liu.seSearch for publications in DiVA
Operational message
There are currently operational disruptions. Troubleshooting is in progress.
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Reinterventions in patients with congenital aortic stenosis and a commissurotomy
Umeå Univ, Sweden.
Umeå Univ, Sweden.
Umeå Univ, Sweden.
Umeå Univ, Sweden.
Show others and affiliations
2025 (English)In: Open heart, E-ISSN 2053-3624, Vol. 12, no 1, article id e003128Article in journal (Refereed) Published
Abstract [en]

Background In congenital aortic stenosis (CAS), commissurotomy is an option in patients not suitable to receive a valve prosthesis. However, there is often a need for future additional interventions on the aortic valve. The fate of the aortic valve is, however, essentially unknown. This study reports the need for reinterventions after surgical commissurotomy, based on a national register. Materials and methods The national register on congenital heart diseases (CHDs) was searched for patients with CAS, simple or associated with other CHD and an index commissurotomy with later data from follow-up. Results 300 patients with CAS and an index commissurotomy (mean age at the operation 7.4 +/- 7.8 years, 72.4% males) were identified. After an observation time of 27.4 +/- 10.0 years, 54.7% of the patients had a reintervention that occurred 14.2 +/- 10.1 years after the index operation. The cumulative incidence of reintervention was approximately 25% 10 years after and 60% 30 years after the index intervention. The prevalence of left ventricular hypertrophy (LVH) was higher among those that needed reintervention (41.3 vs 26.8%, p=0.023). Furthermore, eight patients died with a cumulative incidence of 7% 30 years after the index intervention, where most were (7/8) without reintervention (p=0.025). There were no additional important differences between patients with and without reintervention. The prevalence of left ventricular dysfunction and New York Heart Association class >1 was low. Conclusion Most (54.7%) patients with a commissurotomy, more than half of them within 30 years and eventually all will need a reintervention. This is important information to patients, especially for women in childbearing age. The higher prevalence of LVH in the group with reintervention needs attention during follow-up. Furthermore, those without reintervention, for unknown reasons, had a higher mortality. Our data strengthen the arguments for close outpatient follow-up among patients with a previous commissurotomy.

Place, publisher, year, edition, pages
BMJ PUBLISHING GROUP , 2025. Vol. 12, no 1, article id e003128
Keywords [en]
Aortic Valve Stenosis; Congenital Abnormalities; Heart Valve Prosthesis Implantation; Epidemiology; Heart Defects, Congenital
National Category
Cardiology and Cardiovascular Disease
Identifiers
URN: urn:nbn:se:liu:diva-212329DOI: 10.1136/openhrt-2024-003128ISI: 001437257100001PubMedID: 40032608OAI: oai:DiVA.org:liu-212329DiVA, id: diva2:1945620
Note

Funding Agencies|Region Vasterbotten [RV-996417]; Visare Norr [994832]; Hjart-Lungfonden [2023-0593]

Available from: 2025-03-19 Created: 2025-03-19 Last updated: 2025-03-19

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Trzebiatowska-Krzynska, Alexandra
By organisation
Department of Health, Medicine and Caring SciencesFaculty of Medicine and Health SciencesDepartment of Cardiology in Linköping
In the same journal
Open heart
Cardiology and Cardiovascular Disease

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 25 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf