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Defecation Symptoms in Relation to Stool Consistency Significantly Reflect the Dyssynergic Pattern in High-resolution Anorectal Manometry in Constipated Patients
Linköping University, Department of Biomedical and Clinical Sciences, Division of Inflammation and Infection. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Mag- tarmmedicinska kliniken.ORCID iD: 0000-0002-6655-1089
Linköping University, Department of Health, Medicine and Caring Sciences, Division of Diagnostics and Specialist Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Mag- tarmmedicinska kliniken.ORCID iD: 0000-0002-3463-9705
Macquarie Univ, Australia.
Linköping University, Department of Biomedical and Clinical Sciences, Division of Inflammation and Infection. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Mag- tarmmedicinska kliniken.ORCID iD: 0000-0003-0836-3140
2024 (English)In: Journal of Clinical Gastroenterology, ISSN 0192-0790, E-ISSN 1539-2031, Vol. 58, no 1, p. 57-63Article in journal (Refereed) Published
Abstract [en]

Goals: To evaluate the usefulness of a 2-week patient-completed bowel habit and symptom diary as a screening tool for disordered rectoanal coordination (DRC).Background: DRC is an important subgroup of chronic constipation that benefits from biofeedback treatment. Diagnosis of DRC requires a dyssynergic pattern (DP) of attempted defecation in high-resolution anorectal manometry (HRAM) and at least 1 other positive standardized examination, such as the balloon expulsion test or defecography. However, HRAM is generally limited to tertiary gastroenterology centres and finding tools for selecting patients for referral for further investigations would be of clinical value.Study: Retrospective data from HRAM and a 2-week patient-completed bowel habit and symptom diary from 99 chronically constipated patients were analyzed.Results: Fifty-seven percent of the patients had a DP pattern during HRAM. In the DP group, 76% of bowel movements with loose or normal stool resulted in a sense of incomplete evacuation compared with 55% of the non-DP group (P=0.004). Straining and sensation of incomplete evacuation with the loose stool were significantly more common in the DP group (P=0.032). Hard stool was a discriminator for non-DP (P=0.044). Multiple logistic regression including incomplete evacuation and normal stool predicted DP with a sensitivity of 82% and a specificity of 50%.Conclusions: The sensation of incomplete evacuation with loose or normal stool could be a potential discriminator in favor of DP in chronically constipated patients. The bowel habit and symptom diary may be a useful tool for stratifying constipated patients for further investigation of suspected DRC.

Place, publisher, year, edition, pages
LIPPINCOTT WILLIAMS & WILKINS , 2024. Vol. 58, no 1, p. 57-63
Keywords [en]
anorectal functions; constipation; pelvic floor disorder; biofeedback
National Category
Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:liu:diva-204380DOI: 10.1097/MCG.0000000000001794ISI: 001228325600007PubMedID: 36730549OAI: oai:DiVA.org:liu-204380DiVA, id: diva2:1868956
Note

Funding Agencies|FORSS-Research Council of Southeast Sweden; Region Ostergotland, Sweden

Available from: 2024-06-12 Created: 2024-06-12 Last updated: 2025-02-11

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Ingemansson, AnnaWalter, SusannaSjödahl, Jenny
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Division of Inflammation and InfectionFaculty of Medicine and Health SciencesMag- tarmmedicinska klinikenDivision of Diagnostics and Specialist Medicine
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