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  • 1.
    Turner, Anthony
    Linköping University, Department of Physics, Chemistry and Biology, Biosensors and Bioelectronics.
    24th Anniversary World Congress on Biosensors – Biosensors 20142014Conference proceedings (editor) (Refereed)
    Abstract [en]

    Welcome to Biosensors 2014 and welcome to Melbourne, ranked as the world's most liveable city!

    This is the 24th anniversary edition of the World Congress on Biosensors and we continue to evolve, adapt and grow into new roles to serve the analytical needs of a rapidly changing society. Advances in telecommunications, expert systems and distributed diagnostics are prompting us to question the conventional ways we deliver healthcare, while robust industrial sensors are facilitating new paradigms in R&D and production. Personalisation of everything from medicine to environmental control, is giving new impetus to consumer choice and ownership of information, and will inevitably generate new payment structures and business models. Moreover, a deeper understanding of the bio/electronic interface leads us towards new horizons in areas such as bionics, power generation and computing.  Wearable, mobile and integrated sensors are becoming common place, but most current products have taken the easy path of incorporating physical sensors for parameters such as temperature, pressure, orientation or position. There is still a glaring absence of suitably robust and convenient commercial biosensors for body chemistries and ecosystems, and therein lies the real opportunities for progress.  We are a still-emerging technology that is fuelling scientific discovery and underpinning new products to enhance the length and quality of life.

    Always in a new country and always with fresh plenary speakers, we aim to reflect the latest and the best in Biosensors. This three-day event, organised by Elsevier in association with Biosensors & Bioelectronics, consists of two daily plenary presentations from leading figures in the field, followed by four parallel sessions, comprising a rigorously refereed selection of submitted papers. This year, we received 1,156 submissions of which 124 with be presented as regular Oral papers, with an additional 20 singled out as Invited talks and a further 12 selected for extended Keynote talks. The Keynote speakers have also been invited to submit full papers for consideration for the Biosensors and Bioelectronics Prize for the most original contribution to the Congress and the winners will be announced at the conference banquet on Thursday night. There will also be poster awards and you will find voting slips for each of the three days in your delegate bags. The winners of these awards and a prize draw, sponsored by Linköping University and Acreo Swedish ICT, will be announced at the closing ceremony on Friday. In order to enhance the valued medium of poster presentation, this year we have introduced a new Poster in my Pocket Ap.  Poster presenters have been able to upload a PDF of their poster prior to the conference to help increase the exposure of their work. This compliments the other new Ap introduced this year to place the full programme at your fingertips. Selected oral presentations will also have the opportunity to upload their talks online for future viewing.

    The academic programme, as usual, is enhanced by a fine collection of commercial exhibits and in addition to browsing their stands; you will be able to hear short elevator pitches during the breaks. We must thank our main commercial sponsor, Ercon for their generous and continued support of our congress. Thanks also to New Tools for Health for sponsoring the pre-congress Networking Event.  Now a regular feature for Biosensors, we have a pre-congress school, this year on Optical Biosensors, which is brought to you by Profs Fran Ligler and Tanya Monro. Last, but not least I must thank our marvellous Local Organising Committee chaired by Prof Justin Gooding, our hard working main Organising Committee, all the speakers and delegates, and the Elsevier team for all their support.

    Our delegates come from the four corners of the globe to hear the science, to grasp the opportunities and to meet the people; it’s going to be the best meeting yet. Enjoy and don’t forget to join us again in Gothenburg, Sweden, 24-27 May for Biosensor 2016!

  • 2.
    Hallert, Eva
    et al.
    Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Rehabilitation Center. Linköping University, Department of Medical and Health Sciences, Health Technology Assessment and Health Economics.
    Husberg, Magnus
    Linköping University, Department of Medical and Health Sciences, Health Technology Assessment and Health Economics. Linköping University, Faculty of Health Sciences.
    Skogh, Thomas
    Linköping University, Department of Clinical and Experimental Medicine, Rheumatology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Rheumatology.
    28-joint count disease activity score at 3 months after diagnosis of early rheumatoid arthritis is strongly associated with direct and indirect costs over the following 4 years: the Swedish TIRA project2011In: Rheumatology, ISSN 1462-0324, E-ISSN 1462-0332, Vol. 50, no 7, 1259-1267 p.Article in journal (Refereed)
    Abstract [en]

    Methods. Three-hundred and twenty patients with early (1 year) RA were assessed at regular intervals. Clinical and laboratory data were collected and patients reported health-care utilization and number of days lost from work. At 3-month follow-up, patients were divided into two groups according to disease activity, using DAS-28 with a cut-off level at 3.2. Direct and indirect costs and EuroQol-5D over the following 4 years were compared between the groups. Multivariate regression models were used to control for possible covariates. Results. Three months after diagnosis, a DAS-28 level of epsilon 3.2 was associated with high direct and indirect costs over the following 4 years. Patients with DAS-28 epsilon 3.2 at 3-month follow-up had more visits to physician, physiotherapist, occupational therapist and nurse, higher drug costs, more days in hospital and more extensive surgery compared with patients with 3-month DAS-28 less than 3.2. Number of days lost from work due to sick leave and permanent work disability was also higher in this group. The effect of disease activity on health-related quality of life was highly significant. In regression models, DAS-28 at 3-month follow-up was significantly associated with costs over the following years. Conclusions. Three months after diagnosis, DAS-28 is an important prognostic marker regarding health-care utilization and costs. Achieving remission or low disease activity 3 months after diagnosis is likely to decrease morbidity, increase quality of life and save costs for the patient and for society over the following years.

  • 3.
    Grönwall, Christina
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Gustafsson, Fredrik
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    3D Content-Based Model Matching using Geometric Features2006Report (Other academic)
    Abstract [en]

    We present an approach that utilizes efficient geometric feature extraction and a matching method that takes articulation into account. It is primarily applicable for man-made objects. First the object is analyzed to extract geometric features, dimensions and rotation are estimated and typical parts, so-called functional parts, are identified. Examples of functional parts are a box's lid, a building's chimney, or a battle tank's barrel. We assume a model library with full annotation. The geometric features are matched with the model descriptors, to gain fast and early rejection of non-relevant models. After this pruning the objectis matched with relevant, usually few, library models. We propose a sequential matching, where the number of functional parts increases in each iteration. The division into parts increases the possibility for correct matching result when several similar models are available. The approach is exemplifi…ed with an vehicle recognition application, where some vehicles have functional parts.

  • 4.
    Dahlin, Johan
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    3D Modeling of Indoor Environments2013Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    With the aid of modern sensors it is possible to create models of buildings. These sensorstypically generate 3D point clouds and in order to increase interpretability and usability,these point clouds are often translated into 3D models.In this thesis a way of translating a 3D point cloud into a 3D model is presented. The basicfunctionality is implemented using Matlab. The geometric model consists of floors, wallsand ceilings. In addition, doors and windows are automatically identified and integrated intothe model. The resulting model also has an explicit representation of the topology betweenentities of the model. The topology is represented as a graph, and to do this GraphML isused. The graph is opened in a graph editing program called yEd.The result is a 3D model that can be plotted in Matlab and a graph describing the connectivitybetween entities. The GraphML file is automatically generated in Matlab. An interfacebetween Matlab and yEd allows the user to choose which rooms should be plotted.

  • 5.
    Grönwall, Christina
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, Faculty of Science & Engineering.
    Tolt, Gustav
    FOI.
    Larsson, Håkan
    FOI.
    Lif, Patrik
    FOI.
    Bissmarck, Fredrik
    FOI.
    Tulldahl, Michael
    FOI.
    Wikberg, Per
    FOI.
    Thorstensson, Mirko
    FOI.
    3D sensing and imaging for UAVs: Invited paper2015In: Proceesings of SPIE, 2015, Vol. 9649Conference paper (Refereed)
  • 6.
    Kihlman, Henrik
    et al.
    Linköping University, Department of Mechanical Engineering. Linköping University, The Institute of Technology.
    Loser, Raimund
    Leica Geosystems AG.
    6DOF metrology-integrated robot control2003Conference paper (Refereed)
    Abstract [en]

    This paper describes ongoing research into Metrology-integrated robot control. The research is a part of an ongoing EU funded aircraft industry project – ADFAST*. The ADFAST project tries to implement the use of industrial robots in low-volume production, high-demand-on-accuracy operations and for dynamic force compensation. To detect and compensate deflection in industrial robots during a process, the robot uses a metrology system. The metrology system supervises the tool center point of the robot as it executes its processes. Leica has recently released a new metrology system; the LTD800, which measures distances with laser interferometry and can simultaneously measure orientation of targets, through photogrammetry, using an additional camera on top of the measuring unit. This paper will describe theory and results from tests performed on integrating the LTD800 with the robot.

