Prediction of Obstructive Coronary Artery Disease from Myocardial Perfusion Scintigraphy using Deep Neural NetworksShow others and affiliations
2021 (English)In: 2020 25TH INTERNATIONAL CONFERENCE ON PATTERN RECOGNITION (ICPR), IEEE COMPUTER SOC , 2021, p. 4442-4449Conference paper, Published paper (Refereed)
Abstract [en]
For diagnosis and risk assessment in patients with stable ischemic heart disease, myocardial perfusion scintigraphy is one of the most common cardiological examinations performed today. There are however many motivations for why an artificial intelligence algorithm would provide useful input to this task. For example to reduce the subjectiveness and save time for the nuclear medicine physicians working with this time consuming task. In this work we have developed a deep learning algorithm for multi-label classification based on a convolutional neural network to estimate the probability of obstructive coronary artery disease in the left anterior artery, left circumflex artery and right coronary artery. The prediction is based on data from myocardial perfusion scintigraphy studies conducted in a dedicated Cadmium-Zinc-Telluride cardio camera (D-SPECT Spectrum Dynamics). Data from 588 patients was available, with stress images in both upright and supine position, as well as a number of auxiliary parameters such as angina symptoms and age. The data was used to train and evaluate the algorithm using 5-fold cross-validation. We achieve state-of-the-art results for this task with an area under the receiver operating characteristics curve of 0.89 as average on per-vessel level and 0.95 on per-patient level.
Place, publisher, year, edition, pages
IEEE COMPUTER SOC , 2021. p. 4442-4449
Series
International Conference on Pattern Recognition, ISSN 1051-4651
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:liu:diva-178787DOI: 10.1109/ICPR48806.2021.9412674ISI: 000678409204076ISBN: 978-1-7281-8808-9 (print)OAI: oai:DiVA.org:liu-178787DiVA, id: diva2:1589914
Conference
25th International Conference on Pattern Recognition (ICPR), ELECTR NETWORK, jan 10-15, 2021
Note
Funding Agencies|AIDA/Medtech4Health
2021-09-012021-09-012021-09-01