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Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) procedure for colorectal liver metastasis
Univ Rochester, NY 14642 USA.
Univ Rochester, NY 14642 USA.
Clin Res Ctr Moscow, Russia.
Linköping University, Department of Biomedical and Clinical Sciences, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Surgery, Orthopaedics and Cancer Treatment, Department of Surgery in Linköping.
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2020 (English)In: International Journal of Surgery, ISSN 1743-9191, E-ISSN 1743-9159, Vol. 82, p. 103-108Article, review/survey (Refereed) Published
Abstract [en]

Since first described, Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) has garnered boisterous praise and fervent criticism. Its rapid adoption and employment for a variety of indications resulted in high perioperative morbidity and mortality. However recent risk stratification, refinement of technique to reduce the impact of stage I and progression along the learning curve have resulted in improved outcomes. The first randomized trial comparing ALPPS to two stage hepatectomy (TSH) for colorectal liver metastases (CRLM) was recently published demonstrating comparable perioperative morbidity and mortality with improved resectability and survival following ALPPS. In this review, as ALPPS enters the thirteenth year since conception, the current status of this contentious two stage technique is presented and best practices for deployment in the treatment of CRLM is codified.

Place, publisher, year, edition, pages
ELSEVIER , 2020. Vol. 82, p. 103-108
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Surgery
Identifiers
URN: urn:nbn:se:liu:diva-170963DOI: 10.1016/j.ijsu.2020.04.009ISI: 000578009200017PubMedID: 32305531OAI: oai:DiVA.org:liu-170963DiVA, id: diva2:1485151
Available from: 2020-11-01 Created: 2020-11-01 Last updated: 2020-11-01

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Björnsson, Bergthor
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Division of Surgery, Orthopedics and OncologyFaculty of Medicine and Health SciencesDepartment of Surgery in Linköping
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