  • 7.
    Heimann, Mikael
    et al.
    University of Bergen, Norway.
    Nilheim, Katarina
    Göteborg University, Sweden.
    6-month-olds and delayed actions: An early sign of an early explicit memory?2004In: Cogniţie, Creier, Comportament/Cognition, Brain, Behavior, ISSN 1224-8398, Vol. VIII, no 3-4, 249-254 p.Article in journal (Refereed)
    Abstract [en]

    In 1996 Barr, Dowden and Hayne reported that 6 month old infants imitate new actions with objects after a substantial delay. This is a finding in need of independent replications and the study reported here presents one such attempt. Forty-five 6 months old Swedish infants (22 girls) participated in the study. They were randomly assigned to either an experimental (n=30) or acontrol condition (n=15). The procedure replicates the method used by Barret al. with one exception: The imposed delay was 10 minutes instead of 24 hours. Overall it was found that the children in the imitation group displayed significantly more target acts than the children in the control group and it is concluded that infants are capable of using deferred imitation as means for learning new actions already at 6 months.

  • 8.
    Zhang, Dai
    et al.
    Linköping University, Department of Electrical Engineering. Linköping University, Faculty of Science & Engineering. Catena Wireless Elect AB, Sweden.
    Alvandpour, Atila
    Linköping University, Department of Electrical Engineering, Integrated Circuits and Systems. Linköping University, Faculty of Science & Engineering.
    A 12.5-ENOB 10-kS/s Redundant SAR ADC in 65-nm CMOS2016In: IEEE Transactions on Circuits and Systems - II - Express Briefs, ISSN 1549-7747, E-ISSN 1558-3791, Vol. 63, no 3, 244-248 p.Article in journal (Refereed)
    Abstract [en]

    This brief describes a 14-b 10-kS/s successive approximation register analog-to-digital converter (ADC) for biomedical applications. In order to achieve enhanced linearity, a uniform-geometry nonbinary-weighted capacitive digital-to-analog converter is implemented. In addition, a secondary-bit approach to dynamically shift decision levels for error correction is employed. To reduce the power consumption, the ADC also features a power-optimized comparator with bias control. Prototyped in a 65-nm CMOS process, the ADC consumes 1.98 mu W and provides an effective number of bit (ENOB) of 12.5 b at 0.8 V while occupying an active area of 0.28 mm(2).

  • 9.
    Wedajo, W.
    et al.
    Armauer Hansen Research InstituteAddis Ababa, Ethiopia; Department of Biology, Jimma UniversityJimma, Ethiopia.
    Schön, Thomas
    Linköping University, Department of Clinical and Experimental Medicine, Division of Microbiology and Molecular Medicine. Linköping University, Faculty of Health Sciences. Department of Infectious Diseases and Microbiology, Kalmar County HospitalKalmar, Sweden.
    Bedru, A.
    Armauer Hansen Research InstituteAddis Ababa, Ethiopia.
    Kiros, T.
    Armauer Hansen Research InstituteAddis Ababa, Ethiopia.
    Hailu, E.
    Armauer Hansen Research Institute Addis Ababa, Ethiopia.
    Mebrahtu, T.
    Armauer Hansen Research Institute Addis Ababa, Ethiopia.
    Yamuah, L.
    Armauer Hansen Research Institute Addis Ababa, Ethiopia.
    Angeby, K.
    Department of Clinical Microbiology MTC, Karolinska Hospital, Karolinska University HospitalStockholm, Sweden.
    Werngren, J.
    Department of Preparedness, Unit of Highly Pathogenic Microorganisms, Swedish Institute for Communicable Disease Control (SMI)Solna, Sweden.
    Onyebujoh, P.
    World Health Organization, Regional Office for Africa, Inter-country Support Team for East0/Southern AfricaHarare, Zimbabwe.
    Dagne, K.
    Addis Ababa University, Faculty of Life SciencesAddis Ababa, Ethiopia.
    Aseffa, A.
    Armauer Hansen Research Institute Addis Ababa, Ethiopia.
    A 24-well plate assay for simultaneous testing of first and second line drugs against Mycobacterium tuberculosis in a high endemic setting2014In: BMC Research Notes, ISSN 1756-0500, Vol. 7, no 1, 512- p.Article in journal (Refereed)
    Abstract [en]

    Background: Early detection of drug resistance is one of the priorities of tuberculosis (TB) control programs as drug resistance is increasing. New molecular assays are only accessible for a minority of the second line drugs and their availability in high endemic settings is also hampered by high cost and logistic challenges. Therefore, we evaluated a previously developed method for drug susceptibility testing (DST) including both first- and second line anti-TB drugs for use in high endemic areas. Results: Baseline mycobacterial isolates from 78 consecutive pulmonary TB patients from Addis Ababa, Ethiopia who were culture positive for Mycobacterium tuberculosis at the end of a two-month directly observed treatment short course (DOTS) were included. The isolates were simultaneously tested for isoniazid, rifampicin, ethambutol, streptomycin, amikacin, kanamycin, capreomycin, ofloxacin, moxifloxacin, ethionamide and para-aminosalicylic acid susceptibility using the indirect proportion method adopted for 24-well agar plates containing Middlebrook 7H10 medium. Applying the 24-well plate assay, 43 (55.1%) isolates were resistant to one or more of the first line drugs tested (isoniazid, rifampicin and ethambutol). MDR-TB was identified in 20.5% of this selected group and there was a perfect correlation for rifampicin resistance with the results from the genotype MTBDRplus assay. All isolates were susceptible to aminoglycosides and fluoroquinolones in agreement with the genotype MTBDRsl assay. The only tested second line drug associated to resistance was ethionamide (14.1% resistant). The method was reproducible with stable results for internal controls (one multi-drug resistant (MDR) and one pan-susceptible strain (H37Rv) and DST results could be reported at two weeks. Conclusions: The 24-well plate method for simultaneous DST for first- and second line drugs was found to be reproducible and correlated well to molecular drug susceptibility tests. It is likely to be useful in high-endemic areas for surveillance as well as for the detection of second line drug resistance in targeted groups such as in those who fail empirical MDR treatment.

  • 10.
    Sundström, Timmy
    et al.
    Linköping University, The Institute of Technology. Linköping University, Department of Electrical Engineering, Electronic Devices.
    Alvandpour, Atila
    Linköping University, The Institute of Technology. Linköping University, Department of Electrical Engineering, Electronic Devices.
    A 2.5-GS/s 30-mW 4-bit flash ADC in 90nm CMOS2008In: NORCHIP, IEEE , 2008, 264-267 p.Conference paper (Refereed)
    Abstract [en]

    A 2.5 GS/s flash ADC, fabricated in 90 nm CMOS, avoids traditional power, speed and accuracy trade-offs by using comparator redundancy with power-gating capabilities. Redundancy removes the need to control comparator offsets, allowing the large process-variation induced mismatch of small devices in nanometer technologies. This enables the use of small-sized, ultra-low-power comparators. Measurement results show that the ADC dissipates 30 mW at 1.2 V. With 63 gate-able comparators, the ADC achieves 4.0 effective number of bits.

