In today's industry development, the integration of manufacturing and logistics industries has received increasing attention from the international community. The Chinese government has set a strategic agenda for the deep integration and innovative development of logistics and manufacturing industries (DIIDLMI). However, it is still unclear what impact DIIDLMI has on the development of two industries. Especially with significant differences in resource endowments, it is interesting to see whether such impacts vary between coastal and inland regions. Therefore, this study focuses on the regional collaborative development mechanism and analyzes the performance of DIIDLMI by using the Spatial Durbin Model with provincial data in China. The analysis result indicates that, first, DIIDLMI has positive local effect and positive spatial spillover effect on digital intelligence technology development of the two industries, positive spatial spillover effect on low-carbon transformation and profit level of the logistics industry, positive local effect on low-carbon transformation of the manufacturing industry, and positive local effect on profit level of the two industries. Second, we also obtain some counterintuitive results, i.e., DIIDLMI has no local effect on low-carbon transformation of the logistics industry, no spatial spillover effect on low-carbon transformation and profit level of the manufacturing industry. Third, compared to coastal regions, DIIDLMI in inland regions has a more positive local effect on digital intelligence technology development of the logistics industry, a more positive spatial spillover effect on low-carbon transformation of the logistics industry, a more positive local effect on low-carbon transformation of the manufacturing industry, and a more positive local effect on profit level of the manufacturing industry. Finally, based on these results, policy recommendations are presented for promoting the related industrial development.