The chapter presents two use cases. One case is focusing on the use of multi-touch in medical education and the other is focusing on the use of touch surfaces at public venues, such as science centers and museums. 

Recent technical developments and early clinical examples support that precision medicine has potential to provide novel diagnostic and therapeutic solutions for patients with complex diseases, who are not responding to existing therapies. Those solutions will require integration of genomic data with routine clinical, imaging, sensor, biobank and registry data. Moreover, user-friendly tools for informed decision support for both patients and clinicians will be needed. While this will entail huge technical, ethical, societal and regulatory challenges, it may contribute to transforming and improving health care towards becoming predictive, preventive, personalised and participatory (4P-medicine).

We survey the state of the art of spatial interfaces for 3D visualization. Interaction techniques are crucial to data visualization processes and the visualization research community has been calling for more research on interaction for years. Yet, research papers focusing on interaction techniques, in particular for 3D visualization purposes, are not always published in visualization venues, sometimes making it challenging to synthesize the latest interaction and visualization results. We therefore introduce a taxonomy of interaction technique for 3D visualization. The taxonomy is organized along two axes: the primary source of input on the one hand and the visualization task they support on the other hand. Surveying the state of the art allows us to highlight specific challenges and missed opportunities for research in 3D visualization. In particular, we call for additional research in: (1) controlling 3D visualization widgets to help scientists better understand their data, (2) 3D interaction techniques for dissemination, which are under-explored yet show great promise for helping museum and science centers in their mission to share recent knowledge, and (3) developing new measures that move beyond traditional time and errors metrics for evaluating visualizations that include spatial interaction.

We present a state-of-the-art report on visualization in astrophysics. We survey representative papers from both astrophysics and visualization and provide a taxonomy of existing approaches based on data analysis tasks. The approaches are classified based on five categories: data wrangling, data exploration, feature identification, object reconstruction, as well as education and outreach. Our unique contribution is to combine the diverse viewpoints from both astronomers and visualization experts to identify challenges and opportunities for visualization in astrophysics. The main goal is to provide a reference point to bring modern data analysis and visualization techniques to the rich datasets in astrophysics.

This paper presents an empirical study on the weights of neural networks, where we interpret each model as a point in a high-dimensional space – the neural weight space. To explore the complex structure of this space, we sample from a diverse selection of training variations (dataset, optimization procedure, architecture,etc.) of neural network classifiers, and train a large number of models to represent the weight space. Then, we use a machine learning approach for analyzing and extracting information from this space. Most centrally, we train a number of novel deep meta-classifiers withthe objective of classifying different properties of the training setup by identifying their footprints in the weight space. Thus, the meta-classifiers probe for patterns induced by hyper-parameters, so that we can quantify how much, where, and when these are encoded through the optimization process. This provides a novel and complementary view for explainable AI, and we show how meta-classifiers can reveal a great deal of information about the training setup and optimization, by only considering a small subset of randomly selected consecutive weights. To promote further research on the weight space, we release the neural weight space (NWS) dataset – a collection of 320K weightsnapshots from 16K individually trained deep neural networks.

We study with a two-dimensional particle-in-cell simulation the stability of a discontinuity or piston, which separates an electron–positron cloud from a cooler electron–proton plasma. Such a piston might be present in the relativistic jets of accreting black holes separating the jet material from the surrounding ambient plasma and when pair clouds form during an x-ray flare and expand into the plasma of the accretion disk corona. We inject a pair plasma at a simulation boundary with a mildly relativistic temperature and mean speed. It flows across a spatially uniform electron–proton plasma, which is permeated by a background magnetic field. The magnetic field is aligned with one simulation direction and oriented orthogonally to the mean velocity vector of the pair cloud. The expanding pair cloud expels the magnetic field and piles it up at its front. It is amplified to a value large enough to trap ambient electrons. The current of the trapped electrons, which is carried with the expanding cloud front, drives an electric field that accelerates protons. A solitary wave grows and changes into a piston after it saturated. Our simulations show that this piston undergoes a collisionless instability similar to a Rayleigh–Taylor instability. The undular mode grows and we observe fingers in the proton density distribution. The effect of the instability is to deform the piston but it cannot destroy it.