  • 11.
    Clark, Charlotte
    et al.
    Queen Mary University of London, England .
    Sörqvist, Patrik
    Linköping University, Faculty of Arts and Sciences. Linköping University, Department of Behavioural Sciences and Learning.
    A 3 year update on the influence of noise on performance and behavior2012In: Noise & Health, ISSN 1463-1741, Vol. 14, no 61, 292-296 p.Article in journal (Refereed)
    Abstract [en]

    The effect of noise exposure on human performance and behavior continues to be a focus for research activities. This paper reviews developments in the field over the past 3 years, highlighting current areas of research, recent findings, and ongoing research in two main research areas: Field studies of noise effects on childrens cognition and experimental studies of auditory distraction. Overall, the evidence for the effects of external environmental noise on childrens cognition has strengthened in recent years, with the use of larger community samples and better noise characterization. Studies have begun to establish exposure-effect thresholds for noise effects on cognition. However, the evidence remains predominantly cross-sectional and future research needs to examine whether sound insulation might lessen the effects of external noise on childrens learning. Research has also begun to explore the link between internal classroom acoustics and childrens learning, aiming to further inform the design of the internal acoustic environment. Experimental studies of the effects of noise on cognitive performance are also reviewed, including functional differences in varieties of auditory distraction, semantic auditory distraction, individual differences in susceptibility to auditory distraction, and the role of cognitive control on the effects of noise on understanding and memory of target speech materials. In general, the results indicate that there are at least two functionally different types of auditory distraction: One due to the interruption of processes (as a result of attention being captured by the sound), another due to interference between processes. The magnitude of the former type is related to individual differences in cognitive control capacities (e.g., working memory capacity); the magnitude of the latter is not. Few studies address noise effects on behavioral outcomes, emphasizing the need for researchers to explore noise effects on behavior in more detail.

  • 12.
    Zhang, Dai
    et al.
    Linköping University, Department of Electrical Engineering, Electronic Devices. Linköping University, The Institute of Technology.
    Alvandpour, Atila
    Linköping University, Department of Electrical Engineering, Electronic Devices. Linköping University, The Institute of Technology.
    A 3-nW 9.1-ENOB SAR ADC at 0.7 V and 1 kS/s2012In: ESSCIRC, 2012, Institute of Electrical and Electronics Engineers , 2012, 369-372 p.Conference paper (Refereed)
    Abstract [en]

    This paper presents a 10-bit SAR ADC in 65 nm CMOS for medical implant applications. The ADC consumes 3-nW power and achieves 9.1 ENOB at 1 kS/s. The ultra-low-power consumption is achieved by using an ADC architecture with maximal simplicity, a small split-array capacitive DAC, a bottom-plate sampling approach reducing charge injection error and allowing full-range input sampling without extra voltage sources, and a latch-based SAR control logic resulting in reduced power and low transistor count. Furthermore, a multi-Vt circuit design approach allows the ADC to meet the target performance with a single supply voltage of 0.7 V. The ADC achieves a FOM of 5.5 fJ/conversion-step. The INL and DNL errors are 0.61 LSB and 0.55 LSB, respectively.

  • 13.
    Zhang, Dai
    et al.
    Linköping University, Department of Electrical Engineering, Electronic Devices.
    Alvandpour, Atila
    Linköping University, Department of Electrical Engineering, Electronic Devices.
    A 3-nW 9.1-ENOB SAR ADC at 0.7 V and 1 kS/s2013Conference paper (Other academic)
    Abstract [en]

    This paper presents a 10-bit SAR ADC in 65 nm CMOS for medical implant applications. The ADC consumes 3-nW power and achieves 9.1 ENOB at 1 kS/s. The ultra-low-power consumption is achieved by using an ADC architecture with maximal simplicity, a small split-array capacitive DAC, a bottom-plate sampling approach reducing charge injection error and allowing full-range input sampling without extra voltage sources, and a latch-based SAR control logic resulting in reduced power and low transistor count. Furthermore, a multi-Vt circuit design approach allows the ADC to meet the target performance with a single supply voltage of 0.7 V. The ADC achieves a FOM of 5.5 fJ/conversion-step. The INL and DNL errors are 0.61 LSB and 0.55 LSB, respectively.

  • 14.
    Lindgren, Christer
    et al.
    Linköping University, Department of Clinical and Experimental Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Sinnescentrum, Department of Oral Surgery UHL.
    Mordenfeld, Arne
    Department of Oral and Maxillofacial Surgery, Gävle, County Hospital, Sweden/Dept of Biomaterials, Institute of Clinical Sciences, Göteborg University, Sweden.
    Johansson, CB
    School of Health and Medical Sciences, Örebro University, Örebro, Sweden.
    Hallman, Mats
    Department of Oral and Maxillofacial Surgery, Gävle, County Hospital, Sweden/Department of Oral & Maxillofacial Surgery, Umeå University, Umeå Sweden and Center for Research and Development, Uppsala University/Gävleborg County Council, Sweden.
    A 3-year clinical follow-up of implants placed in 2 differentbiomaterials used for sinus augmentationManuscript (preprint) (Other academic)
    Abstract [en]

    Purpose: The aims of the present study were to compare a novel biphasic calcium phosphate (BCP) with deproteinized bovine bone (DBB) used for maxillary sinus floor augmentation (MSFA) in a split mouth design, and to perform a clinical follow-up of placed dental implants.

    Material and Methods: Nine completely edentulous patients and two partially edentulous patients with a mean age of 67 years requiring bilateral sinus augmentation were included in the study. The patients were randomized for augmentation with BCP (test) and DBB (control) in the contralateral side. After 8 months of graft healing, 62 implants with an SLActive® surface (Strauman®, Basel, Switzerland) were placed. After 3 years of graft healing core biopsies were obtained from the grafted areas for histological and histomorphometrical analysis. After 3 years of functional implant loading, implant survival/success rate, clinical indexes, radiographical examination and resonance frequency analysis (RFA) wereperformed.

    Results: The mean values of the area of newly formed bone in the biopsies was 29% ±14.3% and 32% ± 18.0% for BCP and DBB respectively and graft particles in contact with bone in the BCP group was 38% ± 10.9% compared to 44% ± 12.1% for the DBB group, showing no significant differences between the groups. The mean values of the area of BCP particles and DBB particles were 20% ± 7.5% and 24% ± 13.5% respectively (non-significant).

    Irrespective of particles used, one dental implant was lost from each group, giving an overall implant survival rate of 96.8% after 3-years of loading. Conclusion: The results of this prospective 3-year clinical and histological follow up demonstrated a similar amount of newly formed bone irrespectively of the used biomaterial. The choice of biomaterial does not seem to influence the survival rates of the implants.

  • 15.
    Lindgren, Christer
    et al.
    Linköping University, Department of Clinical and Experimental Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Sinnescentrum, Department of Oral Surgery UHL.
    Mordenfeld, Arne
    Gävle County Hospital, Sweden Gothenburg University, Sweden .
    Johansson, Carina B
    University of Örebro, Sweden .
    Hallman, Mats
    Gävle County Hospital, Sweden Umeå University, Sweden Uppsala University, Sweden .
    A 3-Year Clinical Follow-up of Implants Placed in Two Different Biomaterials Used for Sinus Augmentation2012In: International Journal of Oral & Maxillofacial Implants, ISSN 0882-2786, Vol. 27, no 5, 1151-1162 p.Article in journal (Refereed)
    Abstract [en]

    Purpose: The aims of the present study were to compare a novel biphasic calcium phosphate (BCP) with deproteinized bovine bone (DBB) for maxillary sinus floor augmentation in a split-mouth design and to perform a clinical follow-up of dental implants placed in the augmented sinuses. Materials and Methods: Partially or completely edentulous patients requiring bilateral sinus augmentation were included in the study. The patients were randomized for augmentation with BCP (test) and DBB (control) in the contralateral side. Eight months after grafting, dental implants were placed. After 3 years of graft healing, core biopsy specimens were obtained from the grafted areas for histologic and histomorphometric analyses. After 3 years of functional implant loading, implant survival/success rates and clinical indices were assessed and radiographic examination and resonance frequency analysis were performed. Results: Nine completely edentulous patients and two partially edentulous patients (mean age, 67 years) who required bilateral sinus augmentation were included in the study, and 62 implants were placed. The mean values for the area of newly formed bone in the retrieved specimens were 29% +/- 14.3% and 32% +/- 18.0% for BCP and DBB, respectively; the percentage of graft particles in contact with bone was 38% +/- 10.9% in the BCP group and 44% +/- 12.1% in the DBB group (no statistical significant differences between groups). The mean values for the area of BCP particles and DBB particles were 20% +/- 7.5% and 24% +/- 13.5%, respectively (difference not significant). One dental implant was lost from each group, resulting in an overall implant survival rate of 96.8% after 3 years of loading. Conclusion: After 3 years, a similar amount of newly formed bone was present regardless of the biomaterial used. The choice of biomaterial did not seem to influence implant survival rates.

