Smart textile actuators are gaining attention for applications in soft robotics and wearable electronics. These actuators can undergo controlled, reversible deformation in response to external stimuli like temperature changes or electric potential. Recent advancements focus on integrating smart yarns, fibre actuators, and functional materials directly in/on textiles. The mechanics of the textile substrate influence the actuation performance of these devices, which can enable complex movements. By using different weave patterns in combination with different yarns, the mechanical anisotropy of the substrate can be enhanced. Additive manufacturing offers a promising approach for fabricating these actuators, allowing rapid customization of active and passive material patterns. This study explores multi-layered PEDOT:PSS actuators 3D-printed onto various textile substrates via syringe-based extrusion. The effects of different weave patterns on bending actuation are examined, and the findings highlight the relationship between textile design, material composition, and fabrication methods in optimizing smart textile actuators.