Air traffic control is a safety critical high-risk environment where operators need to analyse and interpret traffic dynamics of spatio-temporal data in real-time. To support the air traffic controller in safely separating traffic, earlier research has applied real-time visualisation techniques that explore the constraints and solution spaces of separation problems. Traditionally, situation displays for conflict detection and resolution have used visualisations that convey information about the relative horizontal position between aircraft. Although vertical solutions for solving conflicts are common, and often a preferred among controllers, visualisations typically provide limited information about the vertical relationship between aircraft. This paper presents a design study of an interactive conflict detection and resolution support tool and explores techniques for real-time visualisation of spatio-temporal data. The design evolution has incorporated several activities, including an initial work domain analysis, iterative rounds of programming, design, and evaluations with a domain expert, and an evaluation with eight active controllers. The heading-time-altitude visualisation system is developed based on formulating and solving aircraft movements in a relative coordinate system. A polar-graph visualisation technique is used to construct a view of conflicting aircraft vertical solution spaces in the temporal domain. Using composite glyphs, the final heading-time-altitude visualisation provides a graphical representation of both horizontal and vertical solution spaces for the traffic situation.

Frequency distributions (FD) are an important instrument when analyzing and investigating scientific data. In volumetric visualization, for example, frequency distributions visualized as histograms, often assist the user in the process of designing transferfunction (TF) primitives. Yet a single point in the distribution can correspond to multiple features in the data, particularly inlow-dimensional TFs that dominate time-critical domains such as health care. In this paper, we propose contributions to thearea of medical volume data exploration, in particular Computed Tomography (CT) data, based on the decomposition of localfrequency distributions (LFD). By considering the local neighborhood utilizing LFDs we can incorporate a measure for neighborhood similarity to differentiate features thereby enhancing the classification abilities of existing methods. This also allowsus to link the attribute space of the histogram with the spatial properties of the data to improve the user experience and simplifythe exploration step. We propose three approaches for data exploration which we illustrate with several visualization caseshighlighting distinct features that are not identifiable when considering only the global frequency distribution. We demonstratethe power of the method on selected datasets

The complexity of todays visualization applications demands specific visualization systems tailored for the development of these applications. Frequently, such systems utilize levels of abstraction to improve the application development process, for insta

Human knowledge about the cosmos is rapidly increasing as instruments and simulations are generating new data supporting the formation of theory and understanding of the vastness and complexity of the universe. OpenSpace is a software system that takes on the mission of providing an integrated view of all these sources of data and supports interactive exploration of the known universe from the millimeter scale showing instruments on spacecrafts to billions of light years when visualizing the early universe. The ambition is to support research in astronomy and space exploration, science communication at museums and in planetariums as well as bringing exploratory astrographics to the class room. There is a multitude of challenges that need to be met in reaching this goal such as the data variety, multiple spatio-temporal scales, collaboration capabilities, etc. Furthermore, the system has to be flexible and modular to enable rapid prototyping and inclusion of new research results or space mission data and thereby shorten the time from discovery to dissemination. To support the different use cases the system has to be hardware agnostic and support a range of platforms and interaction paradigms. In this paper we describe how OpenSpace meets these challenges in an open source effort that is paving the path for the next generation of interactive astrographics.

While volume rendering for scalar fields has been advanced into a powerful visualisation method, similar volumetric representations for tensor fields are still rare. The complexity of the data challenges not only the rendering but also the design of the transfer function. In this paper we propose an interface using glyph widgets to design a transfer function for the rendering of tensor data sets. Thereby the transfer function (TF) controls a volume rendering which represents sought after tensor-features and a texture that conveys directional information. The basis of the design interface is a two-dimensional projection of the attribute space. Characteristic representatives in the form of glyphs support an intuitive navigation through the attribute space. We provide three different options to select the representatives: automatic selection based on attribute space clustering, uniform sampling of the attribute space, or manually selected representatives. In contrast to glyphs placed into the 3D volume, we use glyphs with complex geometry as widgets to control the shape and extent of the representatives. In the final rendering the glyphs with their assigned colors play a similar role as a legend in an atlas like representation. The method provides an overview of the tensor field in the 3D volume at the same time as it allows the user to explore the tensor field in an attribute space. We demonstrate the flexibility of our approach on tensor fields for selected data sets with very different characteristics.

We present an analysis of the impact of hyper-parameters for an ensemble of neural networks using tailored visualization techniques to understand the complicated relationship between hyper-parameters and model performance. The high-dimensional error surface spanned by the wide range of hyper-parameters used to specify and optimize neural networks is difficult to characterize - it is non-convex and discontinuous, and there could be complex local dependencies between hyper-parameters. To explore these dependencies, we make use of a large number of sampled relations between hyper-parameters and end performance, retrieved from thousands of individually trained convolutional neural network classifiers. We use a structured selection of visualization techniques to analyze the impact of different combinations of hyper-parameters. The results reveal how complicated dependencies between hyper-parameters influence the end performance, demonstrating how the complete picture painted by considering a large number of trainings simultaneously can aid in understanding the impact of hyper-parameter combinations.