  • 16.
    Garrido Gálvez, Mario
    et al.
    Linköping University, Department of Electrical Engineering, Computer Engineering. Linköping University, Faculty of Science & Engineering.
    Angel Sanchez, Miguel
    University of Politecn Madrid, Spain.
    Luisa Lopez-Vallejo, Maria
    University of Politecn Madrid, Spain.
    Grajal, Jesus
    University of Politecn Madrid, Spain.
    A 4096-Point Radix-4 Memory-Based FFT Using DSP Slices2017In: IEEE Transactions on Very Large Scale Integration (vlsi) Systems, ISSN 1063-8210, E-ISSN 1557-9999, Vol. 25, no 1, 375-379 p.Article in journal (Refereed)
    Abstract [en]

    This brief presents a novel 4096-point radix-4 memory-based fast Fourier transform (FFT). The proposed architecture follows a conflict-free strategy that only requires a total memory of size N and a few additional multiplexers. The control is also simple, as it is generated directly from the bits of a counter. Apart from the low complexity, the FFT has been implemented on a Virtex-5 field programmable gate array (FPGA) using DSP slices. The goal has been to reduce the use of distributed logic, which is scarce in the target FPGA. With this purpose, most of the hardware has been implemented in DSP48E. As a result, the proposed FPGA is efficient in terms of hardware resources, as is shown by the experimental results.

  • 17.
    Sundström, Timmy
    et al.
    Linköping University, Department of Electrical Engineering, Electronic Devices. Linköping University, The Institute of Technology.
    Alvandpour, Atila
    Linköping University, Department of Electrical Engineering, Electronic Devices. Linköping University, The Institute of Technology.
    A 4-bit 2.5-GS/s 30-mW Flash ADC in 90nm CMOS2009In: Swedish System on Chip Conference, SSoCC, Arild, May 4-5, Lunds universitet, 2009Conference paper (Other academic)
    Abstract [en]

    A 2.5 GS/s flash ADC, fabricated in 90nm CMOS,avoids traditional power, speed and accuracy trade-offs by usingcomparator redundancy with power-gating capabilities.Redundancy removes the need to control comparator offsets,allowing the large process-variation induced mismatch of smalldevices in nanometer technologies. This enables the use of smallsized,ultra-low-power comparators. Measurement results showthat the ADC dissipates 30 mW at 1.2 V. With 63 gate-ablecomparators, the ADC achieves 4.0 effective number of bits.

  • 18.
    Sundström, Timmy
    et al.
    Linköping University, Department of Electrical Engineering, Electronic Devices. Linköping University, The Institute of Technology.
    Alvandpour, Atila
    Linköping University, Department of Electrical Engineering, Electronic Devices. Linköping University, The Institute of Technology.
    A 6‐bit 2.5‐GS/s Flash ADC using Comparator Redundancy for Low Power in 90nm CMOS2010In: Analog Integrated Circuits and Signal Processing, ISSN 0925-1030, E-ISSN 1573-1979, Vol. 64, no 3, 215-222 p.Article in journal (Refereed)
    Abstract [en]

    A 2.5 GS/s flash ADC, fabricated in 90nm CMOS utilizes comparator redundancy to avoid traditional power, speed and accuracy trade‐offs. The redundancy removes the need to control comparator offsets, allowing the large process‐variation induced mismatch of small devices in nanometer technologies. This enables the use of small‐sized, ultra‐low‐power comparators with clock‐gating capabilities in order to reduce the power dissipation. The chosen calibration method enables an overall low‐power solution and measurement results show that the ADC dissipates 30 mW at 1.2 V. With 63 comparators, the ADC achieves 3.9 effective number of bits.

  • 19.
    Härkegård, Ola
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Glad, Torkel
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Backstepping Design for Flight Path Angle Control2000Report (Other academic)
    Abstract [en]

    A nonlinear approach to flight path angle control is presented. Using backstepping, a globally stabilizing control law is derived. Although the nonlinear nature of the lift force is considered, the pitching moment to be produced is only linear in the measured states. Thus, the resulting control law is much simpler than if feedback linearization had been used. The free parameters that spring from the backstepping design are used to achieve a desired linear behavior around the operating point.

  • 20.
    Härkegård, Ola
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Glad, Torkel
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Backstepping Design for Flight Path Angle Control2000In: Proceedings of the 39th IEEE Conference on Decision and Control, 2000, 3570-3575 p.Conference paper (Refereed)
    Abstract [en]

    A nonlinear approach to flight path angle control is presented. Using backstepping, a globally stabilizing control law is derived. Although the nonlinear nature of the lift force is considered, the pitching moment to be produced is only linear in the measured states. Thus, the resulting control law is much simpler than if feedback linearization had been used. The free parameters that spring from the backstepping design are used to achieve a desired linear behavior around the operating point.

  • 21.
    Mahmoud, Nawrous Ibrahim
    Linköping University, Department of Electrical Engineering.
    A Backstepping Design of a Control System for a Magnetic Levitation System2003Independent thesis Basic level (professional degree)Student thesis
    Abstract [en]

    The subject of this thesis is the design of a control law for a magnetic levitation system, which in this case is the system 33-210. The method used is backstepping technique and specifically adaptive observer backstepping due to parameter uncertainties and lack of access to all the states of the system. The second state of the system, the speed of the steel ball, was estimated by a reduced order observer. The model used gave us the opportunity to estimate a parameter which in the literature is denoted virtual control coefficient. Backstepping method gives us a rather straight forward way to design the controlling unit for a system with these properties. Stabilization of the closed-loop system is achieved by incorporating a Lypapunov function, which were chose a quadratic one in this thesis. If thederivative of this function is rendered negative definite by the control law, then we achieve stability. The results of the design were evaluated in simulations and real-time measurements by testing the tracking performance of the system. The simulation results were very promising and the validations in real-time were satisfying. Note that this has been done in previous studies; the new aspect here is the limitation of the voltage input. The real-time results showed that the parameter estimation converges only locally.

  • 22.
    Hu, Xiao-Li
    et al.
    Chinese Academy of Sciences, China.
    Schön, Thomas
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Ljung, Lennart
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Basic Convergence Result for Particle Filtering2007Report (Other academic)
    Abstract [en]

    The basic nonlinear filtering problem for dynamical systems is considered. Approximating the optimal filter estimate by particle filter methods has become perhaps the most common and useful method in recent years. Many variants of particle filters have been suggested, and there is an extensive literature on the theoretical aspects of the quality of the approximation. Still a clear cut result that the approximate solution, for unbounded functions, converges to the true optimal estimate as the number of particles tends to infinity seems to be lacking. It is the purpose of this contribution to give such a basic convergence result for a rather general class of unbounded functions. Furthermore, a general framework, including many of the particle filter algorithms as special cases, is given.

  • 23.
    Hu, Xiao-Li
    et al.
    Chinese Academy of Sciences, China.
    Schön, Thomas
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Ljung, Lennart
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Basic Convergence Result for Particle Filtering2007Report (Other academic)
    Abstract [en]

    The basic nonlinear filtering problem for dynamical systems is considered. Approximating the optimal filter estimate by particle filter methods has become perhaps the most common and useful method in recent years. Many variants of particle filters have been suggested, and there is an extensive literature on the theoretical aspects of the quality of the approximation. Still a clear cut result that the approximate solution, for unbounded functions, converges to the true optimal estimate as the number of particles tends to infinity seems to be lacking. It is the purpose of this contribution to give such a basic convergence result for a rather general class of unbounded functions. Furthermore, a general framework, including many of the particle filter algorithms as special cases, is given.

