Biogas production through anaerobic digestion is an integral part of the transition toward a biobased and circular economy and its expansion is foreseen in many parts of the world as well as in Europe. In Sweden, a governmental inquiry suggested biogas production to be increased from about 2 TWh today to 7 TWh by 2030. This rapid expansion would require installation of several new biogas plants across the country. However, the location of biogas plants can greatly affect its business performance and there are several geographic and socio-political factors that would limit the choice of location. Through dialogue with existing biogas producing companies and a few other related actors, we identified 12 factors that are commonly considered in the site-selection of biogas plants in Sweden or are considered to be important in the years to come. These factors are grouped into those related to supply and demand (feedstock supply, biogas demand, digestate demand, and carbon dioxide demand), infrastructure and synergies (available infrastructure, adjacent existing industries), land-use and zoning (nearby housing, zoning, and historic preservation sites), and socio-political context (political strategies and goals, organizational capability, and local social acceptance). We discuss how these factors can be used under rapidly transforming conditions in Sweden through different site-selection logics and highlight the importance of spatially explicit analysis for individual or coordinated decision making in future. Our method of enquiry and analysis, and to a certain degree the factors, can be also relevant for other countries, particularly in Europe. This study paves the way for more in-depth investigation of the question of site-selection of biogas plants in Sweden; both in the direction of detailed analysis at the local level, or screening analysis on the regional or national level for improved coordinated actions.