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Immunrelaterade biverkningari tarm, lever, lungor och njurar: BIVERKNINGAR I SAMBAND MED IMMUNTERAPI MOT CANCER, DEL 1 [Overview of immune-related side effects from immune checkpoint inhibitors. Part 1: Gastrointestinal, lung and kidney toxicity]
Karolinska universitetssjukhuset, Stockholm, Sverige.
Karolinska universitetssjukhuset, Stockholm, Sverige.
Karolinska universitetssjukhuset, Stockholm, Sverige.
Karolinska universitetssjukhuset, Stockholm, Sverige.
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2021 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 118Article, review/survey (Refereed) Published
Abstract [en]

In the past decade, immunotherapy with checkpoint inhibitors has revolutionized the field of oncology. Checkpoint inhibitors have been approved for several types of cancer and thousands of patients in Sweden now receive oncological immunotherapy annually. Immune-related side effects are common and can occur in almost any organ. These side effects are different from those that occur with traditional oncological treatments. The side effects are usually mild, but can be serious and even lethal. In a short time, health care providers have had to readjust to be able to handle these side effects. Early and correct diagnosis of immune-related side effects, proper management and a multidisciplinary approach is crucial. Here, we give an overview of the presentation, diagnosis and treatment of immune-related side effects, with emphasis of those occurring in gastrointestinal organs, lungs and kidneys.

Abstract [sv]

Immunterapi med immunkontrollpunktshämmare har revolutionerat den onkologiska behandlingen under detsenaste årtiondet

Immunrelaterade biverkningar är vanliga och kan uppstå i så gott som alla kroppens organ. Biverkningarnakan vara allvarliga, och de skiljer sig mycket från dem som förekommer vid traditionella onkologiska behandlingar.

På relativt kort tid har vården fått ställa om för att kunna ta hand om immunterapibehandlade patienter på bästa sätt.

I två artiklar ges en översikt över de vanligast förekommande immunrelaterade biverkningarna. I denna,den första delen, är fokus på biverkningar som kan uppstå i mag–tarmkanalen, lungor och njurar.

Place, publisher, year, edition, pages
Sveriges Läkarförbund , 2021. Vol. 118
National Category
Gastroenterology and Hepatology Clinical Medicine
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URN: urn:nbn:se:liu:diva-185178PubMedID: 35080767OAI: oai:DiVA.org:liu-185178DiVA, id: diva2:1659058
Available from: 2022-05-18 Created: 2022-05-18 Last updated: 2025-02-18

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Eberhardson, Michael

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Division of Diagnostics and Specialist MedicineFaculty of Medicine and Health SciencesMag- tarmmedicinska kliniken
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Gastroenterology and HepatologyClinical Medicine

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