  • 24.
    Hu, Xiao-Li
    et al.
    China Jiliang University, China.
    Schön, Thomas
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Ljung, Lennart
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Basic Convergence Result for Particle Filtering2007In: Proceedings of the 7th IFAC Symposium on Nonlinear Control Systems, 2007, 288-293 p.Conference paper (Refereed)
    Abstract [en]

    The basic nonlinear filtering problem for dynamical systems is considered. Approximating the optimal filter estimate by particle filter methods has become perhaps the most common and useful method in recent years. Many variants of particle filters have been suggested, and there is an extensive literature on the theoretical aspects of the quality of the approximation. Still, a clear cut result that the approximate solution, for unbounded functions, converges to the true optimal estimate as the number of particles tends to infinity seems to be lacking. It is the purpose of this contribution to give such a basic convergence result.  

  • 25.
    Hu, Xiao-Li
    et al.
    Chinese Academy of Sciences, China.
    Schön, Thomas
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Ljung, Lennart
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Basic Convergence Result for Particle Filtering2008In: IEEE Transactions on Signal Processing, ISSN 1053-587X, E-ISSN 1941-0476, Vol. 56, no 4, 1337-1348 p.Article in journal (Refereed)
    Abstract [en]

    The basic nonlinear filtering problem for dynamical systems is considered. Approximating the optimal filter estimate by particle filter methods has become perhaps the most common and useful method in recent years. Many variants of particle filters have been suggested, and there is an extensive literature on the theoretical aspects of the quality of the approximation. Still a clear-cut result that the approximate solution, for unbounded functions, converges to the true optimal estimate as the number of particles tends to infinity seems to be lacking. It is the purpose of this contribution to give such a basic convergence result for a rather general class of unbounded functions. Furthermore, a general framework, including many of the particle filter algorithms as special cases, is given.

  • 26.
    Özkan, Emre
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Lundquist, Christian
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Gustafsson, Fredrik
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Bayesian Approach to Jointly Estimate Tire Radii and Vehicle Trajectory2011In: Proceedings of the International IEEE Conference on Intelligent Transportation Systems, Washington DC, USA: IEEE conference proceedings, 2011, 1-6 p.Conference paper (Refereed)
    Abstract [en]

    High-precision estimation of vehicle tire radii is considered, based on measurements on individual wheel speeds and absolute position from a global navigation satellite system (GNSS). The wheel speed measurements are subject to noise with time-varying covariance that depends mainly on the road surface. The novelty lies in a Bayesian approach to estimate online the time-varying radii and noise parameters using a marginalized particle filter, where no model approximations are needed such as in previously proposed algorithms based on the extended Kalman filter. Field tests show that the absolute radius can be estimated with millimeter accuracy, while the relative wheel radius on one axle is estimated with submillimeter accuracy.

  • 27.
    Isaksson, Alf
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Gustafsson, Fredrik
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Bayesian Approach to Manoeuvre Tracking and Detection1992Report (Other academic)
  • 28.
    Isaksson, Alf
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Gustafsson, Fredrik
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Bayesian Approach to Manoeuvre Tracking and Detection1993In: Proceedings of the 12th IFAC World Congress, 1993Conference paper (Refereed)
  • 29.
    Bergman, Niclas
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Bayesian Approach to Terrain-Aided Navigation1996Report (Other academic)
    Abstract [en]

    The terrain-aided navigation problem is a highly nonlinear estimation problem with application to aircraft navigation and missile guidance. In this work the Bayesian approach is used to estimate the aircraft position. With a quantization of the state space an implementable algorithm is found. Problems with low excitation, rough terrain and parallel position hypothesis are handled in a reliable way. The algorithm is evaluated using simulations on real terrain databases.

  • 30.
    Bergman, Niclas
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Bayesian Approach to Terrain-Aided Navigation1997In: Proceedings of the 11th IFAC Symposium on System Identification, 1997, 1531-1536 p.Conference paper (Refereed)
    Abstract [en]

    The terrain-aided navigation problem is a highly nonlinear estimation problem with application to aircraft navigation and missile guidance. In this work the Bayesian approach is used to estimate the aircraft position. With a quantization of the state space an implementable algorithm is found. Problems with low excitation, rough terrain and parallel position hypothesis are handled in a reliable way. The algorithm is evaluated using simulations on real terrain databases.

  • 31.
    Bergman, Niclas
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Bayesian Approach to Terrain-Aided Navigation II1997Report (Other academic)
    Abstract [en]

    The terrain-aided navigation problem is a highly nonlinear estimation problem with application to aircraft navigation and missile guidance. In this work the Bayesian approach is used to estimate the aircraft position. With a quantization of the state space an implementable algorithm is found. Problems with low excitation, rough terrain and parallel position hypothesis are handled in a reliable way. The algorithm is evaluated using simulations on real terrain databases.

  • 32.
    Lindström, Tom
    et al.
    Linköping University, Department of Physics, Chemistry and Biology, Theoretical Biology. Linköping University, Faculty of Science & Engineering. Colorado State University, CO 80523 USA; US National Institute Heatlh, MD USA; University of Exeter, England.
    Tildesley, Michael
    US National Institute Heatlh, MD USA; University of Nottingham, England.
    Webb, Colleen
    Colorado State University, CO 80523 USA; US National Institute Heatlh, MD USA.
    A Bayesian Ensemble Approach for Epidemiological Projections2015In: PloS Computational Biology, ISSN 1553-734X, E-ISSN 1553-7358, Vol. 11, no 4, e1004187- p.Article in journal (Refereed)
    Abstract [en]

    Mathematical models are powerful tools for epidemiology and can be used to compare control actions. However, different models and model parameterizations may provide different prediction of outcomes. In other fields of research, ensemble modeling has been used to combine multiple projections. We explore the possibility of applying such methods to epidemiology by adapting Bayesian techniques developed for climate forecasting. We exemplify the implementation with single model ensembles based on different parameterizations of the Warwick model run for the 2001 United Kingdom foot and mouth disease outbreak and compare the efficacy of different control actions. This allows us to investigate the effect that discrepancy among projections based on different modeling assumptions has on the ensemble prediction. A sensitivity analysis showed that the choice of prior can have a pronounced effect on the posterior estimates of quantities of interest, in particular for ensembles with large discrepancy among projections. However, by using a hierarchical extension of the method we show that prior sensitivity can be circumvented. We further extend the method to include a priori beliefs about different modeling assumptions and demonstrate that the effect of this can have different consequences depending on the discrepancy among projections. We propose that the method is a promising analytical tool for ensemble modeling of disease outbreaks.

  • 33.
    Moberg, Stig
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Öhr, Jonas
    ABB AB, Crane Systems, Sweden.
    Gunnarsson, Svante
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Benchmark Problem for Robust Control of a Multivariable Nonlinear Flexible Manipulator2008Report (Other academic)
    Abstract [en]

    A benchmark problem for robust feedback control of a manipulator is presented. The system to be controlled is an uncertain nonlinear two link manipulator with elastic gear transmissions. The gear transmission is described by nonlinear friction and elasticity. The system is uncertain according to a parametric uncertainty description and due to uncertain disturbances affecting both the motors and the tool. The system should be controlled by a discrete-time controller that optimizes performance for given robustness requirements. The control problem concerns only disturbance rejection. The proposed model is validated by experiments on a real industrial manipulator.

  • 34.
    Moberg, Stig
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Öhr, Jonas
    ABB AB, Crane Systems, Sweden.
    Gunnarsson, Svante
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Benchmark Problem for Robust Control of a Multivariable Nonlinear Flexible Manipulator2008In: Proceedings of the 17th IFAC World Congress, 2008, 1206-1211 p.Conference paper (Refereed)
    Abstract [en]

    A benchmark problem for robust feedback control of a manipulator is presented. The system to be controlled is an uncertain nonlinear two link manipulator with elastic gear transmissions. The gear transmission is described by nonlinear friction and elasticity. The system is uncertain according to a parametric uncertainty description and due to uncertain disturbances affecting both the motors and the tool. The system should be controlled by a discrete-time controller that optimizes performance for given robustness requirements. The control problem concerns only disturbance rejection. The proposed model is validated by experiments on a real industrial manipulator.

