Energy security is a critical global challenge in the transition to sustainable development. Anaerobic digestion (AD) offers a promising renewable energy solution that mitigates environmental impacts. Algae, as biomass feedstock, have shown significant potential for bioenergy production; however, their complex chemical composition poses challenges to the efficiency of the AD process. To address these limitations, various pretreatment methods have been applied to enhance biogas production. In this study, we performed a comprehensive meta-analysis to evaluate the effects of different pretreatments on methane (CH4) yields from both microalgae and macroalgae. Our results demonstrate that biological, physical, and combined chemical-physical pretreatments significantly improve CH4 production in microalgae, with increases of up to 141%, 125%, and 151%, respectively. For macroalgae, physical pretreatments were the most effective, leading to a 129% increase in CH4 yield. We also estimate that utilizing just 10% of the global algal biomass production (3.6 Mt) could generate over 5.5 TWh y-1 of energy. This potential could be doubled with the application of appropriate pretreatment strategies. These findings highlight the role of algae in advancing renewable energy production and contribute to the growing body of knowledge on optimizing AD processes for cleaner energy generation.