The articles in this special section focus on scientific visualization and information technology. Visual communication can provide a method to make information known or understandable to the general public. Visual communication in public spaces, such as museums, science centers, and mainstream media, is gaining momentum driven by the success of interactive visualization in exploration of scientific data. We are now seeing different installations and specific tools to convey knowledge through interactive and exploratory visual communication in a wide variety of settings. For this Special Issue, we solicited papers describing work based on visualization in public spaces from both a technology and methodology perspective.

We present an application, and its development process, for interactive visual analysis of brain imaging data and clinical measurements. The application targets neuroscientists interested in understanding the correlations between active brain regions and physiological or psychological factors. The application has been developed in a participatory design process and has subsequently been released as the free software VisualNeuro. From initial observations of the neuroscientists workflow, we concluded that while existing tools provide powerful analysis options, they lack effective interactive exploration requiring the use of many tools side by side. Consequently, our application has been designed to simplify the workflow combining statistical analysis with interactive visual exploration. The resulting environment comprises parallel coordinates for effective overview and selection, Welchs t-test to filter out brain regions with statistically significant differences and multiple visualizations for comparison between brain regions and clinical parameters. These exploration concepts enable neuroscientists to interactively explore the complex bidirectional interplay between clinical and brain measurements and easily compare different patient groups. A qualitative user study has been performed with three neuroscientists from different domains. The study shows that the developed environment supports simultaneous analysis of more parameters, provides rapid pathways to insights and is an effective tool for hypothesis formation.

We present an interactive visual environment for linked analysis of brain imaging and clinical measurements. The environment is developed in an iterative participatory design process involving neuroscientists investigating the causes of brain-related complex diseases. The hypotheses formation process about correlations between active brain regions and physiological or psychological factors in studies with hundreds of subjects is a central part of the investigation. Observing the reasoning patterns during hypotheses formation, we concluded that while existing tools provide powerful analysis options, they lack effective interactive exploration, thus limiting the scientific scope and preventing extraction of knowledge from available data.Based on these observations, we designed methods that support neuroscientists by integrating their existing statistical analysis of multivariate subject data with interactive visual explorationto enable them to better understand differences between patient groups and the complex bidirectional interplay between clinical measurement and the brain. These exploration concepts enable neuroscientists, for the first time during their investigations, to interactively move between and reason about questions such as ‘which clinical measurements are correlated with a specific brain region?’ or ‘are there differences in brain activity between depressed young and old subjects?’. The environment uses parallel coordinates for effective overview and selection of subject groups, Welch's t-test to filter out brain regions with statistically significant differences, and multiple visualizations of Pearson correlations between brain regions and clinical parameters to facilitate correlation analysis. A qualitative user study was performed with three neuroscientists from different domains. The study shows that the developed environment supports simultaneous analysis of more parameters, provides rapid pathways to insights, and is an effective support tool for hypothesis formation.

We present a visualization application that enables effective interactive visual analysis of large-scale 3D histopathology, that is, high-resolution 3D microscopy data of human tissue. Clinical work flows and research based on pathology have, until now, largely been dominated by 2D imaging. As we will show in the paper, studying volumetric histology data will open up novel and useful opportunities for both research and clinical practice. Our starting point is the current lack of appropriate visualization tools in histopathology, which has been a limiting factor in the uptake of digital pathology. Visualization of 3D histology data does pose difficult challenges in several aspects. The full-color datasets are dense and large in scale, on the order of 100,000 x 100,000 x 100 voxels. This entails serious demands on both rendering performance and user experience design. Despite this, our developed application supports interactive study of 3D histology datasets at native resolution. Our application is based on tailoring and tuning of existing methods, system integration work, as well as a careful study of domain specific demands emanating from a close participatory design process with domain experts as team members. Results from a user evaluation employing the tool demonstrate a strong agreement among the 14 participating pathologists that 3D histopathology will be a valuable and enabling tool for their work.

