EOOLT 2010 was the third edition of the EOOLT workshop series. The workshop is intended to bring together researchers and practitioners fromdifferent equation-based object-oriented (EOO) modeling language communities. This year’s workshop also expands the scope to include the whole design space of languages for cyber-physical systems, where physical dynamics are mixed with networks and software. The workshop gathered 31 participants to present and discuss thirteen different papers grouped into the four areas of real-time oriented modeling languages and tools, modeling language design, simulation and model compilation, and modeling and simulation tools.