A fundamental problem in artificial intelligence is how to organize and coordinate agents to improve their performance and skills. In this paper, we consider simultaneously generating coalitions of agents and assigning the coalitions to independent tasks, and present an anytime algorithm for the simultaneous coalition structure generation and assignment problem. This optimization problem has many real-world applications, including forming goal-oriented teams of agents. To evaluate the algorithm’s performance, we extend established methods for synthetic problem set generation, and benchmark the algorithm against CPLEX using randomized data sets of varying distribution and complexity. We also apply the algorithm to solve the problem of assigning agents to regions in a major commercial strategy game, and show that the algorithm can be utilized in game-playing to coordinate smaller sets of agents in real-time.