Leif Matthiesen, an evergreen member and supporter of the American Society for Reproductive Immunology (ASRI), died on April 29, 2017, following a hard fought battle with glioblastoma. We all hoped that Leif being a fearless person and a fun‐loving physician scientist would beat all the odds against this dreaded disease and come out of it with flying colors. Alas, our hopes were given a serious thought by the Almighty. We as a community of friends and scientific colleagues are saddened by the loss of such a wonderful human being and a noteworthy member of the ASRI.