Chapter 1 accounts for the co-editors’ entry points to the curating of the Handbook. Following a brief description of the back-story, the history of the Network of Queer Death Studies, they situate their curating efforts in relation to the wider context of contemporary studies of death, dying, mourning, and afterlife, and present the methodological, theoretical, and ethico-political reflections that have guided the book’s coming into being. It is highlighted how queering, posthumanising, and decolonising approaches to both human and more-than-human death-worlds, and a bio- and geo-egalitarian queerfeminist ethos have guided the curating. Theoretical frameworks for analysing the multiple effects of current Anthropocene necropolitics, the proliferation of death-worlds and experiences of social and ecological unsettlement and defuturing that in both a human and nonhuman sense characterise the current times, are also discussed. Moreover, the chapter emphasises how the curating has been based on critical approaches, but also, on an affirmative ethics, explorations of alternative life/death ontologies and resistant commitments to mourning and remembrance, from the perspective of the marginalised in terms of gender, race, class, geopolitical positioning, sexuality, embodiment, embrainment, species, and other markers of hierarchised difference. Different kinds of grieving, lamentation, and politics of remembrance are foregrounded, including eco-grief.