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2025 (English)In: 2025 IEEE Workshop on Topological Data Analysis and Visualization (TopoInVis), Institute of Electrical and Electronics Engineers (IEEE) , 2025, p. 53-62Conference paper, Published paper (Refereed)
Abstract [en]
Photon-Counting Computed Tomography (PCCT) is a novel imaging modality that simultaneously acquires volumetric data at multiple X-ray energy levels, generating separate volumes that capture energy-dependent attenuation properties. Attenuation refers to the reduction in X-ray intensity as it passes through different tissues or materials, which depends on their density and atomic composition. This spectral information enhances tissue and material differentiation, enabling more accurate diagnosis and analysis. However, the resulting multivolume datasets are often complex and redundant, making visualization and interpretation challenging. To address these challenges, we propose a method for fusing spectral PCCT data into a single representative volume that enables direct volume rendering and segmentation by leveraging both shared and complementary information across different channels. Our approach starts by computing 2D histograms between pairs of volumes to identify those that exhibit prominent structural features. These histograms reveal relationships and variations that may be difficult to discern from individual volumes alone. Next, we construct an extremum graph from the 2D histogram of two minimally correlated yet complementary volumes—selected to capture both shared and distinct features—thereby maximizing the information content. The graph captures the topological distribution of histogram extrema. By extracting prominent structure within this graph and projecting each grid point in histogram space onto it, we reduce the dimensionality to one, producing a unified volume. This representative volume retains key structural and material characteristics from the original spectral data while significantly reducing the analysis scope from multiple volumes to one. The result is a topology-aware, information-rich fusion of multi-energy CT datasets that facilitates more effective visualization and segmentation.
Place, publisher, year, edition, pages
Institute of Electrical and Electronics Engineers (IEEE), 2025
Keywords
Multi-spectral CT, extremum graph, volume rendering, medical image segmentation, multidimensional transfer function, Computed tomography, Pipelines, Data visualization, Feature extraction
National Category
Computer graphics and computer vision Human Computer Interaction Radiology and Medical Imaging Medical Imaging
Identifiers
urn:nbn:se:liu:diva-221905 (URN)10.1109/TopoInVis68599.2025.00010 (DOI)001720170800006 ()2-s2.0-105032093960 (Scopus ID)9798331579920 (ISBN)9798331579937 (ISBN)
Conference
IEEE Workshop on Topological Data Analysis and Visualization (TopoInVis), 02-03 November 2025, Vienna, Austria
Funder
Swedish Research Council, 2023-04806Swedish Research Council, 2019-05487Wallenberg AI, Autonomous Systems and Software Program (WASP)Swedish e‐Science Research Center
2026-03-162026-03-162026-04-14