Selecting components and observing changes ofproperties and configurations over time is an important step in the analysis of molecular dynamics (MD) data. In this paper, we present a selection tool combining text-based queries with spatial selection and filtering. Morphological operations facilitate refinement of the selection by growth operators, e.g. across covalent bonds. The combination of different selection paradigms enables flexible and intuitive analysis on different levels of detail and visual depiction of molecular events. Immediate visual feedback during interactions ensures a smooth exploration of the data. We demonstrate the utility of our selection framework by analyzing temporal changes in the secondary structure of poly-alanineand the binding ofaspirin to phospholipase A2.

Aims. We study the effect a guiding magnetic field has on the formation and structure of a pair jet that propagates through a collisionless electron–proton plasma at rest.

Methods. We model with a particle-in-cell (PIC) simulation a pair cloud with a temperature of 400 keV and a mean speed of 0.9c (c - light speed). Pair particles are continuously injected at the boundary. The cloud propagates through a spatially uniform, magnetized, and cool ambient electron–proton plasma at rest. The mean velocity vector of the pair cloud is aligned with the uniform background magnetic field. The pair cloud has a lateral extent of a few ion skin depths.

Results. A jet forms in time. Its outer cocoon consists of jet-accelerated ambient plasma and is separated from the inner cocoon by an electromagnetic piston with a thickness that is comparable to the local thermal gyroradius of jet particles. The inner cocoon consists of pair plasma, which lost its directed flow energy while it swept out the background magnetic field and compressed it into the electromagnetic piston. A beam of electrons and positrons moves along the jet spine at its initial speed. Its electrons are slowed down and some positrons are accelerated as they cross the head of the jet. The latter escape upstream along the magnetic field, which yields an excess of megaelectronvolt positrons ahead of the jet. A filamentation instability between positrons and protons accelerates some of the protons, which were located behind the electromagnetic piston at the time it formed, to megaelectronvolt energies.

Conclusions. A microscopic pair jet in collisionless plasma has a structure that is similar to that predicted by a hydrodynamic model of relativistic astrophysical pair jets. It is a source of megaelectronvolt positrons. An electromagnetic piston acts as the contact discontinuity between the inner and outer cocoons. It would form on subsecond timescales in a plasma with a density that is comparable to that of the interstellar medium in the rest frame of the latter. A supercritical fast magnetosonic shock will form between the pristine ambient plasma and the jet-accelerated plasma on a timescale that exceeds our simulation time by an order of magnitude.

We present the results from a particle-in-cell (PIC) simulation that models the interaction between a spatially localized electron-positron cloud and an electron-ion plasma. The latter is permeated by a magnetic field that is initially spatially uniform and aligned with the mean velocity vector of the pair cloud. The pair cloud expels the magnetic field and piles it up into an electromagnetic piston. Its electromagnetic field is strong enough to separate the pair cloud from the ambient plasma in the direction that is perpendicular to the cloud propagation direction. The piston propagates away from the spine of the injected pair cloud and it accelerates the protons to a high nonrelativistic speed. The accelerated protons form an outer cocoon that will eventually become separated from the unperturbed ambient plasma by a fast magnetosonic shock. No electromagnetic piston forms at the front of the cloud and a shock is mediated here by the filamentation instability. The final plasma distribution resembles that of a hydrodynamic jet. Collisionless plasma jets may form in the coronal plasma of accreting black holes and the interaction between the strong magnetic field of the piston and the hot pair cloud may contribute to radio emissions by such objects.

A very stable binding site for the interaction between a pentameric oligothiophene and an amyloid-(1-42) fibril has been identified by means of non-biased molecular dynamics simulations. In this site, the probe is locked in an all-trans conformation with a Coulombic binding energy of 1200 kJ mol(-1) due to the interactions between the anionic carboxyl groups of the probe and the cationic epsilon-amino groups in the lysine side chain. Upon binding, the conformationally restricted probes show a pronounced increase in molecular planarity. This is in line with the observed changes in luminescence properties that serve as the foundation for their use as biomarkers.

Science communication is facing a paradigm shift, based on the convergence of exploratory and explanatory visualization. In this article, we coin the term exploranation to denote the way in which visualization methods from scientific exploration can be used to communicate results and how methods in explanatory visualization can enrich exploration.