  • 35.
    Moberg, Stig
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Öhr, Jonas
    ABB AB, Sweden.
    Gunnarsson, Svante
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Benchmark Problem for Robust Feedback Control of a Flexible Manipulator2009In: IEEE Transactions on Control Systems Technology, ISSN 1063-6536, E-ISSN 1558-0865, Vol. 17, no 6, 1398-1405 p.Article in journal (Refereed)
    Abstract [en]

    A benchmark problem for robust feedback control of a flexible manipulator is presented. The system to be controlled is a four-mass system subject to input saturation, nonlinear gear elasticity, model uncertainties, and load disturbances affecting both the motor and the arm. The system should be controlled by a discrete-time controller that optimizes performance for given robustness requirements. Four suggested solutions are presented, and even though the solutions are based on different design methods, they give comparable results.

  • 36.
    Moberg, Stig
    et al.
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Öhr, Jonas
    ABB AB, Sweden.
    Gunnarsson, Svante
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Benchmark Problem for Robust Feedback Control of a Flexible ManipulatorA benchmark problem for robust feedback control of a flexible manipulator2007Report (Other (popular science, discussion, etc.))
    Abstract [en]

    A benchmark problem for robust feedback control of a flexible manipulator is presented. The system to be controlled is a four-mass system subject to input saturation, nonlinear gear elasticity, model uncertainties, and load disturbances affecting both the motor and the arm. The system should be controlled by a discrete-time controller that optimizes performance for given robustness requirements. Four suggested solutions are presented, and even though the solutions are based on different design methods, they give comparable results.

  • 37.
    Curescu, C.
    et al.
    Ericsson Research, Torshamnsgatan 23, Kista, 164 83 Stockholm, Sweden.
    Nadjm-Tehrani, Simin
    Linköping University, The Institute of Technology. Linköping University, Department of Computer and Information Science, RTSLAB - Real-Time Systems Laboratory.
    A bidding algorithm for optimized utility-based resource allocation in ad hoc networks2008In: IEEE Transactions on Mobile Computing, ISSN 1536-1233, Vol. 7, no 12, 1397-1414 p.Article in journal (Refereed)
    Abstract [en]

    This paper proposes a scheme for bandwidth allocation in wireless ad hoc networks. The quality-of-service (QoS) levels for each end-to-end flow are expressed using a resource-utility function, and our algorithms aim to maximize aggregated utility. The shared channel is modeled as a bandwidth resource defined by maximal cliques of mutual interfering links. We propose a novel resource allocation algorithm that employs an auction mechanism in which flows are bidding for resources. The bids depend both on the flow's utility function and the intrinsically derived shadow prices. We then combine the admission control scheme with a utility-aware on-demand shortest path routing algorithm where shadow prices are used as a natural distance metric. As a baseline for evaluation, we show that the problem can be formulated as a linear programming (LP) problem. Thus, we can compare the performance of our distributed scheme to the centralized LP solution, registering results very close to the optimum. Next, we isolate the performance of price-based routing and show its advantages in hotspot scenarios, and also propose an asynchronous version that is more feasible for ad hoc environments. Further experimental evaluation compares our scheme with the state of the art derived from Kelly's utility maximization framework and shows that our approach exhibits superior performance for networks with increased mobility or less frequent allocations. © 2008 IEEE.

  • 38.
    Wermelin, Karin
    et al.
    Linköping University, Department of Clinical and Experimental Medicine, Orthopaedics and Sports Medicine . Linköping University, Faculty of Health Sciences.
    Tengvall, Pentti
    Linköping University, Department of Physics, Chemistry and Biology, Applied Physics . Linköping University, The Institute of Technology.
    Aspenberg, Per
    Linköping University, Department of Clinical and Experimental Medicine, Orthopaedics and Sports Medicine . Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Orthopaedic Centre, Department of Orthopaedics Linköping.
    A bisphosphonate coating improves the bony fixation of stainless steel screws in ovariectomized rats2008Article in journal (Refereed)
    Abstract [en]

    Background: Bisphosphonate coatings improve the fixation of implants in bone. Stainless steels screws inserted in the rat tibia become encapsulated by new bone if they are coated with bisphosphonates in a crosslinked fibrinogen matrix. Thereby, the coating leads to a gradual increase in pull-out force. We now investigate if this bisphosphonate coating is capable to improve the mechanical fixation also in osteoporotic bone.

    Methods: Stainless steel screws were coated with a thin crosslinked fibrinogen matrix. With EDC/NHS coupling technique, pamidronate was bound to carboxylic groups and ibandronate was adsorbed in the fibrinogen matrix. Uncoated stainless steel screws and bisphosphonatecoated screws were inserted bilaterally in the proximal tibia in 10 ovariectomized and 10 sham operated rats. At 2 weeks pull-out force and energy was measured.

    Results: In the ovariectomized rats, pull-out force was 53 % higher for bisphosphonate coated screws compared to control screws. Energy was 44 % higher. The sham operated rats showed a higher variation, and no effect of the coating was found.

    Conclusion: The coating was sufficient to improve fixation in ovariectomized rats

  • 39.
    Ceragioli, Francesca
    et al.
    Politécnico di Torino, Dip. di Mathematica.
    Lindmark, Gustav
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, Faculty of Science & Engineering.
    Veibäck, Clas
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, Faculty of Science & Engineering.
    Wahlström, Niklas
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, Faculty of Science & Engineering.
    Lindfors, Martin
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, Faculty of Science & Engineering.
    Altafini, Claudio
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, Faculty of Science & Engineering.
    A bounded confidence model that preserves the signs of the opinions2016In: Proceedings of the 2016 European Control Conference, Institute of Electrical and Electronics Engineers (IEEE), 2016, 543-548 p.Conference paper (Refereed)
    Abstract [en]

    The aim of this paper is to suggest a modification to the usual bounded confidence model of opinion dynamics, so that “changes of opinion” (intended as changes of the sign of the initial state) of an agent are never induced by the dynamics. In order to do so, a bipartite consensus model is used, endowing it with a confidence range. The resulting signed bounded confidence model has a state-dependent connectivity and a behavior similar to its standard counterpart, but in addition it preserves the sign of the opinions by “repelling away” opinions localized near the origin but on different sides with respect to 0.

  • 40.
    Eklund, Anders
    et al.
    Linköping University, Center for Medical Image Science and Visualization (CMIV). Linköping University, Department of Biomedical Engineering, Medical Informatics. Linköping University, The Institute of Technology.
    Andersson, Mats
    Linköping University, Center for Medical Image Science and Visualization (CMIV). Linköping University, Department of Biomedical Engineering, Medical Informatics. Linköping University, The Institute of Technology.
    Ohlsson, Henrik
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    Ynnerman, Anders
    Linköping University, Center for Medical Image Science and Visualization (CMIV). Linköping University, Department of Science and Technology, Visual Information Technology and Applications (VITA). Linköping University, The Institute of Technology.
    Knutsson, Hans
    Linköping University, Center for Medical Image Science and Visualization (CMIV). Linköping University, Department of Biomedical Engineering, Medical Informatics. Linköping University, The Institute of Technology.
    A Brain Computer Interface for Communication Using Real-Time fMRI2010In: Proceedings of the 20th International Conference on Pattern Recognition, Los Alamitos, CA, USA: IEEE Computer Society, 2010, 3665-3669 p.Conference paper (Refereed)
    Abstract [en]

    We present the first step towards a brain computer interface (BCI) for communication using real-time functional magnetic resonance imaging (fMRI). The subject in the MR scanner sees a virtual keyboard and steers a cursor to select different letters that can be combined to create words. The cursor is moved to the left by activating the left hand, to the right by activating the right hand, down by activating the left toes and up by activating the right toes. To select a letter, the subject simply rests for a number of seconds. We can thus communicate with the subject in the scanner by for example showing questions that the subject can answer. Similar BCI for communication have been made with electroencephalography (EEG). The subject then focuses on a letter while different rows and columns of the virtual keyboard are flashing and the system tries to detect if the correct letter is flashing or not. In our setup we instead classify the brain activity. Our system is neither limited to a communication interface, but can be used for any interface where five degrees of freedom is necessary.

