Comprehensive characterization of European house dust contaminants: Concentrations and profiles, geographical variability, and implications for chemical regulation and health riskNILU, Norway.
NILU, Norway.
INERIS, Parc Technologique Alata BP2, France.
National and Kapodistrian University of Athens, Department of Chemistry, Greece.
University of Luxembourg, Luxembourg Centre for Systems Biomedicine (LCSB), Luxembourg.
AFIN-TS, Germany.
University of Córdoba, Department of Analytical Chemistry, Spain.
United States Environmental Protection Agency, Durham, USA.
University of Bordeaux, CNRS, Bordeaux INP, EPOC, , France.
NTNU, Department of Chemistry, Norway;Department of Analytical Chemistry, Nutrition and Food Sciences, Aquatic One Health Research Center (ARCUS), Universidade de Santiago de Compostela, Spain..
University of Antwerp, Toxicological Centre, Belgium.
University of Bordeaux, CNRS, Bordeaux INP, EPOC, France.
INERIS, Parc Technologique Alata BP2, , France.
Health Canada, Environmental Health Science and Research Bureau, 51 Sir Frederick Banting Driveway, Canada.
INEGI, Institute of Science and Innovation in Mechanical and Industrial Engineering, Portugal.
Umeå University, Department of Chemistry, Sweden.
IDAEA-CSIC, Water, Environmental and Food Chemistry Unit, Spain.
IVL Swedish Environmental Research Institute, Sweden.
University of Birmingham, School of Geography, Earth, and Environmental Sciences, United Kingdom.
Flemish Institute for Technological Research (VITO), Unit Materials and Chemistry (MATCH), Belgium.
Memorial University of Newfoundland, Canada.
The Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, , Australia.
University of Gdansk, Faculty of Chemistry, Poland.
INERIS, Parc Technologique Alata BP2, 6 France; Hydrosciences Montpellier, Univ Montpellier, IMT Mines Ales, IRD, CNRS, France.
Aristotle University of Thessaloniki, Department of Chemistry, Greece.
AFIN-TS, Germany.
IDAEA-CSIC, Water, Environmental and Food Chemistry Unit, Spain.
NILU, Norway.
Environmental Institute, Slovak Republic.
University of Antwerp, Toxicological Centre, Belgium.
RECETOX, Faculty of Science, Masaryk University, Czech Republic.
RECETOX, Faculty of Science, Masaryk University, Czech Republic.
Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, France.
The Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Woolloongabba, Australia.
University of Luxembourg, Luxembourg Centre for Systems Biomedicine (LCSB), Luxembourg.
RECETOX, Faculty of Science, Masaryk University, Czech Republic.
Nanjing University, Nanjing, China.
Environmental Institute, Slovak Republic.
University of Luxembourg, Luxembourg Centre for Systems Biomedicine (LCSB), Luxembourg.
Finnish Institute for Health and Welfare (THL), Department of Public Health, Finland.
National and Kapodistrian University of Athens, Department of Chemistry, Greece.
Flemish Institute for Technological Research (VITO), Unit Materials and Chemistry (MATCH), Belgium.
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2024 (English)In: Science of the Total Environment, ISSN 0048-9697, E-ISSN 1879-1026, Vol. 957, article id 177639Article in journal (Refereed) Published
Abstract [en]
This study investigated the concentration profiles and geographical variability of contaminants in house dust across Europe. A collaborative trial (CT) was organized by the NORMAN network using pooled dust and advanced chromatographic and mass spectrometric techniques combined with suspect screening and non-target screening (NTS). Over 1200 anthropogenic compounds were tentatively identified. Additionally, seventy-five individual samples were subjected to target analysis and NTS. The median concentrations of most contaminants varied <3-fold across Europe, and the contaminant profile of European dust was similar to that of North American dust, which was investigated in a previous CT. This similarity may be attributed to the use of similar consumer articles and building materials throughout the developed world. Multivariate data analysis revealed geographical trends in contaminant distribution, with north-south gradients across Europe. Geographical trends were more frequently found for compounds with rapid release (pharmaceuticals, personal care products, fragrances, pesticides, biocides) and smoke-related compounds. The concentrations of chlorinated paraffins, polycyclic aromatic hydrocarbons (PAHs), perfluorinated alkyl substances and stimulants generally increased from north to south, whereas the biocides levels decreased from north to south. Despite widespread presence of in-use contaminants in dusts, some of the highest risks come from compounds that have been restricted for decades or more. These include di(2-ethylhexyl) phthalate (DEHP), polychlorinated biphenyl (PCB) 118 and polybrominated diphenyl ethers 47, 99, and 153. DEHP remains the most abundant contaminant in European house dust, while the other compounds are classified as persistent organic pollutants (POPs). Moreover, there is a striking lack of reliable toxicity data, particularly for emerging compounds. For instance, although acceptable daily intakes (ADIs) were examined for 202 compounds, only 46 had consensus-based ADI values. The results highlight the need for proactive measures to prevent hazardous chemicals from entering the market and for careful selection of substitute chemicals, when such are needed, to avoid regrettable substitutions. © 2024
