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Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus- A report from the Atherosclerosis Risk in Communities (ARIC) study.
Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Local Health Care Services in East Östergötland, Department of Internal Medicine in Norrköping. Linköping University, Department of Health, Medicine and Caring Sciences, Division of Diagnostics and Specialist Medicine. Cardiovascular Division, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA, USA.ORCID iD: 0000-0002-4757-9051
Cardiovascular Division, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA, USA.
Faculdade Ciˆencias M´edicas de Minas Gerais, Fundaç˜ao Educacional Lucas Machado, Belo Horizonte, Brazil.
Cardiovascular Division, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA, USA.
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2022 (English)In: Diabetes Research and Clinical Practice, ISSN 0168-8227, E-ISSN 1872-8227, Vol. 194, article id 110164Article in journal (Refereed) Published
Abstract [en]

In this community-based cohort of 5861 individuals followed for median 7.2 years, the discriminatory ability of NT-proBNP alone in predicting mortality was similar to that of multiple conventional markers of risk in people without diabetes. In people with diabetes, NT-proBNP alone discriminated risk of mortality better than conventional risk factors.

Place, publisher, year, edition, pages
Elsevier, 2022. Vol. 194, article id 110164
Keywords [en]
B-type natriuretic peptide, Biomarkers, Diabetes mellitus, Epidemiology, Mortality, Risk prediction
National Category
Endocrinology and Diabetes
Identifiers
URN: urn:nbn:se:liu:diva-192637DOI: 10.1016/j.diabres.2022.110164ISI: 001010866400010PubMedID: 36410558OAI: oai:DiVA.org:liu-192637DiVA, id: diva2:1746023
Note

Funding: National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services [HHSN268201700001I, HHSN268201700002I, HHSN268201700003I, HHSN268201700005I, HHSN268201700004I, R01 HL-134320]; Swedish Heart Association; Swedish Society of Medicine; Region Ostergotland, Sweden; Lilly; Rubin Medical; Sanofi; Novartis; Novo Nordisk; Bayer AG; Galmed; Occlutech; Impulse Dynamics; Actelion; Alnylam; Amgen; AstraZeneca; Bellerophon; Bayer; BMS; Celladon; Cytokinetics; Eidos; Gilead; GSK; Ionis; Mesoblast; MyoKardia; NIH/NHLBI; Neurotronik; NovoNordisk; Respicardia; Sanofi Pasteur; Theracos; US2.AI

Available from: 2023-03-27 Created: 2023-03-27 Last updated: 2023-09-01

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Wijkman, Magnus

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Faculty of Medicine and Health SciencesDepartment of Internal Medicine in NorrköpingDivision of Diagnostics and Specialist Medicine
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