  • 41.
    Persson, Ulf
    et al.
    Lund University, Sweden Lundby Hospital, Sweden .
    Gullstrand, Birgitta
    Lund University, Sweden .
    Pettersson, Asa
    Lund University, Sweden .
    Sturfelt, Gunnar
    Lund University, Sweden .
    Truedsson, Lennart
    Lund University, Sweden .
    Segelmark, Mårten
    Linköping University, Department of Medical and Health Sciences, Division of Drug Research. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Center, Department of Nephrology.
    A Candidate Gene Approach to ANCA-Associated Vasculitis Reveals Links to the C3 and CTLA-4 Genes but not to the IL1-Ra And Fc gamma-RIIa Genes2013In: Kidney and Blood Pressure Research, ISSN 1420-4096, E-ISSN 1423-0143, Vol. 37, no 6, 641-648 p.Article in journal (Refereed)
    Abstract [en]

    Background/Aims: The aim of the study is to search for associations between Antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) and polymorphisms in the genes of four key molecules possibly involved in different pathogenic pathways; complement C3, CTLA-4, Fc gamma-RIIa and IL1-Ra. Patients and Methods: Patients with AAV (n=105) subgrouped as microscopic polyangiitis or granulomatosis with polyangiitis (Wegeners granulomatosis) and myeloperoxidase (MPO) or proteinase 3 (PR3) ANCA positive were compared to a control group of 200 blood donors. Polymorphisms in the genes were analysed with PCR amplification of DNA. Results: The diagnosis of AAV was confirmed in the 105 cases. The gene frequency of C3F was 0.27 in the PR3-ANCA subgroup (p=0.041) compared to 0,19 in the control group. The number of patients homozygous for the shortest 86 bp allele of CTLA-4 was significantly decreased in the whole group of patients (p=0.049). No differences were evident in the Fc gamma-RIIa and IL1-Ra polymorphisms when compared to controls, neither in the whole group of patients, nor in any of the sub-groups. Conclusion: The aberrant gene frequency of the C3F allele among PR3-ANCA positive patients and the findings with the CTLA-4 polymorphism indicates that complement may be involved in pathogenesis and that T-cell activation also is of importance in these diseases.

  • 42.
    Murugesan, Murali
    et al.
    Department of Microtechnology and Nanoscience (MC2), Chalmers University of Technology, Gothenburg, Sweden.
    Zanden, Carl
    Department of Microtechnology and Nanoscience (MC2), Chalmers University of Technology, Gothenburg, Sweden.
    Luo, Xin
    Department of Microtechnology and Nanoscience (MC2), Chalmers University of Technology, Gothenburg, Sweden; School of Mechatronics and Mechanical Engineering, Key Laboratory of New Displays and System Integration, Shanghai University, China .
    Ye, Lilei
    SHT Smart High-Tech AB, Gothenburg, Sweden.
    Jokubavicius, Valdas
    Linköping University, Department of Physics, Chemistry and Biology, Semiconductor Materials. Linköping University, The Institute of Technology.
    Syväjärvi, Mikael
    Linköping University, Department of Physics, Chemistry and Biology, Semiconductor Materials. Linköping University, The Institute of Technology.
    Liu, Johan
    Department of Microtechnology and Nanoscience (MC2), Chalmers University of Technology, Gothenburg, Sweden; School of Mechatronics and Mechanical Engineering, Key Laboratory of New Displays and System Integration, Shanghai University, China .
    A carbon fiber solder matrix composite for thermalmanagement of microelectronic devices2014In: Journal of Materials Chemistry C, ISSN 2050-7526, Vol. 2, no 35, 7184-7187 p.Article in journal (Refereed)
    Abstract [en]

    A carbon fiber based tin-silver-copper alloy matrix composite (CF-TIM) was developed via electrospinning of a mesophase pitch with polyimide and carbonization at 1000 °C, followed by sputter coating with titanium and gold, and alloy infiltration. The carbonized fibers, in film form, showed a thermal conductivity of ∼4 W m-1 K-1 and the CF-TIM showed an anisotropic thermal conductivity of 41 ± 2 W m-1 K-1 in-plane and 20 ± 3 W m-1 K-1 through-plane. The thermal contact resistance of the CF-TIM was estimated to be below 1 K mm2 W-1. The CF-TIM showed no reduction in effective through-plane thermal conductivity after 1000 temperature cycles, which indicates the potential use of CF-TIM in thermal management applications.

  • 43.
    Bengts, Elin
    Linköping University, Department of Thematic Studies, The Department of Gender Studies.
    A case study of post-earthquake consequences for women within marginalized groups in Nepal: A qualitative case study with the aim to explore the consequences for women within marginalized groups in a post-earthquake society2016Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    This report is the outcome of a case study conducted in Kathmandu, Nepal in April 2016. The purpose of the study is to investigate in the consequences of the 2015 earthquake in Nepal, from the perspective of women within socioeconomically vulnerable groups. The caste system is still practiced nearly all over Nepal and women are still facing multiple forms of discrimination. A woman belonging to the Dalits, which is the group considered to be at the bottom of the hierarchy and below the castes, have no right to control land, housing or money and are exposed to violence and forced sexual labour. The aim of the study is to shed light over how already existing discrimination leads to further examples of discrimination in the aftermath of a natural disaster and the “class-consciousness” of natural disasters. People within a society are living under different conditions and these conditions lead to different consequences when facing a natural disaster. The components of these conditions are often intertwined with each other and should therefore not be examined separately, which is why an intersectional perspective is used for this study. Furthermore, standpoint theory is used as well, to look at these issues from the viewpoint of the marginalized people of the society. Interviews were made with 6 different respondents, who are working for NGOs in and outside of Kathmandu and who through their work are coming on contact with the issues mentioned. My findings show several examples of post-earthquake consequences for women which can be linked to the strong patriarchy, the use of caste system and mistreatment from the government.

  • 44.
    Strand, Joel
    et al.
    Linköping University, Department of Management and Engineering, Production Economics.
    Strandänger, Louise
    Linköping University, Department of Management and Engineering, Production Economics.
    A case study on how an e-tailer can use a multiple criteria ABC analysis to identify risk in the selection of suppliers2016Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    Purpose – The purpose of this master thesis is to explore how an e-tailer selling bulky items can use a multiple criteria ABC analysis to make its purchasing process more effective, while balancing richness and reach, with the performance measurements of profitability, total asset turnover and inventory turnover. The purpose will be accomplished through a single case study on an e-tailer active on the Swedish furniture and home furnishing market.

    Methodology – This thesis applies a multiple criteria ABC-analysis to a single case study. The approach is semi-deductive as theory is combined with interviews on how to match and adapt theory about inventory control and purchasing with the specific requirements of an e-tailer selling bulky items.

    Findings – This thesis has resulted in a set of recommendations that aim to make the purchasing process of an e-tailer more effective. That is, capital and inventory space will be better allocated to the e-tailer’s more profitable items. Among other things, this thesis shows how dead articles can be identified and how a purchaser can prioritize more profitable articles over less profitable ones when making procurement decisions. The other recommendations are for the e-tailer to investigate the possibilities of decoupling the supply chain by keeping stock at the suppliers’ premises, to match the supplier reliability with their importance in the supply chain, and lastly to explore possibilities of drop shipment. Further, the main finding is that a comparison between the A-, B-, and C-classes and the reliability of the suppliers, highlights a gap and a possible risk. Put differently, the importance of a specific item for the business should be reflected in the choice of supplier and the multiple criteria ABC analysis is the tool to illustrate the importance.

