Community-led total sanitation (CLTS) is increasingly promoted globally as an innovative approach to addressing the sanitation challenge in developing countries, especially in the rural areas where access to sanitation remains poor. However, a significant challenge in CLTS is poor management of faecal sludge when pits are full. In this regard, composting toilets offer a potentially viable and ecologically sound method for effective and efficient faecal sludge management, by providing fertilisers that act as soil conditioners, and ultimately contribute to clean environment, food security, good health, and poverty alleviation. Despite these advantages, there is limited knowledge on why and how composting toilets can be successfully integrated into CLTS initiatives. In this paper, we use the case of Ghana to demonstrate that integrating composting toilets into the CLTS approach is a feasible option for sustainable and environmentally friendly faecal sludge management in rural areas where agriculture is the predominant livelihood activity.