Highlights from research on different nanocomposites and nanostructures for sensing and other energy related applications will be presented. The synthesized nanostructures and nanocomposites presented here were all obtained using the low temperature (amp;lt; 100 degrees C) chemical approach. Nanostructures featured by small foot-print and synthesized by the low temperature aqueous chemical approach allows the utilization of non-conventional solid and soft substrates like e.g. glass, plastic, textile and paper. We here present results from different metal oxide nanostructures employed for chemical sensing and some innovative energy related applications. Efficient sensitive and selective sensing of dopamine, melamine, and glucose are presented as some examples of self-powered sensors utilizing the electrochemical phenomenon i.e. transferring chemical energy into electrical signal. Further the use of nanomaterials for developing self-powered devices utilizing mechanical ambient energy is presented via piezoelectric and triboelectric effects. Here the self-powered devices and systems were relying on utilizing the electormechanical phenomenon i.e. transferring ambient mechanical energy into useful electrical energy. Finally the visibility of nanomaterials prepared by the low temperature chemical synthesis as possible low cost replacement of Pt electrodes for hydrogen production is briefly presented and discussed.