    Keywords – E-commerce, E-tailer, richness, reach, transaction cost, ABC analysis, multiple criteria ABC, MCABC, inventory turnover ratio, supplier selection, purchasing

    Paper type – Masters thesis

  • 45.
    Lundqvist, G
    et al.
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Molecular and Clinical Medicine, Occupational and Environmental Medicine. Östergötlands Läns Landsting, Pain and Occupational Centre, Occupational and Environmental Medicine Centre.
    Axelson, Olav
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Molecular and Clinical Medicine, Occupational and Environmental Medicine. Östergötlands Läns Landsting, Pain and Occupational Centre, Occupational and Environmental Medicine Centre.
    Flodin, Ulf
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Molecular and Clinical Medicine, Occupational and Environmental Medicine. Östergötlands Läns Landsting, Pain and Occupational Centre, Occupational and Environmental Medicine Centre.
    A case-control study of fatty liver disease and organic solvent exposure.  1999In: American Journal of Industrial Medicine, ISSN 0271-3586, Vol. 35, 132-136 p.Article in journal (Refereed)
  • 46. Faresjö, Åshild
    et al.
    Grodzinsky, Ewa
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Department of Health and Society, General Practice. Östergötlands Läns Landsting, Local Health Care Services in the West of Östergötland, Unit of Research and Development in Local Health Care, County of Östergötland.
    Timpka, Toomas
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Department of Health and Society, Division of Preventive and Social Medicine and Public Health Science. Östergötlands Läns Landsting, Centre for Public Health Sciences, Centre for Public Health Sciences.
    Åkerlind, Ingemar
    Linköping University, Faculty of Health Sciences. Linköping University, Department of Department of Health and Society, National Centre for Work and Rehabilitation. Östergötlands Läns Landsting, Local Health Care Services in the West of Östergötland, Unit of Research and Development in Local Health Care, County of Östergötland.
    A case-control study of irritable bowel syndrome in primary care - female patients are seriously affected by psychosocial problems in their every day life2006In: EUPHA 14th annual conference,2006, 2006Conference paper (Other academic)
  • 47.
    Bäckman, Carl G
    et al.
    Linköping University, Department of Clinical and Experimental Medicine. Linköping University, Faculty of Health Sciences.
    Orwelius, Lotti
    Linköping University, Department of Medical and Health Sciences. Linköping University, Faculty of Health Sciences.
    Sjöberg, Folke
    Linköping University, Department of Clinical and Experimental Medicine, Burn Unit . Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Sinnescentrum, Department of Plastic Surgery, Hand surgery UHL.
    Fredrikson, Mats
    Linköping University, Department of Clinical and Experimental Medicine, Occupational and Environmental Medicine. Linköping University, Faculty of Health Sciences.
    Walther, Sten M
    Linköping University, Department of Medical and Health Sciences, Physiology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Centre, Department of Thoracic and Vascular Surgery in Östergötland.
    A case-control study of the influence of the ICU-diary concept on mastery and hopelessness six months after critical illnessManuscript (preprint) (Other academic)
    Abstract [en]

    The ICU-diary concept is associated with less post-traumatic stress syndrome and improved perceived health-related quality-of-life (HRQoL) after critical illness, but little is known about its effect on the coping- mastery process, or whether it reduces hopelessness.

    Objective: To see if the ICU-diary concept improves the patient’s ability to master his/her situation after critical illness, and if it reduces the feeling of hopelessness.

    Design: Case control study (subgroup analysis of a multi-centre study on health-related quality-of-life (HRQoL).

    Setting: Non-academic 8-bed general ICU.

    Patients: Adults admitted between March 2002 and June 2004.

    Measurements: Mastery and hopelessness were determined using validated questionnaires (the Mastery-Coping scale and a consolidated 2–item hopelessness questionnaire) which were sent home to patients 6 months after critical illness. Responses were compared between patients that received (Cases: n=38) or did not receive an ICU-diary (Controls: n=76) . Diaries were used when a long and complicated stay on the ICU was expected. Controls were matched with diary patients by gender and age. The effect of the ICU-diary was also examined using a multiple regression model.

    Results: The ICU-diary concept group scored significantly higher than the No-diary group in mastery (22.1 vs. 20.4, P<0.05) and lower in hopelessness scores (1.3 vs. 1.6, P<0.05). The positive influence of the ICU-diary disappeared after adjustment for confounding factors in a multiple regression model.

    Conclusion: We were unable to verify any positive influence of the ICU-diary concept on mastery and hopelessness 6 months after critical illness.

  • 48.
    Edström, Krister
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Causal Propagation Algorithm for Switched Bond Graphs using Bicausality1998Report (Other academic)
  • 49.
    Edström, Krister
    Linköping University, Department of Electrical Engineering, Automatic Control. Linköping University, The Institute of Technology.
    A Causal Propagation Algorithm for Switched Bond Graphs using Bicausality1999In: Proceedings of the 1999 International Conference on Bond Graph Modeling and Simulation, 1999, 77-82 p.Conference paper (Refereed)
  • 50.
    Pham, M K
    et al.
    IAEA.
    Betti, M
    IAEA.
    Povinec, P P
    Comenius University.
    Benmansour, M
    Centre Natl Energie Science and Tech Nucl, Rabat.
    Buenger, V
    Senatsverwaltung Gesundheit Umwelt and Verbraucher.
    Drefvelin, J
    Norwegian Radiation Protection Authority.
    Engeler, C
    WGMLA Radiochem.
    Flemal, J M
    Science Institute for Public Health.
    Gasco, C
    Centre Invest Energet MedioAmbient and Technology.
    Guillevic, J
    Institute Radioprotect and Surette Nucl.
    Gurriaran, R
    IRSN DEI STEME LMRE.
    Groening, M
    IAEA.
    Happel, J D
    University of Miami.
    Herrmann, J
    Bundesamt Seeschifffahrt and Hydrog.
    Klemola, S
    Radiat and Nucl Safety Author.
    Kloster, M
    Senatsverwaltung Gesundheit Umwelt and Verbraucher.
    Kanisch, G
    Johann Heinrich von Thunen Institute.
    Leonard, K
    Centre Environm Fisheries and Aquaculture Science.
    Long, S
    Radiol Protect Institute Ireland.
    Nielsen, S
    Riso Natl Lab.
    Oh, J-S
    Natl Oceanog Centre Southampton.
    Rieth, P U
    Johann Heinrich von Thunen Institute.
    Oestergren, I
    Swedish Radiat Safety Author.
    Pettersson, Håkan
    Linköping University, Department of Medical and Health Sciences, Radiation Physics. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Centre of Surgery and Oncology, Department of Radiation Physics.
    Pinhao, N
    Institute Tecnol and Nucl, Sacavem, Portugal .
    Pujol, L
    Centre Estudios Expt and Obras Publ.
    Sato, K
    Japan Chemistry Anal Centre.
    Schikowski, J
    University of Gottingen.
    Varga, Z
    Hungarian Academy of Science.
    P Vartti, V
    Radiat and Nucl Safety Author.
    Zheng, J
    Natl Institute Radiol Science.
    A certified reference material for radionuclides in the water sample from Irish Sea (IAEA-443)2011In: JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, ISSN 0236-5731, Vol. 288, no 2, 603-611 p.Article in journal (Refereed)
    Abstract [en]

    A new certified reference material (CRM) for radionuclides in sea water from the Irish sea (IAEA-443) is described and the results of the certification process are presented. Ten radionuclides (H-3, K-40, Sr-90, Cs-137, U-234, U-235, U-238, Pu-238, Pu239+240 and Am-241) have been certified, and information values on massic activities with 95% confidence intervals are given for four radionuclides (Th-230, Th-232, Pu-239 and Pu-240). Results for less frequently reported radionuclides (Tc-99, Th-228, Np-237 and Pu-241) are also reported. The CRM can be used for quality assurance/quality control of the analysis of radionuclides in water samples, for the development and validation of analytical methods and for training purposes. The material is available in 5 L units from IAEA (http://nucleus.iaea.org/rpst/index.htm).

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