Results of planetary mapping are often shared openly for use in scientific research and mission planning. In its raw format, however, the data is not accessible to non-experts due to the difficulty in grasping the context and the intricate acquisition process. We present work on tailoring and integration of multiple data processing and visualization methods to interactively contextualize geospatial surface data of celestial bodies for use in science communication. As our approach handles dynamic data sources, streamed from online repositories, we are significantly shortening the time between discovery and dissemination of data and results. We describe the image acquisition pipeline, the pre-processing steps to derive a 2.5D terrain, and a chunked level-of-detail, out-of-core rendering approach to enable interactive exploration of global maps and high-resolution digital terrain models. The results are demonstrated for three different celestial bodies. The first case addresses high-resolution map data on the surface of Mars. A second case is showing dynamic processes. such as concurrent weather conditions on Earth that require temporal datasets. As a final example we use data from the New Horizons spacecraft which acquired images during a single flyby of Pluto. We visualize the acquisition process as well as the resulting surface data. Our work has been implemented in the OpenSpace software [8], which enables interactive presentations in a range of environments such as immersive dome theaters. interactive touch tables. and virtual reality headsets.

This viewpoint presents OpenSpace, an open-source astrovisualization software project designed to bridge the gap between scientific discoveries and their public dissemination. A wealth of data exists for space missions from NASA and other sources. OpenSpace brings together this data and combines it in a range of immersive settings. Through non-linear storytelling and guided exploration, interactive immersive experiences help the public to engage with advanced space mission data and models, and thus be better informed and educated about NASA missions, the solar system and outer space. We demonstrate this capability by exploring the OSIRIS-Rex mission.

This article presents the development of open-source software called OpenSpace that bridges the gap between scientific discoveries and public dissemination and thus paves the way for the next generation of science communication and data exploration. The article describes how the platform enables interactive presentations of dynamic and time-varying processes by domain experts to the general public. The concepts are demonstrated through four cases: Image acquisitions of the New Horizons and Rosetta spacecraft, the dissemination of space weather phenomena, and the display of high-resolution planetary images. Each case has been presented at public events with great success. These cases highlight the details of data acquisition, rather than presenting the final results, showing the audience the value of supporting the efforts of the scientific discovery.

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We present a visual exploration environment tailored for large-scale spatio-temporal molecular dynamics simulation data. The environment is referred to as VIA-MD (visual interactive analysis of molecular dynamics) and has been developed in a participatory design process with domain experts on molecular dynamics simulations of complex molecular systems. A key feature of our approach is the support for linked interactive 3D exploration of geometry and statistical analysis using dynamic temporal windowing and animation. Based on semantic level descriptions and hierarchical aggregation of molecular properties we enable interactive filtering, which enables the user to effectively find spatial, temporal and statistical patterns. The VIA-MD environment provides an unprecedented tool for analysis of complex microscopic interactions hidden in large data volumes. We demonstrate the utility of the VIA-MD environment with four use cases. The first two deal with simulation of amyloid plaque associated with development of Alzheimer's, and we study an aqueous solution of 100 probes and an amyloid fibril. The identification of interaction "hotspots" is achieved with the use of combined filter parameters connected with probe molecular planarity and probe-fibril interaction energetics. The third and fourth examples show the wide applicability of the environment by applying it to analysis of molecular properties in material design.

Application-oriented papers provide an important way to invigorate and cross-pollinate the visualization field, but the exact criteria for judging an application paper's merit remain an open question. This article builds on a panel at the 2016 IEEE Visualization Conference entitled "Application Papers: What Are They, and How Should They Be Evaluated?" that sought to gain a better understanding of prevalent views in the visualization community. This article surveys current trends that favor application papers, reviews the benefits and contributions of this paper type, and discusses their assessment in the review process. It concludes with recommendations to ensure that the visualization community is more inclusive to application papers.

We present a method for interactive global illumination of both static and time-varying volumetric data based on reduction of the overhead associated with re-computation of photon maps. Our method uses the identification of photon traces invariant to changes of visual parameters such as the transfer function (TF), or data changes between time-steps in a 4D volume. This lets us operate on a variant subset of the entire photon distribution. The amount of computation required in the two stages of the photon mapping process, namely tracing and gathering, can thus be reduced to the subset that are affected by a data or visual parameter change. We rely on two different types of information from the original data to identify the regions that have changed. A low resolution uniform grid containing the minimum and maximum data values of the original data is derived for each time step. Similarly, for two consecutive time-steps, a low resolution grid containing the difference between the overlapping data is used. We show that this compact metadata can be combined with the transfer function to identify the regions that have changed. Each photon traverses the low-resolution grid to identify if it can be directly transferred to the next photon distribution state or if it needs to be recomputed. An efficient representation of the photon distribution is presented leading to an order of magnitude improved performance of the raycasting step. The utility of the method is demonstrated in several examples that show visual fidelity, as well as performance. The examples show that visual quality can be retained when the fraction of retraced photons is as low as 40%-50%.