Place, publisher, year, edition, pages
Elsevier, 2024. Vol. 957, article id 177639
Keywords [en]
Air Pollutants; Air Pollution, Indoor; Dust; Environmental Monitoring; Europe; Humans; Polycyclic Aromatic Hydrocarbons; Risk Assessment; Europe; Chlorine compounds; Chromatographic analysis; Ethanol; Ethers; Fragrances; Halogenation; Oils and fats; Organic pollutants; Polychlorinated biphenyls; Titration; Toxicity; 4, 4’ isopropylidenediphenol; alkylphenol; aromatic compound; biocide; caffeine; chemical compound; chrysene; cotinine; fluoranthene; fluorene; hexane; nicotine; organophosphate; paraffin; perfluorinated alkyl substance; perfluorononanoic acid; pesticide; phenanthrene derivative; phthalic acid bis(2 ethylhexyl) ester; polychlorinated biphenyl; polycyclic aromatic hydrocarbon; pyrene; theobromine; unclassified drug; polycyclic aromatic hydrocarbon; Collaborative trial; Di(2-ethylhexyl)phthalate; Geographical trends; Geographical variability; House dust; Human exposome; Non-target screenings; Organic contaminant; Organic contaminant profiling; Risks assessments; concentration (composition); dust; geographical variation; health risk; mass spectrometry; organic pollutant; risk assessment; trend analysis; Article; chemical parameters; chemical regulation; chromatography; data analysis; dust; electrospray; european house dust contaminant; gas chromatography; geographical variability; health hazard; high performance liquid chromatography; limit of detection; limit of quantitation; mass fragmentography; mass spectrometry; measurement accuracy; nonhuman; persistent organic pollutant; quality control; quantitative analysis; quantitative structure activity relation; quantitative structure property relation; air pollutant; environmental monitoring; Europe; human; indoor air pollution; risk assessment; Polycyclic aromatic hydrocarbons
National Category
Environmental Sciences
Identifiers
URN: urn:nbn:se:liu:diva-211147DOI: 10.1016/j.scitotenv.2024.177639PubMedID: 39626414Scopus ID: 2-s2.0-85210753396OAI: oai:DiVA.org:liu-211147DiVA, id: diva2:1930939
Note
Funding agencies: TheNORMANAssociationWorkingGroup6onIndoorEnvironments andAmbientAirandCrossWorkingGrouponNTSareacknowledgedfor initiating the collaborative trial and geographic distribution study. The work at the University of Antwerp was financially supported by the Interuniversity Special Research Fund from Flanders (GISMO 01IB1320, Flexigut project), and the Exposome Centre of Excellence of the University of Antwerp (BOF grant, Antigoon database number 41222). The work at Masaryk University was supported by the Czech Science Foundation (GAˇ CR), project No. 22-32743S and the RECETOX Research Infrastructure (No LM2023069) financed by the Ministry of Education, Youth and Sports, and the European Union’s Horizon 2020 research and innovation program under grant agreement No 857560. Michal Novakowski, Adam Mickiewicz University, Pozna´n, Poland is acknowledged for assistance with sampling. BTA, DA & ELS acknowledge Randolph Singh and NTNU acknowledge Alexandros G. Asimakopoulos and Dr. Susana V. Gonzalez for technical assistance in the analysis of their samples. BTA acknowledges funding from the “Microbiomes in One Health” PhD training program, supported by the PRIDE doctoral research funding scheme (PRIDE/11823097) of the Luxembourg National Research Fund(FNR). ELS,DAacknowledgefundingsupportfrom the FNRforproject A18/BM/12341006.DAacknowledgesfundingfrom the University of Luxembourg Institute for Advanced Studies (IAS) for the Audacity project “LuxTIME”. The work at University of Bordeaux (UB) was supported by the PLATINE Infrastructure, financed by the “R´ egion Nouvelle Aquitaine” and the French Research Ministry (CPER A2E), by the French National Agency (TRANSPRO project; ANR-18CE04-0006), andbytheNouvelle Aquitaine Region (ETRACproject). UB acknowledge C. Gardia-Parege and E. Geneste for technical assistance in the analysis of their samples. TW acknowledges the funding from FORMAS(2020-01163). The work at IDAEA-CSIC was supported by the by the grant CEX2018–000794-S funded by MCIN/AEI (10.13039/ 501100011033) and by the Government of Catalonia (2021 SGR 00753). AA, FL and VD acknowledges funding from the French Ministry of Environment.
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